-
1
-
-
78649516124
-
Functions of T cells in asthma: more than just T(H)2 cells
-
Lloyd, C. M. and Hessel, E. M., Functions of T cells in asthma: more than just T(H)2 cells. Nat. Rev. Immunol. 2010. 10: 838-848.
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 838-848
-
-
Lloyd, C.M.1
Hessel, E.M.2
-
2
-
-
0028260378
-
Attenuation of allergic airway inflammation in IL-4 deficient mice
-
Brusselle, G. G., Kips, J. C., Tavernier, J., Van Der Heyden, J. G., Cuvelier, C. A., Pauwels, R. A. and Bluethmann, H., Attenuation of allergic airway inflammation in IL-4 deficient mice. Clin. Exp. Allergy 1994. 24: 73-80.
-
(1994)
Clin. Exp. Allergy
, vol.24
, pp. 73-80
-
-
Brusselle, G.G.1
Kips, J.C.2
Tavernier, J.3
Van Der Heyden, J.G.4
Cuvelier, C.A.5
Pauwels, R.A.6
Bluethmann, H.7
-
3
-
-
0032545213
-
Interleukin-13: central mediator of allergic asthma
-
Wills-Karp, M., Luyimbazi, J, Xu, X., Schofield, B., Neben, T. Y., Karp, C. L. and Donaldson, D. D., Interleukin-13: central mediator of allergic asthma. Science 1998. 282: 2258-2261.
-
(1998)
Science
, vol.282
, pp. 2258-2261
-
-
Wills-Karp, M.1
Luyimbazi, J.2
Xu, X.3
Schofield, B.4
Neben, T.Y.5
Karp, C.L.6
Donaldson, D.D.7
-
4
-
-
0034235875
-
Integrated signals between IL-13, IL-4, and IL-5 regulate airways hyperreactivity
-
Webb, D. C., McKenzie, A. N., Koskinen, A. M., Yang, M., Mattes, J. and Foster, P. S., Integrated signals between IL-13, IL-4, and IL-5 regulate airways hyperreactivity. J. Immunol. 2000. 165: 108-113.
-
(2000)
J. Immunol.
, vol.165
, pp. 108-113
-
-
Webb, D.C.1
McKenzie, A.N.2
Koskinen, A.M.3
Yang, M.4
Mattes, J.5
Foster, P.S.6
-
5
-
-
4544274172
-
A critical role for eosinophils in allergic airways remodeling
-
Humbles, A. A., Lloyd, C. M., McMillan, S. J., Friend, D. S., Xanthou, G., McKenna, E. E., Ghiran, S. et al., A critical role for eosinophils in allergic airways remodeling. Science 2004. 305: 1776-1779.
-
(2004)
Science
, vol.305
, pp. 1776-1779
-
-
Humbles, A.A.1
Lloyd, C.M.2
McMillan, S.J.3
Friend, D.S.4
Xanthou, G.5
McKenna, E.E.6
Ghiran, S.7
-
6
-
-
0030689729
-
Induction of airway mucus production By T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production
-
Cohn, L., Homer, R. J., Marinov, A., Rankin, J. and Bottomly, K., Induction of airway mucus production By T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production. J. Exp. Med. 1997. 186: 1737-1747.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1737-1747
-
-
Cohn, L.1
Homer, R.J.2
Marinov, A.3
Rankin, J.4
Bottomly, K.5
-
7
-
-
77953795713
-
Pulmonary IL-17E (IL-25) production and IL-17RB+ myeloid cell-derived Th2 cytokine production are dependent upon stem cell factor-induced responses during chronic allergic pulmonary disease
-
Dolgachev, V., Petersen, B. C., Budelsky, A. L., Berlin, A. A. and Lukacs, N. W., Pulmonary IL-17E (IL-25) production and IL-17RB+ myeloid cell-derived Th2 cytokine production are dependent upon stem cell factor-induced responses during chronic allergic pulmonary disease. J. Immunol. 2009. 183: 5705-5715.
-
(2009)
J. Immunol.
, vol.183
, pp. 5705-5715
-
-
Dolgachev, V.1
Petersen, B.C.2
Budelsky, A.L.3
Berlin, A.A.4
Lukacs, N.W.5
-
8
-
-
77957745031
-
Inflammatory dendritic cells-not basophils-are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen
-
Hammad, H., Plantinga, M., Deswarte, K., Pouliot, P., Willart, M. A., Kool, M., Muskens, F. et al., Inflammatory dendritic cells-not basophils-are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen. J. Exp. Med. 2010. 207: 2097-2111.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 2097-2111
-
-
Hammad, H.1
Plantinga, M.2
Deswarte, K.3
Pouliot, P.4
Willart, M.A.5
Kool, M.6
Muskens, F.7
-
9
-
-
84455202426
-
Innate IL-13-producing nuocytes arise during allergic lung inflammation and contribute to airways hyperreactivity
-
and, e191-194.
-
Barlow, J. L., Bellosi, A., Hardman, C. S., Drynan, L. F., Wong, S. H., Cruickshank, J. P. and McKenzie, A. N., Innate IL-13-producing nuocytes arise during allergic lung inflammation and contribute to airways hyperreactivity. J. Allergy Clin. Immunol. 2012. 129: 191-198 e191-194.
-
(2012)
J. Allergy Clin. Immunol.
, vol.129
, pp. 191-198
-
-
Barlow, J.L.1
Bellosi, A.2
Hardman, C.S.3
Drynan, L.F.4
Wong, S.H.5
Cruickshank, J.P.6
McKenzie, A.N.7
-
10
-
-
35649028488
-
Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids
-
Woodruff, P. G., Boushey, H. A., Dolganov, G. M., Barker, C. S., Yang, Y. H., Donnelly, S., Ellwanger, A. et al., Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids. Proc. Natl. Acad. Sci. USA 2007. 104: 15858-15863.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 15858-15863
-
-
Woodruff, P.G.1
Boushey, H.A.2
Dolganov, G.M.3
Barker, C.S.4
Yang, Y.H.5
Donnelly, S.6
Ellwanger, A.7
-
11
-
-
69249150516
-
T-helper type 2-driven inflammation defines major subphenotypes of asthma
-
Woodruff, P. G., Modrek, B., Choy, D. F., Jia, G., Abbas, A. R., Ellwanger, A., Koth, L. L. et al., T-helper type 2-driven inflammation defines major subphenotypes of asthma. Am. J. Respir. Crit. Care Med. 2009. 180: 388-395.
-
(2009)
Am. J. Respir. Crit. Care Med.
, vol.180
, pp. 388-395
-
-
Woodruff, P.G.1
Modrek, B.2
Choy, D.F.3
Jia, G.4
Abbas, A.R.5
Ellwanger, A.6
Koth, L.L.7
-
12
-
-
61849155730
-
Mepolizumab for prednisone-dependent asthma with sputum eosinophilia
-
Nair, P., Pizzichini, M. M., Kjarsgaard, M., Inman, M. D., Efthimiadis, A., Pizzichini, E., Hargreave, F. E. et al., Mepolizumab for prednisone-dependent asthma with sputum eosinophilia. N. Engl. J. Med. 2009. 360: 985-993.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 985-993
-
-
Nair, P.1
Pizzichini, M.M.2
Kjarsgaard, M.3
Inman, M.D.4
Efthimiadis, A.5
Pizzichini, E.6
Hargreave, F.E.7
-
13
-
-
61849086181
-
Mepolizumab and exacerbations of refractory eosinophilic asthma
-
Haldar, P., Brightling, C. E., Hargadon, B., Gupta, S., Monteiro, W., Sousa, A., Marshall, R. P. et al., Mepolizumab and exacerbations of refractory eosinophilic asthma. N. Engl. J. Med. 2009. 360: 973-984.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 973-984
-
-
Haldar, P.1
Brightling, C.E.2
Hargadon, B.3
Gupta, S.4
Monteiro, W.5
Sousa, A.6
Marshall, R.P.7
-
14
-
-
78149326083
-
A novel subset of CD4(+) T(H)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma
-
Wang, Y. H., Voo, K. S., Liu, B., Chen, C. Y., Uygungil, B., Spoede, W., Bernstein, J. A. et al., A novel subset of CD4(+) T(H)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma. J. Exp. Med. 2010. 207: 2479-2491.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 2479-2491
-
-
Wang, Y.H.1
Voo, K.S.2
Liu, B.3
Chen, C.Y.4
Uygungil, B.5
Spoede, W.6
Bernstein, J.A.7
-
15
-
-
77950261975
-
How are T(H)2-type immune responses initiated and amplified?
-
Paul, W. E. and Zhu, J., How are T(H)2-type immune responses initiated and amplified? Nat. Rev. Immunol. 2010. 10: 225-235.
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 225-235
-
-
Paul, W.E.1
Zhu, J.2
-
16
-
-
84860342111
-
Type 2 innate lymphoid cells-new members of the "type 2 franchise" that mediate allergic airway inflammation
-
Mjosberg, J. and Spits, H., Type 2 innate lymphoid cells-new members of the "type 2 franchise" that mediate allergic airway inflammation. Eur. J. Immunol. 2012. 42: 1093-1096.
-
(2012)
Eur. J. Immunol.
, vol.42
, pp. 1093-1096
-
-
Mjosberg, J.1
Spits, H.2
-
17
-
-
84860343753
-
Pulmonary innate lymphoid cells are major producers of IL-5 and IL-13 in murine models of allergic asthma
-
Klein Wolterink, R. G., Kleinjan, A., van Nimwegen, M., Bergen, I., de Bruijn, M., Levani, Y. and Hendriks, R. W., Pulmonary innate lymphoid cells are major producers of IL-5 and IL-13 in murine models of allergic asthma. Eur. J. Immunol. 2012. 42: 1106-1116.
-
(2012)
Eur. J. Immunol.
, vol.42
, pp. 1106-1116
-
-
Klein Wolterink, R.G.1
Kleinjan, A.2
van Nimwegen, M.3
Bergen, I.4
de Bruijn, M.5
Levani, Y.6
Hendriks, R.W.7
-
18
-
-
44849117539
-
Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system
-
Kondo, Y., Yoshimoto, T., Yasuda, K., Futatsugi-Yumikura, S., Morimoto, M., Hayashi, N., Hoshino, T. et al., Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system. Int. Immunol. 2008. 20: 791-800.
-
(2008)
Int. Immunol.
, vol.20
, pp. 791-800
-
-
Kondo, Y.1
Yoshimoto, T.2
Yasuda, K.3
Futatsugi-Yumikura, S.4
Morimoto, M.5
Hayashi, N.6
Hoshino, T.7
-
19
-
-
79959380307
-
Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity
-
Chang, Y. J., Kim, H. Y., Albacker, L. A., Baumgarth, N., McKenzie, A. N., Smith, D. E., Dekruyff, R. H. et al., Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity. Nat. Immunol. 2011. 12: 631-638.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 631-638
-
-
Chang, Y.J.1
Kim, H.Y.2
Albacker, L.A.3
Baumgarth, N.4
McKenzie, A.N.5
Smith, D.E.6
Dekruyff, R.H.7
-
20
-
-
84863011729
-
IL-33-responsive lineage- CD25+ CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs
-
Bartemes, K. R., Iijima, K., Kobayashi, T., Kephart, G. M., McKenzie, A. N. and Kita, H., IL-33-responsive lineage- CD25+ CD44(hi) lymphoid cells mediate innate type 2 immunity and allergic inflammation in the lungs. J. Immunol. 2012. 188: 1503-1513.
-
(2012)
J. Immunol.
, vol.188
, pp. 1503-1513
-
-
Bartemes, K.R.1
Iijima, K.2
Kobayashi, T.3
Kephart, G.M.4
McKenzie, A.N.5
Kita, H.6
-
21
-
-
84455169459
-
Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity
-
e211-216.
-
Kim, H. Y., Chang, Y. J., Subramanian, S., Lee, H. H., Albacker, L. A., Matangkasombut, P., Savage, P. B. et al., Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity. J. Allergy Clin. Immunol. 2012. 129: 216-227 e211-216.
