Depletion of Dnmt1-associated protein 1 triggers DNA damage and compromises the proliferative capacity of hematopoietic stem cells

International Journal of Hematology

Volumn 91, Issue 4, 2010, Pages 611-619

  Koizumi, Tomoe ^a   Negishi, Masamitsu ^a,b   Nakamura, Shunsuke ^a,b   Oguro, Hideyuki ^a,b   Satoh, Kaneshige ^a   Ichinose, Masaharu ^a   Iwama, Atsushi ^a,b  

^a CHIBA UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

DNA repair; Dnmt1 associated protein 1 (Dmap1); Genomic integrity; Hematopoietic stem cells (HSCs)

Indexed keywords

DNA; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 1 ASSOCIATED PROTEIN 1; PROTEIN P53; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL FUNCTION; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; GENOMICS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PROTEIN FUNCTION;

ANIMALS; CELL DIVISION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; DNA REPAIR; GENES, CDC; HEMATOPOIETIC STEM CELLS; HISTONES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NIH 3T3 CELLS; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53;

EID: 77954539850     PISSN: 09255710     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12185-010-0563-3     Document Type: Article

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