The steric gate of dna polymerase ι regulates ribonucleotide incorporation and deoxyribonucleotide fidelity

Journal of Biological Chemistry

Volumn 289, Issue 13, 2014, Pages 9136-9145

  Donigan, Katherine A ^a   McLenigan, Mary P ^a   Yang, Wei ^a   Goodman, Myron F ^b   Woodgate, Roger ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLYMERS; SEEBECK EFFECT;

BASE SELECTIVITY; DNA POLYMERASE; HUMAN DNA POLYMERASE; NUCLEOTIDE POOLS; REPLICATIVE POLYMERASE; RIBONUCLEOTIDES; TRANSLESION DNA SYNTHESIS; WATSON-CRICK BASE PAIRING;

DNA;

DEOXYRIBONUCLEOTIDE; DNA POLYMERASE; DNA POLYMERASE IOTA; MAGNESIUM; MANGANESE; RIBONUCLEOTIDE; UNCLASSIFIED DRUG; DNA; DNA DIRECTED DNA POLYMERASE; PRIMER DNA; TYROSINE;

AMINO ACID SUBSTITUTION; ARTICLE; BASE PAIRING; CATALYSIS; CONTROLLED STUDY; DNA BINDING; DNA DAMAGE; DNA SEQUENCE; DNA SYNTHESIS; ENZYME ACTIVE SITE; MOLECULAR MODEL; PRIORITY JOURNAL; TRANSLESION SYNTHESIS; AMINO ACID SEQUENCE; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTAGENESIS; MUTATION; NUCLEOTIDE SEQUENCE;

AMINO ACID SEQUENCE; BASE PAIRING; CATALYTIC DOMAIN; CONSERVED SEQUENCE; DEOXYRIBONUCLEOTIDES; DNA; DNA DAMAGE; DNA PRIMERS; DNA-DIRECTED DNA POLYMERASE; HUMANS; MANGANESE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION; RIBONUCLEOTIDES; SUBSTRATE SPECIFICITY; TYROSINE;

EID: 84897457858     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.545442     Document Type: Article

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