-
(2012)
J. Allergy Clin. Immunol.
, vol.129
, pp. 216-227
-
-
Kim, H.Y.1
Chang, Y.J.2
Subramanian, S.3
Lee, H.H.4
Albacker, L.A.5
Matangkasombut, P.6
Savage, P.B.7
-
22
-
-
84858775590
-
Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation
-
Halim, T. Y., Krauss, R. H., Sun, A. C. and Takei, F., Lung natural helper cells are a critical source of Th2 cell-type cytokines in protease allergen-induced airway inflammation. Immunity 2012. 36: 451-463.
-
(2012)
Immunity
, vol.36
, pp. 451-463
-
-
Halim, T.Y.1
Krauss, R.H.2
Sun, A.C.3
Takei, F.4
-
23
-
-
80054927155
-
An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation
-
Wilhelm, C., Hirota, K., Stieglitz, B., Van Snick, J., Tolaini, M., Lahl, K., Sparwasser, T. et al., An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation. Nat. Immunol. 2011. 12: 1071-1077.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 1071-1077
-
-
Wilhelm, C.1
Hirota, K.2
Stieglitz, B.3
Van Snick, J.4
Tolaini, M.5
Lahl, K.6
Sparwasser, T.7
-
24
-
-
84867773093
-
The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells
-
Mjosberg, J., Bernink, J., Golebski, K., Karrich, J. J., Peters, C. P., Blom, B., Te Velde, A. A. et al., The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells. Immunity 2012. 37: 649-659.
-
(2012)
Immunity
, vol.37
, pp. 649-659
-
-
Mjosberg, J.1
Bernink, J.2
Golebski, K.3
Karrich, J.J.4
Peters, C.P.5
Blom, B.6
Te Velde, A.A.7
-
25
-
-
84867769688
-
The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells
-
Hoyler, T., Klose, C. S., Souabni, A., Turqueti-Neves, A., Pfeifer, D., Rawlins, E. L., Voehringer, D. et al., The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells. Immunity 2012. 37: 634-648.
-
(2012)
Immunity
, vol.37
, pp. 634-648
-
-
Hoyler, T.1
Klose, C.S.2
Souabni, A.3
Turqueti-Neves, A.4
Pfeifer, D.5
Rawlins, E.L.6
Voehringer, D.7
-
26
-
-
84863393407
-
Transcription factor RORalpha is critical for nuocyte development
-
Wong, S. H., Walker, J. A., Jolin, H. E., Drynan, L. F., Hams, E., Camelo, A., Barlow, J. L. et al., Transcription factor RORalpha is critical for nuocyte development. Nat. Immunol. 2012. 13: 229-236.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 229-236
-
-
Wong, S.H.1
Walker, J.A.2
Jolin, H.E.3
Drynan, L.F.4
Hams, E.5
Camelo, A.6
Barlow, J.L.7
-
27
-
-
84866519013
-
Retinoic-acid-receptor-related orphan nuclear receptor alpha is required for natural helper cell development and allergic inflammation
-
Halim, T. Y., MacLaren, A., Romanish, M. T., Gold, M. J., McNagny, K. M. and Takei, F., Retinoic-acid-receptor-related orphan nuclear receptor alpha is required for natural helper cell development and allergic inflammation. Immunity 2012. 37: 463-474.
-
(2012)
Immunity
, vol.37
, pp. 463-474
-
-
Halim, T.Y.1
MacLaren, A.2
Romanish, M.T.3
Gold, M.J.4
McNagny, K.M.5
Takei, F.6
-
28
-
-
84879311467
-
An essential, dose-dependent role for the transcription factor GATA-3 in the development of IL-5+ and IL-13+ type 2 innate lymphoid cells
-
Klein Wolterink, R. G., Serafini, N., van Nimwegen, M., Vosshenrich, C. A., Fonseca-Pereira, D., Veiga-Fernandes, H., Hendriks, R. W. et al., An essential, dose-dependent role for the transcription factor GATA-3 in the development of IL-5+ and IL-13+ type 2 innate lymphoid cells. Proc. Natl. Acad. Sci. USA 2013. 110: 10240-10245.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 10240-10245
-
-
Klein Wolterink, R.G.1
Serafini, N.2
van Nimwegen, M.3
Vosshenrich, C.A.4
Fonseca-Pereira, D.5
Veiga-Fernandes, H.6
Hendriks, R.W.7
-
29
-
-
84867164026
-
STAT6 regulates natural helper cell proliferation during lung inflammation initiated by Alternaria
-
Doherty, T. A., Khorram, N., Chang, J. E., Kim, H. K., Rosenthal, P., Croft, M. and Broide, D. H., STAT6 regulates natural helper cell proliferation during lung inflammation initiated by Alternaria. Am. J. Physiol. Lung Cell Mol. Physiol. 2012. 303: L577-L588.
-
(2012)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.303
-
-
Doherty, T.A.1
Khorram, N.2
Chang, J.E.3
Kim, H.K.4
Rosenthal, P.5
Croft, M.6
Broide, D.H.7
-
30
-
-
84876008998
-
Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma
-
Barnig, C., Cernadas, M., Dutile, S., Liu, X., Perrella, M. A., Kazani, S., Wechsler, M. E. et al., Lipoxin A4 regulates natural killer cell and type 2 innate lymphoid cell activation in asthma. Sci. Transl. Med. 2013. 5: 174ra126.
-
(2013)
Sci. Transl. Med.
, vol.5
-
-
Barnig, C.1
Cernadas, M.2
Dutile, S.3
Liu, X.4
Perrella, M.A.5
Kazani, S.6
Wechsler, M.E.7
-
31
-
-
84860691114
-
The airway epithelium in asthma
-
Lambrecht, B. N. and Hammad, H., The airway epithelium in asthma. Nat. Med. 2012. 18: 684-692.
-
(2012)
Nat. Med.
, vol.18
, pp. 684-692
-
-
Lambrecht, B.N.1
Hammad, H.2
-
32
-
-
67649216604
-
Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response
-
Sokol, C. L., Chu, N. Q., Yu, S., Nish, S. A., Laufer, T. M. and Medzhitov, R., Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response. Nat. Immunol. 2009. 10: 713-720.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 713-720
-
-
Sokol, C.L.1
Chu, N.Q.2
Yu, S.3
Nish, S.A.4
Laufer, T.M.5
Medzhitov, R.6
-
33
-
-
0141989811
-
Airway eosinophils accumulate in the mediastinal lymph nodes but lack antigen-presenting potential for naive T cells
-
van Rijt, L. S., Vos, N., Hijdra, D., de Vries, V. C., Hoogsteden, H. C. and Lambrecht, B. N., Airway eosinophils accumulate in the mediastinal lymph nodes but lack antigen-presenting potential for naive T cells. J. Immunol. 2003. 171: 3372-3378.
-
(2003)
J. Immunol.
, vol.171
, pp. 3372-3378
-
-
van Rijt, L.S.1
Vos, N.2
Hijdra, D.3
de Vries, V.C.4
Hoogsteden, H.C.5
Lambrecht, B.N.6
-
34
-
-
84874254531
-
Conventional and monocyte-derived CD11b+ dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen
-
Plantinga, M., Guilliams, M., Vanheerswynghels, M., Deswarte, K., Branco Madeira, F., Toussaint, W., Vanhoutte, L. et al., Conventional and monocyte-derived CD11b+ dendritic cells initiate and maintain T helper 2 cell-mediated immunity to house dust mite allergen. Immunity 2013. 38: 322-335.
-
(2013)
Immunity
, vol.38
, pp. 322-335
-
-
Plantinga, M.1
Guilliams, M.2
Vanheerswynghels, M.3
Deswarte, K.4
Branco Madeira, F.5
Toussaint, W.6
Vanhoutte, L.7
-
35
-
-
84859404292
-
Lung dendritic cells in respiratory viral infection and asthma : from protection to immunopathology
-
Lambrecht, B. N. and Hammad, H., Lung dendritic cells in respiratory viral infection and asthma : from protection to immunopathology. Ann. Rev. Immunol. 2012. 30: 243-270.
-
(2012)
Ann. Rev. Immunol.
, vol.30
, pp. 243-270
-
-
Lambrecht, B.N.1
Hammad, H.2
-
36
-
-
83655181164
-
Pulmonary CD103(+) dendritic cells prime Th2 responses to inhaled allergens
-
Nakano, H., Free, M. E., Whitehead, G. S., Maruoka, S., Wilson, R. H., Nakano, K. and Cook, D. N., Pulmonary CD103(+) dendritic cells prime Th2 responses to inhaled allergens. Mucosal Immunol. 2012. 5: 53-65.
-
(2012)
Mucosal Immunol.
, vol.5
, pp. 53-65
-
-
Nakano, H.1
Free, M.E.2
Whitehead, G.S.3
Maruoka, S.4
Wilson, R.H.5
Nakano, K.6
Cook, D.N.7
-
37
-
-
84871803451
-
Resident CD11b(+)Ly6C(-) lung dendritic cells are responsible for allergic airway sensitization to house dust mite in mice
-
Mesnil, C., Sabatel, C. M., Marichal, T., Toussaint, M., Cataldo, D., Drion, P. V., Lekeux, P. et al., Resident CD11b(+)Ly6C(-) lung dendritic cells are responsible for allergic airway sensitization to house dust mite in mice. PLoS One 2012. 7: e53242.
-
(2012)
PLoS One
, vol.7
-
-
Mesnil, C.1
Sabatel, C.M.2
Marichal, T.3
Toussaint, M.4
Cataldo, D.5
Drion, P.V.6
Lekeux, P.7
-
38
-
-
70049103105
-
An anti-inflammatory role for plasmacytoid dendritic cells in allergic airway inflammation
-
Kool, M., van Nimwegen, M., Willart, M. A., Muskens, F., Boon, L., Smit, J. J., Coyle, A. et al., An anti-inflammatory role for plasmacytoid dendritic cells in allergic airway inflammation. J. Immunol. 2009. 183: 1074-1082.
-
(2009)
J. Immunol.
, vol.183
, pp. 1074-1082
-
-
Kool, M.1
van Nimwegen, M.2
Willart, M.A.3
Muskens, F.4
Boon, L.5
Smit, J.J.6
Coyle, A.7
-
39
-
-
3142720367
-
Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen
-
de Heer, H. J., Hammad, H., Soullie, T., Hijdra, D., Vos, N., Willart, M. A., Hoogsteden, H. C. et al., Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen. J. Exp. Med. 2004. 200: 89-98.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 89-98
-
-
de Heer, H.J.1
Hammad, H.2
Soullie, T.3
Hijdra, D.4
Vos, N.5
Willart, M.A.6
Hoogsteden, H.C.7
-
40
-
-
64149087970
-
House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells
-
Hammad, H., Chieppa, M., Perros, F., Willart, M. A., Germain, R. N. and Lambrecht, B. N., House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells. Nat. Med. 2009. 15: 410-416.
-
(2009)
Nat. Med.
, vol.15
, pp. 410-416
-
-
Hammad, H.1
Chieppa, M.2
Perros, F.3
Willart, M.A.4
Germain, R.N.5
Lambrecht, B.N.6
-
41
-
-
84866130874
-
Interleukin-1alpha controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33
-
Willart, M. A., Deswarte, K., Pouliot, P., Braun, H., Beyaert, R., Lambrecht, B. N. and Hammad, H., Interleukin-1alpha controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33. J. Exp. Med. 2012. 209: 1505-1517.
-
(2012)
J. Exp. Med.
, vol.209
, pp. 1505-1517
-
-
Willart, M.A.1
Deswarte, K.2
Pouliot, P.3
Braun, H.4
Beyaert, R.5
Lambrecht, B.N.6
Hammad, H.7
-
42
-
-
65649101936
-
Toll/IL-1 signaling is critical for house dust mite-specific Th1 and Th2 responses
-
Phipps, S., Lam, C. E., Kaiko, G. E., Foo, S. Y., Collison, A., Mattes, J., Barry, J. et al., Toll/IL-1 signaling is critical for house dust mite-specific Th1 and Th2 responses. Am. J. Respir. Crit. Care Med. 2009. 179: 883-893.
-
(2009)
Am. J. Respir. Crit. Care Med.
, vol.179
, pp. 883-893
-
-
Phipps, S.1
Lam, C.E.2
Kaiko, G.E.3
Foo, S.Y.4
Collison, A.5
Mattes, J.6
Barry, J.7
-
43
-
-
79954597670
-
An unexpected role for uric acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma
-
Kool, M., Willart, M. A., van Nimwegen, M., Bergen, I., Pouliot, P., Virchow, J. C., Rogers, N. et al., An unexpected role for uric acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma. Immunity 2011. 34: 527-540.
