메뉴 건너뛰기




Volumn 95, Issue 2, 2014, Pages 243-250

Bruton's tyrosine kinase-an integral protein of B cell development that also has an essential role in the innate immune system

Author keywords

Inflammation; TLRs; XLA

Indexed keywords

BREAKPOINT CLUSTER REGION PROTEIN; BRUTON TYROSINE KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN SH3; AGAMMAGLOBULINAEMIA TYROSINE KINASE; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN TYROSINE KINASE;

EID: 84897096601     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.0513307     Document Type: Review
Times cited : (89)

References (89)
  • 1
    • 0000419304 scopus 로고
    • Agammaglobulinemia
    • Bruton, O. C. (1952) Agammaglobulinemia. Pediatrics 9, 722-728.
    • (1952) Pediatrics , vol.9 , pp. 722-728
    • Bruton, O.C.1
  • 2
    • 0015443981 scopus 로고
    • Circulating B-cells in patients with immunodeficiency
    • Cooper, M. D., Lawton, A. R. (1972) Circulating B-cells in patients with immunodeficiency. Am. J. Pathol. 69, 513-528.
    • (1972) Am. J. Pathol. , vol.69 , pp. 513-528
    • Cooper, M.D.1    Lawton, A.R.2
  • 3
    • 70349741029 scopus 로고    scopus 로고
    • Genetics of hypogammaglobulinemia: What do we really know?
    • Conley, M. E. (2009) Genetics of hypogammaglobulinemia: what do we really know? Curr. Opin. Immunol. 21, 466-471.
    • (2009) Curr. Opin. Immunol. , vol.21 , pp. 466-471
    • Conley, M.E.1
  • 6
    • 0027358430 scopus 로고
    • The Bruton's tyrosine kinase gene is expressed throughout B cell differentiation, from early precursor B cell stages preceding immunoglobulin gene rearrangement up to mature B cell stages
    • De Weers, M., Verschuren, M. C., Kraakman, M. E., Mensink, R. G., Schuurman, R. K., van Dongen, J. J., Hendriks, R. W. (1993) The Bruton's tyrosine kinase gene is expressed throughout B cell differentiation, from early precursor B cell stages preceding immunoglobulin gene rearrangement up to mature B cell stages. Eur. J. Immunol. 23, 3109-3114.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 3109-3114
    • De Weers, M.1    Verschuren, M.C.2    Kraakman, M.E.3    Mensink, R.G.4    Schuurman, R.K.5    van Dongen, J.J.6    Hendriks, R.W.7
  • 8
    • 0029792213 scopus 로고    scopus 로고
    • Inactivation of Btk by insertion of lacZ reveals defects in B cell development only past the pre-B cell stage
    • Hendriks, R. W., de Bruijn, M. F., Maas, A., Dingjan, G. M., Karis, A., Grosveld, F. (1996) Inactivation of Btk by insertion of lacZ reveals defects in B cell development only past the pre-B cell stage. EMBO J. 15, 4862-4872.
    • (1996) EMBO J. , vol.15 , pp. 4862-4872
    • Hendriks, R.W.1    de Bruijn, M.F.2    Maas, A.3    Dingjan, G.M.4    Karis, A.5    Grosveld, F.6
  • 10
    • 41949142535 scopus 로고    scopus 로고
    • Analysis of clinical presentations of Bruton disease: A review of 20 years of accumulated data from pediatric patients at Severance Hospital
    • Chun, J. K., Lee, T. J., Song, J. W., Linton, J. A., Kim, D. S. (2008) Analysis of clinical presentations of Bruton disease: a review of 20 years of accumulated data from pediatric patients at Severance Hospital. Yonsei Med. J. 49, 28-36.
    • (2008) Yonsei Med. J. , vol.49 , pp. 28-36
    • Chun, J.K.1    Lee, T.J.2    Song, J.W.3    Linton, J.A.4    Kim, D.S.5
  • 14
    • 59449099811 scopus 로고    scopus 로고
    • Clinical and molecular analysis of 49 patients with X-linked agammaglobulinemia from a single center in Argentina
    • Basile, N., Danielian, S., Oleastro, M., Rosenzweig, S., Prieto, E., Rossi, J., Roy, A., Zelazko, M. (2009) Clinical and molecular analysis of 49 patients with X-linked agammaglobulinemia from a single center in Argentina. J. Clin. Immunol. 29, 123-129.
