메뉴 건너뛰기




Volumn 6, Issue 4, 2008, Pages 555-567

MUC1 initiates Src-CrkL-Rac1/Cdc42-mediated actin cytoskeletal protrusive motility after ligating intercellular adhesion molecule-1

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CRK LIKE PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MUCIN 1; PROTEIN CDC42; PROTEIN TYROSINE KINASE; RAC1 PROTEIN;

EID: 42049108198     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-07-2033     Document Type: Article
Times cited : (63)

References (46)
  • 1
    • 0026631262 scopus 로고
    • Spatial and temporal expression of an epithelial mucin, Muc-1, during mouse development
    • Braga VM, Pemberton LF, Duhig T, Gendler SJ. Spatial and temporal expression of an epithelial mucin, Muc-1, during mouse development. Development 1992;115:427-37.
    • (1992) Development , vol.115 , pp. 427-437
    • Braga, V.M.1    Pemberton, L.F.2    Duhig, T.3    Gendler, S.J.4
  • 2
    • 0030070154 scopus 로고    scopus 로고
    • The epithelial mucin MUC1 contains at least two discrete signals specifying membrane localization in cells
    • Pemberton LF, Rughetti A, Taylor-Papadimitriou J, Gendler SJ. The epithelial mucin MUC1 contains at least two discrete signals specifying membrane localization in cells. J Biol Chem 1996;271:2332-40.
    • (1996) J Biol Chem , vol.271 , pp. 2332-2340
    • Pemberton, L.F.1    Rughetti, A.2    Taylor-Papadimitriou, J.3    Gendler, S.J.4
  • 3
    • 0021740104 scopus 로고
    • Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors
    • Kufe D, Inghirami G, Abe M, Hayes D, Justi-Wheeler H, Schlom J. Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors. Hybridoma 1984;3:223-32.
    • (1984) Hybridoma , vol.3 , pp. 223-232
    • Kufe, D.1    Inghirami, G.2    Abe, M.3    Hayes, D.4    Justi-Wheeler, H.5    Schlom, J.6
  • 4
    • 0035370711 scopus 로고    scopus 로고
    • The importance of MUC1 cellular localization in patients with breast carcinoma: An immunohistologic study of 71 patients and review of the literature
    • Rahn JJ, Dabbagh L, Pasdar M, Hugh JC. The importance of MUC1 cellular localization in patients with breast carcinoma: an immunohistologic study of 71 patients and review of the literature. Cancer 2001;91:1973-82.
    • (2001) Cancer , vol.91 , pp. 1973-1982
    • Rahn, J.J.1    Dabbagh, L.2    Pasdar, M.3    Hugh, J.C.4
  • 5
    • 0032403072 scopus 로고    scopus 로고
    • MUC1 synthetic peptide inhibition of intercellular adhesion molecule-1 and MUC1 binding requires six tandem repeats
    • Kam JL, Regimbald LH, Hilgers JH, et al. MUC1 synthetic peptide inhibition of intercellular adhesion molecule-1 and MUC1 binding requires six tandem repeats. Cancer Res 1998;58:5577-81.
    • (1998) Cancer Res , vol.58 , pp. 5577-5581
    • Kam, J.L.1    Regimbald, L.H.2    Hilgers, J.H.3
  • 6
    • 0029664850 scopus 로고    scopus 로고
    • The breast mucin MUCI as a novel adhesion ligand for endothelial intercellular adhesion molecule 1 in breast cancer
    • Regimbald LH, Pilarski LM, Longenecker BM, Reddish MA, Zimmermann G, Hugh JC. The breast mucin MUCI as a novel adhesion ligand for endothelial intercellular adhesion molecule 1 in breast cancer. Cancer Res 1996;56:4244-9.
    • (1996) Cancer Res , vol.56 , pp. 4244-4249
    • Regimbald, L.H.1    Pilarski, L.M.2    Longenecker, B.M.3    Reddish, M.A.4    Zimmermann, G.5    Hugh, J.C.6
  • 7
    • 0003167772 scopus 로고    scopus 로고
    • Leukocyte migration and inflammation
    • 3rd ed. New York: WH. Freeman;
    • Kuby J. Leukocyte migration and inflammation. Immunology. 3rd ed. New York: WH. Freeman; 1997. p. 361-77.
