-
1
-
-
0036883940
-
Pancreatic cancer biology and genetics
-
DOI 10.1038/nrc949
-
Bardeesy N, DePinho RA. Pancreatic cancer biology and genetics. Nat Rev Cancer 2002; 2: 897-909. (Pubitemid 37328891)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.12
, pp. 897-909
-
-
Bardeesy, N.1
DePinho, R.A.2
-
2
-
-
47949117602
-
Pancreatic cancer: From molecular pathogenesis to targeted therapy
-
Strimpakos A, Saif MW, Syrigos KN. Pancreatic cancer: from molecular pathogenesis to targeted therapy. Cancer Metastasis Rev 2008; 27: 495-522.
-
(2008)
Cancer Metastasis Rev
, vol.27
, pp. 495-522
-
-
Strimpakos, A.1
Saif, M.W.2
Syrigos, K.N.3
-
3
-
-
18644378003
-
Expression and localization of human multidrug resistance protein (ABCC) family members in pancreatic carcinoma
-
DOI 10.1002/ijc.20831
-
Konig J, Hartel M, Nies AT, Martignoni ME, Guo J, Bü chler MW et al. Expression and localization of human multidrug resistance protein (ABCC) family members in pancreatic carcinoma. Int J Cancer 2005; 115: 359-367. (Pubitemid 40663738)
-
(2005)
International Journal of Cancer
, vol.115
, Issue.3
, pp. 359-367
-
-
Konig, J.1
Hartel, M.2
Nies, A.T.3
Martignoni, M.E.4
Guo, J.5
Buchler, M.W.6
Friess, H.7
Keppler, D.8
-
4
-
-
0031027559
-
Recurrence after resection for ductal adenocarcinoma of the pancreas
-
DOI 10.1007/s002689900215
-
Sperti C, Pasquali C, Piccoli A, Pedrazzoli S. Recurrence after resection for ductal adenocarcinoma of the pancreas. World J Surg 1997; 21: 195-200. (Pubitemid 27053441)
-
(1997)
World Journal of Surgery
, vol.21
, Issue.2
, pp. 195-200
-
-
Sperti, C.1
Pasquali, C.2
Piccoli, A.3
Pedrazzoli, S.4
-
5
-
-
78651108985
-
Pancreatic cancer: Understanding and overcoming chemoresistance
-
Wang Z, Li Y, Ahmad A, Banerjee S, Azmi AS, Kong D et al. Pancreatic cancer: understanding and overcoming chemoresistance. Nat Rev Gastroenterol Hepatol 2011; 8: 27-33.
-
(2011)
Nat Rev Gastroenterol Hepatol
, vol.8
, pp. 27-33
-
-
Wang, Z.1
Li, Y.2
Ahmad, A.3
Banerjee, S.4
Azmi, A.S.5
Kong, D.6
-
6
-
-
65349136896
-
Classical resistance mechanisms
-
Jager w. Classical resistance mechanisms. Int J Clin Pharmacol Ther 2009; 47: 46-48.