-
(2011)
Immunity
, vol.34
, pp. 527-540
-
-
Kool, M.1
Willart, M.A.2
van Nimwegen, M.3
Bergen, I.4
Pouliot, P.5
Virchow, J.C.6
Rogers, N.7
-
44
-
-
34548713042
-
TLR3- and Th2 cytokine-dependent production of thymic stromal lymphopoietin in human airway epithelial cells
-
Kato, A., Favoreto, S., Jr., Avila, P. C. and Schleimer, R. P., TLR3- and Th2 cytokine-dependent production of thymic stromal lymphopoietin in human airway epithelial cells. J. Immunol. 2007. 179: 1080-1087.
-
(2007)
J. Immunol.
, vol.179
, pp. 1080-1087
-
-
Kato, A.1
Favoreto Jr., S.2
Avila, P.C.3
Schleimer, R.P.4
-
45
-
-
33749685728
-
IL-1 Receptor antagonist as a positional candidate gene in a murine model of allergic asthma
-
Ramadas, R. A., Li, X., Shubitowski, D. M., Samineni, S., Wills-Karp, M. and Ewart, S. L., IL-1 Receptor antagonist as a positional candidate gene in a murine model of allergic asthma. Immunogenetics 2006. 58: 851-855.
-
(2006)
Immunogenetics
, vol.58
, pp. 851-855
-
-
Ramadas, R.A.1
Li, X.2
Shubitowski, D.M.3
Samineni, S.4
Wills-Karp, M.5
Ewart, S.L.6
-
46
-
-
77954517684
-
Dual role of interleukin-1alpha in delayed-type hypersensitivity and airway hyperresponsiveness
-
Caucig, P., Teschner, D., Dinges, S., Maxeiner, J. H., Reuter, S., Finotto, S., Taube, C. et al., Dual role of interleukin-1alpha in delayed-type hypersensitivity and airway hyperresponsiveness. Int. Arch. Allergy Immunol. 2010. 152: 303-312.
-
(2010)
Int. Arch. Allergy Immunol.
, vol.152
, pp. 303-312
-
-
Caucig, P.1
Teschner, D.2
Dinges, S.3
Maxeiner, J.H.4
Reuter, S.5
Finotto, S.6
Taube, C.7
-
47
-
-
0038744514
-
The IL-1 receptor 1 is critical for Th2 cell type airway immune responses in a mild but not in a more severe asthma model
-
Schmitz, N., Kurrer, M. and Kopf, M., The IL-1 receptor 1 is critical for Th2 cell type airway immune responses in a mild but not in a more severe asthma model. Eur. J. Immunol. 2003. 33: 991-1000.
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 991-1000
-
-
Schmitz, N.1
Kurrer, M.2
Kopf, M.3
-
48
-
-
84863263746
-
Analysis of NLRP3 in the development of allergic airway disease in mice
-
Allen, I. C., Jania, C. M., Wilson, J. E., Tekeppe, E. M., Hua, X., Brickey, W. J., Kwan, M. et al., Analysis of NLRP3 in the development of allergic airway disease in mice. J. Immunol. 2012. 188: 2884-2893.
-
(2012)
J. Immunol.
, vol.188
, pp. 2884-2893
-
-
Allen, I.C.1
Jania, C.M.2
Wilson, J.E.3
Tekeppe, E.M.4
Hua, X.5
Brickey, W.J.6
Kwan, M.7
-
49
-
-
45749111446
-
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
-
Eisenbarth, S. C., Colegio, O. R., O'Connor, W., Sutterwala, F. S. and Flavell, R. A., Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature 2008. 453: 1122-1126.
-
(2008)
Nature
, vol.453
, pp. 1122-1126
-
-
Eisenbarth, S.C.1
Colegio, O.R.2
O'Connor, W.3
Sutterwala, F.S.4
Flavell, R.A.5
-
50
-
-
75549085516
-
IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation
-
Kurowska-Stolarska, M., Stolarski, B., Kewin, P., Murphy, G., Corrigan, C. J., Ying, S., Pitman, N. et al., IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation. J. Immunol. 2009. 183: 6469-6477.
-
(2009)
J. Immunol.
, vol.183
, pp. 6469-6477
-
-
Kurowska-Stolarska, M.1
Stolarski, B.2
Kewin, P.3
Murphy, G.4
Corrigan, C.J.5
Ying, S.6
Pitman, N.7
-
51
-
-
77957113600
-
A large-scale, consortium-based genomewide association study of asthma
-
Moffatt, M. F., Gut, I. G., Demenais, F., Strachan, D. P., Bouzigon, E., Heath, S., von Mutius, E. et al., A large-scale, consortium-based genomewide association study of asthma. N. Engl. J. Med. 2010. 363: 1211-1221.
-
(2010)
N. Engl. J. Med.
, vol.363
, pp. 1211-1221
-
-
Moffatt, M.F.1
Gut, I.G.2
Demenais, F.3
Strachan, D.P.4
Bouzigon, E.5
Heath, S.6
von Mutius, E.7
-
52
-
-
84871719326
-
IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization
-
Chu, D. K., Llop-Guevara, A., Walker, T. D., Flader, K., Goncharova, S., Boudreau, J. E., Moore, C. L. et al., IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization. J. Allergy Clin. Immunol. 2012. 131: 187-200.
-
(2012)
J. Allergy Clin. Immunol.
, vol.131
, pp. 187-200
-
-
Chu, D.K.1
Llop-Guevara, A.2
Walker, T.D.3
Flader, K.4
Goncharova, S.5
Boudreau, J.E.6
Moore, C.L.7
-
53
-
-
84860357324
-
Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection
-
Wills-Karp, M., Rani, R., Dienger, K., Lewkowich, I., Fox, J. G., Perkins, C., Lewis, L. et al., Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection. J. Exp. Med. 2012. 209: 607-622.
-
(2012)
J. Exp. Med.
, vol.209
, pp. 607-622
-
-
Wills-Karp, M.1
Rani, R.2
Dienger, K.3
Lewkowich, I.4
Fox, J.G.5
Perkins, C.6
Lewis, L.7
-
54
-
-
79957571971
-
IL-33-activated dendritic cells are critical for allergic airway inflammation
-
Besnard, A. G., Togbe, D., Guillou, N., Erard, F., Quesniaux, V. and Ryffel, B., IL-33-activated dendritic cells are critical for allergic airway inflammation. Eur. J. Immunol. 2011. 41: 1675-1686.
-
(2011)
Eur. J. Immunol.
, vol.41
, pp. 1675-1686
-
-
Besnard, A.G.1
Togbe, D.2
Guillou, N.3
Erard, F.4
Quesniaux, V.5
Ryffel, B.6
-
55
-
-
0033855772
-
Myeloid dendritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation
-
Lambrecht, B. N., De Veerman, M., Coyle, A. J., Gutierrez-Ramos, J. C., Thielemans, K. and Pauwels, R. A., Myeloid dendritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation. J. Clin. Invest. 2000. 106: 551-559.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 551-559
-
-
Lambrecht, B.N.1
De Veerman, M.2
Coyle, A.J.3
Gutierrez-Ramos, J.C.4
Thielemans, K.5
Pauwels, R.A.6
-
56
-
-
70349337464
-
IL-33 activates unprimed murine basophils directly in vitro and induces their in vivo expansion indirectly by promoting hematopoietic growth factor production
-
Schneider, E., Petit-Bertron, A. F., Bricard, R., Levasseur, M., Ramadan, A., Girard, J. P., Herbelin, A. et al., IL-33 activates unprimed murine basophils directly in vitro and induces their in vivo expansion indirectly by promoting hematopoietic growth factor production. J. Immunol. 2009. 183: 3591-3597.
-
(2009)
J. Immunol.
, vol.183
, pp. 3591-3597
-
-
Schneider, E.1
Petit-Bertron, A.F.2
Bricard, R.3
Levasseur, M.4
Ramadan, A.5
Girard, J.P.6
Herbelin, A.7
-
57
-
-
79957537407
-
IL-33 links tissue cells, dendritic cells and Th2 cell development in a mouse model of asthma
-
Eiwegger, T. and Akdis, C. A., IL-33 links tissue cells, dendritic cells and Th2 cell development in a mouse model of asthma. Eur. J. Immunol. 2011. 41: 1535-1538.
-
(2011)
Eur. J. Immunol.
, vol.41
, pp. 1535-1538
-
-
Eiwegger, T.1
Akdis, C.A.2
-
58
-
-
84873747719
-
IL-33 citrine reporter mice reveal the temporal and spatial expression of IL-33 during allergic lung inflammation
-
Hardman, C. S., Panova, V. and McKenzie, A. N., IL-33 citrine reporter mice reveal the temporal and spatial expression of IL-33 during allergic lung inflammation. Eur. J. Immunol. 2012. 43: 488-498.
-
(2012)
Eur. J. Immunol.
, vol.43
, pp. 488-498
-
-
Hardman, C.S.1
Panova, V.2
McKenzie, A.N.3
-
59
-
-
68249137289
-
Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases
-
Luthi, A. U., Cullen, S. P., McNeela, E. A., Duriez, P. J., Afonina, I. S., Sheridan, C., Brumatti, G. et al., Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases. Immunity 2009. 31: 84-98.
-
(2009)
Immunity
, vol.31
, pp. 84-98
-
-
Luthi, A.U.1
Cullen, S.P.2
McNeela, E.A.3
Duriez, P.J.4
Afonina, I.S.5
Sheridan, C.6
Brumatti, G.7
-
60
-
-
84877147109
-
Death at the airway epithelium in asthma
-
Lambrecht, B. N. and Hammad, H., Death at the airway epithelium in asthma. Cell Res. 2013. 23: 588-589.
-
(2013)
Cell Res.
, vol.23
, pp. 588-589
-
-
Lambrecht, B.N.1
Hammad, H.2
-
61
-
-
84857134135
-
IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G
-
Lefrancais, E., Roga, S., Gautier, V., Gonzalez-de-Peredo, A., Monsarrat, B., Girard, J. P. and Cayrol, C., IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G. Proc. Natl. Acad. Sci. USA 2012. 109: 1673-1678.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 1673-1678
-
-
Lefrancais, E.1
Roga, S.2
Gautier, V.3
Gonzalez-de-Peredo, A.4
Monsarrat, B.5
Girard, J.P.6
Cayrol, C.7
-
62
-
-
84872930976
-
Apoptotic cell clearance by bronchial epithelial cells critically influences airway inflammation
-
Juncadella, I. J., Kadl, A., Sharma, A. K., Shim, Y. M., Hochreiter-Hufford, A., Borish, L. and Ravichandran, K. S., Apoptotic cell clearance by bronchial epithelial cells critically influences airway inflammation. Nature 2013. 493: 547-551.
-
(2013)
Nature
, vol.493
, pp. 547-551
-
-
Juncadella, I.J.1
Kadl, A.2
Sharma, A.K.3
Shim, Y.M.4
Hochreiter-Hufford, A.5
Borish, L.6
Ravichandran, K.S.7
-
63
-
-
84862636380
-
F-box protein FBXL19-mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammation
-
Zhao, J., Wei, J., Mialki, R. K., Mallampalli, D. F., Chen, B. B., Coon, T., Zou, C. et al., F-box protein FBXL19-mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammation. Nat. Immunol. 2012. 13: 651-658.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 651-658
-
-
Zhao, J.1
Wei, J.2
Mialki, R.K.3
Mallampalli, D.F.4
Chen, B.B.5
Coon, T.6
Zou, C.7
-
64
-
-
79959821549
-
Allergen-induced expression of IL-25 and IL-25 receptor in atopic asthmatic airways and late-phase cutaneous responses
-
Corrigan, C. J., Wang, W., Meng, Q., Fang, C., Eid, G., Caballero, M. R., Lv, Z. et al., Allergen-induced expression of IL-25 and IL-25 receptor in atopic asthmatic airways and late-phase cutaneous responses. J. Allergy Clin. Immunol. 2011. 128: 116-124.