    • (2009) J. Clin. Immunol. , vol.29 , pp. 123-129
    • Basile, N.1    Danielian, S.2    Oleastro, M.3    Rosenzweig, S.4    Prieto, E.5    Rossi, J.6    Roy, A.7    Zelazko, M.8
  • 17
  • 20
    • 33750973379 scopus 로고    scopus 로고
    • BTKbase: The mutation database for X-linked agammaglobulinemia
    • Väliaho, J., Smith, C. I., Vihinen, M. (2006) BTKbase: the mutation database for X-linked agammaglobulinemia. Human Mutat. 27, 1209-1217.
    • (2006) Human Mutat. , vol.27 , pp. 1209-1217
    • Väliaho, J.1    Smith, C.I.2    Vihinen, M.3
  • 25
    • 0347482409 scopus 로고    scopus 로고
    • B-cell antigen-receptor signalling in lymphocyte development
    • Wang, L. D., Clark, M. R. (2003) B-cell antigen-receptor signalling in lymphocyte development. Immunology 110, 411-420.
    • (2003) Immunology , vol.110 , pp. 411-420
    • Wang, L.D.1    Clark, M.R.2
  • 26
    • 1842477169 scopus 로고    scopus 로고
    • STAT5 activation underlies IL7 receptor-dependent B cell development
    • Goetz, C. A., Harmon, I. R., O'Neil, J. J., Burchill, M. A., Farrar, M. A. (2004) STAT5 activation underlies IL7 receptor-dependent B cell development. J. Immunol. 172, 4770-4778.
    • (2004) J. Immunol. , vol.172 , pp. 4770-4778
    • Goetz, C.A.1    Harmon, I.R.2    O'Neil, J.J.3    Burchill, M.A.4    Farrar, M.A.5
  • 28
    • 0028797453 scopus 로고
    • Function of the interleukin-2 (IL-2) receptor γ-chain in biologic responses of X-linked severe combined immunodeficient B cells to IL-2, IL-4, IL-13, and IL-15
    • Matthews, D. J., Clark, P. A., Herbert, J., Morgan, G., Armitage, R. J., Kinnon, C., Minty, A., Grabstein, K. H., Caput, D., Ferrara, P., Callard, T. (1995) Function of the interleukin-2 (IL-2) receptor γ-chain in biologic responses of X-linked severe combined immunodeficient B cells to IL-2, IL-4, IL-13, and IL-15. Blood 85, 38-42.
    • (1995) Blood , vol.85 , pp. 38-42
    • Matthews, D.J.1    Clark, P.A.2    Herbert, J.3    Morgan, G.4    Armitage, R.J.5    Kinnon, C.6    Minty, A.7    Grabstein, K.H.8    Caput, D.9    Ferrara, P.10    Callard, T.11
  • 29
    • 0025732935 scopus 로고
    • The role of recombinant stem cell factor in early B cell development. Synergistic interaction with IL-7
    • McNiece, I. K., Langley, K. E., Zsebo, K. M. (1991) The role of recombinant stem cell factor in early B cell development. Synergistic interaction with IL-7. J. Immunol. 146, 3785-3790.
    • (1991) J. Immunol. , vol.146 , pp. 3785-3790
    • McNiece, I.K.1    Langley, K.E.2    Zsebo, K.M.3
  • 30
    • 0026542446 scopus 로고
    • Differential roles of stromal cells, interleukin-7, and kit-ligand in the regulation of B lymphopoiesis
    • Billips, L. G., Petitte, D., Dorshkind, K., Narayanan, R., Chiu, C. P., Landreth, K. S. (1992) Differential roles of stromal cells, interleukin-7, and kit-ligand in the regulation of B lymphopoiesis. Blood 79, 1185-1192.
