-
1
-
-
77649276038
-
The extracellular matrix as a modulator of the inflammatory and reparative response following myocardial infarction
-
Dobaczewski M, Gonzalez-Quesada C, Frangogiannis NG. The extracellular matrix as a modulator of the inflammatory and reparative response following myocardial infarction. J Mol Cell Cardiol. 2010;48:504-511.
-
(2010)
J Mol Cell Cardiol.
, vol.48
, pp. 504-511
-
-
Dobaczewski, M.1
Gonzalez-Quesada, C.2
Frangogiannis, N.G.3
-
2
-
-
53249095498
-
The immune system and cardiac repair
-
Frangogiannis NG. The immune system and cardiac repair. Pharmacol Res. 2008;58:88-111.
-
(2008)
Pharmacol Res.
, vol.58
, pp. 88-111
-
-
Frangogiannis, N.G.1
-
3
-
-
3042702881
-
Inflammatory cytokines and postmyocardial infarction remodeling
-
Nian M, Lee P, Khaper N, Liu P. Inflammatory cytokines and postmyocardial infarction remodeling. Circ Res. 2004;94:1543-1553.
-
(2004)
Circ Res.
, vol.94
, pp. 1543-1553
-
-
Nian, M.1
Lee, P.2
Khaper, N.3
Liu, P.4
-
4
-
-
70349750287
-
Survival and cardiac remodeling after myocardial infarction are critically dependent on the host innate immune interleukin-1 receptor-associated kinase-4 signaling: A regulator of bone marrow-derived dendritic cells
-
Maekawa Y, Mizue N, Chan A, Shi Y, Liu Y, Dawood S, Chen M, Dawood F, De Couto G, Li GH, Suzuki N, Yeh WC, Gramolini A, Medin JA, Liu PP. Survival and cardiac remodeling after myocardial infarction are critically dependent on the host innate immune interleukin-1 receptor-associated kinase-4 signaling: A regulator of bone marrow-derived dendritic cells. Circulation. 2009;120:1401-1414.
-
(2009)
Circulation.
, vol.120
, pp. 1401-1414
-
-
Maekawa, Y.1
Mizue, N.2
Chan, A.3
Shi, Y.4
Liu, Y.5
Dawood, S.6
Chen, M.7
Dawood, F.8
De Couto, G.9
Li, G.H.10
Suzuki, N.11
Yeh, W.C.12
Gramolini, A.13
Medin, J.A.14
Liu, P.P.15
-
5
-
-
35748974863
-
Myocardial matrix remodeling and the matrix metalloproteinases: Influence on cardiac form and function
-
Spinale FG. Myocardial matrix remodeling and the matrix metalloproteinases: Influence on cardiac form and function. Physiol Rev. 2007;87:1285-1342.
-
(2007)
Physiol Rev.
, vol.87
, pp. 1285-1342
-
-
Spinale, F.G.1
-
6
-
-
79952745548
-
Lack of fibronectin-EDA promotes survival and prevents adverse remodeling and heart function deterioration after myocardial infarction
-
Arslan F, Smeets MB, Riem Vis PW, Karper JC, Quax PH, Bongartz LG, Peters JH, Hoefer IE, Doevendans PA, Pasterkamp G, De Kleijn DP. Lack of fibronectin-EDA promotes survival and prevents adverse remodeling and heart function deterioration after myocardial infarction. Circ Res. 2011;108:582-592.
-
(2011)
Circ Res.
, vol.108
, pp. 582-592
-
-
Arslan, F.1
Smeets, M.B.2
Riem Vis, P.W.3
Karper, J.C.4
Quax, P.H.5
Bongartz, L.G.6
Peters, J.H.7
Hoefer, I.E.8
Doevendans, P.A.9
Pasterkamp, G.10
De Kleijn, D.P.11
-
7
-
-
73549107232
-
Integrin-mediated transforming growth factor-beta activation, a potential therapeutic target in fibrogenic disorders
-
Nishimura SL. Integrin-mediated transforming growth factor-beta activation, a potential therapeutic target in fibrogenic disorders. Am J Pathol. 2009;175:1362-1370.
-
(2009)
Am J Pathol.