-
(2011)
J. Allergy Clin. Immunol.
, vol.128
, pp. 116-124
-
-
Corrigan, C.J.1
Wang, W.2
Meng, Q.3
Fang, C.4
Eid, G.5
Caballero, M.R.6
Lv, Z.7
-
65
-
-
84866534540
-
Epithelial cell-derived IL-25, but not Th17 cell-derived IL-17 or IL-17F, is crucial for murine asthma
-
Suzukawa, M., Morita, H., Nambu, A., Arae, K., Shimura, E., Shibui, A., Yamaguchi, S. et al., Epithelial cell-derived IL-25, but not Th17 cell-derived IL-17 or IL-17F, is crucial for murine asthma. J. Immunol. 2012. 189: 3641-3652.
-
(2012)
J. Immunol.
, vol.189
, pp. 3641-3652
-
-
Suzukawa, M.1
Morita, H.2
Nambu, A.3
Arae, K.4
Shimura, E.5
Shibui, A.6
Yamaguchi, S.7
-
66
-
-
18244405108
-
IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo
-
Fort, M. M., Cheung, J., Yen, D., Li, J., Zurawski, S. M., Lo, S., Menon, S. et al., IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo. Immunity 2001. 15: 985-995.
-
(2001)
Immunity
, vol.15
, pp. 985-995
-
-
Fort, M.M.1
Cheung, J.2
Yen, D.3
Li, J.4
Zurawski, S.M.5
Lo, S.6
Menon, S.7
-
67
-
-
67349151366
-
Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma
-
Goswami, S., Angkasekwinai, P., Shan, M., Greenlee, K. J., Barranco, W. T., Polikepahad, S., Seryshev, A. et al., Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma. Nat. Immunol. 2009. 10: 496-503.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 496-503
-
-
Goswami, S.1
Angkasekwinai, P.2
Shan, M.3
Greenlee, K.J.4
Barranco, W.T.5
Polikepahad, S.6
Seryshev, A.7
-
68
-
-
34547820890
-
IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells
-
Wang, Y. H., Angkasekwinai, P., Lu, N., Voo, K. S., Arima, K., Hanabuchi, S., Hippe, A. et al., IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells. J. Exp. Med. 2007. 204: 1837-1847.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1837-1847
-
-
Wang, Y.H.1
Angkasekwinai, P.2
Lu, N.3
Voo, K.S.4
Arima, K.5
Hanabuchi, S.6
Hippe, A.7
-
69
-
-
34447281733
-
Interleukin 25 promotes the initiation of proallergic type 2 responses
-
Angkasekwinai, P., Park, H., Wang, Y. H., Wang, Y. H., Chang, S. H., Corry, D. B., Liu, Y. J. et al., Interleukin 25 promotes the initiation of proallergic type 2 responses. J. Exp. Med. 2007. 204: 1509-1517.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1509-1517
-
-
Angkasekwinai, P.1
Park, H.2
Wang, Y.H.3
Wang, Y.H.4
Chang, S.H.5
Corry, D.B.6
Liu, Y.J.7
-
70
-
-
78049508452
-
NK cell deficiency predisposes to viral-induced Th2-type allergic inflammation via epithelial-derived IL-25
-
Kaiko, G. E., Phipps, S., Angkasekwinai, P., Dong, C. and Foster, P. S., NK cell deficiency predisposes to viral-induced Th2-type allergic inflammation via epithelial-derived IL-25. J. Immunol. 2010. 185: 4681-4690.
-
(2010)
J. Immunol.
, vol.185
, pp. 4681-4690
-
-
Kaiko, G.E.1
Phipps, S.2
Angkasekwinai, P.3
Dong, C.4
Foster, P.S.5
-
71
-
-
76949102494
-
Regulation of IL-9 expression by IL-25 signaling
-
Angkasekwinai, P., Chang, S. H., Thapa, M., Watarai, H. and Dong, C., Regulation of IL-9 expression by IL-25 signaling. Nat. Immunol. 2010. 11: 250-256.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 250-256
-
-
Angkasekwinai, P.1
Chang, S.H.2
Thapa, M.3
Watarai, H.4
Dong, C.5
-
72
-
-
84860691693
-
Interleukin-25 induces type 2 cytokine production in a steroid-resistant interleukin-17RB+ myeloid population that exacerbates asthmatic pathology
-
Petersen, B. C., Budelsky, A. L., Baptist, A. P., Schaller, M. A. and Lukacs, N. W., Interleukin-25 induces type 2 cytokine production in a steroid-resistant interleukin-17RB+ myeloid population that exacerbates asthmatic pathology. Nat. Med. 2012. 18: 751-758.
-
(2012)
Nat. Med.
, vol.18
, pp. 751-758
-
-
Petersen, B.C.1
Budelsky, A.L.2
Baptist, A.P.3
Schaller, M.A.4
Lukacs, N.W.5
-
73
-
-
84871373164
-
IL-25 drives remodelling in allergic airways disease induced by house dust mite
-
Gregory, L. G., Jones, C. P., Walker, S. A., Sawant, D., Gowers, K. H., Campbell, G. A., McKenzie, A. N. et al., IL-25 drives remodelling in allergic airways disease induced by house dust mite. Thorax 2013. 68: 82-90.
-
(2013)
Thorax
, vol.68
, pp. 82-90
-
-
Gregory, L.G.1
Jones, C.P.2
Walker, S.A.3
Sawant, D.4
Gowers, K.H.5
Campbell, G.A.6
McKenzie, A.N.7
-
74
-
-
0032211803
-
GM-CSF transgene expression in the airway allows aerosolized ovalbumin to induce allergic sensitization in mice
-
Stampfli, M. R., Wiley, R. E., Scott Neigh, G., Gajewska, B. U., Lei, X. F., Snider, D. P., Xing, Z. et al., GM-CSF transgene expression in the airway allows aerosolized ovalbumin to induce allergic sensitization in mice. J. Clin. Invest. 1998. 102: 1704-1714.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 1704-1714
-
-
Stampfli, M.R.1
Wiley, R.E.2
Scott Neigh, G.3
Gajewska, B.U.4
Lei, X.F.5
Snider, D.P.6
Xing, Z.7
-
75
-
-
40449117731
-
The IL-3/IL-5/GM-CSF common receptor plays a pivotal role in the regulation of Th2 immunity and allergic airway inflammation
-
Asquith, K. L., Ramshaw, H. S., Hansbro, P. M., Beagley, K. W., Lopez, A. F. and Foster, P. S., The IL-3/IL-5/GM-CSF common receptor plays a pivotal role in the regulation of Th2 immunity and allergic airway inflammation. J. Immunol. 2008. 180: 1199-1206.
-
(2008)
J. Immunol.
, vol.180
, pp. 1199-1206
-
-
Asquith, K.L.1
Ramshaw, H.S.2
Hansbro, P.M.3
Beagley, K.W.4
Lopez, A.F.5
Foster, P.S.6
-
76
-
-
0036789513
-
Granulocyte macrophage colony-stimulating factor-driven respiratory mucosal sensitization induces Th2 differentiation and function independently of interleukin-4
-
Ritz, S. A., Cundall, M. J., Gajewska, B. U., Alvarez, D., Gutierrez-Ramos, J. C., Coyle, A. J., McKenzie, A. N. et al., Granulocyte macrophage colony-stimulating factor-driven respiratory mucosal sensitization induces Th2 differentiation and function independently of interleukin-4. Am. J. Respir. Cell Mol. Biol. 2002. 27: 428-435.
-
(2002)
Am. J. Respir. Cell Mol. Biol.
, vol.27
, pp. 428-435
-
-
Ritz, S.A.1
Cundall, M.J.2
Gajewska, B.U.3
Alvarez, D.4
Gutierrez-Ramos, J.C.5
Coyle, A.J.6
McKenzie, A.N.7
-
77
-
-
8444223053
-
Intranasal exposure of mice to house dust mite elicits allergic airway inflammation via a GM-CSF-mediated mechanism
-
Cates, E. C., Fattouh, R., Wattie, J., Inman, M. D., Goncharova, S., Coyle, A. J., Gutierrez-Ramos, J. C. et al., Intranasal exposure of mice to house dust mite elicits allergic airway inflammation via a GM-CSF-mediated mechanism. J. Immunol. 2004. 173: 6384-6392.
-
(2004)
J. Immunol.
, vol.173
, pp. 6384-6392
-
-
Cates, E.C.1
Fattouh, R.2
Wattie, J.3
Inman, M.D.4
Goncharova, S.5
Coyle, A.J.6
Gutierrez-Ramos, J.C.7
-
78
-
-
0032758733
-
Diesel exhaust particulate induces airway hyperresponsiveness in a murine model: essential role of GM-CSF
-
Ohta, K., Yamashita, N., Tajima, M., Miyasaka, T., Nakano, J., Nakajima, M., Ishii, A. et al., Diesel exhaust particulate induces airway hyperresponsiveness in a murine model: essential role of GM-CSF. J. Allergy Clin. Immunol. 1999. 104: 1024-1030.
-
(1999)
J. Allergy Clin. Immunol.
, vol.104
, pp. 1024-1030
-
-
Ohta, K.1
Yamashita, N.2
Tajima, M.3
Miyasaka, T.4
Nakano, J.5
Nakajima, M.6
Ishii, A.7
-
79
-
-
33744910083
-
Diesel exhaust particle-exposed human bronchial epithelial cells induce dendritic cell maturation
-
Bleck, B., Tse, D. B., Jaspers, I., Curotto de Lafaille, M. A. and Reibman, J., Diesel exhaust particle-exposed human bronchial epithelial cells induce dendritic cell maturation. J. Immunol. 2006. 176: 7431-7437.
-
(2006)
J. Immunol.
, vol.176
, pp. 7431-7437
-
-
Bleck, B.1
Tse, D.B.2
Jaspers, I.3
Curotto de Lafaille, M.A.4
Reibman, J.5
-
80
-
-
25844515028
-
Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice
-
Zhou, B., Comeau, M. R., De Smedt, T., Liggitt, H. D., Dahl, M. E., Lewis, D. B., Gyarmati, D. et al., Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice. Nat. Immunol. 2005. 6: 1047-1053.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1047-1053
-
-
Zhou, B.1
Comeau, M.R.2
De Smedt, T.3
Liggitt, H.D.4
Dahl, M.E.5
Lewis, D.B.6
Gyarmati, D.7
-
81
-
-
20444365526
-
Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity
-
Ying, S., O'Connor, B., Ratoff, J., Meng, Q., Mallett, K., Cousins, D., Robinson, D. et al., Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity. J. Immunol. 2005. 174: 8183-8190.
-
(2005)
J. Immunol.
, vol.174
, pp. 8183-8190
-
-
Ying, S.1
O'Connor, B.2
Ratoff, J.3
Meng, Q.4
Mallett, K.5
Cousins, D.6
Robinson, D.7
-
82
-
-
77950296865
-
Thymic stromal lymphopoietin-induced human asthmatic airway epithelial cell proliferation through an IL-13-dependent pathway
-
Semlali, A., Jacques, E., Koussih, L., Gounni, A. S. and Chakir, J., Thymic stromal lymphopoietin-induced human asthmatic airway epithelial cell proliferation through an IL-13-dependent pathway. J. Allergy Clin. Immunol. 2010. 125: 844-850.
-
(2010)
J. Allergy Clin. Immunol.
, vol.125
, pp. 844-850
-
-
Semlali, A.1
Jacques, E.2
Koussih, L.3
Gounni, A.S.4
Chakir, J.5
-
83
-
-
80051570509
-
Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma
-
Harada, M., Hirota, T., Jodo, A. I., Hitomi, Y., Sakashita, M., Tsunoda, T., Miyagawa, T. et al., Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma. Am. J. Respir. Cell Mol. Biol. 2011. 44: 787-793.
-
(2011)
Am. J. Respir. Cell Mol. Biol.
, vol.44
, pp. 787-793
-
-
Harada, M.1
Hirota, T.2
Jodo, A.I.3
Hitomi, Y.4
Sakashita, M.5
Tsunoda, T.6
Miyagawa, T.7
-
84
-
-
70249093313
-
Proteases induce production of thymic stromal lymphopoietin by airway epithelial cells through protease-activated receptor-2
-
Kouzaki, H., O'Grady, S. M., Lawrence, C. B. and Kita, H., Proteases induce production of thymic stromal lymphopoietin by airway epithelial cells through protease-activated receptor-2. J. Immunol. 2009. 183: 1427-1434.