    • (1992) Blood , vol.79 , pp. 1185-1192
    • Billips, L.G.1    Petitte, D.2    Dorshkind, K.3    Narayanan, R.4    Chiu, C.P.5    Landreth, K.S.6
  • 32
    • 0001584969 scopus 로고    scopus 로고
    • The Tec family of cytoplasmic tyrosine kinases: Mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species
    • Smith, C. I., Islam, T. C., Mattsson, P. T., Mohamed, A. J., Nore, B. F., Vihinen, M. (2001) The Tec family of cytoplasmic tyrosine kinases: mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species. Bioessays 23, 436-446.
    • (2001) Bioessays , vol.23 , pp. 436-446
    • Smith, C.I.1    Islam, T.C.2    Mattsson, P.T.3    Mohamed, A.J.4    Nore, B.F.5    Vihinen, M.6
  • 35
    • 0033945186 scopus 로고    scopus 로고
    • The role of Bruton's tyrosine kinase in B-cell development and function: A genetic perspective
    • Satterthwaite, A. B., Witte, O. N. (2000) The role of Bruton's tyrosine kinase in B-cell development and function: a genetic perspective. Immunol. Rev. 175, 120-127.
    • (2000) Immunol. Rev. , vol.175 , pp. 120-127
    • Satterthwaite, A.B.1    Witte, O.N.2
  • 36
    • 0039710379 scopus 로고    scopus 로고
    • Structure of the PH domain and Btk motif from Bruton's tyrosine kinase: Molecular explanations for X-linked agammaglobulinaemia
    • Hyvonen, M., Saraste, M. (1997) Structure of the PH domain and Btk motif from Bruton's tyrosine kinase: molecular explanations for X-linked agammaglobulinaemia. EMBO J. 16, 3396-3404.
    • (1997) EMBO J. , vol.16 , pp. 3396-3404
    • Hyvonen, M.1    Saraste, M.2
  • 37
    • 0345561543 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinasedependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells
    • Varnai, P., Rother, K. I., Balla, T. (1999) Phosphatidylinositol 3-kinasedependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells. J. Biol. Chem. 274, 10983-10989.
    • (1999) J. Biol. Chem. , vol.274 , pp. 10983-10989
    • Varnai, P.1    Rother, K.I.2    Balla, T.3
  • 38
    • 0035844208 scopus 로고    scopus 로고
    • Interaction between the Btk PH domain and phosphatidylinositol-3,4,5-trisphosphate directly regulates Btk
    • Saito, K., Scharenberg, A. M., Kinet, J. P. (2001) Interaction between the Btk PH domain and phosphatidylinositol-3,4,5-trisphosphate directly regulates Btk. J. Biol. Chem. 276, 16201-16206.
    • (2001) J. Biol. Chem. , vol.276 , pp. 16201-16206
    • Saito, K.1    Scharenberg, A.M.2    Kinet, J.P.3
  • 40
    • 33749166076 scopus 로고    scopus 로고
    • Solution structure and phosphopeptide binding of the SH2 domain from the human Bruton's tyrosine kinase
    • Huang, K. C., Cheng, H. T., Pai, M. T., Tzeng, S. R., Cheng, J. W. (2006) Solution structure and phosphopeptide binding of the SH2 domain from the human Bruton's tyrosine kinase. J. Biomol. NMR 36, 73-78.
    • (2006) J. Biomol. NMR , vol.36 , pp. 73-78
    • Huang, K.C.1    Cheng, H.T.2    Pai, M.T.3    Tzeng, S.R.4    Cheng, J.W.5
  • 42
    • 0035798646 scopus 로고    scopus 로고
    • Crystal structure of Bruton's tyrosine kinase domain suggests a novel pathway for activation and provides insights into the molecular basis of X-linked agammaglobulinemia
    • Mao, C., Zhou, M., Uckun, F. M. (2001) Crystal structure of Bruton's tyrosine kinase domain suggests a novel pathway for activation and provides insights into the molecular basis of X-linked agammaglobulinemia. J. Biol. Chem. 276, 41435-41443.
