Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival

Nature Communications

Volumn 5, Issue , 2014, Pages

  Khacho, Mireille ^a   Tarabay, Michelle ^a   Patten, David ^a   Khacho, Pamela ^a   MacLaurin, Jason G ^a   Guadagno, Jennifer ^b   Bergeron, Richard ^a,c   Cregan, Sean P ^b   Harper, Mary Ellen ^a   Park, David S ^a   Slack, Ruth S ^a  

^a UNIVERSITY OF OTTAWA   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; DYNAMIN; DYNAMIN RELATED PROTEIN 1; GLUCOSE; OXYGEN; UNCLASSIFIED DRUG;

ANOXIC CONDITIONS; BIOENERGETICS; CYTOLOGY; HOMEOSTASIS; METABOLISM; MITOCHONDRIAL DNA; OXYGEN; PHYSIOLOGICAL RESPONSE;

ACIDOSIS; AEROBIC METABOLISM; ANAEROBIC GLYCOLYSIS; ANAEROBIC METABOLISM; ANIMAL CELL; ARTICLE; BRAIN CELL; BRAIN CELL CULTURE; BRAIN MITOCHONDRION; CELL DEATH; CELL DIVISION; CELL FUNCTION; CELL FUSION; CELL METABOLISM; CELL STRUCTURE; CELL SURVIVAL; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; CONTROLLED STUDY; CYTOARCHITECTURE; EMBRYO; EX VIVO STUDY; FEMALE; HUMAN; HUMAN CELL; HYPOXIA; HYPOXIC CELL; IMMUNOFLUORESCENCE; IN VITRO STUDY; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL FISSION; MITOCHONDRIAL FUNCTION; MITOCHONDRIAL FUSION; MITOSIS; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; REOXYGENATION; STRESS INDUCED MITOCHONDRIAL HYPERFUSION PATHWAY;

ACIDOSIS; ADENOSINE TRIPHOSPHATE; ANIMALS; CELL LINE, TUMOR; CELL SURVIVAL; FEMALE; HUMANS; MALE; METABOLIC NETWORKS AND PATHWAYS; MICE; MITOCHONDRIA; MITOSIS; OXIDATIVE PHOSPHORYLATION; OXYGEN;

EID: 84897382106     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4550     Document Type: Article

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