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Volumn 23, Issue , 2014, Pages 22-33

Systematic metabolic engineering of Escherichia coli for high-yield production of fuel bio-chemical 2,3-butanediol

Author keywords

2,3 Butanediol; Biofuel; Escherichia coli; Fermentation; Metabolic engineering; Promoter

Indexed keywords

2 ,3-BUTANEDIOL; BACILLUS LICHENIFORMIS; BIOSYNTHESIS GENE CLUSTER; EXTRACELLULAR METABOLITES; FED-BATCH FERMENTATION; FERMENTATION CONDITIONS; PROMOTER; RECOMBINANT ESCHERICHIA COLI;

EID: 84896847314     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2014.02.004     Document Type: Article
Times cited : (140)

References (62)
  • 3
    • 79958177780 scopus 로고    scopus 로고
    • High-flux isobutanol production using engineered Escherichia coli: a bioreactor study with in situ product removal
    • Baez A., Cho K.M., Liao J.C. High-flux isobutanol production using engineered Escherichia coli: a bioreactor study with in situ product removal. Appl. Microbiol. Biotechnol. 2011, 90:1681-1690.
    • (2011) Appl. Microbiol. Biotechnol. , vol.90 , pp. 1681-1690
    • Baez, A.1    Cho, K.M.2    Liao, J.C.3
  • 7
    • 70349759561 scopus 로고    scopus 로고
    • Biotechnological production of 2,3-butanediol - current state and prospects
    • Celińska E., Grajek W. Biotechnological production of 2,3-butanediol - current state and prospects. Biotechnol. Adv. 2009, 27:715-725.
    • (2009) Biotechnol. Adv. , vol.27 , pp. 715-725
    • Celińska, E.1    Grajek, W.2
  • 8
    • 0034536362 scopus 로고    scopus 로고
    • An investigation into the pathogenic properties of Escherichia coli strains BLR, BL21, DH5alpha and EQ1
    • Chart H., Smith H.R., La Ragione R.M., Woodward M.J. An investigation into the pathogenic properties of Escherichia coli strains BLR, BL21, DH5alpha and EQ1. J. Appl. Microbiol. 2000, 89:1048-1058.
    • (2000) J. Appl. Microbiol. , vol.89 , pp. 1048-1058
    • Chart, H.1    Smith, H.R.2    La Ragione, R.M.3    Woodward, M.J.4
  • 9
    • 77957343168 scopus 로고    scopus 로고
    • Cultivation, photobioreactor design and harvesting of microalgae for biodiesel production: a critical review
    • Chen C.Y., Yeh K.L., Aisyah R., Lee D.J., Chang J.S. Cultivation, photobioreactor design and harvesting of microalgae for biodiesel production: a critical review. Bioresour. Technol 2011, 102:71-81.
    • (2011) Bioresour. Technol , vol.102 , pp. 71-81
    • Chen, C.Y.1    Yeh, K.L.2    Aisyah, R.3    Lee, D.J.4    Chang, J.S.5
  • 11
    • 0020649604 scopus 로고
    • The tac promoter: a functional hybrid derived from the trp and lac promoters
    • U.S.A.
    • de Boer, H.A., Comstock, L.J., Vasser, M., 1983. The tac promoter: a functional hybrid derived from the trp and lac promoters. Proc. Natl. Acad. Sci. U.S.A. 80, pp. 21-25.
    • (1983) Proc. Natl. Acad. Sci. , vol.80 , pp. 21-25
    • de Boer, H.A.1    Comstock, L.J.2    Vasser, M.3
  • 12
    • 79955619779 scopus 로고    scopus 로고
    • Recent developments in the biotechnological production of hydrocarbons: paving the way for bio-based platform chemicals
    • Domínguez, de María P. Recent developments in the biotechnological production of hydrocarbons: paving the way for bio-based platform chemicals. ChemSusChem 2011, 4:327-329.
    • (2011) ChemSusChem , vol.4 , pp. 327-329
    • de María, D.P.1
  • 14
    • 0022870839 scopus 로고
    • Molecular cloning of the plasmid RP4 primase region in a multi-host-range tacP expression vector
    • Fürste J.P., Pansegrau W., Frank R., Blöcker H., Scholz P., Bagdasarian M., Lanka E. Molecular cloning of the plasmid RP4 primase region in a multi-host-range tacP expression vector. Gene 1986, 48:119-131.
