MUC1-C nuclear localization drives invasiveness of renal cancer cells through a sheddase/gamma secretase dependent pathway

Oncotarget

Volumn 5, Issue 3, 2014, Pages 754-763

  Bouillez, Audrey ^a   Gnemmi, Viviane ^a,b,c   Gaudelot, Kelly ^a   Hémon, Brigitte ^a   Ringot, Bélinda ^a   Pottier, Nicolas ^b,d   Glowacki, François ^c,d   Butruille, Caroline ^c   Cauffiez, Christelle ^b,d   Hamdane, Malika ^a   Sergeant, Nicolas ^a   Van Seuningen, Isabelle ^a   Leroy, Xavier ^a,b,c   Aubert, Sébastien ^a,b,c   Perrais, Michaël ^a,b  

^a JEAN PIERRE AUBERT RESEARCH CENTER   (France)

^b UNIV LILLE   (France)

^c LILLE UNIVERSITY HOSPITAL   (France)

^d UFR3S Pharmacie   (France)

Author keywords

ADAM10; ADAM17; Invasion; Kidney cancer; MUC1; Y secretase

Indexed keywords

ADAM10 ENDOPEPTIDASE; GAMMA SECRETASE; MUCIN 1; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; MUC1 PROTEIN, HUMAN; PROTEIN SUBUNIT; SECRETASE;

ARTICLE; CANCER CELL; CANCER GROWTH; CARCINOGENESIS; CELL AGGREGATION; CELL MIGRATION; CELL VIABILITY; CYTOPLASM; KIDNEY CANCER; METASTASIS; NUCLEAR LOCALIZATION SIGNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; TUMOR INVASION; ANIMAL; CELL NUCLEUS; DISEASE COURSE; GENETIC TRANSFECTION; GENETICS; HUMAN; KIDNEY TUMOR; METABOLISM; MOUSE; PATHOLOGY; PROTEIN SUBUNIT; SCID MOUSE; SIGNAL TRANSDUCTION; TUMOR CELL LINE; XENOGRAFT;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; CELL LINE, TUMOR; CELL NUCLEUS; DISEASE PROGRESSION; HETEROGRAFTS; HUMANS; KIDNEY NEOPLASMS; MICE; MICE, SCID; MUCIN-1; PROTEIN SUBUNITS; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84896823781     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1768     Document Type: Article

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