, vol.175
, pp. 1362-1370
-
-
Nishimura, S.L.1
-
8
-
-
76849087987
-
Myocardial remodeling after infarction: The role of myofibroblasts
-
Van Den Borne SW, Diez J, Blankesteijn WM, Verjans J, Hofstra L, Narula J. Myocardial remodeling after infarction: The role of myofibroblasts. Nat Rev Cardiol. 2010;7:30-37.
-
(2010)
Nat Rev Cardiol.
, vol.7
, pp. 30-37
-
-
Van Den Borne, S.W.1
Diez, J.2
Blankesteijn, W.M.3
Verjans, J.4
Hofstra, L.5
Narula, J.6
-
9
-
-
84863337877
-
Regulatory role of dendritic cells in postinfarction healing and left ventricular remodeling
-
Anzai A, Anzai T, Nagai S, et al. Regulatory role of dendritic cells in postinfarction healing and left ventricular remodeling. Circulation. 2012;125:1234-1245.
-
(2012)
Circulation.
, vol.125
, pp. 1234-1245
-
-
Anzai, A.1
Anzai, T.2
Nagai, S.3
-
10
-
-
84860255582
-
MT1-MMP-dependent remodeling of cardiac extracellular matrix structure and function following myocardial infarction
-
Koenig GC, Rowe RG, Day SM, Sabeh F, Atkinson JJ, Cooke KR, Weiss SJ. MT1-MMP-dependent remodeling of cardiac extracellular matrix structure and function following myocardial infarction. Am J Pathol. 2012;180:1863-1878.
-
(2012)
Am J Pathol.
, vol.180
, pp. 1863-1878
-
-
Koenig, G.C.1
Rowe, R.G.2
Day, S.M.3
Sabeh, F.4
Atkinson, J.J.5
Cooke, K.R.6
Weiss, S.J.7
-
11
-
-
20444489650
-
Critical role of endogenous thrombospondin-1 in preventing expansion of healing myocardial infarcts
-
Frangogiannis NG, Ren G, Dewald O, Zymek P, Haudek S, Koerting A, Winkelmann K, Michael LH, Lawler J, Entman ML. Critical role of endogenous thrombospondin-1 in preventing expansion of healing myocardial infarcts. Circulation. 2005;111:2935-2942.
-
(2005)
Circulation.
, vol.111
, pp. 2935-2942
-
-
Frangogiannis, N.G.1
Ren, G.2
Dewald, O.3
Zymek, P.4
Haudek, S.5
Koerting, A.6
Winkelmann, K.7
Michael, L.H.8
Lawler, J.9
Entman, M.L.10
-
12
-
-
0035947750
-
Exaggerated left ventricular dilation and reduced collagen deposition after myocardial infarction in mice lacking osteopontin
-
Trueblood NA, Xie Z, Communal C, Sam F, Ngoy S, Liaw L, Jenkins AW, Wang J, Sawyer DB, Bing OH, Apstein CS, Colucci WS, Singh K. Exaggerated left ventricular dilation and reduced collagen deposition after myocardial infarction in mice lacking osteopontin. Circ Res. 2001;88:1080-1087.
-
(2001)
Circ Res.
, vol.88
, pp. 1080-1087
-
-
Trueblood, N.A.1
Xie, Z.2
Communal, C.3
Sam, F.4
Ngoy, S.5
Liaw, L.6
Jenkins, A.W.7
Wang, J.8
Sawyer, D.B.9
Bing, O.H.10
Apstein, C.S.11
Colucci, W.S.12
Singh, K.13
-
13
-
-
77749242706
-
Tenascin-C may aggravate left ventricular remodeling and function after myocardial infarction in mice
-
Nishioka T, Onishi K, Shimojo N, Nagano Y, Matsusaka H, Ikeuchi M, Ide T, Tsutsui H, Hiroe M, Yoshida T, Imanaka-Yoshida K. Tenascin-C may aggravate left ventricular remodeling and function after myocardial infarction in mice. Am J Physiol Heart Circ Physiol. 2010;298:H1072-H1078.
-
(2010)
Am J Physiol Heart Circ Physiol.