    • (2001) J. Biol. Chem. , vol.276 , pp. 41435-41443
    • Mao, C.1    Zhou, M.2    Uckun, F.M.3
  • 44
    • 34248166604 scopus 로고    scopus 로고
    • A remote substrate docking mechanism for the tec family tyrosine kinases
    • Joseph, R. E., Min, L., Xu, R., Musselman, E. D., Andreotti, A. H. (2007) A remote substrate docking mechanism for the tec family tyrosine kinases. Biochemistry 46, 5595-5603.
    • (2007) Biochemistry , vol.46 , pp. 5595-5603
    • Joseph, R.E.1    Min, L.2    Xu, R.3    Musselman, E.D.4    Andreotti, A.H.5
  • 45
    • 8444247821 scopus 로고    scopus 로고
    • The SLP-76 family of adapter proteins
    • Wu, J. N., Koretzky, G. A. (2004) The SLP-76 family of adapter proteins. Semin. Immunol. 16, 379-393.
    • (2004) Semin. Immunol. , vol.16 , pp. 379-393
    • Wu, J.N.1    Koretzky, G.A.2
  • 47
    • 33746769770 scopus 로고    scopus 로고
    • The mechanism of IL-5 signal transduction
    • Adachi, T., Alam, R. (1998) The mechanism of IL-5 signal transduction. Am. J. Physiol. 275, C623-C633.
    • (1998) Am. J. Physiol. , vol.275
    • Adachi, T.1    Alam, R.2
  • 48
    • 84455205579 scopus 로고    scopus 로고
    • Toll-like receptor 4-, 7-, and 8-activated myeloid cells from patients with X-linked agammaglobulinemia produce enhanced inflammatory cytokines
    • Marron, T. U., Martinez-Gallo, M., Yu, J. E., Cunningham-Rundles, C. (2012) Toll-like receptor 4-, 7-, and 8-activated myeloid cells from patients with X-linked agammaglobulinemia produce enhanced inflammatory cytokines. J. Allergy Clin. Immunol. 129, 184-190. e1-4.
    • (2012) J. Allergy Clin. Immunol. , vol.129
    • Marron, T.U.1    Martinez-Gallo, M.2    Yu, J.E.3    Cunningham-Rundles, C.4
  • 49
    • 0037087438 scopus 로고    scopus 로고
    • Macrophage effector functions controlled by Bruton's tyrosine kinase are more crucial than the cytokine balance of T cell responses for microfilarial clearance
    • Mukhopadhyay, S., Mohanty, M., Mangla, A., George, A., Bal, V., Rath, S., Ravindran, B. (2002) Macrophage effector functions controlled by Bruton's tyrosine kinase are more crucial than the cytokine balance of T cell responses for microfilarial clearance. J. Immunol. 168, 2914-2921.
    • (2002) J. Immunol. , vol.168 , pp. 2914-2921
    • Mukhopadhyay, S.1    Mohanty, M.2    Mangla, A.3    George, A.4    Bal, V.5    Rath, S.6    Ravindran, B.7
  • 50
    • 33750840753 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase is required for TLR-induced IL-10 production
    • Schmidt, N. W., Thieu, V. T., Mann, B. A., Ahyi, A. N., Kaplan, M. H. (2006) Bruton's tyrosine kinase is required for TLR-induced IL-10 production. J. Immunol. 177, 7203-7210.
    • (2006) J. Immunol. , vol.177 , pp. 7203-7210
    • Schmidt, N.W.1    Thieu, V.T.2    Mann, B.A.3    Ahyi, A.N.4    Kaplan, M.H.5
  • 51
    • 37849019213 scopus 로고    scopus 로고
    • Defective Toll-like receptor 9-mediated cytokine production in B cells from Bruton's tyrosine kinase-deficient mice
    • Hasan, M., Lopez-Herrera, G., Blomberg, K. E., Lindvall, J. M., Berglof, A., Smith, C. I., Vargas, L. (2008) Defective Toll-like receptor 9-mediated cytokine production in B cells from Bruton's tyrosine kinase-deficient mice. Immunology 123, 239-249.
    • (2008) Immunology , vol.123 , pp. 239-249
    • Hasan, M.1    Lopez-Herrera, G.2    Blomberg, K.E.3    Lindvall, J.M.4    Berglof, A.5    Smith, C.I.6    Vargas, L.7
  • 52
    • 37549021148 scopus 로고    scopus 로고
    • Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase
    • Doyle, S. L., Jefferies, C. A., Feighery, C., O'Neill, L. A. (2007) Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase. J. Biol. Chem. 282, 36953-36960.
