Stucture of the PH domain and Btk motif from Bruton's tyrosine kinase: Molecular explanations for X-linked agammaglobulinaemia

EMBO Journal

Volumn 16, Issue 12, 1997, Pages 3396-3404

  Hyvönen, Marko ^a   Saraste, Matti ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

Bruton's tyrosine kinase; Btk motif; Inositol phosphates; PH domain; X linked agammaglobulinaemia

Indexed keywords

CYSTEINE; HISTIDINE; INOSITOL PHOSPHATE; LIPID BINDING PROTEIN; PHOSPHATIDYLINOSITOL; PLECKSTRIN; PROTEIN TYROSINE KINASE; ZINC; AGAMMAGLOBULINAEMIA TYROSINE KINASE; INOSITOL 1,4,5 TRISPHOSPHATE; PHOSPHOPROTEIN; PLASMA PROTEIN; PLATELET PROTEIN P47;

AGAMMAGLOBULINEMIA; ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; B LYMPHOCYTE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL MATURATION; CELL MEMBRANE; CONTROLLED STUDY; GENE MUTATION; HUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; X CHROMOSOME LINKAGE; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; CHEMISTRY; GENETIC LINKAGE; GENETICS; IMAGE PROCESSING; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN SECONDARY STRUCTURE; SEQUENCE HOMOLOGY; X CHROMOSOME;

AGAMMAGLOBULINEMIA; AMINO ACID SEQUENCE; BINDING SITES; BLOOD PROTEINS; CRYSTALLOGRAPHY, X-RAY; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INOSITOL 1,4,5-TRISPHOSPHATE; LINKAGE (GENETICS); MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHOPROTEINS; PROTEIN STRUCTURE, SECONDARY; PROTEIN-TYROSINE KINASES; SEQUENCE HOMOLOGY, AMINO ACID; X CHROMOSOME;

EID: 0039710379     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.12.3396     Document Type: Article

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