, vol.298
, pp. 1072-1078
-
-
Nishioka, T.1
Onishi, K.2
Shimojo, N.3
Nagano, Y.4
Matsusaka, H.5
Ikeuchi, M.6
Ide, T.7
Tsutsui, H.8
Hiroe, M.9
Yoshida, T.10
Imanaka-Yoshida, K.11
-
14
-
-
79961087846
-
Sparc mediates early extracellular matrix remodeling following myocardial infarction
-
McCurdy SM, Dai Q, Zhang J, Zamilpa R, Ramirez TA, Dayah T, Nguyen N, Jin YF, Bradshaw AD, Lindsey ML. SPARC mediates early extracellular matrix remodeling following myocardial infarction. Am J Physiol Heart Circ Physiol. 2011;301:H497-H505.
-
(2011)
Am J Physiol Heart Circ Physiol.
, vol.301
, pp. 497-505
-
-
McCurdy, S.M.1
Dai, Q.2
Zhang, J.3
Zamilpa, R.4
Ramirez, T.A.5
Dayah, T.6
Nguyen, N.7
Jin, Y.F.8
Bradshaw, A.D.9
Lindsey, M.L.10
-
15
-
-
34547691243
-
Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair
-
Khn B, del Monte F, Hajjar RJ, Chang YS, Lebeche D, Arab S, Keating MT. Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair. Nat Med. 2007;13:962-969.
-
(2007)
Nat Med.
, vol.13
, pp. 962-969
-
-
Khn, B.1
Del Monte, F.2
Hajjar, R.J.3
Chang, Y.S.4
Lebeche, D.5
Arab, S.6
Keating, M.T.7
-
16
-
-
39549107343
-
Periostin is essential for cardiac healing after acute myocardial infarction
-
Shimazaki M, Nakamura K, Kii I, Kashima T, Amizuka N, Li M, Saito M, Fukuda K, Nishiyama T, Kitajima S, Saga Y, Fukayama M, Sata M, Kudo A. Periostin is essential for cardiac healing after acute myocardial infarction. J Exp Med. 2008;205:295-303.
-
(2008)
J Exp Med.
, vol.205
, pp. 295-303
-
-
Shimazaki, M.1
Nakamura, K.2
Kii, I.3
Kashima, T.4
Amizuka, N.5
Li, M.6
Saito, M.7
Fukuda, K.8
Nishiyama, T.9
Kitajima, S.10
Saga, Y.11
Fukayama, M.12
Sata, M.13
Kudo, A.14
-
17
-
-
84871416039
-
Myocardial connective tissue growth factor (CCN2/CTGF) attenuates left ventricular remodeling after myocardial infarction
-
Gravning J, rn S, Kaasbll OJ, Martinov VN, Manhenke C, Dickstein K, Edvardsen T, Attramadal H, Ahmed MS. Myocardial connective tissue growth factor (CCN2/CTGF) attenuates left ventricular remodeling after myocardial infarction. PLoS One. 2012;7:e52120.
-
(2012)
PLoS One.
, vol.7
-
-
Gravning, J.1
Rn, S.2
Kaasbll, O.J.3
Martinov, V.N.4
Manhenke, C.5
Dickstein, K.6
Edvardsen, T.7
Attramadal, H.8
Ahmed, M.S.9
-
18
-
-
33846570959
-
Increased expression of syndecan-1 protects against cardiac dilatation and dysfunction after myocardial infarction
-
Vanhoutte D, Schellings MW, Gtte M, Swinnen M, Herias V, Wild MK, Vestweber D, Chorianopoulos E, Corts V, Rigotti A, Stepp MA, Van De Werf F, Carmeliet P, Pinto YM, Heymans S. Increased expression of syndecan-1 protects against cardiac dilatation and dysfunction after myocardial infarction. Circulation. 2007;115:475-482.
-
(2007)
Circulation.
, vol.115
, pp. 475-482
-
-
Vanhoutte, D.1
Schellings, M.W.2
Gtte, M.3
Swinnen, M.4
Herias, V.5
Wild, M.K.6
Vestweber, D.7
Chorianopoulos, E.8
Corts, V.9
Rigotti, A.10
Stepp, M.A.11
Van De Werf, F.12
Carmeliet, P.13
Pinto, Y.M.14
Heymans, S.15
-
19
-
-
0035020956
-
Plasma levels of syndecan-4 (ryudocan) are elevated in patients with acute myocardial infarction
-
Kojima T, Takagi A, Maeda M, Segawa T, Shimizu A, Yamamoto K, Matsushita T, Saito H. Plasma levels of syndecan-4 (ryudocan) are elevated in patients with acute myocardial infarction. Thromb Haemost. 2001;85:793-799.