    • (1997) Immunology , pp. 361-377
    • Kuby, J.1
  • 8
    • 28644443714 scopus 로고    scopus 로고
    • MUC1 mediates transendothelial migration in vitro by ligating endothelial cell ICAM-1
    • Rahn JJ, Chow JW, Horne GJ, et al. MUC1 mediates transendothelial migration in vitro by ligating endothelial cell ICAM-1. Clin Exp Metastasis 2005;22:475-83.
    • (2005) Clin Exp Metastasis , vol.22 , pp. 475-483
    • Rahn, J.J.1    Chow, J.W.2    Horne, G.J.3
  • 9
    • 0041736264 scopus 로고    scopus 로고
    • Continuous real time ex vivo epifluorescent video microscopy for the study of metastatic cancer cell interactions with microvascular endothelium
    • Glinskii OV, Huxley VH, Turk JR, et al. Continuous real time ex vivo epifluorescent video microscopy for the study of metastatic cancer cell interactions with microvascular endothelium. Clin Exp Metastasis 2003;20:451-8.
    • (2003) Clin Exp Metastasis , vol.20 , pp. 451-458
    • Glinskii, O.V.1    Huxley, V.H.2    Turk, J.R.3
  • 10
    • 0038418255 scopus 로고    scopus 로고
    • Intravascular metastatic cancer cell homotypic aggregation at the sites of primary attachment to the endothelium
    • Glinsky VV, Glinsky GV, Glinskii OV, et al. Intravascular metastatic cancer cell homotypic aggregation at the sites of primary attachment to the endothelium. Cancer Res 2003;63:3805-11.
    • (2003) Cancer Res , vol.63 , pp. 3805-3811
    • Glinsky, V.V.1    Glinsky, G.V.2    Glinskii, O.V.3
  • 11
    • 0035132742 scopus 로고    scopus 로고
    • MUC1 mucin core protein binds to the domain 1 of ICAM-1
    • Hayashi T, Takahashi T, Motoya S, et al. MUC1 mucin core protein binds to the domain 1 of ICAM-1. Digestion 2001;63 Suppl 1:87-92.
    • (2001) Digestion , vol.63 , Issue.SUPPL. 1 , pp. 87-92
    • Hayashi, T.1    Takahashi, T.2    Motoya, S.3
  • 12
    • 0141459073 scopus 로고    scopus 로고
    • Identification of four sites of stimulated tyrosine phosphorylation in the MUC1 cytoplasmic tail
    • Wang H, Lillehoj EP, Kim KC. Identification of four sites of stimulated tyrosine phosphorylation in the MUC1 cytoplasmic tail. Biochem Biophys Res Commun 2003;310:341-6.
    • (2003) Biochem Biophys Res Commun , vol.310 , pp. 341-346
    • Wang, H.1    Lillehoj, E.P.2    Kim, K.C.3
  • 13
    • 0028148592 scopus 로고
    • Tyrosine phosphorylation of the MUC1 breast cancer membrane proteins. Cytokine receptor-like molecules
    • Zrihan-Licht S, Baruch A, Elroy-Stein O, Keydar I, Wreschner DH. Tyrosine phosphorylation of the MUC1 breast cancer membrane proteins. Cytokine receptor-like molecules. FEBS Lett 1994;356:130-6.
    • (1994) FEBS Lett , vol.356 , pp. 130-136
    • Zrihan-Licht, S.1    Baruch, A.2    Elroy-Stein, O.3    Keydar, I.4    Wreschner, D.H.5
  • 14
    • 0035929643 scopus 로고    scopus 로고
    • The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and β-catenin
    • Li Y, Ren J, Yu W, et al. The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and β-catenin. J Biol Chem 2001;276:35239-42.
    • (2001) J Biol Chem , vol.276 , pp. 35239-35242
    • Li, Y.1    Ren, J.2    Yu, W.3
  • 15
    • 0035918199 scopus 로고    scopus 로고
    • Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland
    • Schroeder JA, Thompson MC, Gardner MM, Gendler SJ. Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland. J Biol Chem 2001;276:13057-64.
    • (2001) J Biol Chem , vol.276 , pp. 13057-13064
    • Schroeder, J.A.1    Thompson, M.C.2    Gardner, M.M.3    Gendler, S.J.4
  • 16
    • 0037124099 scopus 로고    scopus 로고
    • Protein kinase C δ regulates function of the DF3/MUC1 carcinoma antigen in β-catenin signaling
    • Ren J, Li Y, Kufe D. Protein kinase C δ regulates function of the DF3/MUC1 carcinoma antigen in β-catenin signaling. J Biol Chem 2002;277:17616-22.