    • (2007) J. Biol. Chem. , vol.282 , pp. 36953-36960
    • Doyle, S.L.1    Jefferies, C.A.2    Feighery, C.3    O'Neill, L.A.4
  • 53
    • 0037492123 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor κB activation by Toll-like receptor 4
    • Jefferies, C. A., Doyle, S., Brunner, C., Dunne, A., Brint, E., Wietek, C., Walch, E., Wirth, T., O'Neill, L. A. (2003) Bruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor κB activation by Toll-like receptor 4. J. Biol. Chem. 278, 26258-26264.
    • (2003) J. Biol. Chem. , vol.278 , pp. 26258-26264
    • Jefferies, C.A.1    Doyle, S.2    Brunner, C.3    Dunne, A.4    Brint, E.5    Wietek, C.6    Walch, E.7    Wirth, T.8    O'Neill, L.A.9
  • 54
    • 84892163011 scopus 로고    scopus 로고
    • MyD88 is involved in myeloid as well as lymphoid hematopoiesis independent of the presence of a pathogen
    • Fiedler, K., Kokai, E., Bresch, S., Brunner, C. (2013) MyD88 is involved in myeloid as well as lymphoid hematopoiesis independent of the presence of a pathogen. Am. J. Blood Res. 3,124-140.
    • (2013) Am. J. Blood Res. , vol.3 , pp. 124-140
    • Fiedler, K.1    Kokai, E.2    Bresch, S.3    Brunner, C.4
  • 58
    • 33947210222 scopus 로고    scopus 로고
    • Impaired Toll-like receptor 8-mediated IL-6 and TNF-α production in antigen-presenting cells from patients with X-linked agammaglobulinemia
    • Sochorova, K., Horvath, R., Rozkova, D., Litzman, J., Bartunkova, J., Sediva, A., Spisek, R. (2007) Impaired Toll-like receptor 8-mediated IL-6 and TNF-α production in antigen-presenting cells from patients with X-linked agammaglobulinemia. Blood 109, 2553-2556.
    • (2007) Blood , vol.109 , pp. 2553-2556
    • Sochorova, K.1    Horvath, R.2    Rozkova, D.3    Litzman, J.4    Bartunkova, J.5    Sediva, A.6    Spisek, R.7
  • 61
    • 84862829783 scopus 로고    scopus 로고
    • The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophils
    • Honda, F., Kano, H., Kanegane, H., Nonoyama, S., Kim, E. S., Lee, S. K., Takagi, M., Mizutani, S., Morio, T. (2012) The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophils. Nat. Immunol. 13, 369-378.
    • (2012) Nat. Immunol. , vol.13 , pp. 369-378
    • Honda, F.1    Kano, H.2    Kanegane, H.3    Nonoyama, S.4    Kim, E.S.5    Lee, S.K.6    Takagi, M.7    Mizutani, S.8    Morio, T.9
  • 62
    • 79251565218 scopus 로고    scopus 로고
    • Neutrophil development and function critically depend on Bruton tyrosine kinase in a mouse model of X-linked agammaglobulinemia
    • Fiedler, K., Sindrilaru, A., Terszowski, G., Kokai, E., Feyerabend, T. B., Bullinger, L., Rodewald, H. R., Brunner, C. (2011) Neutrophil development and function critically depend on Bruton tyrosine kinase in a mouse model of X-linked agammaglobulinemia. Blood 117, 1329-1339.
    • (2011) Blood , vol.117 , pp. 1329-1339
    • Fiedler, K.1    Sindrilaru, A.2    Terszowski, G.3    Kokai, E.4    Feyerabend, T.B.5    Bullinger, L.6    Rodewald, H.R.7    Brunner, C.8
  • 65
    • 0345161418 scopus 로고    scopus 로고
    • Accelerated emigration of B lymphocytes in the Xid mouse
    • Cariappa, A., Kim, T. J., Pillai, S. (1999) Accelerated emigration of B lymphocytes in the Xid mouse. J. Immunol. 162, 4417-4423.