-
(2001)
Thromb Haemost.
, vol.85
, pp. 793-799
-
-
Kojima, T.1
Takagi, A.2
Maeda, M.3
Segawa, T.4
Shimizu, A.5
Yamamoto, K.6
Matsushita, T.7
Saito, H.8
-
20
-
-
79958150282
-
Syndecan-4 prevents cardiac rupture and dysfunction after myocardial infarction
-
Matsui Y, Ikesue M, Danzaki K, Morimoto J, Sato M, Tanaka S, Kojima T, Tsutsui H, Uede T. Syndecan-4 prevents cardiac rupture and dysfunction after myocardial infarction. Circ Res. 2011;108:1328-1339.
-
(2011)
Circ Res.
, vol.108
, pp. 1328-1339
-
-
Matsui, Y.1
Ikesue, M.2
Danzaki, K.3
Morimoto, J.4
Sato, M.5
Tanaka, S.6
Kojima, T.7
Tsutsui, H.8
Uede, T.9
-
21
-
-
40549086587
-
Biglycan is required for adaptive remodeling after myocardial infarction
-
Westermann D, Mersmann J, Melchior A, et al. Biglycan is required for adaptive remodeling after myocardial infarction. Circulation. 2008;117:1269-1276.
-
(2008)
Circulation.
, vol.117
, pp. 1269-1276
-
-
Westermann, D.1
Mersmann, J.2
Melchior, A.3
-
22
-
-
77649275856
-
Contribution of extracellular matrix to the mechanical properties of the heart
-
Fomovsky GM, Thomopoulos S, Holmes JW. Contribution of extracellular matrix to the mechanical properties of the heart. J Mol Cell Cardiol. 2010;48:490-496.
-
(2010)
J Mol Cell Cardiol.
, vol.48
, pp. 490-496
-
-
Fomovsky, G.M.1
Thomopoulos, S.2
Holmes, J.W.3
-
23
-
-
0031657267
-
Regulation of extracellular matrix proteins in pressure-overload cardiac hypertrophy: Effects of angiotensin converting enzyme inhibition
-
Grimm D, Kromer EP, Bcker W, Bruckschlegel G, Holmer SR, Riegger GA, Schunkert H. Regulation of extracellular matrix proteins in pressure-overload cardiac hypertrophy: Effects of angiotensin converting enzyme inhibition. J Hypertens. 1998;16:1345-1355.
-
(1998)
J Hypertens.
, vol.16
, pp. 1345-1355
-
-
Grimm, D.1
Kromer, E.P.2
Bcker, W.3
Bruckschlegel, G.4
Holmer, S.R.5
Riegger, G.A.6
Schunkert, H.7
-
24
-
-
0034970828
-
Extracellular matrix proteins in cardiac fibroblasts derived from rat hearts with chronic pressure overload: Effects of beta-receptor blockade
-
Grimm D, Huber M, Jabusch HC, Shakibaei M, Fredersdorf S, Paul M, Riegger GA, Kromer EP. Extracellular matrix proteins in cardiac fibroblasts derived from rat hearts with chronic pressure overload: Effects of beta-receptor blockade. J Mol Cell Cardiol. 2001;33:487-501.
-
(2001)
J Mol Cell Cardiol.
, vol.33
, pp. 487-501
-
-
Grimm, D.1
Huber, M.2
Jabusch, H.C.3
Shakibaei, M.4
Fredersdorf, S.5
Paul, M.6
Riegger, G.A.7
Kromer, E.P.8
-
25
-
-
84875806579
-
Differential regulation of extracellular matrix constituents in myocardial remodeling with and without heart failure following pressure overload
-
Skrbic B, Bjrnstad JL, Marstein HS, Carlson CR, Sjaastad I, Nygrd S, Bjrnstad S, Christensen G, Tnnessen T. Differential regulation of extracellular matrix constituents in myocardial remodeling with and without heart failure following pressure overload. Matrix Biol. 2013;32:133-142.
-
(2013)
Matrix Biol.