    • (1986) Gene , vol.48 , pp. 119-131
    • Fürste, J.P.1    Pansegrau, W.2    Frank, R.3    Blöcker, H.4    Scholz, P.5    Bagdasarian, M.6    Lanka, E.7
  • 15
    • 84857269144 scopus 로고    scopus 로고
    • Looking for alternative energy sources
    • Gross M. Looking for alternative energy sources. Curr. Biol. 2012, 22:R103-106.
    • (2012) Curr. Biol. , vol.22
    • Gross, M.1
  • 16
    • 84872042531 scopus 로고    scopus 로고
    • Synthesis and characterization of novel renewable polyesters based on 2,5-furandicarboxylic acid and 2,3-butanediol
    • Gubbels E., Jasinska-Walc L., Koning C.E. Synthesis and characterization of novel renewable polyesters based on 2,5-furandicarboxylic acid and 2,3-butanediol. J. Polym. Sci 2012, 51:890-898.
    • (2012) J. Polym. Sci , vol.51 , pp. 890-898
    • Gubbels, E.1    Jasinska-Walc, L.2    Koning, C.E.3
  • 19
    • 0013914280 scopus 로고
    • Mutants of Escherichia coli K-12 defective in DNA repair and in genetic recombination
    • Howard-Flanders P., Theriot L. Mutants of Escherichia coli K-12 defective in DNA repair and in genetic recombination. Genetics 1966, 53:1137-1150.
    • (1966) Genetics , vol.53 , pp. 1137-1150
    • Howard-Flanders, P.1    Theriot, L.2
  • 20
    • 79952694448 scopus 로고    scopus 로고
    • Microbial 2,3-butanediol production: a state-of-the-art review
    • Ji X.J., Huang H., Ouyang P.K. Microbial 2,3-butanediol production: a state-of-the-art review. Biotechnol. Adv. 2011, 29:351-364.
    • (2011) Biotechnol. Adv. , vol.29 , pp. 351-364
    • Ji, X.J.1    Huang, H.2    Ouyang, P.K.3
  • 21
    • 84859772410 scopus 로고    scopus 로고
    • Synthetic biology and the development of tools for metabolic engineering
    • Keasling J.D. Synthetic biology and the development of tools for metabolic engineering. Metab. Eng. 2012, 14:189-195.
    • (2012) Metab. Eng. , vol.14 , pp. 189-195
    • Keasling, J.D.1
  • 22
    • 78649716727 scopus 로고    scopus 로고
    • Manufacturing molecules through metabolic engineering
    • Keasling J.D. Manufacturing molecules through metabolic engineering. Science 2010, 330:1355-1358.
    • (2010) Science , vol.330 , pp. 1355-1358
    • Keasling, J.D.1
  • 23
    • 84879111205 scopus 로고    scopus 로고
    • Metabolic engineering of a novel Klebsiella oxytoca strain for enhanced 2,3-butanediol production
    • Kim D.K., Rathnasingh C., Song H., Lee H.J., Seung D., Chang Y.K. Metabolic engineering of a novel Klebsiella oxytoca strain for enhanced 2,3-butanediol production. J. Biosci. Bioeng. 2013, 116:186-192.
    • (2013) J. Biosci. Bioeng. , vol.116 , pp. 186-192
    • Kim, D.K.1    Rathnasingh, C.2    Song, H.3    Lee, H.J.4    Seung, D.5    Chang, Y.K.6
  • 24
    • 84882274841 scopus 로고    scopus 로고
    • Production of 2,3-butanediol by engineered Saccharomyces cerevisiae
    • Kim S.J., Seo S.O., Jin Y.S., Seo J.H. Production of 2,3-butanediol by engineered Saccharomyces cerevisiae. Bioresour. Technol. 2013, 146:274-281.
    • (2013) Bioresour. Technol. , vol.146 , pp. 274-281
    • Kim, S.J.1    Seo, S.O.2    Jin, Y.S.3    Seo, J.H.4
  • 26
    • 0020086275 scopus 로고
    • DNA sequences affecting specific initiation of transcription in vitro from the EIII promoter of adenovirus 2
    • Lee, D.C., Roeder, R.G., Wold, W.S., 1982. DNA sequences affecting specific initiation of transcription in vitro from the EIII promoter of adenovirus 2. Proc. Natl. Acad. Sci. U.S.A. 79, pp. 41-45.