    • (2002) J Biol Chem , vol.277 , pp. 17616-17622
    • Ren, J.1    Li, Y.2    Kufe, D.3
  • 17
    • 0037053330 scopus 로고    scopus 로고
    • Tyrosine kinase c-Src constitutes a bridge between cystic fibrosis transmembrane regulator channel failure and MUC1 overexpression in cystic fibrosis
    • Gonzalez-Guerrico AM, Cafferata EG, Radrizzani M, et al. Tyrosine kinase c-Src constitutes a bridge between cystic fibrosis transmembrane regulator channel failure and MUC1 overexpression in cystic fibrosis. J Biol Chem 2002;277:17239-47.
    • (2002) J Biol Chem , vol.277 , pp. 17239-17247
    • Gonzalez-Guerrico, A.M.1    Cafferata, E.G.2    Radrizzani, M.3
  • 18
    • 0035794215 scopus 로고    scopus 로고
    • The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3 β and β-catenin
    • Li Y, Kuwahara H, Ren J, Wen G, Kufe D. The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3 β and β-catenin. J Biol Chem 2001;276:6061-4.
    • (2001) J Biol Chem , vol.276 , pp. 6061-6064
    • Li, Y.1    Kuwahara, H.2    Ren, J.3    Wen, G.4    Kufe, D.5
  • 19
    • 0028841813 scopus 로고
    • Involvement of the cell surface-bound mucin, episialin/MUC1, in progression of human carcinomas
    • Hilkens J, Wesseling J, Vos HL, et al. Involvement of the cell surface-bound mucin, episialin/MUC1, in progression of human carcinomas. Biochem Soc Trans 1995;23:822-6.
    • (1995) Biochem Soc Trans , vol.23 , pp. 822-826
    • Hilkens, J.1    Wesseling, J.2    Vos, H.L.3
  • 20
    • 3142776544 scopus 로고    scopus 로고
    • MUC1 initiates a calcium signal after ligation by intercellular adhesion molecule-1
    • Rahn JJ, Shen Q, Mah BK, Hugh JC. MUC1 initiates a calcium signal after ligation by intercellular adhesion molecule-1. J Biol Chem 2004;279:29386-90.
    • (2004) J Biol Chem , vol.279 , pp. 29386-29390
    • Rahn, J.J.1    Shen, Q.2    Mah, B.K.3    Hugh, J.C.4
  • 21
    • 0036056156 scopus 로고    scopus 로고
    • Cancer cell motility - on the road from c-erbB-2 receptor steered signaling to actin reorganization
    • Feldner JC, Brandt BH. Cancer cell motility - on the road from c-erbB-2 receptor steered signaling to actin reorganization. Exp Cell Res 2002;272:93-108.
    • (2002) Exp Cell Res , vol.272 , pp. 93-108
    • Feldner, J.C.1    Brandt, B.H.2
  • 23
    • 7944233251 scopus 로고    scopus 로고
    • The interplay between Src and integrins in normal and tumor biology
    • Playford MP, Schaller MD. The interplay between Src and integrins in normal and tumor biology. Oncogene 2004;23:7928-46.
    • (2004) Oncogene , vol.23 , pp. 7928-7946
    • Playford, M.P.1    Schaller, M.D.2
  • 24
    • 0032559362 scopus 로고    scopus 로고
    • GTPases and the actin cytoskeleton
    • Hall A. Rho GTPases and the actin cytoskeleton. Science 1998;279:509-14.
    • (1998) Science , vol.279 , pp. 509-514
    • Rho, H.A.1
  • 25
    • 0030968580 scopus 로고    scopus 로고
    • Rho GTPases and signaling networks
    • Van Aelst L, D'Souza-Schorey C. Rho GTPases and signaling networks. Genes Dev 1997;11:2295-322.
    • (1997) Genes Dev , vol.11 , pp. 2295-2322
    • Van Aelst, L.1    D'Souza-Schorey, C.2
  • 26
    • 0033594123 scopus 로고    scopus 로고
    • Rho GTPases control polarity, protrusion, and adhesion during cell movement
    • Nobes CD, Hall A. Rho GTPases control polarity, protrusion, and adhesion during cell movement. J Cell Biol 1999;144:1235-44.
    • (1999) J Cell Biol , vol.144 , pp. 1235-1244
    • Nobes, C.D.1    Hall, A.2
  • 27
    • 0033577975 scopus 로고    scopus 로고
    • Interplay between Rac and Rho in the control of substrate contact dynamics
    • Rottner K, Hall A, Small JV. Interplay between Rac and Rho in the control of substrate contact dynamics. Curr Biol 1999;9:640-8.