, vol.32
, pp. 133-142
-
-
Skrbic, B.1
Bjrnstad, J.L.2
Marstein, H.S.3
Carlson, C.R.4
Sjaastad, I.5
Nygrd, S.6
Bjrnstad, S.7
Christensen, G.8
Tnnessen, T.9
-
26
-
-
0025826964
-
Impaired diastolic function and coronary reserve in genetic hypertension. Role of interstitial fibrosis and medial thickening of intramyocardial coronary arteries
-
Brilla CG, Janicki JS, Weber KT. Impaired diastolic function and coronary reserve in genetic hypertension. Role of interstitial fibrosis and medial thickening of intramyocardial coronary arteries. Circ Res. 1991;69:107-115.
-
(1991)
Circ Res.
, vol.69
, pp. 107-115
-
-
Brilla, C.G.1
Janicki, J.S.2
Weber, K.T.3
-
27
-
-
18244385727
-
Distinct upregulation of extracellular matrix genes in transition from hypertrophy to hypertensive heart failure
-
Rys J, Leskinen H, Ilves M, Ruskoaho H. Distinct upregulation of extracellular matrix genes in transition from hypertrophy to hypertensive heart failure. Hypertension. 2005;45:927-933.
-
(2005)
Hypertension.
, vol.45
, pp. 927-933
-
-
Rys, J.1
Leskinen, H.2
Ilves, M.3
Ruskoaho, H.4
-
28
-
-
77955803946
-
Metoprolol treatment lowers thrombospondin-4 expression in rats with myocardial infarction and left ventricular hypertrophy
-
Mustonen E, Leskinen H, Aro J, Luodonp M, Vuolteenaho O, Ruskoaho H, Rys J. Metoprolol treatment lowers thrombospondin-4 expression in rats with myocardial infarction and left ventricular hypertrophy. Basic Clin Pharmacol Toxicol. 2010;107:709-717.
-
(2010)
Basic Clin Pharmacol Toxicol.
, vol.107
, pp. 709-717
-
-
Mustonen, E.1
Leskinen, H.2
Aro, J.3
Luodonp, M.4
Vuolteenaho, O.5
Ruskoaho, H.6
Rys, J.7
-
29
-
-
9644266547
-
Osteopontin modulates myocardial hypertrophy in response to chronic pressure overload in mice
-
Xie Z, Singh M, Singh K. Osteopontin modulates myocardial hypertrophy in response to chronic pressure overload in mice. Hypertension. 2004;44:826-831.
-
(2004)
Hypertension.
, vol.44
, pp. 826-831
-
-
Xie, Z.1
Singh, M.2
Singh, K.3
-
30
-
-
77649271479
-
Extracellular matrix remodeling during the progression of volume overload-induced heart failure
-
Hutchinson KR, Stewart JA Jr, Lucchesi PA. Extracellular matrix remodeling during the progression of volume overload-induced heart failure. J Mol Cell Cardiol. 2010;48:564-569.
-
(2010)
J Mol Cell Cardiol.
, vol.48
, pp. 564-569
-
-
Hutchinson, K.R.1
Stewart Jr., J.A.2
Lucchesi, P.A.3
-
31
-
-
65449142922
-
Microarray identifies extensive downregulation of noncollagen extracellular matrix and profibrotic growth factor genes in chronic isolated mitral regurgitation in the dog
-
Zheng J, Chen Y, Pat B, Dellitalia LA, Tillson M, Dillon AR, Powell PC, Shi K, Shah N, Denney T, Husain A, DellItalia LJ. Microarray identifies extensive downregulation of noncollagen extracellular matrix and profibrotic growth factor genes in chronic isolated mitral regurgitation in the dog. Circulation. 2009;119:2086-2095.
-
(2009)
Circulation.
, vol.119
, pp. 2086-2095
-
-
Zheng, J.1
Chen, Y.2
Pat, B.3
Dellitalia, L.A.4
Tillson, M.5
Dillon, A.R.6
Powell, P.C.7
Shi, K.8
Shah, N.9
Denney, T.10
Husain, A.11
Dellitalia, L.J.12
-
32
-
-
17844405587
-
A comparative serial echocardiographic analysis of cardiac structure and function in rats subjected to pressure or volume overload
-
Cantor EJ, Babick AP, Vasanji Z, Dhalla NS, Netticadan T. A comparative serial echocardiographic analysis of cardiac structure and function in rats subjected to pressure or volume overload. J Mol Cell Cardiol. 2005;38:777-786.
-
(2005)
J Mol Cell Cardiol.