-
(2009)
Int J Clin Pharmacol Ther
, vol.47
, pp. 46-48
-
-
Jager, W.1
-
7
-
-
0036364467
-
Multidrug resistance in cancer: Role of ATP-dependent transporters
-
Gottesman MM, Fojo T, Bates SE. Multidrug resistance in cancer: role of ATPdependent transporters. Nat Rev Cancer 2002; 2: 48-58. (Pubitemid 37328807)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.1
, pp. 48-58
-
-
Gottesman, M.M.1
Fojo, T.2
Bates, S.E.3
-
8
-
-
20144385541
-
Regulation of MDR1 expression and drug resistance by a positive feedback loop involving hyaluronan, phosphoinositide 3-kinase, and ErbB2
-
DOI 10.1074/jbc.M500737200
-
Misra S, Ghatak S, Toole BP. Regulation of MDR1 expression and drug resistance by a positive feedback loop involving hyaluronan, phosphoinositide 3-kinase, and ErbB2. J Biol Chem 2005; 280: 20310-20315. (Pubitemid 40776728)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.21
, pp. 20310-20315
-
-
Misra, S.1
Ghatak, S.2
Toole, B.P.3
-
9
-
-
40949121607
-
ABC multidrug transporters: Structure, function and role in chemoresistance
-
DOI 10.2217/14622416.9.1.105
-
Sharom FJ. ABC multidrug transporters: structure, function and role in chemoresistance. Pharmacogenomics 2008; 9: 105-127. (Pubitemid 351560534)
-
(2008)
Pharmacogenomics
, vol.9
, Issue.1
, pp. 105-127
-
-
Sharom, F.J.1
-
10
-
-
8544230666
-
Phosphatidylinositol 3′-kinase activation leads to multidrug resistance protein-1 expression and subsequent chemoresistance in advanced prostate cancer cells
-
DOI 10.1158/0008-5472.CAN-04-1612
-
Lee Jr JT, Steelman LS, McCubrey JA. Phosphatidylinositol 3'-kinase activation leads to multidrug resistance protein-1 expression and subsequent chemoresistance in advanced prostate cancer cells. Cancer Res 2004; 64: 8397-8404. (Pubitemid 39491779)
-
(2004)
Cancer Research
, vol.64
, Issue.22
, pp. 8397-8404
-
-
Lee Jr., J.T.1
Steelman, L.S.2
McCubrey, J.A.3
-
11
-
-
2442693937
-
L pathways in rat 3Y1 fibroblasts
-
DOI 10.1074/jbc.M310538200
-
Raina D, Kharbanda S, Kufe D. The MUC1 oncoprotein activates the anti-apoptotic phosphoinositide 3-kinase/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts. J Biol Chem 2004; 279: 20607-20612. (Pubitemid 38656454)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.20
, pp. 20607-20612
-
-
Raina, D.1
Kharbanda, S.2
Kufe, D.3
-
12
-
-
34347217519
-
MUC1 oncoprotein promotes refractoriness to chemotherapy in thyroid cancer cells
-
DOI 10.1158/0008-5472.CAN-06-4197
-
Siragusa M, Zerilli M, Iovino F, Francipane MG, Lombardo Y, Ricci-Vitiani L et al. MUC1 oncoprotein promotes refractoriness to chemotherapy in thyroid cancer cells. Cancer Res 2007; 67: 5522-5530. (Pubitemid 46997294)
-
(2007)
Cancer Research
, vol.67
, Issue.11
, pp. 5522-5530
-
-
Siragusa, M.1
Zerilli, M.2
Iovino, F.3
Francipane, M.G.4
Lombardo, Y.5
Ricci-Vitiani, L.6
Di Gesu, G.7
Todaro, M.8
De Maria, R.9
Stassi, G.10
-
13
-
-
0347123435
-
Mucins in cancer: Protection and control of the cell surface
-
Hollingsworth MA, Swanson BJ. Mucins in cancer: protection and control of the cell surface. Nat Rev Cancer 2004; 4: 45-60. (Pubitemid 38082153)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.1
, pp. 45-60
-
-
Hollingsworth, M.A.1
Swanson, B.J.2
-
14
-
-
2442568891
-
MUC1 and MUC2 in pancreatic neoplasia
-
DOI 10.1136/jcp.2003.013292
-
Levi E, Klimstra DS, Andea A, Basturk O, Adsay NV. MUC1 and MUC2 in pancreatic neoplasia. J Clin Pathol 2004; 57: 456-462. (Pubitemid 38621788)
-
(2004)
Journal of Clinical Pathology
, vol.57
, Issue.5
, pp. 456-462
-
-
Levi, E.1
Klimstra, D.S.2
Adsay, N.V.3
Andea, A.4
Basturk, O.5
-
15
-
-
0346251199
-
MUC1 and MUC2 expression in pancreatic ductal carcinoma obtained by fine-needle aspiration
-
DOI 10.1002/cncr.11857
-
Chhieng DC, Benson E, Eltoum I, Eloubeidi MA, Jhala N, Jhala D et al. MUC1 and MUC2 expression in pancreatic ductal carcinoma obtained by fine-needle aspiration. Cancer 2003; 99: 365-371. (Pubitemid 38017536)
-
(2003)
Cancer
, vol.99
, Issue.6
, pp. 365-371
-
-
Chhieng, D.C.1
Benson, E.2
Eltoum, I.3
Eloubeidi, M.A.4
Jhala, N.5
Jhala, D.6
Siegal, G.P.7
Grizzle, W.E.8
Manne, U.9
-
17
-
-
70450247207
-
Mucins in cancer: Function, prognosis and therapy
-
Kufe DW. Mucins in cancer: function, prognosis and therapy. Nat Rev Cancer 2009; 9: 874-885.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 874-885
-
-
Kufe, D.W.1
-
18
-
-
48849100795
-
The cytoplasmic tail of MUC1: A very busy place
-
Carson DD. The cytoplasmic tail of MUC1: a very busy place. Sci Signal 2008; 1: pe35.