-
(2009)
J. Immunol.
, vol.183
, pp. 1427-1434
-
-
Kouzaki, H.1
O'Grady, S.M.2
Lawrence, C.B.3
Kita, H.4
-
85
-
-
78650634881
-
Diesel exhaust particle-treated human bronchial epithelial cells upregulate Jagged-1 and OX40 ligand in myeloid dendritic cells via thymic stromal lymphopoietin
-
Bleck, B., Tse, D. B., Gordon, T., Ahsan, M. R. and Reibman, J., Diesel exhaust particle-treated human bronchial epithelial cells upregulate Jagged-1 and OX40 ligand in myeloid dendritic cells via thymic stromal lymphopoietin. J. Immunol. 2010. 185: 6636-6645.
-
(2010)
J. Immunol.
, vol.185
, pp. 6636-6645
-
-
Bleck, B.1
Tse, D.B.2
Gordon, T.3
Ahsan, M.R.4
Reibman, J.5
-
86
-
-
84864001201
-
DC-derived TSLP promotes Th2 polarization in LPS-primed allergic airway inflammation
-
Zhang, Y., Zhou, X. and Zhou, B., DC-derived TSLP promotes Th2 polarization in LPS-primed allergic airway inflammation. Eur. J. Immunol. 2012. 42: 1735-1743.
-
(2012)
Eur. J. Immunol.
, vol.42
, pp. 1735-1743
-
-
Zhang, Y.1
Zhou, X.2
Zhou, B.3
-
87
-
-
80052582016
-
TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation
-
Siracusa, M. C., Saenz, S. A., Hill, D. A., Kim, B. S., Headley, M. B., Doering, T. A., Wherry, E. J. et al., TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation. Nature 2011. 477: 229-233.
-
(2011)
Nature
, vol.477
, pp. 229-233
-
-
Siracusa, M.C.1
Saenz, S.A.2
Hill, D.A.3
Kim, B.S.4
Headley, M.B.5
Doering, T.A.6
Wherry, E.J.7
-
88
-
-
57349084248
-
IL-23 and Th17 cells enhance Th2-cell-mediated eosinophilic airway inflammation in mice
-
Wakashin, H., Hirose, K., Maezawa, Y., Kagami, S., Suto, A., Watanabe, N., Saito, Y. et al., IL-23 and Th17 cells enhance Th2-cell-mediated eosinophilic airway inflammation in mice. Am. J. Respir. Crit. Care Med. 2008. 178: 1023-1032.
-
(2008)
Am. J. Respir. Crit. Care Med.
, vol.178
, pp. 1023-1032
-
-
Wakashin, H.1
Hirose, K.2
Maezawa, Y.3
Kagami, S.4
Suto, A.5
Watanabe, N.6
Saito, Y.7
-
89
-
-
70349871248
-
Allergic sensitization through the airway primes Th17-dependent neutrophilia and airway hyperresponsiveness
-
Wilson, R. H., Whitehead, G. S., Nakano, H., Free, M. E., Kolls, J. K. and Cook, D. N., Allergic sensitization through the airway primes Th17-dependent neutrophilia and airway hyperresponsiveness. Am. J. Respir. Crit. Care Med. 2009. 180: 720-730.
-
(2009)
Am. J. Respir. Crit. Care Med.
, vol.180
, pp. 720-730
-
-
Wilson, R.H.1
Whitehead, G.S.2
Nakano, H.3
Free, M.E.4
Kolls, J.K.5
Cook, D.N.6
-
90
-
-
77956955243
-
Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma
-
Lajoie, S., Lewkowich, I. P., Suzuki, Y., Clark, J. R., Sproles, A. A., Dienger, K., Budelsky, A. L. et al., Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma. Nat. Immunol. 2010. 11: 928-935.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 928-935
-
-
Lajoie, S.1
Lewkowich, I.P.2
Suzuki, Y.3
Clark, J.R.4
Sproles, A.A.5
Dienger, K.6
Budelsky, A.L.7
-
91
-
-
84862776751
-
IL-17A produced by alphabeta T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction
-
Kudo, M., Melton, A. C., Chen, C., Engler, M. B., Huang, K. E., Ren, X., Wang, Y. et al., IL-17A produced by alphabeta T cells drives airway hyper-responsiveness in mice and enhances mouse and human airway smooth muscle contraction. Nat. Med. 2012. 18: 547-554.
-
(2012)
Nat. Med.
, vol.18
, pp. 547-554
-
-
Kudo, M.1
Melton, A.C.2
Chen, C.3
Engler, M.B.4
Huang, K.E.5
Ren, X.6
Wang, Y.7
-
92
-
-
77955498051
-
The overexpression of heparin-binding epidermal growth factor is responsible for Th17-induced airway remodeling in an experimental asthma model
-
Wang, Q., Li, H., Yao, Y., Xia, D. and Zhou, J., The overexpression of heparin-binding epidermal growth factor is responsible for Th17-induced airway remodeling in an experimental asthma model. J. Immunol. 2010. 185: 834-841.
-
(2010)
J. Immunol.
, vol.185
, pp. 834-841
-
-
Wang, Q.1
Li, H.2
Yao, Y.3
Xia, D.4
Zhou, J.5
-
93
-
-
39549106479
-
Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17
-
Pichavant, M., Goya, S., Meyer, E. H., Johnston, R. A., Kim, H. Y., Matangkasombut, P., Zhu, M. et al., Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17. J. Exp. Med. 2008. 205: 385-393.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 385-393
-
-
Pichavant, M.1
Goya, S.2
Meyer, E.H.3
Johnston, R.A.4
Kim, H.Y.5
Matangkasombut, P.6
Zhu, M.7
-
94
-
-
84857215266
-
Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients
-
Bellini, A., Marini, M. A., Bianchetti, L., Barczyk, M., Schmidt, M. and Mattoli, S., Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients. Mucosal Immunol. 2012. 5: 140-149.
-
(2012)
Mucosal Immunol.
, vol.5
, pp. 140-149
-
-
Bellini, A.1
Marini, M.A.2
Bianchetti, L.3
Barczyk, M.4
Schmidt, M.5
Mattoli, S.6
-
95
-
-
84874088635
-
Th17 responses in chronic allergic airway inflammation abrogate regulatory T-cell-mediated tolerance and contribute to airway remodeling
-
Zhao, J., Lloyd, C. M. and Noble, A., Th17 responses in chronic allergic airway inflammation abrogate regulatory T-cell-mediated tolerance and contribute to airway remodeling. Mucosal Immunol. 2012. 6: 335-346.
-
(2012)
Mucosal Immunol.
, vol.6
, pp. 335-346
-
-
Zhao, J.1
Lloyd, C.M.2
Noble, A.3
-
96
-
-
84856760174
-
Interleukin-17A induces glucocorticoid insensitivity in human bronchial epithelial cells
-
Zijlstra, G. J., Ten Hacken, N. H., Hoffmann, R. F., van Oosterhout, A. J. and Heijink, I. H., Interleukin-17A induces glucocorticoid insensitivity in human bronchial epithelial cells. Eur. Respir. J. 2012. 39: 439-445.
-
(2012)
Eur. Respir. J.
, vol.39
, pp. 439-445
-
-
Zijlstra, G.J.1
Ten Hacken, N.H.2
Hoffmann, R.F.3
van Oosterhout, A.J.4
Heijink, I.H.5
-
97
-
-
80555134794
-
The protective role of TLR6 in a mouse model of asthma is mediated by IL-23 and IL-17A
-
Moreira, A. P., Cavassani, K. A., Ismailoglu, U. B., Hullinger, R., Dunleavy, M. P., Knight, D. A., Kunkel, S. L. et al., The protective role of TLR6 in a mouse model of asthma is mediated by IL-23 and IL-17A. J. Clin. Invest. 2011. 121: 4420-4432.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 4420-4432
-
-
Moreira, A.P.1
Cavassani, K.A.2
Ismailoglu, U.B.3
Hullinger, R.4
Dunleavy, M.P.5
Knight, D.A.6
Kunkel, S.L.7
-
98
-
-
33751506710
-
Interleukin-17 is a negative regulator of established allergic asthma
-
Schnyder-Candrian, S., Togbe, D., Couillin, I., Mercier, I., Brombacher, F., Quesniaux, V. F., Fossiez, F. et al., Interleukin-17 is a negative regulator of established allergic asthma. J. Exp. Med. 2006. 203: 2715-2725.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2715-2725
-
-
Schnyder-Candrian, S.1
Togbe, D.2
Couillin, I.3
Mercier, I.4
Brombacher, F.5
Quesniaux, V.F.6
Fossiez, F.7
-
99
-
-
26444608592
-
Evaluation of the toll-like receptor 6 Ser249Pro polymorphism in patients with asthma, atopic dermatitis and chronic obstructive pulmonary disease
-
Hoffjan, S., Stemmler, S., Parwez, Q., Petrasch-Parwez, E., Arinir, U., Rohde, G., Reinitz-Rademacher, K. et al., Evaluation of the toll-like receptor 6 Ser249Pro polymorphism in patients with asthma, atopic dermatitis and chronic obstructive pulmonary disease. BMC Med. Genet. 2005. 6: 34.
-
(2005)
BMC Med. Genet.
, vol.6
, pp. 34
-
-
Hoffjan, S.1
Stemmler, S.2
Parwez, Q.3
Petrasch-Parwez, E.4
Arinir, U.5
Rohde, G.6
Reinitz-Rademacher, K.7
-
100
-
-
38849187386
-
IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation
-
Ma, H. L., Liang, S., Li, J., Napierata, L., Brown, T., Benoit, S., Senices, M. et al., IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasis-like skin inflammation. J. Clin. Invest. 2008. 118: 597-607.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 597-607
-
-
Ma, H.L.1
Liang, S.2
Li, J.3
Napierata, L.4
Brown, T.5
Benoit, S.6
Senices, M.7
-
101
-
-
33846906224
-
Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
-
Zheng, Y., Danilenko, D. M., Valdez, P., Kasman, I., Eastham-Anderson, J., Wu, J. and Ouyang, W., Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature 2007. 445: 648-651.
-
(2007)
Nature
, vol.445
, pp. 648-651
-
-
Zheng, Y.1
Danilenko, D.M.2
Valdez, P.3
Kasman, I.4
Eastham-Anderson, J.5
Wu, J.6
Ouyang, W.7
-
102
-
-
38849141814
-
IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis
-
Sugimoto, K., Ogawa, A., Mizoguchi, E., Shimomura, Y., Andoh, A., Bhan, A. K., Blumberg, R. S. et al., IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis. J. Clin. Invest. 2008. 118: 534-544.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 534-544
-
-
Sugimoto, K.1
Ogawa, A.2
Mizoguchi, E.3
Shimomura, Y.4
Andoh, A.5
Bhan, A.K.6
Blumberg, R.S.7
-
103
-
-
80053016614
-
Increased expression of aryl hydrocarbon receptor and interleukin 22 in patients with allergic asthma
-
Zhu, J., Cao, Y., Li, K., Wang, Z., Zuo, P., Xiong, W., Xu, Y. et al., Increased expression of aryl hydrocarbon receptor and interleukin 22 in patients with allergic asthma. Asian Pac. J. Allergy Immunol. 2011. 29: 266-272.
-
(2011)
Asian Pac. J. Allergy Immunol.
, vol.29
, pp. 266-272
-
-
Zhu, J.1
Cao, Y.2
Li, K.3
Wang, Z.4
Zuo, P.5
Xiong, W.6
Xu, Y.7
-
104
-
-
79960581219
-
IL-22 is produced by innate lymphoid cells and limits inflammation in allergic airway disease
-
Taube, C., Tertilt, C., Gyulveszi, G., Dehzad, N., Kreymborg, K., Schneeweiss, K., Michel, E. et al., IL-22 is produced by innate lymphoid cells and limits inflammation in allergic airway disease. PLoS One 2011. 6: e21799.