    • (1982) Proc. Natl. Acad. Sci. U.S.A. , vol.79 , pp. 41-45
    • Lee, D.C.1    Roeder, R.G.2    Wold, W.S.3
  • 27
    • 84862802719 scopus 로고    scopus 로고
    • Synthesis of pure meso-2,3-butanediol from crude glycerol using an engineered metabolic pathway in Escherichia coli
    • Lee S., Kim B., Park K., Um Y., Lee J. Synthesis of pure meso-2,3-butanediol from crude glycerol using an engineered metabolic pathway in Escherichia coli. Appl. Biochem. Biotechnol. 2012, 166:1801-1813.
    • (2012) Appl. Biochem. Biotechnol. , vol.166 , pp. 1801-1813
    • Lee, S.1    Kim, B.2    Park, K.3    Um, Y.4    Lee, J.5
  • 28
    • 84866326630 scopus 로고    scopus 로고
    • Genome sequences of two thermophilic Bacillus licheniformis strains, efficient producers of platform chemical 2,3-butanediol
    • Li L., Su F., Wang Y., Zhang L., Liu C., Li J., Ma C., Xu P. Genome sequences of two thermophilic Bacillus licheniformis strains, efficient producers of platform chemical 2,3-butanediol. J. Bacteriol. 2012, 194:4133-4134.
    • (2012) J. Bacteriol. , vol.194 , pp. 4133-4134
    • Li, L.1    Su, F.2    Wang, Y.3    Zhang, L.4    Liu, C.5    Li, J.6    Ma, C.7    Xu, P.8
  • 29
    • 84857098244 scopus 로고    scopus 로고
    • Biocatalytic production of (2S,3S)-2,3-butanediol from diacetyl using whole cells of engineered Escherichia coli
    • Li L., Wang Y., Zhang L., Ma C., Wang A., Tao F., Xu P. Biocatalytic production of (2S,3S)-2,3-butanediol from diacetyl using whole cells of engineered Escherichia coli. Bioresour. Technol. 2012, 115:111-116.
    • (2012) Bioresour. Technol. , vol.115 , pp. 111-116
    • Li, L.1    Wang, Y.2    Zhang, L.3    Ma, C.4    Wang, A.5    Tao, F.6    Xu, P.7
  • 30
    • 84883063294 scopus 로고    scopus 로고
    • A newly isolated Bacillus licheniformis strain thermophilically produces 2,3-butanediol, a platform and fuel bio-chemical
    • Li L., Zhang L., Li K., Wang Y., Gao C., Han B., Ma C., Xu P. A newly isolated Bacillus licheniformis strain thermophilically produces 2,3-butanediol, a platform and fuel bio-chemical. Biotechnol. Biofuels 2013, 6:123.
    • (2013) Biotechnol. Biofuels , vol.6 , pp. 123
    • Li, L.1    Zhang, L.2    Li, K.3    Wang, Y.4    Gao, C.5    Han, B.6    Ma, C.7    Xu, P.8
  • 31
    • 77955559433 scopus 로고    scopus 로고
    • Microbial production of meso-2,3-butanediol by metabolically engineered Escherichia coli under low oxygen condition
    • Li Z.J., Jian J., Wei X.X., Shen X.W., Chen G.Q. Microbial production of meso-2,3-butanediol by metabolically engineered Escherichia coli under low oxygen condition. Appl. Microbiol. Biotechnol. 2010, 87:2001-2009.
    • (2010) Appl. Microbiol. Biotechnol. , vol.87 , pp. 2001-2009
    • Li, Z.J.1    Jian, J.2    Wei, X.X.3    Shen, X.W.4    Chen, G.Q.5
  • 34
    • 84876300746 scopus 로고    scopus 로고
    • Microbial production of 2,3-butanediol from seaweed hydrolysate using metabolically engineered Escherichia coli
    • Mazumdar S., Lee J., Oh M.K. Microbial production of 2,3-butanediol from seaweed hydrolysate using metabolically engineered Escherichia coli. Bioresour. Technol. 2013, 136:329-336.
    • (2013) Bioresour. Technol. , vol.136 , pp. 329-336
    • Mazumdar, S.1    Lee, J.2    Oh, M.K.3
  • 36
    • 77949448789 scopus 로고    scopus 로고
    • Metabolic engineering of acetoin and meso-2,3-butanediol biosynthesis in E. coli
    • Nielsen D.R., Yoon S.H., Yuan C.J., Prather K.L. Metabolic engineering of acetoin and meso-2,3-butanediol biosynthesis in E. coli. Biotechnol. J. 2010, 5:274-284.