, vol.38
, pp. 777-786
-
-
Cantor, E.J.1
Babick, A.P.2
Vasanji, Z.3
Dhalla, N.S.4
Netticadan, T.5
-
33
-
-
0026100997
-
Specific alterations in the distribution of extracellular matrix components within rat myocardium during the development of pressure overload
-
Contard F, Koteliansky V, Marotte F, Dubus I, Rappaport L, Samuel JL. Specific alterations in the distribution of extracellular matrix components within rat myocardium during the development of pressure overload. Lab Invest. 1991;64:65-75.
-
(1991)
Lab Invest.
, vol.64
, pp. 65-75
-
-
Contard, F.1
Koteliansky, V.2
Marotte, F.3
Dubus, I.4
Rappaport, L.5
Samuel, J.L.6
-
34
-
-
84876293435
-
Noninvasive imaging of myocardial extracellular matrix for assessment of fibrosis
-
Won S, Davies-Venn C, Liu S, Bluemke DA. Noninvasive imaging of myocardial extracellular matrix for assessment of fibrosis. Current Opin Cardiol. 2013;28:282-289.
-
(2013)
Current Opin Cardiol.
, vol.28
, pp. 282-289
-
-
Won, S.1
Davies-Venn, C.2
Liu, S.3
Bluemke, D.A.4
-
35
-
-
77649275832
-
Non-fibrillar collagens key mediators of post-infarction cardiac remodeling
-
Shamhart PE, Meszaros JG. Non-fibrillar collagens: Key mediators of post-infarction cardiac remodeling J Mol Cell Cardiol. 2010;48: 530-537.
-
(2010)
J Mol Cell Cardiol.
, vol.48
, pp. 530-537
-
-
Shamhart, P.E.1
Meszaros, J.G.2
-
36
-
-
0024319420
-
Cardiac interstitium in health and disease: The fibrillar collagen network
-
Weber KT. Cardiac interstitium in health and disease: The fibrillar collagen network. J Am Coll Cardiol. 1989;13:1637-1652.
-
(1989)
J Am Coll Cardiol.
, vol.13
, pp. 1637-1652
-
-
Weber, K.T.1
-
37
-
-
0032992589
-
Left and right ventricular collagen type I/III ratios and remodeling post-myocardial infarction
-
Wei S, Chow LT, Shum IO, Qin L, Sanderson JE. Left and right ventricular collagen type I/III ratios and remodeling post-myocardial infarction. J Card Fail. 1999;5:117-126.
-
(1999)
J Card Fail.
, vol.5
, pp. 117-126
-
-
Wei, S.1
Chow, L.T.2
Shum, I.O.3
Qin, L.4
Sanderson, J.E.5
-
38
-
-
4444229005
-
Increased collagen type i synthesis in patients with heart failure of hypertensive origin: Relation to myocardial fibrosis
-
Querejeta R, Lpez B, Gonzlez A, Snchez E, Larman M, Martnez Ubago JL, Dez J. Increased collagen type I synthesis in patients with heart failure of hypertensive origin: Relation to myocardial fibrosis. Circulation. 2004;110:1263-1268.
-
(2004)
Circulation.
, vol.110
, pp. 1263-1268
-
-
Querejeta, R.1
Lpez, B.2
Gonzlez, A.3
Snchez, E.4
Larman, M.5
Martnez Ubago, J.L.6
Dez, J.7
-
39
-
-
0034636189
-
Serum carboxy-terminal propeptide of procollagen type i is a marker of myocardial fibrosis in hypertensive heart disease
-
Querejeta R, Varo N, Lpez B, Larman M, Artiano E, Etayo JC, Martnez Ubago JL, Gutierrez-Stampa M, Emparanza JI, Gil MJ, Monreal I, Mindn JP, Dez J. Serum carboxy-terminal propeptide of procollagen type I is a marker of myocardial fibrosis in hypertensive heart disease. Circulation. 2000;101:1729-1735.
-
(2000)
Circulation.
, vol.101
, pp. 1729-1735
-
-
Querejeta, R.1
Varo, N.2
Lpez, B.3
Larman, M.4
Artiano, E.5
Etayo, J.C.6
Martnez Ubago, J.L.7
Gutierrez-Stampa, M.8
Emparanza, J.I.9
Gil, M.J.10
Monreal, I.11
Mindn, J.P.12
Dez, J.13
-
40
-
-
23344440581
-
The use of collagen-derived serum peptides for the clinical assessment of hypertensive heart disease
-
Lpez B, Gonzlez A, Querejeta R, Dez J. The use of collagen-derived serum peptides for the clinical assessment of hypertensive heart disease. J Hypertens. 2005;23:1445-1451.