-
(2008)
Sci Signal
, vol.1
-
-
Carson, D.D.1
-
19
-
-
79959891751
-
Pancreatic ductal adenocarcinoma mice lacking mucin 1 have a profound defect in tumor growth and metastasis
-
Besmer DM, Curry JM, Roy LD, Tinder TL, Sahraei M, Schettini J et al. Pancreatic ductal adenocarcinoma mice lacking mucin 1 have a profound defect in tumor growth and metastasis. Cancer Res 2011; 71: 4432-4442.
-
(2011)
Cancer Res
, vol.71
, pp. 4432-4442
-
-
Besmer, D.M.1
Curry, J.M.2
Roy, L.D.3
Tinder, T.L.4
Sahraei, M.5
Schettini, J.6
-
20
-
-
79953061206
-
MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition
-
Roy LD, Sahraei M, Subramani DB, Besmer D, Nath S, Tinder TL et al. MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition. Oncogene 2011; 30: 1449-1459.
-
(2011)
Oncogene
, vol.30
, pp. 1449-1459
-
-
Roy, L.D.1
Sahraei, M.2
Subramani, D.B.3
Besmer, D.4
Nath, S.5
Tinder, T.L.6
-
21
-
-
84870059553
-
MUC1 regulates PDGFA expression during pancreatic cancer progression
-
Sahraei M, Roy LD, Curry JM, Teresa TL, Nath S, Besmer D et al. MUC1 regulates PDGFA expression during pancreatic cancer progression. Oncogene 2012; 31: 4935-4945.
-
(2012)
Oncogene
, vol.31
, pp. 4935-4945
-
-
Sahraei, M.1
Roy, L.D.2
Curry, J.M.3
Teresa, T.L.4
Nath, S.5
Besmer, D.6
-
22
-
-
77958494724
-
The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF
-
Behrens ME, Grandgenett PM, Bailey JM, Singh PK, Yi CH, Yu F et al. The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF. Oncogene 2010; 29: 5667-5677.
-
(2010)
Oncogene
, vol.29
, pp. 5667-5677
-
-
Behrens, M.E.1
Grandgenett, P.M.2
Bailey, J.M.3
Singh, P.K.4
Yi, C.H.5
Yu, F.6
-
23
-
-
10744220453
-
Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents
-
DOI 10.1016/S1535-6108(04)00020-0, PII S1535610804000200
-
Ren J, Agata N, Chen D, Li Y, Yu WH, Huang L et al. Human MUC1 carcinomaassociated protein confers resistance to genotoxic anticancer agents. Cancer Cell 2004; 5: 163-175. (Pubitemid 38283802)
-
(2004)
Cancer Cell
, vol.5
, Issue.2
, pp. 163-175
-
-
Ren, J.1
Agata, N.2
Chen, D.3
Li, Y.4
Yu, W.-H.5
Huang, L.6
Raina, D.7
Chen, W.8
Kharbanda, S.9
Kufe, D.10
-
24
-
-
0345688182
-
Transcriptional regulation of ABC drug transporters
-
DOI 10.1038/sj.onc.1206950, Drug Resistance
-
Scotto KW. Transcriptional regulation of ABC drug transporters. Oncogene 2003; 22: 7496-7511. (Pubitemid 37487172)
-
(2003)
Oncogene
, vol.22
, Issue.47
, pp. 7496-7511
-
-
Scotto, K.W.1
-
25
-
-
0034806474
-
Identification of DNA-protein interactions in the 5′ flanking and 5′ untranslated regions of the human multidrug resistance protein (MRP1) gene: Evaluation of a putative antioxidant response element/AP-1 binding site
-
DOI 10.1006/bbrc.2001.5262
-
Kurz EU, Cole SP, Deeley RG. Identification of DNA-protein interactions in the 5' flanking and 5' untranslated regions of the human multidrug resistance protein (MRP1) gene: evaluation of a putative antioxidant response element/AP-1 binding site. Biochem Biophys Res Commun 2001; 285: 981-990. (Pubitemid 32918034)