    • (2010) Biotechnol. J. , vol.5 , pp. 274-284
    • Nielsen, D.R.1    Yoon, S.H.2    Yuan, C.J.3    Prather, K.L.4
  • 38
    • 0023287585 scopus 로고
    • Simulations of host-plasmid interactions in Escherichia coli: Copy number, promoter strength, and ribosome binding site strength effects on metabolic activity and plasmid gene expression
    • Peretti S.W., Bailey J.E. Simulations of host-plasmid interactions in Escherichia coli: Copy number, promoter strength, and ribosome binding site strength effects on metabolic activity and plasmid gene expression. Biotechnol. Bioeng. 1987, 29:316-328.
    • (1987) Biotechnol. Bioeng. , vol.29 , pp. 316-328
    • Peretti, S.W.1    Bailey, J.E.2
  • 39
    • 0028169895 scopus 로고
    • Purification and properties of the alpha-acetolactate decarboxylase from Lactococcus lactis subsp. lactis NCDO 2118
    • Phalip V., Monnet C., Schmitt P., Renault P., Godon J.J., Diviès C. Purification and properties of the alpha-acetolactate decarboxylase from Lactococcus lactis subsp. lactis NCDO 2118. FEBS Lett. 1994, 351:95-99.
    • (1994) FEBS Lett. , vol.351 , pp. 95-99
    • Phalip, V.1    Monnet, C.2    Schmitt, P.3    Renault, P.4    Godon, J.J.5    Diviès, C.6
  • 41
    • 0034740227 scopus 로고    scopus 로고
    • Application of a time-delay neural network to promoter annotation in the Drosophila melanogaster genome
    • Reese M.G. Application of a time-delay neural network to promoter annotation in the Drosophila melanogaster genome. Comput. Chem. 2001, 26:51-56.
    • (2001) Comput. Chem. , vol.26 , pp. 51-56
    • Reese, M.G.1
  • 42
    • 0027167447 scopus 로고
    • Regulation of the Bacillus subtilis alsS, alsD, and alsR genes involved in post-exponential-phase production of acetoin
    • Renna M.C., Najimudin N., Winik L.R., Zahler S.A. Regulation of the Bacillus subtilis alsS, alsD, and alsR genes involved in post-exponential-phase production of acetoin. J. Bacteriol. 1993, 175:3863-3875.
    • (1993) J. Bacteriol. , vol.175 , pp. 3863-3875
    • Renna, M.C.1    Najimudin, N.2    Winik, L.R.3    Zahler, S.A.4
  • 44
    • 84862262515 scopus 로고    scopus 로고
    • High-yield production of meso-2,3-butanediol from cellodextrin by engineered E. coli biocatalysts
    • Shin H.D., Yoon S.H., Wu J., Rutter C., Kim S.W., Chen R.R. High-yield production of meso-2,3-butanediol from cellodextrin by engineered E. coli biocatalysts. Bioresour. Technol. 2012, 118:367-373.
    • (2012) Bioresour. Technol. , vol.118 , pp. 367-373
    • Shin, H.D.1    Yoon, S.H.2    Wu, J.3    Rutter, C.4    Kim, S.W.5    Chen, R.R.6
  • 45
    • 77953880857 scopus 로고    scopus 로고
    • Valine 375 and phenylalanine 109 confer affinity and specificity for pyruvate as donor substrate in acetohydroxy acid synthase isozyme II from Escherichia coli
    • Steinmetz A., Vyazmensky M., Meyer D., Barak Z.E., Golbik R., Chipman D.M., Tittmann K. Valine 375 and phenylalanine 109 confer affinity and specificity for pyruvate as donor substrate in acetohydroxy acid synthase isozyme II from Escherichia coli. Biochemistry 2010, 49:5188-5199.
    • (2010) Biochemistry , vol.49 , pp. 5188-5199
    • Steinmetz, A.1    Vyazmensky, M.2    Meyer, D.3    Barak, Z.E.4    Golbik, R.5    Chipman, D.M.6    Tittmann, K.7
  • 46
    • 0016419156 scopus 로고
    • 2,3-Butanediol biosynthetic system in Aerobacter aerogenes
    • Stormer F.C. 2,3-Butanediol biosynthetic system in Aerobacter aerogenes. Methods Enzymol. 1975, 41:518-532.
    • (1975) Methods Enzymol. , vol.41 , pp. 518-532
    • Stormer, F.C.1
  • 47
    • 0026604468 scopus 로고
    • Conversion of pyruvate to acetoin helps to maintain pH homeostasis in Lactobacillus plantarum
    • Tsau J.L., Guffanti A.A., Montville T.J. Conversion of pyruvate to acetoin helps to maintain pH homeostasis in Lactobacillus plantarum. Appl. Environ. Microbiol. 1992, 58:891-894.
