Elucidating substrate promiscuity in the human cytochrome 3A4

Journal of Chemical Information and Modeling

Volumn 54, Issue 3, 2014, Pages 857-869

  Hayes, Christina ^a   Ansbro, Daniel ^a   Kontoyianni, Maria ^a  

^a SOUTHERN ILLINOIS UNIVERSITY EDWARDSVILLE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CRYSTALS; ENZYMES; LIGANDS; METABOLISM;

DOCKING ALGORITHMS; ENZYME CONFORMATIONS; FAVORABLE INTERACTIONS; METABOLIC REACTIONS; MOLECULAR PROPERTIES; MULTIPLE RECEPTORS; OXIDATIVE REACTION; SCORING FUNCTIONS;

SUBSTRATES;

CYP3A4 PROTEIN, HUMAN; CYTOCHROME P450 3A; DRUG; LIGAND;

BINDING SITE; CHEMISTRY; DRUG DEVELOPMENT; ENZYME SPECIFICITY; HUMAN; METABOLISM; MOLECULAR DOCKING;

BINDING SITES; CYTOCHROME P-450 CYP3A; DRUG DISCOVERY; HUMANS; LIGANDS; MOLECULAR DOCKING SIMULATION; PHARMACEUTICAL PREPARATIONS; SUBSTRATE SPECIFICITY;

EID: 84896986979     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci4006782     Document Type: Article

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