-
(2011)
PLoS One
, vol.6
-
-
Taube, C.1
Tertilt, C.2
Gyulveszi, G.3
Dehzad, N.4
Kreymborg, K.5
Schneeweiss, K.6
Michel, E.7
-
105
-
-
80055073732
-
IL-22 attenuates IL-25 production by lung epithelial cells and inhibits antigen-induced eosinophilic airway inflammation
-
e1061-1066.
-
Takahashi, K., Hirose, K., Kawashima, S., Niwa, Y., Wakashin, H., Iwata, A., Tokoyoda, K. et al., IL-22 attenuates IL-25 production by lung epithelial cells and inhibits antigen-induced eosinophilic airway inflammation. J. Allergy Clin. Immunol. 2011. 128: 1067-1076 e1061-1066.
-
(2011)
J. Allergy Clin. Immunol.
, vol.128
, pp. 1067-1076
-
-
Takahashi, K.1
Hirose, K.2
Kawashima, S.3
Niwa, Y.4
Wakashin, H.5
Iwata, A.6
Tokoyoda, K.7
-
106
-
-
79955499768
-
Dual Role of IL-22 in allergic airway inflammation and its cross-talk with IL-17A
-
Besnard, A. G., Sabat, R., Dumoutier, L., Renauld, J. C., Willart, M., Lambrecht, B., Teixeira, M. M. et al., Dual Role of IL-22 in allergic airway inflammation and its cross-talk with IL-17A. Am. J. Respir. Crit. Care Med. 2011. 183: 1153-1163.
-
(2011)
Am. J. Respir. Crit. Care Med.
, vol.183
, pp. 1153-1163
-
-
Besnard, A.G.1
Sabat, R.2
Dumoutier, L.3
Renauld, J.C.4
Willart, M.5
Lambrecht, B.6
Teixeira, M.M.7
-
107
-
-
84873412150
-
IL-22 suppresses IFN-gamma-mediated lung inflammation in asthmatic patients
-
Pennino, D., Bhavsar, P. K., Effner, R., Avitabile, S., Venn, P., Quaranta, M., Marzaioli, V. et al., IL-22 suppresses IFN-gamma-mediated lung inflammation in asthmatic patients. J. Allergy Clin. Immunol. 2013. 131: 562-570.
-
(2013)
J. Allergy Clin. Immunol.
, vol.131
, pp. 562-570
-
-
Pennino, D.1
Bhavsar, P.K.2
Effner, R.3
Avitabile, S.4
Venn, P.5
Quaranta, M.6
Marzaioli, V.7
-
108
-
-
81455131846
-
High expression of IL-22 suppresses antigen-induced immune responses and eosinophilic airway inflammation via an IL-10-associated mechanism
-
Nakagome, K., Imamura, M., Kawahata, K., Harada, H., Okunishi, K., Matsumoto, T., Sasaki, O. et al., High expression of IL-22 suppresses antigen-induced immune responses and eosinophilic airway inflammation via an IL-10-associated mechanism. J. Immunol. 2011. 187: 5077-5089.
-
(2011)
J. Immunol.
, vol.187
, pp. 5077-5089
-
-
Nakagome, K.1
Imamura, M.2
Kawahata, K.3
Harada, H.4
Okunishi, K.5
Matsumoto, T.6
Sasaki, O.7
-
109
-
-
84868615556
-
IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine
-
Huber, S., Gagliani, N., Zenewicz, L. A., Huber, F. J., Bosurgi, L., Hu, B., Hedl, M. et al., IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine. Nature 2012. 491: 259-263.
-
(2012)
Nature
, vol.491
, pp. 259-263
-
-
Huber, S.1
Gagliani, N.2
Zenewicz, L.A.3
Huber, F.J.4
Bosurgi, L.5
Hu, B.6
Hedl, M.7
-
110
-
-
84866542660
-
The beta-glucan receptor dectin-1 promotes lung immunopathology during fungal allergy via IL-22
-
Lilly, L. M., Gessner, M. A., Dunaway, C. W., Metz, A. E., Schwiebert, L., Weaver, C. T., Brown, G. D. et al., The beta-glucan receptor dectin-1 promotes lung immunopathology during fungal allergy via IL-22. J. Immunol. 2012. 189: 3653-3660.
-
(2012)
J. Immunol.
, vol.189
, pp. 3653-3660
-
-
Lilly, L.M.1
Gessner, M.A.2
Dunaway, C.W.3
Metz, A.E.4
Schwiebert, L.5
Weaver, C.T.6
Brown, G.D.7
-
111
-
-
56349154943
-
Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
-
Veldhoen, M., Uyttenhove, C., van Snick, J., Helmby, H., Westendorf, A., Buer, J., Martin, B. et al., Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat. Immunol. 2008. 9: 1341-1346.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 1341-1346
-
-
Veldhoen, M.1
Uyttenhove, C.2
van Snick, J.3
Helmby, H.4
Westendorf, A.5
Buer, J.6
Martin, B.7
-
112
-
-
77955902281
-
Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells
-
Staudt, V., Bothur, E., Klein, M., Lingnau, K., Reuter, S., Grebe, N., Gerlitzki, B. et al., Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells. Immunity 2010. 33: 192-202.
-
(2010)
Immunity
, vol.33
, pp. 192-202
-
-
Staudt, V.1
Bothur, E.2
Klein, M.3
Lingnau, K.4
Reuter, S.5
Grebe, N.6
Gerlitzki, B.7
-
113
-
-
84863010992
-
STAT6-dependent regulation of Th9 development
-
Goswami, R., Jabeen, R., Yagi, R., Pham, D., Zhu, J., Goenka, S. and Kaplan, M. H., STAT6-dependent regulation of Th9 development. J. Immunol. 2012. 188: 968-975.
-
(2012)
J. Immunol.
, vol.188
, pp. 968-975
-
-
Goswami, R.1
Jabeen, R.2
Yagi, R.3
Pham, D.4
Zhu, J.5
Goenka, S.6
Kaplan, M.H.7
-
114
-
-
84859997488
-
Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells
-
Elyaman, W., Bassil, R., Bradshaw, E. M., Orent, W., Lahoud, Y., Zhu, B., Radtke, F. et al., Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells. Immunity 2012. 36: 623-634.
-
(2012)
Immunity
, vol.36
, pp. 623-634
-
-
Elyaman, W.1
Bassil, R.2
Bradshaw, E.M.3
Orent, W.4
Lahoud, Y.5
Zhu, B.6
Radtke, F.7
-
115
-
-
79953327120
-
IL-9 governs allergen-induced mast cell numbers in the lung and chronic remodeling of the airways
-
Kearley, J., Erjefalt, J. S., Andersson, C., Benjamin, E., Jones, C. P., Robichaud, A., Pegorier, S. et al., IL-9 governs allergen-induced mast cell numbers in the lung and chronic remodeling of the airways. Am. J. Respir. Crit. Care Med. 2011. 183: 865-875.
-
(2011)
Am. J. Respir. Crit. Care Med.
, vol.183
, pp. 865-875
-
-
Kearley, J.1
Erjefalt, J.S.2
Andersson, C.3
Benjamin, E.4
Jones, C.P.5
Robichaud, A.6
Pegorier, S.7
-
116
-
-
0038518063
-
Segmental allergen challenge in patients with atopic asthma leads to increased IL-9 expression in bronchoalveolar lavage fluid lymphocytes
-
Erpenbeck, V. J., Hohlfeld, J. M., Volkmann, B., Hagenberg, A., Geldmacher, H., Braun, A. and Krug, N., Segmental allergen challenge in patients with atopic asthma leads to increased IL-9 expression in bronchoalveolar lavage fluid lymphocytes. J. Allergy Clin. Immunol. 2003. 111: 1319-1327.
-
(2003)
J. Allergy Clin. Immunol.
, vol.111
, pp. 1319-1327
-
-
Erpenbeck, V.J.1
Hohlfeld, J.M.2
Volkmann, B.3
Hagenberg, A.4
Geldmacher, H.5
Braun, A.6
Krug, N.7
-
117
-
-
0036141448
-
Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology
-
Temann, U. A., Ray, P. and Flavell, R. A., Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology. J. Clin. Invest. 2002. 109: 29-39.
-
(2002)
J. Clin. Invest.
, vol.109
, pp. 29-39
-
-
Temann, U.A.1
Ray, P.2
Flavell, R.A.3
-
118
-
-
0032487434
-
Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness
-
Temann, U. A., Geba, G. P., Rankin, J. A. and Flavell, R. A., Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness. J. Exp. Med. 1998. 188: 1307-1320.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 1307-1320
-
-
Temann, U.A.1
Geba, G.P.2
Rankin, J.A.3
Flavell, R.A.4
-
119
-
-
84875733865
-
Programmed cell death ligand 2 regulates T(H)9 differentiation and induction of chronic airway hyperreactivity
-
Kerzerho, J., Maazi, H., Speak, A. O., Szely, N., Lombardi, V., Khoo, B., Geryak, S. et al., Programmed cell death ligand 2 regulates T(H)9 differentiation and induction of chronic airway hyperreactivity. J. Allergy Clin. Immunol. 2012. 131: 1048-1057.
-
(2012)
J. Allergy Clin. Immunol.
, vol.131
, pp. 1048-1057
-
-
Kerzerho, J.1
Maazi, H.2
Speak, A.O.3
Szely, N.4
Lombardi, V.5
Khoo, B.6
Geryak, S.7
-
120
-
-
46749126890
-
Adaptive Foxp3+ regulatory T cell-dependent and -independent control of allergic inflammation
-
Curotto de Lafaille, M. A., Kutchukhidze, N., Shen, S., Ding, Y., Yee, H. and Lafaille, J. J., Adaptive Foxp3+ regulatory T cell-dependent and -independent control of allergic inflammation. Immunity 2008. 29: 114-126.
-
(2008)
Immunity
, vol.29
, pp. 114-126
-
-
Curotto de Lafaille, M.A.1
Kutchukhidze, N.2
Shen, S.3
Ding, Y.4
Yee, H.5
Lafaille, J.J.6
-
121
-
-
84862777225
-
Extrathymically generated regulatory T cells control mucosal TH2 inflammation
-
Josefowicz, S. Z., Niec, R. E., Kim, H. Y., Treuting, P., Chinen, T., Zheng, Y., Umetsu, D. T. et al., Extrathymically generated regulatory T cells control mucosal TH2 inflammation. Nature 2012. 482: 395-399.
-
(2012)
Nature
, vol.482
, pp. 395-399
-
-
Josefowicz, S.Z.1
Niec, R.E.2
Kim, H.Y.3
Treuting, P.4
Chinen, T.5
Zheng, Y.6
Umetsu, D.T.7
-
122
-
-
3242754344
-
Tolerance induced by inhaled antigen involves CD4(+) T cells expressing membrane-bound TGF-beta and FOXP3
-
Ostroukhova, M., Seguin-Devaux, C., Oriss, T. B., Dixon-McCarthy, B., Yang, L., Ameredes, B. T., Corcoran, T. E. et al., Tolerance induced by inhaled antigen involves CD4(+) T cells expressing membrane-bound TGF-beta and FOXP3. J. Clin. Invest. 2004. 114: 28-38.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 28-38
-
-
Ostroukhova, M.1
Seguin-Devaux, C.2
Oriss, T.B.3
Dixon-McCarthy, B.4
Yang, L.5
Ameredes, B.T.6
Corcoran, T.E.7
-
123
-
-
77956125994
-
Selective depletion of Foxp3+ Treg during sensitization phase aggravates experimental allergic airway inflammation
-
Baru, A. M., Hartl, A., Lahl, K., Krishnaswamy, J. K., Fehrenbach, H., Yildirim, A. O., Garn, H. et al., Selective depletion of Foxp3+ Treg during sensitization phase aggravates experimental allergic airway inflammation. Eur. J. Immunol. 2010. 40: 2259-2266.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 2259-2266
-
-
Baru, A.M.1
Hartl, A.2
Lahl, K.3
Krishnaswamy, J.K.4
Fehrenbach, H.5
Yildirim, A.O.6
Garn, H.7
-
124
-
-
84867899425
-
Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells
-
S1721.
-
Weiss, J. M., Bilate, A. M., Gobert, M., Ding, Y., Curotto de Lafaille, M. A., Parkhurst, C. N., Xiong, H. et al., Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells. J. Exp. Med. 2012. 209: 1723-1742, S1721.
