Cigarette smoke-induced alveolar epithelial-mesenchymal transition is mediated by Rac1 activation

Biochimica et Biophysica Acta - General Subjects

Volumn 1840, Issue 6, 2014, Pages 1838-1849

  Shen, Hui Juan ^a   Sun, Yan Hong ^a   Zhang, Shui Juan ^b   Jiang, Jun Xia ^a   Dong, Xin Wei ^a   Jia, Yong Liang ^a   Shen, Jian ^a   Guan, Yan ^a   Zhang, Lin Hui ^a   Li, Fen Fen ^a   Lin, Xi Xi ^a   Wu, Xi Mei ^a   Xie, Qiang Min ^a   Yan, Xiao Feng ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

Author keywords

Cigarette smoke extract; Epithelial mesenchymal transition; Pulmonary fibrosis; Rac1; TGF 1

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; GELATINASE A; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAC1 PROTEIN; SMAD PROTEIN; SMAD2 PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA1; UVOMORULIN; VIMENTIN; CELL MARKER; CIGARETTE SMOKE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; DRUG ACTIVITY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REPRESSION; EPITHELIAL MESENCHYMAL TRANSITION; EXPOSURE; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS EPITHELIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; SMOKING; ANIMAL EXPERIMENT; CYTOKINE RELEASE; LUNG ALVEOLUS CELL; PHARMACOLOGICAL BLOCKING;

CIGARETTE SMOKE EXTRACT; EPITHELIAL-MESENCHYMAL TRANSITION; PULMONARY FIBROSIS; RAC1; TGF-Β1;

ANIMALS; EPITHELIAL-MESENCHYMAL TRANSITION; MICE; MICE, INBRED C57BL; NEUROPEPTIDES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PULMONARY ALVEOLI; RAC1 GTP-BINDING PROTEIN; SMAD2 PROTEIN; SMOKE; TOBACCO; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84897004237     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2014.01.033     Document Type: Article

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