    • (1999) J. Immunol. , vol.162 , pp. 4417-4423
    • Cariappa, A.1    Kim, T.J.2    Pillai, S.3
  • 67
    • 0038221378 scopus 로고    scopus 로고
    • Chemotactic factor-induced recruitment and activation of Tec family kinases in human neutrophils. II. Effects of LFM-A13, a specific Btk inhibitor
    • Gilbert, C., Levasseur, S., Desaulniers, P., Dusseault, A. A., Thibault, N., Bourgoin, S. G., Naccache, P. H. (2003) Chemotactic factor-induced recruitment and activation of Tec family kinases in human neutrophils. II. Effects of LFM-A13, a specific Btk inhibitor. J. Immunol. 170, 5235-5243.
    • (2003) J. Immunol. , vol.170 , pp. 5235-5243
    • Gilbert, C.1    Levasseur, S.2    Desaulniers, P.3    Dusseault, A.A.4    Thibault, N.5    Bourgoin, S.G.6    Naccache, P.H.7
  • 68
    • 0037077219 scopus 로고    scopus 로고
    • Chemotactic factorinduced recruitment and activation of Tec family kinases in human neutrophils. Implication of phosphatidylinositol 3-kinases
    • Lachance, G., Levasseur, S., Naccache, P. H. (2002) Chemotactic factorinduced recruitment and activation of Tec family kinases in human neutrophils. Implication of phosphatidylinositol 3-kinases. J. Biol. Chem. 277, 21537-21541.
    • (2002) J. Biol. Chem. , vol.277 , pp. 21537-21541
    • Lachance, G.1    Levasseur, S.2    Naccache, P.H.3
  • 69
    • 77951027428 scopus 로고    scopus 로고
    • Tyrosine kinase Btk regulates E-selectin-mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) γ2 and PI3Kγ pathways
    • Mueller, H., Stadtmann, A., Van Aken, H., Hirsch, E., Wang, D., Ley, K., Zarbock, A. (2010) Tyrosine kinase Btk regulates E-selectin-mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) γ2 and PI3Kγ pathways. Blood 115, 3118-3127.
    • (2010) Blood , vol.115 , pp. 3118-3127
    • Mueller, H.1    Stadtmann, A.2    Van Aken, H.3    Hirsch, E.4    Wang, D.5    Ley, K.6    Zarbock, A.7
  • 70
    • 84856893681 scopus 로고    scopus 로고
    • Crucial role of SLP-76 and ADAP for neutrophil recruitment in mouse kidney ischemia-reperfusion injury
    • Block, H., Herter, J. M., Rossaint, J., Stadtmann, A., Kliche, S., Lowell, C. A., Zarbock, A. (2012) Crucial role of SLP-76 and ADAP for neutrophil recruitment in mouse kidney ischemia-reperfusion injury. J. Exp. Med. 209, 407-421.
    • (2012) J. Exp. Med. , vol.209 , pp. 407-421
    • Block, H.1    Herter, J.M.2    Rossaint, J.3    Stadtmann, A.4    Kliche, S.5    Lowell, C.A.6    Zarbock, A.7
  • 71
    • 77955394213 scopus 로고    scopus 로고
    • Btk-dependent Rac activation and actin rearrangement following Fc RI aggregation promotes enhanced chemotactic responses of mast cells
    • Kuehn, H. S., Radinger, M., Brown, J. M., Ali, K., Vanhaesebroeck, B., Beaven, M. A., Metcalfe, D. D., Gilfillan, A. M. (2010) Btk-dependent Rac activation and actin rearrangement following Fc∈RI aggregation promotes enhanced chemotactic responses of mast cells. J. Cell Sci. 123, 2576-2585.
    • (2010) J. Cell Sci. , vol.123 , pp. 2576-2585
    • Kuehn, H.S.1    Radinger, M.2    Brown, J.M.3    Ali, K.4    Vanhaesebroeck, B.5    Beaven, M.A.6    Metcalfe, D.D.7    Gilfillan, A.M.8
  • 72
    • 84860443493 scopus 로고    scopus 로고
    • The role of the tec kinase Bruton's tyrosine kinase (Btk) in leukocyte recruitment
    • Block, H., Zarbock, A. (2012) The role of the tec kinase Bruton's tyrosine kinase (Btk) in leukocyte recruitment. Int. Rev. Immunol. 31, 104-118.