-
(2005)
J Hypertens.
, vol.23
, pp. 1445-1451
-
-
Lpez, B.1
Gonzlez, A.2
Querejeta, R.3
Dez, J.4
-
41
-
-
77649275593
-
Diagnostic approaches for diabetic cardiomyopathy and myocardial fibrosis
-
Maya L, Villarreal FJ. Diagnostic approaches for diabetic cardiomyopathy and myocardial fibrosis. J Mol Cell Cardiol. 2010;48:524-529.
-
(2010)
J Mol Cell Cardiol.
, vol.48
, pp. 524-529
-
-
Maya, L.1
Villarreal, F.J.2
-
42
-
-
27944453170
-
Myocardial collagen turnover in normotensive obese patients: Relation to insulin resistance
-
Quilliot D, Alla F, Bhme P, Bruntz JF, Hammadi M, Dousset B, Ziegler O, Zannad F. Myocardial collagen turnover in normotensive obese patients: Relation to insulin resistance. Int J Obes (Lond). 2005;29:1321-1328.
-
(2005)
Int J Obes (Lond).
, vol.29
, pp. 1321-1328
-
-
Quilliot, D.1
Alla, F.2
Bhme, P.3
Bruntz, J.F.4
Hammadi, M.5
Dousset, B.6
Ziegler, O.7
Zannad, F.8
-
43
-
-
84555204713
-
Association of galectin-3 and fibrosis markers with long-term cardiovascular outcomes in patients with heart failure, left ventricular dysfunction, and dyssynchrony: Insights from the CARE-HF (Cardiac Resynchronization in Heart Failure) trial
-
Lopez-Andrs N, Rossignol P, Iraqi W, Fay R, Nue J, Ghio S, Cleland JG, Zannad F, Lacolley P. Association of galectin-3 and fibrosis markers with long-term cardiovascular outcomes in patients with heart failure, left ventricular dysfunction, and dyssynchrony: Insights from the CARE-HF (Cardiac Resynchronization in Heart Failure) trial. Eur J Heart Fail. 2012;14:74-81.
-
(2012)
Eur J Heart Fail.
, vol.14
, pp. 74-81
-
-
Lopez-Andrs, N.1
Rossignol, P.2
Iraqi, W.3
Fay, R.4
Nue, J.5
Ghio, S.6
Cleland, J.G.7
Zannad, F.8
Lacolley, P.9
-
44
-
-
34648843625
-
Mechanisms of cardiac fibrosis in hypertension
-
Dez J. Mechanisms of cardiac fibrosis in hypertension. J Clin Hypertens (Greenwich). 2007;9:546-550.
-
(2007)
J Clin Hypertens (Greenwich).
, vol.9
, pp. 546-550
-
-
Dez, J.1
-
45
-
-
0028920377
-
Measuring extracellular matrix turnover in the serum of patients with idiopathic or ischemic dilated cardiomyopathy and impact on diagnosis and prognosis
-
Klappacher G, Franzen P, Haab D, Mehrabi M, Binder M, Plesch K, Pacher R, Grimm M, Pribill I, Eichler HG. Measuring extracellular matrix turnover in the serum of patients with idiopathic or ischemic dilated cardiomyopathy and impact on diagnosis and prognosis. Am J Cardiol. 1995;75:913-918.
-
(1995)
Am J Cardiol.
, vol.75
, pp. 913-918
-
-
Klappacher, G.1
Franzen, P.2
Haab, D.3
Mehrabi, M.4
Binder, M.5
Plesch, K.6
Pacher, R.7
Grimm, M.8
Pribill, I.9
Eichler, H.G.10
-
48
-
-
0026047293
-
Mac-2-binding glycoproteins. Putative ligands for a cytosolic beta-galactoside lectin
-
Rosenberg I, Cherayil BJ, Isselbacher KJ, Pillai S. Mac-2-binding glycoproteins. Putative ligands for a cytosolic beta-galactoside lectin. J Biol Chem. 1991;266:18731-18736.
-
(1991)
J Biol Chem.