-
(2001)
Biochemical and Biophysical Research Communications
, vol.285
, Issue.4
, pp. 981-990
-
-
Kurz, E.U.1
Cole, S.P.C.2
Deeley, R.G.3
-
26
-
-
33746863317
-
Tyrosines in the MUC1 cytoplasmic tail modulate transcription via the extracellular signal-regulated kinase 1/2 and nuclear factor-κB pathways
-
DOI 10.1158/1541-7786.MCR-06-0038
-
Thompson EJ, Shanmugam K, Hattrup CL, Kotlarczyk KL, Gutierrez A, Bradley JM et al. Tyrosines in the MUC1 cytoplasmic tail modulate transcription via the extracellular signal-regulated kinase 1/2 and nuclear factor-kappaB pathways. Mol Can Res 2006; 4: 489-497. (Pubitemid 44197044)
-
(2006)
Molecular Cancer Research
, vol.4
, Issue.7
, pp. 489-497
-
-
Thompson, E.J.1
Shanmugam, K.2
Hattrup, C.L.3
Kotlarczyk, K.L.4
Gutierrez, A.5
Bradley, J.M.6
Mukherjee, P.7
Gendler, S.J.8
-
27
-
-
77958494724
-
The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF
-
Behrens ME, Grandgenett PM, Bailey JM, Singh PK, Yi CH, Yu F et al. The reactive tumor microenvironment: MUC1 signaling directly reprograms transcription of CTGF. Oncogene 2010; 29: 5667-5677.
-
(2010)
Oncogene
, vol.29
, pp. 5667-5677
-
-
Behrens, M.E.1
Grandgenett, P.M.2
Bailey, J.M.3
Singh, P.K.4
Yi, C.H.5
Yu, F.6
-
28
-
-
84870059553
-
MUC1 regulates PDGFA expression during pancreatic cancer progression
-
Sahraei M, Roy LD, Curry JM, Teresa TL, Nath S, Besmer D et al. MUC1 regulates PDGFA expression during pancreatic cancer progression. Oncogene 2012; 31: 4935-4945.
-
(2012)
Oncogene
, vol.31
, pp. 4935-4945
-
-
Sahraei, M.1
Roy, L.D.2
Curry, J.M.3
Teresa, T.L.4
Nath, S.5
Besmer, D.6
-
29
-
-
9144266295
-
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
-
DOI 10.1016/S1535-6108(03)00309-X
-
Hingorani SR, Petricoin EF, Maitra A, Rajapakse V, King C, Jacobetz MA et al. Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell 2003; 4: 437-450. (Pubitemid 38050041)
-
(2003)
Cancer Cell
, vol.4
, Issue.6
, pp. 437-450
-
-
Hingorani, S.R.1
Petricoin III, E.F.2
Maitra, A.3
Rajapakse, V.4
King, C.5
Jacobetz, M.A.6
Ross, S.7
Conrads, T.P.8
Veenstra, T.D.9
Hitt, B.A.10
Kawaguchi, Y.11
Johann, D.12
Liotta, L.A.13
Crawford, H.C.14
Putt, M.E.15
Jacks, T.16
Wright, C.V.E.17
Hruban, R.H.18
Lowy, A.M.19
Tuveson, D.A.20
more..
-
30
-
-
51549099068
-
MUC1 enhances tumor progression and contributes toward immunosuppression in a mouse model of spontaneous pancreatic adenocarcinoma
-
Tinder TL, Subramani DB, Basu GD, Bradley JM, Schettini J, Million A et al. MUC1 enhances tumor progression and contributes toward immunosuppression in a mouse model of spontaneous pancreatic adenocarcinoma. J Immunol 2008; 181: 3116-3125.
-
(2008)
J Immunol
, vol.181
, pp. 3116-3125
-
-
Tinder, T.L.1
Subramani, D.B.2
Basu, G.D.3
Bradley, J.M.4
Schettini, J.5
Million, A.6
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