-
(2012)
J. Exp. Med.
, vol.209
, pp. 1723-1742
-
-
Weiss, J.M.1
Bilate, A.M.2
Gobert, M.3
Ding, Y.4
Curotto de Lafaille, M.A.5
Parkhurst, C.N.6
Xiong, H.7
-
125
-
-
50649121609
-
CD4+CD25+ regulatory T cells reverse established allergic airway inflammation and prevent airway remodeling
-
e616.
-
Kearley, J., Robinson, D. S. and Lloyd, C. M., CD4+CD25+ regulatory T cells reverse established allergic airway inflammation and prevent airway remodeling. J. Allergy Clin. Immunol. 2008. 122: 617-624 e616.
-
(2008)
J. Allergy Clin. Immunol.
, vol.122
, pp. 617-624
-
-
Kearley, J.1
Robinson, D.S.2
Lloyd, C.M.3
-
126
-
-
28544444024
-
Resolution of airway inflammation and hyperreactivity after in vivo transfer of CD4+CD25+ regulatory T cells is interleukin 10 dependent
-
Kearley, J., Barker, J. E., Robinson, D. S. and Lloyd, C. M., Resolution of airway inflammation and hyperreactivity after in vivo transfer of CD4+CD25+ regulatory T cells is interleukin 10 dependent. J. Exp. Med. 2005. 202: 1539-1547.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 1539-1547
-
-
Kearley, J.1
Barker, J.E.2
Robinson, D.S.3
Lloyd, C.M.4
-
127
-
-
28544432829
-
CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function
-
Lewkowich, I. P., Herman, N. S., Schleifer, K. W., Dance, M. P., Chen, B. L., Dienger, K. M., Sproles, A. A. et al., CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function. J. Exp. Med. 2005. 202: 1549-1561.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 1549-1561
-
-
Lewkowich, I.P.1
Herman, N.S.2
Schleifer, K.W.3
Dance, M.P.4
Chen, B.L.5
Dienger, K.M.6
Sproles, A.A.7
-
128
-
-
70449729967
-
Regulatory T cells negatively regulate neovasculature of airway remodeling via DLL4-Notch signaling
-
Huang, M. T., Dai, Y. S., Chou, Y. B., Juan, Y. H., Wang, C. C. and Chiang, B. L., Regulatory T cells negatively regulate neovasculature of airway remodeling via DLL4-Notch signaling. J. Immunol. 2009. 183: 4745-4754.
-
(2009)
J. Immunol.
, vol.183
, pp. 4745-4754
-
-
Huang, M.T.1
Dai, Y.S.2
Chou, Y.B.3
Juan, Y.H.4
Wang, C.C.5
Chiang, B.L.6
-
129
-
-
84455199735
-
IL-35 production by inducible costimulator (ICOS)-positive regulatory T cells reverses established IL-17-dependent allergic airways disease
-
and, e201-205.
-
Whitehead, G. S., Wilson, R. H., Nakano, K., Burch, L. H., Nakano, H. and Cook, D. N., IL-35 production by inducible costimulator (ICOS)-positive regulatory T cells reverses established IL-17-dependent allergic airways disease. J. Allergy Clin. Immunol. 2012. 129: 207-215 e201-205.
-
(2012)
J. Allergy Clin. Immunol.
, vol.129
, pp. 207-215
-
-
Whitehead, G.S.1
Wilson, R.H.2
Nakano, K.3
Burch, L.H.4
Nakano, H.5
Cook, D.N.6
-
130
-
-
34247526094
-
Quantitative and functional impairment of pulmonary CD4+CD25hi regulatory T cells in pediatric asthma
-
Hartl, D., Koller, B., Mehlhorn, A. T., Reinhardt, D., Nicolai, T., Schendel, D. J., Griese, M. et al., Quantitative and functional impairment of pulmonary CD4+CD25hi regulatory T cells in pediatric asthma. J. Allergy Clin. Immunol. 2007. 119: 1258-1266.
-
(2007)
J. Allergy Clin. Immunol.
, vol.119
, pp. 1258-1266
-
-
Hartl, D.1
Koller, B.2
Mehlhorn, A.T.3
Reinhardt, D.4
Nicolai, T.5
Schendel, D.J.6
Griese, M.7
-
131
-
-
77957843236
-
Increased airway T regulatory cells in asthmatic subjects
-
Smyth, L. J., Eustace, A., Kolsum, U., Blaikely, J. and Singh, D., Increased airway T regulatory cells in asthmatic subjects. Chest 2010. 138: 905-912.
-
(2010)
Chest
, vol.138
, pp. 905-912
-
-
Smyth, L.J.1
Eustace, A.2
Kolsum, U.3
Blaikely, J.4
Singh, D.5
-
132
-
-
78649397627
-
TSLP directly impairs pulmonary Treg function: association with aberrant tolerogenic immunity in asthmatic airway
-
Nguyen, K. D., Vanichsarn, C. and Nadeau, K. C., TSLP directly impairs pulmonary Treg function: association with aberrant tolerogenic immunity in asthmatic airway. Allergy Asthma Clin. Immunol. 2010. 6: 4.
-
(2010)
Allergy Asthma Clin. Immunol.
, vol.6
, pp. 4
-
-
Nguyen, K.D.1
Vanichsarn, C.2
Nadeau, K.C.3
-
133
-
-
0034890907
-
Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen
-
Akbari, O., DeKruyff, R. H. and Umetsu, D. T., Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen. Nat. Immunol. 2001. 2: 725-731.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 725-731
-
-
Akbari, O.1
DeKruyff, R.H.2
Umetsu, D.T.3
-
134
-
-
33847143728
-
Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells
-
Hammad, H., Kool, M., Soullie, T., Narumiya, S., Trottein, F., Hoogsteden, H. C. and Lambrecht, B. N., Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells. J. Exp. Med. 2007. 204: 357-367.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 357-367
-
-
Hammad, H.1
Kool, M.2
Soullie, T.3
Narumiya, S.4
Trottein, F.5
Hoogsteden, H.C.6
Lambrecht, B.N.7
-
135
-
-
84864857933
-
CD8alpha(+)beta(-) and CD8alpha(+)beta(+) plasmacytoid dendritic cells induce Foxp3(+) regulatory T cells and prevent the induction of airway hyper-reactivity
-
Lombardi, V., Speak, A. O., Kerzerho, J., Szely, N. and Akbari, O., CD8alpha(+)beta(-) and CD8alpha(+)beta(+) plasmacytoid dendritic cells induce Foxp3(+) regulatory T cells and prevent the induction of airway hyper-reactivity. Mucosal. Immunol. 2012. 5: 432-443.
-
(2012)
Mucosal. Immunol.
, vol.5
, pp. 432-443
-
-
Lombardi, V.1
Speak, A.O.2
Kerzerho, J.3
Szely, N.4
Akbari, O.5
-
136
-
-
84878659255
-
Lung-resident tissue macrophages generate Foxp3+ regulatory T cells and promote airway tolerance
-
Soroosh, P., Doherty, T. A., Duan, W., Mehta, A. K., Choi, H., Adams, Y. F., Mikulski, Z. et al., Lung-resident tissue macrophages generate Foxp3+ regulatory T cells and promote airway tolerance. J. Exp. Med. 2013. 210: 775-788.
-
(2013)
J. Exp. Med.
, vol.210
, pp. 775-788
-
-
Soroosh, P.1
Doherty, T.A.2
Duan, W.3
Mehta, A.K.4
Choi, H.5
Adams, Y.F.6
Mikulski, Z.7
-
137
-
-
84878551912
-
Compartmentalized chemokine-dependent regulatory T-cell inhibition of allergic pulmonary inflammation
-
Afshar, R., Strassner, J. P., Seung, E., Causton, B., Cho, J. L., Harris, R. S., Hamilos, D. L. et al., Compartmentalized chemokine-dependent regulatory T-cell inhibition of allergic pulmonary inflammation. J. Allergy Clin. Immunol. 2013. 131: 1644-1652.
-
(2013)
J. Allergy Clin. Immunol.
, vol.131
, pp. 1644-1652
-
-
Afshar, R.1
Strassner, J.P.2
Seung, E.3
Causton, B.4
Cho, J.L.5
Harris, R.S.6
Hamilos, D.L.7
-
138
-
-
84857220793
-
Directed antigen targeting in vivo identifies a role for CD103+ dendritic cells in both tolerogenic and immunogenic T-cell responses
-
Semmrich, M., Plantinga, M., Svensson-Frej, M., Uronen-Hansson, H., Gustafsson, T., Mowat, A. M., Yrlid, U. et al., Directed antigen targeting in vivo identifies a role for CD103+ dendritic cells in both tolerogenic and immunogenic T-cell responses. Mucosal Immunol. 2012. 5: 150-160.
-
(2012)
Mucosal Immunol.
, vol.5
, pp. 150-160
-
-
Semmrich, M.1
Plantinga, M.2
Svensson-Frej, M.3
Uronen-Hansson, H.4
Gustafsson, T.5
Mowat, A.M.6
Yrlid, U.7
-
139
-
-
84862777474
-
Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation
-
Hill, D. A., Siracusa, M. C., Abt, M. C., Kim, B. S., Kobuley, D., Kubo, M., Kambayashi, T. et al., Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation. Nat. Med. 2012. 18: 538-546.
-
(2012)
Nat. Med.
, vol.18
, pp. 538-546
-
-
Hill, D.A.1
Siracusa, M.C.2
Abt, M.C.3
Kim, B.S.4
Kobuley, D.5
Kubo, M.6
Kambayashi, T.7
-
140
-
-
84860216630
-
Microbial exposure during early life has persistent effects on natural killer T cell function
-
Olszak, T., An, D., Zeissig, S., Vera, M. P., Richter, J., Franke, A., Glickman, J. N. et al., Microbial exposure during early life has persistent effects on natural killer T cell function. Science 2012. 336: 489-493.
-
(2012)
Science
, vol.336
, pp. 489-493
-
-
Olszak, T.1
An, D.2
Zeissig, S.3
Vera, M.P.4
Richter, J.5
Franke, A.6
Glickman, J.N.7
-
141
-
-
80051570891
-
Dysregulation of allergic airway inflammation in the absence of microbial colonization
-
Herbst, T., Sichelstiel, A., Schar, C., Yadava, K., Burki, K., Cahenzli, J., McCoy, K. et al., Dysregulation of allergic airway inflammation in the absence of microbial colonization. Am. J. Respir. Crit. Care Med. 2011. 184: 198-205.
-
(2011)
Am. J. Respir. Crit. Care Med.
, vol.184
, pp. 198-205
-
-
Herbst, T.1
Sichelstiel, A.2
Schar, C.3
Yadava, K.4
Burki, K.5
Cahenzli, J.6
McCoy, K.7
-
142
-
-
70350666634
-
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
-
Maslowski, K. M., Vieira, A. T., Ng, A., Kranich, J., Sierro, F., Yu, D., Schilter, H. C. et al., Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43. Nature 2009. 461: 1282-1286.
-
(2009)
Nature
, vol.461
, pp. 1282-1286
-
-
Maslowski, K.M.1
Vieira, A.T.2
Ng, A.3
Kranich, J.4
Sierro, F.5
Yu, D.6
Schilter, H.C.7
-
143
-
-
84860436361
-
Early life antibiotic-driven changes in microbiota enhance susceptibility to allergic asthma
-
Russell, S. L., Gold, M. J., Hartmann, M., Willing, B. P., Thorson, L., Wlodarska, M., Gill, N. et al., Early life antibiotic-driven changes in microbiota enhance susceptibility to allergic asthma. EMBO Rep. 2012. 13: 440-447.
-
(2012)
EMBO Rep.
, vol.13
, pp. 440-447
-
-
Russell, S.L.1
Gold, M.J.2
Hartmann, M.3
Willing, B.P.4
Thorson, L.5
Wlodarska, M.6
Gill, N.7
-
144
-
-
79551495183
-
Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma
-
e371-373.
-
Huang, Y. J., Nelson, C. E., Brodie, E. L., Desantis, T. Z., Baek, M. S., Liu, J., Woyke, T. et al., Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma. J. Allergy Clin. Immunol. 2011. 127: 372-381 e371-373.
