CD8+ dendritic cell-mediated tolerance of autoreactive CD4+ T cells is deficient in NOD mice and can be corrected by blocking CD40L

Journal of Leukocyte Biology

Volumn 95, Issue 2, 2014, Pages 325-336

  Price, Jeffrey D ^a   Beauchamp, Nicole M ^a   Rahir, Gwendoline ^a   Zhao, Yongge ^a   Rieger, Cosima C ^a   Lau Kilby, Annie W ^a   Tarbell, Kristin V ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

CD40; DEC 205; Peripheral tolerance; Type 1 diabetes

Indexed keywords

CD40 LIGAND; GAMMA INTERFERON; INTERLEUKIN 2; TRANSCRIPTION FACTOR FOXP3; ANTIBODY; ANTIGEN; CD40 ANTIGEN; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; LIGAND; PEPTIDE; TOLL LIKE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CD8+ DENDRITIC CELL; CELL EXPANSION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; FEMALE; IMMUNOLOGICAL TOLERANCE; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE; UPREGULATION; ANIMAL; CD40; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; DEC-205; DRUG ANTAGONISM; DRUG EFFECT; EXPERIMENTAL DIABETES MELLITUS; IMMUNOLOGY; METABOLISM; PATHOLOGY; PHENOTYPE; REGULATORY T LYMPHOCYTE; SECRETION (PROCESS); TH1 CELL;

CD40; DEC-205; PERIPHERAL TOLERANCE; TYPE 1 DIABETES;

ANIMALS; ANTIBODIES; ANTIGENS; ANTIGENS, CD40; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; DENDRITIC CELLS; DIABETES MELLITUS, EXPERIMENTAL; FORKHEAD TRANSCRIPTION FACTORS; IMMUNE TOLERANCE; INTERFERON-GAMMA; LIGANDS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED NOD; PEPTIDES; PHENOTYPE; T-LYMPHOCYTES, REGULATORY; TH1 CELLS; TOLL-LIKE RECEPTORS;

EID: 84897025305     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.0113013     Document Type: Article

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