    • (2012) Int. Rev. Immunol. , vol.31 , pp. 104-118
    • Block, H.1    Zarbock, A.2
  • 73
    • 0038723629 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase defect in dendritic cells from X-linked agammaglobulinaemia patients does not influence their differentiation, maturation and antigen-presenting cell function
    • Gagliardi, M. C., Finocchi, A., Orlandi, P., Cursi, L., Cancrini, C., Moschese, V., Miyawaki, T., Rossi, P. (2003) Bruton's tyrosine kinase defect in dendritic cells from X-linked agammaglobulinaemia patients does not influence their differentiation, maturation and antigen-presenting cell function. Clin. Exp. Immunol. 133, 115-122.
    • (2003) Clin. Exp. Immunol. , vol.133 , pp. 115-122
    • Gagliardi, M.C.1    Finocchi, A.2    Orlandi, P.3    Cursi, L.4    Cancrini, C.5    Moschese, V.6    Miyawaki, T.7    Rossi, P.8
  • 74
    • 84862812060 scopus 로고    scopus 로고
    • Dendritic and T cell response to influenza is normal in the patients with X-linked agammaglobulinemia
    • Liu, Y., Wu, Y., Lam, K. T., Lee, P. P., Tu, W., Lau, Y. L. (2012) Dendritic and T cell response to influenza is normal in the patients with X-linked agammaglobulinemia. J. Clin. Immunol. 32, 421-429.
    • (2012) J. Clin. Immunol. , vol.32 , pp. 421-429
    • Liu, Y.1    Wu, Y.2    Lam, K.T.3    Lee, P.P.4    Tu, W.5    Lau, Y.L.6
  • 77
    • 0028365273 scopus 로고
    • Hepatocyte growth factor and macrophage inflammatory protein 1 β: Structurally distinct cytokines that induce rapid cytoskeletal changes and subset-preferential migration in T cells
    • Adams, D. H., Harvath, L., Bottaro, D. P., Interrante, R., Catalano, G., Tanaka, Y., Strain, A., Hubscher, S. G., Shaw, S. (1994) Hepatocyte growth factor and macrophage inflammatory protein 1 β: structurally distinct cytokines that induce rapid cytoskeletal changes and subset-preferential migration in T cells. Proc. Natl. Acad. Sci. USA 91, 7144-7148.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 7144-7148
    • Adams, D.H.1    Harvath, L.2    Bottaro, D.P.3    Interrante, R.4    Catalano, G.5    Tanaka, Y.6    Strain, A.7    Hubscher, S.G.8    Shaw, S.9
  • 78
    • 80052781601 scopus 로고    scopus 로고
    • A novel role for Bruton's tyrosine kinase in hepatocyte growth factor-mediated immunoregulation of dendritic cells
    • Singhal, E., Kumar, P., Sen, P. (2011) A novel role for Bruton's tyrosine kinase in hepatocyte growth factor-mediated immunoregulation of dendritic cells. J. Biol. Chem. 286, 32054-32063.
    • (2011) J. Biol. Chem. , vol.286 , pp. 32054-32063
    • Singhal, E.1    Kumar, P.2    Sen, P.3
  • 79
    • 37549055771 scopus 로고    scopus 로고
    • CD303 (BDCA-2) signals in plasmacytoid dendritic cells via a BCR-like signalosome involving Syk, Slp65 and PLCγ2
    • Rock, J., Schneider, E., Grun, J. R., Grutzkau, A., Kuppers, R., Schmitz, J., Winkels, G. (2007) CD303 (BDCA-2) signals in plasmacytoid dendritic cells via a BCR-like signalosome involving Syk, Slp65 and PLCγ2. Eur. J. Immunol. 37, 3564-3575.
