Binding to WGR domain by salidroside activates parp1 and protects hematopoietic stem cells from oxidative stress

Antioxidants and Redox Signaling

Volumn 20, Issue 12, 2014, Pages 1853-1865

  Li, Xue ^a,b   Erden, Ozlem ^a   Li, Liang ^a   Ye, Qidong ^c   Wilson, Andrew ^a   Du, Wei ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b SOUTH CHINA NORMAL UNIVERSITY   (China)

^c SHANGHAI CHILDREN S MEDICAL CENTER   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; GLYCINE; MUTANT PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; SALIDROSIDE; TRYPTOPHAN; GLUCOSIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, MOUSE; PHENOL DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROTECTION; CELL RENEWAL; CELL STRESS; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DRUG MECHANISM; DRUG PROTEIN BINDING; ENZYME ACTIVATION; ENZYME PURIFICATION; GRAFT RECIPIENT; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; WILD TYPE; AMINO ACID SEQUENCE; ANIMAL; C57BL MOUSE; CHEMISTRY; DRUG EFFECTS; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; MOLECULAR GENETICS; RAT; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; ENZYME ACTIVATION; GLUCOSIDES; HEMATOPOIETIC STEM CELLS; HUMANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; OXIDATIVE STRESS; PHENOLS; POLY(ADP-RIBOSE) POLYMERASES; RATS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84897074999     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2013.5600     Document Type: Article

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