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Volumn 8, Issue 3, 2012, Pages 131-132

Diabetes: Insulin signal meets SIRT1 at AKT

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; PROTEIN KINASE B; SIRT1 PROTEIN, HUMAN; SIRTUIN 1;

EID: 84865139517     PISSN: 17595029     EISSN: 17595037     Source Type: Journal    
DOI: 10.1038/nrendo.2011.208     Document Type: Article
Times cited : (10)

References (9)
  • 1
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    • Hepatic Sirtl deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance
    • Wang, R. H. et al. Hepatic Sirtl deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance. J. Clin. Invest. 121, 4477-4490 (2011).
    • (2011) J. Clin. Invest , vol.121 , pp. 4477-4490
    • Wang, R.H.1
  • 2
    • 33645860825 scopus 로고    scopus 로고
    • Reactive oxygen species have a causal role in multiple forms of insulin resistance
    • Houstis, N., Rosen, E. D. and Lander, E. S. Reactive oxygen species have a causal role in multiple forms of insulin resistance. Nature 440, 944-948 (2006).
    • (2006) Nature , vol.440 , pp. 944-948
    • Houstis, N.1    Rosen, E.D.2    Lander, E.S.3
  • 3
    • 14544282413 scopus 로고    scopus 로고
    • Nutrient control of glucose homeostasis through a complex of PGC-lalpha and SIRT1
    • Rodgers, J. T. et al. Nutrient control of glucose homeostasis through a complex of PGC-lalpha and SIRT1. Nature 434, 113-118 (2005).
    • (2005) Nature , vol.434 , pp. 113-118
    • Rodgers, J.T.1
  • 4
    • 56249100986 scopus 로고    scopus 로고
    • A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange
    • Liu, Y et al. A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange. Nature 456, 269-273 (2008).
    • (2008) Nature , vol.456 , pp. 269-273
    • Liu, Y.1
  • 5
    • 79960620082 scopus 로고    scopus 로고
    • The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy
    • Sundaresan, N. R. et al. The deacetylase SIRT1 promotes membrane localization and activation of Akt and PDK1 during tumorigenesis and cardiac hypertrophy. Sci. Signal. 4, ra46 (2011).
    • (2011) Sci. Signal. , vol.4
    • Sundaresan, N.R.1
  • 6
    • 80555142897 scopus 로고    scopus 로고
    • Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction
    • Schenk, S. et al. Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction. J. Clin. Invest. 121, 4281-4288 (2011).
    • (2011) J. Clin. Invest , vol.121 , pp. 4281-4288
    • Schenk, S.1
  • 7
    • 80053920774 scopus 로고    scopus 로고
    • Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice
    • Yoshino, J., Mills, K. F., Yoon, M. J. and Imai, S. Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 14, 528-536 (2011).
    • (2011) Cell Metab , vol.14 , pp. 528-536
    • Yoshino, J.1    Mills, K.F.2    Yoon, M.J.3    Imai, S.4
  • 8
    • 34548857700 scopus 로고    scopus 로고
    • SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B
    • Sun, C. et al. SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B. Cell Metab. 6, 307-319 (2007).
    • (2007) Cell Metab , vol.6 , pp. 307-319
    • Sun, C.1
  • 9
    • 36749087548 scopus 로고    scopus 로고
    • Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
    • Milne, J. C. et al. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature 450, 712-716 (2007).
    • (2007) Nature , vol.450 , pp. 712-716
    • Milne, J.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.