    • (2007) Eur. J. Immunol. , vol.37 , pp. 3564-3575
    • Rock, J.1    Schneider, E.2    Grun, J.R.3    Grutzkau, A.4    Kuppers, R.5    Schmitz, J.6    Winkels, G.7
  • 81
    • 4444260266 scopus 로고    scopus 로고
    • Platelet adhesion signalling and the regulation of thrombus formation
    • Gibbins, J. M. (2004) Platelet adhesion signalling and the regulation of thrombus formation. J. Cell Sci. 117, 3415-3425.
    • (2004) J. Cell Sci. , vol.117 , pp. 3415-3425
    • Gibbins, J.M.1
  • 82
    • 0031825550 scopus 로고    scopus 로고
    • Physical and functional association of the Src family kinases Fyn and Lyn with the collagen receptor glycoprotein VI-Fc receptor γ chain complex on human platelets
    • Ezumi, Y., Shindoh, K., Tsuji, M., Takayama, H. (1998) Physical and functional association of the Src family kinases Fyn and Lyn with the collagen receptor glycoprotein VI-Fc receptor γ chain complex on human platelets. J. Exp. Med. 188, 267-276.
    • (1998) J. Exp. Med. , vol.188 , pp. 267-276
    • Ezumi, Y.1    Shindoh, K.2    Tsuji, M.3    Takayama, H.4
  • 83
    • 0242411585 scopus 로고    scopus 로고
    • Tec regulates platelet activation by GPVI in the absence of Btk
    • Atkinson, B. T., Ellmeier, W., Watson, S. P. (2003) Tec regulates platelet activation by GPVI in the absence of Btk. Blood 102, 3592-3599.
    • (2003) Blood , vol.102 , pp. 3592-3599
    • Atkinson, B.T.1    Ellmeier, W.2    Watson, S.P.3
  • 84
    • 0032497629 scopus 로고    scopus 로고
    • A role for Bruton's tyrosine kinase (Btk) in platelet activation by collagen
    • Quek, L. S., Bolen, J., Watson, S. P. (1998) A role for Bruton's tyrosine kinase (Btk) in platelet activation by collagen. Curr. Biol. 8, 1137-1140.
    • (1998) Curr. Biol. , vol.8 , pp. 1137-1140
    • Quek, L.S.1    Bolen, J.2    Watson, S.P.3
  • 85
    • 84874405894 scopus 로고    scopus 로고
    • Bruton's tyrosine kinase mediates platelet receptor-induced generation of microparticles: A potential mechanism for amplification of inflammatory responses in rheumatoid arthritis synovial joints
    • Hsu, J., Gu, Y., Tan, S. L., Narula, S., Demartino, J. A., Liao, C. (2013) Bruton's tyrosine kinase mediates platelet receptor-induced generation of microparticles: a potential mechanism for amplification of inflammatory responses in rheumatoid arthritis synovial joints. Immunol. Lett. 150, 97-104.
    • (2013) Immunol. Lett. , vol.150 , pp. 97-104
    • Hsu, J.1    Gu, Y.2    Tan, S.L.3    Narula, S.4    Demartino, J.A.5    Liao, C.6
  • 88
    • 78650934360 scopus 로고    scopus 로고
    • Elevated cytokine production restores bone resorption by human Btk-deficient osteoclasts
    • Danks, L., Workman, S., Webster, D., Horwood, N. J. (2011) Elevated cytokine production restores bone resorption by human Btk-deficient osteoclasts. J. Bone Miner. Res. 26, 182-192.
    • (2011) J. Bone Miner. Res. , vol.26 , pp. 182-192
    • Danks, L.1    Workman, S.2    Webster, D.3    Horwood, N.J.4
  • 89
    • 45549099188 scopus 로고    scopus 로고
    • The tec family tyrosine kinase Btk regulates RANKL-induced osteoclast maturation
    • Lee, S. H., Kim, T., Jeong, D., Kim, N., Choi, Y. (2008) The tec family tyrosine kinase Btk regulates RANKL-induced osteoclast maturation. J. Biol. Chem. 283, 11526-11534.
    • (2008) J. Biol. Chem. , vol.283 , pp. 11526-11534
    • Lee, S.H.1    Kim, T.2    Jeong, D.3    Kim, N.4    Choi, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.