    • (1999) Curr Biol , vol.9 , pp. 640-648
    • Rottner, K.1    Hall, A.2    Small, J.V.3
  • 29
    • 7144263722 scopus 로고    scopus 로고
    • Development of highly selective SH3 binding peptides for Crk and CRKL which disrupt Crk-complexes with DOCK180, SoS and C3G
    • Posern G, Zheng J, Knudsen BS, et al. Development of highly selective SH3 binding peptides for Crk and CRKL which disrupt Crk-complexes with DOCK180, SoS and C3G. Oncogene 1998;16:1903-12.
    • (1998) Oncogene , vol.16 , pp. 1903-1912
    • Posern, G.1    Zheng, J.2    Knudsen, B.S.3
  • 30
    • 0344406976 scopus 로고    scopus 로고
    • Translocation of CrkL to focal adhesions mediates integrin-induced migration downstream of Src family kinases
    • Li L, Guris DL, Okura M, Imamoto A. Translocation of CrkL to focal adhesions mediates integrin-induced migration downstream of Src family kinases. Mol Cell Biol 2003;23:2883-92.
    • (2003) Mol Cell Biol , vol.23 , pp. 2883-2892
    • Li, L.1    Guris, D.L.2    Okura, M.3    Imamoto, A.4
  • 31
    • 16044366598 scopus 로고    scopus 로고
    • p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene
    • Salgia R, Pisick E, Sattler M, et al. p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene. J Biol Chem 1996;271:25198-203.
    • (1996) J Biol Chem , vol.271 , pp. 25198-25203
    • Salgia, R.1    Pisick, E.2    Sattler, M.3
  • 32
    • 34347230948 scopus 로고    scopus 로고
    • Platelet-derived growth factor receptor β-mediated phosphorylation of MUC1 enhances invasiveness in pancreatic adenocarcinoma cells
    • Singh PK, Wen Y, Swanson BJ, et al. Platelet-derived growth factor receptor β-mediated phosphorylation of MUC1 enhances invasiveness in pancreatic adenocarcinoma cells. Cancer Res 2007;67:5201-10.
    • (2007) Cancer Res , vol.67 , pp. 5201-5210
    • Singh, P.K.1    Wen, Y.2    Swanson, B.J.3
  • 33
    • 0029160043 scopus 로고
    • Association of the DF3/MUC1 breast cancer antigen with Grb2 and the Sos/Ras exchange protein
    • Pandey P, Kharbanda S, Kufe D. Association of the DF3/MUC1 breast cancer antigen with Grb2 and the Sos/Ras exchange protein. Cancer Res 1995;55:4000-3.
    • (1995) Cancer Res , vol.55 , pp. 4000-4003
    • Pandey, P.1    Kharbanda, S.2    Kufe, D.3
  • 35
    • 2442693937 scopus 로고    scopus 로고
    • The MUC1 oncoprotein activates the antiapoptotic phosphoinositide 3-kinase/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts
    • Raina D, Kharbanda S, Kufe D. The MUC1 oncoprotein activates the antiapoptotic phosphoinositide 3-kinase/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts. J Biol Chem 2004;279:20607-12.
    • (2004) J Biol Chem , vol.279 , pp. 20607-20612
    • Raina, D.1    Kharbanda, S.2    Kufe, D.3
  • 36
    • 0029870708 scopus 로고    scopus 로고
    • Endothelial-dependent mechanisms in chronic inflammatory leukocyte recruitment
    • Luscinskas FW, Gimbrone MA, Jr. Endothelial-dependent mechanisms in chronic inflammatory leukocyte recruitment. Annu Rev Med 1996;47:413-21.
    • (1996) Annu Rev Med , vol.47 , pp. 413-421
    • Luscinskas, F.W.1    Gimbrone Jr., M.A.2
  • 37
    • 0035845511 scopus 로고    scopus 로고
    • Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
    • Sorlie T, Perou CM, Tibshirani R, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A 2001;98:10869-74.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 10869-10874
    • Sorlie, T.1    Perou, C.M.2    Tibshirani, R.3
  • 38
    • 33746910265 scopus 로고    scopus 로고
    • Concordance among gene-expression-based predictors for breast cancer
    • Fan C, Oh DS, Wessels L, et al. Concordance among gene-expression-based predictors for breast cancer. N Engl J Med 2006;355:560-9.