    • (1992) Appl. Environ. Microbiol. , vol.58 , pp. 891-894
    • Tsau, J.L.1    Guffanti, A.A.2    Montville, T.J.3
  • 48
    • 0343924603 scopus 로고    scopus 로고
    • Molecular generation of an Escherichia coli strain producing only the meso-isomer of 2,3-butanediol
    • Ui S., Okajima Y., Mimura1 A., Kanai H., Kudo T. Molecular generation of an Escherichia coli strain producing only the meso-isomer of 2,3-butanediol. J. Ferment. Bioeng. 1997, 84:185-189.
    • (1997) J. Ferment. Bioeng. , vol.84 , pp. 185-189
    • Ui, S.1    Okajima, Y.2    Mimura1, A.3    Kanai, H.4    Kudo, T.5
  • 49
    • 84863609980 scopus 로고    scopus 로고
    • Efficient 2,3-butanediol production from cassava powder by a crop-biomass-utilizer, Enterobacter cloacae subsp. dissolvens SDM
    • Wang A., Xu Y., Ma C., Gao C., Li L., Wang Y., Tao F., Xu P. Efficient 2,3-butanediol production from cassava powder by a crop-biomass-utilizer, Enterobacter cloacae subsp. dissolvens SDM. PLoS One 2012, 7:e40442.
    • (2012) PLoS One , vol.7
    • Wang, A.1    Xu, Y.2    Ma, C.3    Gao, C.4    Li, L.5    Wang, Y.6    Tao, F.7    Xu, P.8
  • 51
    • 84870413115 scopus 로고    scopus 로고
    • Thermophilic fermentation of acetoin and 2,3-butanediol by a novel Geobacillus strain
    • Xiao Z., Wang X., Huang Y., Huo F., Zhu X., Xi L., Lu J.R. Thermophilic fermentation of acetoin and 2,3-butanediol by a novel Geobacillus strain. Biotechnol. Biofuels 2012, 5:88.
    • (2012) Biotechnol. Biofuels , vol.5 , pp. 88
    • Xiao, Z.1    Wang, X.2    Huang, Y.3    Huo, F.4    Zhu, X.5    Xi, L.6    Lu, J.R.7
  • 52
    • 34548497884 scopus 로고    scopus 로고
    • Molecular characterization of class 3 integrons from Delftia spp
    • Xu H., Davies J., Miao V. Molecular characterization of class 3 integrons from Delftia spp. J. Bacteriol. 2007, 189:6276-6283.
    • (2007) J. Bacteriol. , vol.189 , pp. 6276-6283
    • Xu, H.1    Davies, J.2    Miao, V.3
  • 53
    • 84876206509 scopus 로고    scopus 로고
    • New Constitutive vectors: useful genetic engineering tools for biocatalysis
    • Xu Y., Tao F., Ma C., Xu P. New Constitutive vectors: useful genetic engineering tools for biocatalysis. Appl. Environ. Microbiol. 2013, 79:2836-2840.
    • (2013) Appl. Environ. Microbiol. , vol.79 , pp. 2836-2840
    • Xu, Y.1    Tao, F.2    Ma, C.3    Xu, P.4
  • 54
    • 84863152203 scopus 로고    scopus 로고
    • Genome sequence of Enterobacter cloacae subsp. dissolvens SDM, an efficient biomass-utilizing producer of platform chemical 2,3-butanediol
    • Xu Y., Wang A., Tao F., Su F., Tang H., Ma C., Xu P. Genome sequence of Enterobacter cloacae subsp. dissolvens SDM, an efficient biomass-utilizing producer of platform chemical 2,3-butanediol. J. Bacteriol. 2012, 194:897-898.
    • (2012) J. Bacteriol. , vol.194 , pp. 897-898
    • Xu, Y.1    Wang, A.2    Tao, F.3    Su, F.4    Tang, H.5    Ma, C.6    Xu, P.7
  • 56
    • 84887082226 scopus 로고    scopus 로고
    • Effects of corn steep liquor on production of 2,3-butanediol and acetoin by Bacillus subtilis
    • Yang T.W., Rao Z.M., Zhang X., Xu M.J., Xu Z.H., Yang S.T. Effects of corn steep liquor on production of 2,3-butanediol and acetoin by Bacillus subtilis. Process Biochem. 2013, 48:1610-1617.