-
(2011)
J. Allergy Clin. Immunol.
, vol.127
, pp. 372-381
-
-
Huang, Y.J.1
Nelson, C.E.2
Brodie, E.L.3
Desantis, T.Z.4
Baek, M.S.5
Liu, J.6
Woyke, T.7
-
145
-
-
0036379740
-
Preclinical efficacy and safety of pascolizumab (SB 240683): a humanized anti-interleukin-4 antibody with therapeutic potential in asthma
-
Hart, T. K., Blackburn, M. N., Brigham-Burke, M., Dede, K., Al-Mahdi, N., Zia-Amirhosseini, P. and Cook, R. M., Preclinical efficacy and safety of pascolizumab (SB 240683): a humanized anti-interleukin-4 antibody with therapeutic potential in asthma. Clin. Exp. Immunol. 2002. 130: 93-100.
-
(2002)
Clin. Exp. Immunol.
, vol.130
, pp. 93-100
-
-
Hart, T.K.1
Blackburn, M.N.2
Brigham-Burke, M.3
Dede, K.4
Al-Mahdi, N.5
Zia-Amirhosseini, P.6
Cook, R.M.7
-
146
-
-
35348909044
-
Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies
-
Wenzel, S., Wilbraham, D., Fuller, R., Getz, E. B. and Longphre, M., Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies. Lancet 2007. 370: 1422-1431.
-
(2007)
Lancet
, vol.370
, pp. 1422-1431
-
-
Wenzel, S.1
Wilbraham, D.2
Fuller, R.3
Getz, E.B.4
Longphre, M.5
-
147
-
-
80053084755
-
Lebrikizumab treatment in adults with asthma
-
Corren, J., Lemanske, R. F., Hanania, N. A., Korenblat, P. E., Parsey, M. V., Arron, J. R., Harris, J. M. et al., Lebrikizumab treatment in adults with asthma. N. Engl. J. Med. 2011. 365: 1088-1098.
-
(2011)
N. Engl. J. Med.
, vol.365
, pp. 1088-1098
-
-
Corren, J.1
Lemanske, R.F.2
Hanania, N.A.3
Korenblat, P.E.4
Parsey, M.V.5
Arron, J.R.6
Harris, J.M.7
-
148
-
-
76749141384
-
A phase 1 study evaluating the pharmacokinetics, safety and tolerability of repeat dosing with a human IL-13 antibody (CAT-354) in subjects with asthma
-
Singh, D., Kane, B., Molfino, N. A., Faggioni, R., Roskos, L. and Woodcock, A., A phase 1 study evaluating the pharmacokinetics, safety and tolerability of repeat dosing with a human IL-13 antibody (CAT-354) in subjects with asthma. BMC Pulm. Med. 2010. 10: 3.
-
(2010)
BMC Pulm. Med.
, vol.10
, pp. 3
-
-
Singh, D.1
Kane, B.2
Molfino, N.A.3
Faggioni, R.4
Roskos, L.5
Woodcock, A.6
-
149
-
-
84871013520
-
Th2 cytokine antagonists: potential treatments for severe asthma
-
Hansbro, P. M., Scott, G. V., Essilfie, A. T., Kim, R. Y., Starkey, M. R., Nguyen, D. H., Allen, P. D. et al., Th2 cytokine antagonists: potential treatments for severe asthma. Exp. Opin. Investig. Drugs 2013. 22: 49-69.
-
(2013)
Exp. Opin. Investig. Drugs
, vol.22
, pp. 49-69
-
-
Hansbro, P.M.1
Scott, G.V.2
Essilfie, A.T.3
Kim, R.Y.4
Starkey, M.R.5
Nguyen, D.H.6
Allen, P.D.7
-
150
-
-
77953039047
-
A randomized, controlled, phase 2 study of AMG 317, an IL-4Ralpha antagonist, in patients with asthma
-
Corren, J., Busse, W., Meltzer, E. O., Mansfield, L., Bensch, G., Fahrenholz, J., Wenzel, S. E. et al., A randomized, controlled, phase 2 study of AMG 317, an IL-4Ralpha antagonist, in patients with asthma. Am. J. Respir. Crit. Care Med. 2010. 181: 788-796.
-
(2010)
Am. J. Respir. Crit. Care Med.
, vol.181
, pp. 788-796
-
-
Corren, J.1
Busse, W.2
Meltzer, E.O.3
Mansfield, L.4
Bensch, G.5
Fahrenholz, J.6
Wenzel, S.E.7
-
151
-
-
84879401471
-
Dupilumab in persistent asthma with elevated eosinophil levels
-
Wenzel, S., Ford, L., Pearlman, D., Spector, S., Sher, L., Skobieranda, F., Wang, L. et al., Dupilumab in persistent asthma with elevated eosinophil levels. N. Engl. J. Med. 2013. 368: 2455-2466.
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 2455-2466
-
-
Wenzel, S.1
Ford, L.2
Pearlman, D.3
Spector, S.4
Sher, L.5
Skobieranda, F.6
Wang, L.7
-
152
-
-
6644229440
-
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response
-
Leckie, M. J., ten Brinke, A., Khan, J., Diamant, Z., O'Connor, B. J., Walls, C. M., Mathur, A. K. et al., Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response. Lancet 2000. 356: 2144-2148.
-
(2000)
Lancet
, vol.356
, pp. 2144-2148
-
-
Leckie, M.J.1
ten Brinke, A.2
Khan, J.3
Diamant, Z.4
O'Connor, B.J.5
Walls, C.M.6
Mathur, A.K.7
-
153
-
-
0038643527
-
Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: a pilot study
-
Kips, J. C., O'Connor, B. J., Langley, S. J., Woodcock, A., Kerstjens, H. A., Postma, D. S., Danzig, M. et al., Effect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: a pilot study. Am. J. Respir. Crit. Care Med. 2003. 167: 1655-1659.
-
(2003)
Am. J. Respir. Crit. Care Med.
, vol.167
, pp. 1655-1659
-
-
Kips, J.C.1
O'Connor, B.J.2
Langley, S.J.3
Woodcock, A.4
Kerstjens, H.A.5
Postma, D.S.6
Danzig, M.7
-
154
-
-
77952733788
-
MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function
-
e1342.
-
Kolbeck, R., Kozhich, A., Koike, M., Peng, L., Andersson, C. K., Damschroder, M. M., Reed, J. L. et al., MEDI-563, a humanized anti-IL-5 receptor alpha mAb with enhanced antibody-dependent cell-mediated cytotoxicity function. J. Allergy Clin. Immunol. 2010. 125: 1344-1353 e1342.
-
(2010)
J. Allergy Clin. Immunol.
, vol.125
, pp. 1344-1353
-
-
Kolbeck, R.1
Kozhich, A.2
Koike, M.3
Peng, L.4
Andersson, C.K.5
Damschroder, M.M.6
Reed, J.L.7
-
155
-
-
79952049626
-
Safety profile and clinical activity of multiple subcutaneous doses of MEDI-528, a humanized anti-interleukin-9 monoclonal antibody, in two randomized phase 2a studies in subjects with asthma
-
Parker, J. M., Oh, C. K., LaForce, C., Miller, S. D., Pearlman, D. S., Le, C., Robbie, G. J. et al., Safety profile and clinical activity of multiple subcutaneous doses of MEDI-528, a humanized anti-interleukin-9 monoclonal antibody, in two randomized phase 2a studies in subjects with asthma. BMC Pulm. Med. 2011. 11: 14.
-
(2011)
BMC Pulm. Med.
, vol.11
, pp. 14
-
-
Parker, J.M.1
Oh, C.K.2
LaForce, C.3
Miller, S.D.4
Pearlman, D.S.5
Le, C.6
Robbie, G.J.7
-
156
-
-
70049094943
-
Regulatory T cells in asthma
-
Lloyd, C. M. and Hawrylowicz, C. M., Regulatory T cells in asthma. Immunity 2009. 31: 438-449.
-
(2009)
Immunity
, vol.31
, pp. 438-449
-
-
Lloyd, C.M.1
Hawrylowicz, C.M.2
-
157
-
-
79960843789
-
Helicobacter pylori infection prevents allergic asthma in mouse models through the induction of regulatory T cells
-
Arnold, I. C., Dehzad, N., Reuter, S., Martin, H., Becher, B., Taube, C. and Muller, A., Helicobacter pylori infection prevents allergic asthma in mouse models through the induction of regulatory T cells. J. Clin. Invest. 2011. 121: 3088-3093.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 3088-3093
-
-
Arnold, I.C.1
Dehzad, N.2
Reuter, S.3
Martin, H.4
Becher, B.5
Taube, C.6
Muller, A.7
-
158
-
-
76249119555
-
Mycobacterium bovis bacillus Calmette-Guerin killed by extended freeze-drying targets plasmacytoid dendritic cells to regulate lung inflammation
-
Lagranderie, M., Abolhassani, M., Vanoirbeek, J. A., Lima, C., Balazuc, A. M., Vargaftig, B. B. and yMarchal, G., Mycobacterium bovis bacillus Calmette-Guerin killed by extended freeze-drying targets plasmacytoid dendritic cells to regulate lung inflammation. J. Immunol. 2010. 184: 1062-1070.
-
(2010)
J. Immunol.
, vol.184
, pp. 1062-1070
-
-
Lagranderie, M.1
Abolhassani, M.2
Vanoirbeek, J.A.3
Lima, C.4
Balazuc, A.M.5
Vargaftig, B.B.6
yMarchal, G.7
-
159
-
-
78149261083
-
Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-beta pathway
-
Grainger, J. R., Smith, K. A., Hewitson, J. P., McSorley, H. J., Harcus, Y., Filbey, K. J., Finney, C. A. et al., Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-beta pathway. J. Exp. Med. 2010. 207: 2331-2341.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 2331-2341
-
-
Grainger, J.R.1
Smith, K.A.2
Hewitson, J.P.3
McSorley, H.J.4
Harcus, Y.5
Filbey, K.J.6
Finney, C.A.7
-
160
-
-
77957828102
-
Therapeutic Treg expansion in mice by TNFRSF25 prevents allergic lung inflammation
-
Schreiber, T. H., Wolf, D., Tsai, M. S., Chirinos, J., Deyev, V. V., Gonzalez, L., Malek, T. R. et al., Therapeutic Treg expansion in mice by TNFRSF25 prevents allergic lung inflammation. J. Clin. Invest. 2010. 120: 3629-3640.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 3629-3640
-
-
Schreiber, T.H.1
Wolf, D.2
Tsai, M.S.3
Chirinos, J.4
Deyev, V.V.5
Gonzalez, L.6
Malek, T.R.7
-
161
-
-
84874644108
-
Modified Foxp3 mRNA protects against asthma through an IL-10-dependent mechanism
-
Mays, L. E., Ammon-Treiber, S., Mothes, B., Alkhaled, M., Rottenberger, J., Muller-Hermelink, E. S., Grimm, M. et al., Modified Foxp3 mRNA protects against asthma through an IL-10-dependent mechanism. J. Clin. Invest. 2013. 123: 1216-1228.
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 1216-1228
-
-
Mays, L.E.1
Ammon-Treiber, S.2
Mothes, B.3
Alkhaled, M.4
Rottenberger, J.5
Muller-Hermelink, E.S.6
Grimm, M.7
-
162
-
-
78649847380
-
Cell-permeable Foxp3 protein alleviates autoimmune disease associated with inflammatory bowel disease and allergic airway inflammation
-
Choi, J. M., Shin, J. H., Sohn, M. H., Harding, M. J., Park, J. H., Tobiasova, Z., Kim, D. Y. et al., Cell-permeable Foxp3 protein alleviates autoimmune disease associated with inflammatory bowel disease and allergic airway inflammation. Proc. Natl. Acad. Sci. USA 2010. 107: 18575-18580.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 18575-18580
-
-
Choi, J.M.1
Shin, J.H.2
Sohn, M.H.3
Harding, M.J.4
Park, J.H.5
Tobiasova, Z.6
Kim, D.Y.7
-
163
-
-
84860698476
-
Therapies for allergic inflammation: refining strategies to induce tolerance
-
Akdis, C. A., Therapies for allergic inflammation: refining strategies to induce tolerance. Nat. Med. 2012. 18: 736-749.
-
(2012)
Nat. Med.
, vol.18
, pp. 736-749
-
-
Akdis, C.A.1
|