Development of accessible peptidic tool compounds to study the phosphatase PTP1B in intact cells

ACS Chemical Biology

Volumn 9, Issue 3, 2014, Pages 769-776

  Meyer, Christoph ^a   Hoeger, Birgit ^a   Temmerman, Koen ^b   Tatarek Nossol, Marianna ^c   Pogenberg, Vivian ^b   Bernhagen, Jürgen ^c   Wilmanns, Matthias ^b   Kapurniotu, Aphrodite ^d   Köhn, Maja ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^c RWTH AACHEN UNIVERSITY   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; INSULIN RECEPTOR; PROTEIN TYROSINE PHOSPHATASE 1B; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; CELL PENETRATING PEPTIDE; CSK TYROSINE-PROTEIN KINASE; ENZYME INHIBITOR; PEPTIDE; POLYARGININE; PROTEIN BINDING; PROTEIN TYROSINE KINASE; PTPN1 PROTEIN, HUMAN;

ACTIVE TRANSPORT; AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BREAST CANCER; CANCER CELL; CELL LYSATE; CELL PROLIFERATION ASSAY; CELLS; CELLULAR DISTRIBUTION; CYTOTOXICITY; DEGRADATION; DEPHOSPHORYLATION; DIABETES MELLITUS; ENDOCYTOSIS; ENDOPLASMIC RETICULUM; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME STRUCTURE; HUMAN; HYDROGEN BOND; IC 50; IN VITRO STUDY; INTACT CELL; MALIGNANT NEOPLASTIC DISEASE; OBESITY; ONCOGENE SRC; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; BINDING SITE; BIOLOGY; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; ENZYME SPECIFICITY; FLUORESCENCE POLARIZATION; MOLECULAR GENETICS; PROCEDURES; TOXICITY; TUMOR CELL LINE; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; BINDING SITES; CELL LINE, TUMOR; CELL PROLIFERATION; CELL-PENETRATING PEPTIDES; COMPUTATIONAL BIOLOGY; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; FLUORESCENCE POLARIZATION; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN BINDING; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; SRC-FAMILY KINASES; SUBSTRATE SPECIFICITY;

EID: 84896958284     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb400903u     Document Type: Article

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