    • (2013) Process Biochem. , vol.48 , pp. 1610-1617
    • Yang, T.W.1    Rao, Z.M.2    Zhang, X.3    Xu, M.J.4    Xu, Z.H.5    Yang, S.T.6
  • 57
    • 0031923093 scopus 로고    scopus 로고
    • Isolation and characterization of ethanol-tolerant mutants of Escherichia coli KO11 for fuel ethanol production
    • Yomano L.P., York S.W., Ingram L.O. Isolation and characterization of ethanol-tolerant mutants of Escherichia coli KO11 for fuel ethanol production. J. Ind. Microbiol. Biotechnol. 1998, 20:132-138.
    • (1998) J. Ind. Microbiol. Biotechnol. , vol.20 , pp. 132-138
    • Yomano, L.P.1    York, S.W.2    Ingram, L.O.3
  • 58
    • 82755161073 scopus 로고    scopus 로고
    • Microbial production of diols as platform chemicals: recent progresses
    • Zeng A.P., Sabra W. Microbial production of diols as platform chemicals: recent progresses. Curr. Opin. Biotechnol. 2011, 22:749-757.
    • (2011) Curr. Opin. Biotechnol. , vol.22 , pp. 749-757
    • Zeng, A.P.1    Sabra, W.2
  • 59
    • 84865600352 scopus 로고    scopus 로고
    • Metabolic engineering of Escherichia coli BL21 for biosynthesis of heparosan, a bioengineered heparin precursor
    • Zhang C., Liu L., Teng L., Chen J., Liu J., Li J., Du G., Chen J. Metabolic engineering of Escherichia coli BL21 for biosynthesis of heparosan, a bioengineered heparin precursor. Metab. Eng. 2012, 14:521-527.
    • (2012) Metab. Eng. , vol.14 , pp. 521-527
    • Zhang, C.1    Liu, L.2    Teng, L.3    Chen, J.4    Liu, J.5    Li, J.6    Du, G.7    Chen, J.8
  • 60
    • 84898850188 scopus 로고    scopus 로고
    • A new NAD(H)-dependent meso-2,3-butanediol dehydrogenase from an industrially potential strain Serratia marcescens H30
    • Zhang L., Xu Q., Zhan S., Li Y., Lin H., Sun S., Sha L., Hu K., Guan X., Shen Y. A new NAD(H)-dependent meso-2,3-butanediol dehydrogenase from an industrially potential strain Serratia marcescens H30. Appl. Microbiol. Biotechnol. 2013, 10.1007/s00253-013-4959-x.
    • (2013) Appl. Microbiol. Biotechnol.
    • Zhang, L.1    Xu, Q.2    Zhan, S.3    Li, Y.4    Lin, H.5    Sun, S.6    Sha, L.7    Hu, K.8    Guan, X.9    Shen, Y.10
  • 61
    • 84876673237 scopus 로고    scopus 로고
    • Metabolic engineering of Escherichia coli for high-specificity production of isoprenol and prenol as next generation of biofuels
    • Zheng Y., Liu Q., Li L., Qin W., Yang J., Zhang H., Jiang X., Cheng T., Liu W., Xu X., Xian M. Metabolic engineering of Escherichia coli for high-specificity production of isoprenol and prenol as next generation of biofuels. Biotechnol. Biofuels 2013, 6:57.
    • (2013) Biotechnol. Biofuels , vol.6 , pp. 57
    • Zheng, Y.1    Liu, Q.2    Li, L.3    Qin, W.4    Yang, J.5    Zhang, H.6    Jiang, X.7    Cheng, T.8    Liu, W.9    Xu, X.10    Xian, M.11
  • 62
    • 84861142495 scopus 로고    scopus 로고
    • Optimization of fatty alcohol biosynthesis pathway for selectively enhanced production of C12/14 and C16/18 fatty alcohols in engineered Escherichia coli
    • Zheng Y.N., Li L.L., Liu Q., Yang J.M., Wang X.W., Liu W., Xu X., Liu H., Zhao G., Xian M. Optimization of fatty alcohol biosynthesis pathway for selectively enhanced production of C12/14 and C16/18 fatty alcohols in engineered Escherichia coli. Microb. Cell. Fact. 2012, 11:65.
    • (2012) Microb. Cell. Fact. , vol.11 , pp. 65
    • Zheng, Y.N.1    Li, L.L.2    Liu, Q.3    Yang, J.M.4    Wang, X.W.5    Liu, W.6    Xu, X.7    Liu, H.8    Zhao, G.9    Xian, M.10


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