    • (2006) N Engl J Med , vol.355 , pp. 560-569
    • Fan, C.1    Oh, D.S.2    Wessels, L.3
  • 39
    • 0032055962 scopus 로고    scopus 로고
    • Intercellular and intracellular events following the MHC-unrestricted TCR recognition of a tumor-specific peptide epitope on the epithelial antigen MUC1
    • Magarian-Blander J, Ciborowski P, Hsia S, Watkins SC, Finn OJ. Intercellular and intracellular events following the MHC-unrestricted TCR recognition of a tumor-specific peptide epitope on the epithelial antigen MUC1. J Immunol 1998;160:3111-20.
    • (1998) J Immunol , vol.160 , pp. 3111-3120
    • Magarian-Blander, J.1    Ciborowski, P.2    Hsia, S.3    Watkins, S.C.4    Finn, O.J.5
  • 40
    • 33746863317 scopus 로고    scopus 로고
    • Tyrosines in the MUC1 cytoplasmic tail modulate transcription via the extracellular signal-regulated kinase 1/2 and nuclear factor-κB pathways
    • Thompson EJ, Shanmugam K, Hattrup CL, et al. Tyrosines in the MUC1 cytoplasmic tail modulate transcription via the extracellular signal-regulated kinase 1/2 and nuclear factor-κB pathways. Mol Cancer Res 2006;4:489-97.
    • (2006) Mol Cancer Res , vol.4 , pp. 489-497
    • Thompson, E.J.1    Shanmugam, K.2    Hattrup, C.L.3
  • 41
    • 0032580202 scopus 로고    scopus 로고
    • Calcium oscillations increase the efficiency and specificity of gene expression
    • Dolmetsch RE, Xu K, Lewis RS. Calcium oscillations increase the efficiency and specificity of gene expression. Nature 1998;392:933-6.
    • (1998) Nature , vol.392 , pp. 933-936
    • Dolmetsch, R.E.1    Xu, K.2    Lewis, R.S.3
  • 42
    • 33744486857 scopus 로고    scopus 로고
    • Constitutive NF-κB and NFAT activation leads to stimulation of the BLyS survival pathway in aggressive B-cell lymphomas
    • Fu L, Lin-Lee YC, Pham LV, Tamayo A, Yoshimura L, Ford RJ. Constitutive NF-κB and NFAT activation leads to stimulation of the BLyS survival pathway in aggressive B-cell lymphomas. Blood 2006;107:4540-8.
    • (2006) Blood , vol.107 , pp. 4540-4548
    • Fu, L.1    Lin-Lee, Y.C.2    Pham, L.V.3    Tamayo, A.4    Yoshimura, L.5    Ford, R.J.6
  • 43
    • 0028151515 scopus 로고
    • Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527
    • Kaplan KB, Bibbins KB, Swedlow JR, Arnaud M, Morgan DO, Varmus HE. Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527. EMBO J 1994;13:4745-56.
    • (1994) EMBO J , vol.13 , pp. 4745-4756
    • Kaplan, K.B.1    Bibbins, K.B.2    Swedlow, J.R.3    Arnaud, M.4    Morgan, D.O.5    Varmus, H.E.6
  • 44
    • 0028986116 scopus 로고
    • pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk
    • Schaller MD, Parsons JT. pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk. Mol Cell Biol 1995;15:2635-45.
    • (1995) Mol Cell Biol , vol.15 , pp. 2635-2645
    • Schaller, M.D.1    Parsons, J.T.2
  • 45
    • 0036893185 scopus 로고    scopus 로고
    • DOCK2 associates with CrkL and regulates Rac1 in human leukemia cell lines
    • Nishihara H, Maeda M, Oda A, et al. DOCK2 associates with CrkL and regulates Rac1 in human leukemia cell lines. Blood 2002;100:3968-74.
    • (2002) Blood , vol.100 , pp. 3968-3974
    • Nishihara, H.1    Maeda, M.2    Oda, A.3
  • 46
    • 0030761596 scopus 로고    scopus 로고
    • Temperature dependency of calcium responses in mammary tumour cells
    • Oosawa Y, Imada C, Furuya K. Temperature dependency of calcium responses in mammary tumour cells. Cell Biochem Funct 1997;15:113-7.
    • (1997) Cell Biochem Funct , vol.15 , pp. 113-117
    • Oosawa, Y.1    Imada, C.2    Furuya, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.