, vol.266
, pp. 18731-18736
-
-
Rosenberg, I.1
Cherayil, B.J.2
Isselbacher, K.J.3
Pillai, S.4
-
49
-
-
0026673762
-
Binding specificity of a baby hamster kidney lectin for H type i and II chains, polylactosamine glycans, and appropriately glycosylated forms of laminin and fibronectin
-
Sato S, Hughes RC. Binding specificity of a baby hamster kidney lectin for H type I and II chains, polylactosamine glycans, and appropriately glycosylated forms of laminin and fibronectin. J Biol Chem. 1992;267:6983-6990.
-
(1992)
J Biol Chem.
, vol.267
, pp. 6983-6990
-
-
Sato, S.1
Hughes, R.C.2
-
50
-
-
84866729958
-
Galectin-3, a marker of cardiac fibrosis, predicts incident heart failure in the community
-
Ho JE, Liu C, Lyass A, Courchesne P, Pencina MJ, Vasan RS, Larson MG, Levy D. Galectin-3, a marker of cardiac fibrosis, predicts incident heart failure in the community. J Am Coll Cardiol. 2012;60:1249-1256.
-
(2012)
J Am Coll Cardiol.
, vol.60
, pp. 1249-1256
-
-
Ho, J.E.1
Liu, C.2
Lyass, A.3
Courchesne, P.4
Pencina, M.J.5
Vasan, R.S.6
Larson, M.G.7
Levy, D.8
-
51
-
-
84885044150
-
Serial measurement of galectin-3 in patients with chronic heart failure: Results from the probnp outpatient tailored chronic heart failure therapy (protect) study
-
Motiwala SR, Szymonifka J, Belcher A, Weiner RB, Baggish AL, Sluss P, Gaggin HK, Bhardwaj A, Januzzi JL. Serial measurement of galectin-3 in patients with chronic heart failure: Results from the ProBNP Outpatient Tailored Chronic Heart Failure Therapy (PROTECT) study. Eur J Heart Fail. 2013;15:1157-1163.
-
(2013)
Eur J Heart Fail.
, vol.15
, pp. 1157-1163
-
-
Motiwala, S.R.1
Szymonifka, J.2
Belcher, A.3
Weiner, R.B.4
Baggish, A.L.5
Sluss, P.6
Gaggin, H.K.7
Bhardwaj, A.8
Januzzi, J.L.9
-
52
-
-
33748415221
-
Utility of amino-terminal pro-brain natriuretic peptide, galectin-3, and apelin for the evaluation of patients with acute heart failure
-
Van Kimmenade RR, Januzzi JL Jr, Ellinor PT, Sharma UC, Bakker JA, Low AF, Martinez A, Crijns HJ, MacRae CA, Menheere PP, Pinto YM. Utility of amino-terminal pro-brain natriuretic peptide, galectin-3, and apelin for the evaluation of patients with acute heart failure. J Am Coll Cardiol. 2006;48:1217-1224.
-
(2006)
J Am Coll Cardiol.
, vol.48
, pp. 1217-1224
-
-
Van Kimmenade, R.R.1
Januzzi Jr., J.L.2
Ellinor, P.T.3
Sharma, U.C.4
Bakker, J.A.5
Low, A.F.6
Martinez, A.7
Crijns, H.J.8
Macrae, C.A.9
Menheere, P.P.10
Pinto, Y.M.11
-
53
-
-
20844462878
-
Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction
-
Sharma UC, Pokharel S, Van Brakel TJ, Van Berlo JH, Cleutjens JP, Schroen B, Andr S, Crijns HJ, Gabius HJ, Maessen J, Pinto YM. Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction. Circulation. 2004;110:3121-3128.
-
(2004)
Circulation.
, vol.110
, pp. 3121-3128
-
-
Sharma, U.C.1
Pokharel, S.2
Van Brakel, T.J.3
Van Berlo, J.H.4
Cleutjens, J.P.5
Schroen, B.6
Andr, S.7
Crijns, H.J.8
Gabius, H.J.9
Maessen, J.10
Pinto, Y.M.11
-
54
-
-
84861348367
-
Novel therapies in acute and chronic heart failure
-
Aronson D, Krum H. Novel therapies in acute and chronic heart failure. Pharmacol Ther. 2012;135:1-17.
-
(2012)
Pharmacol Ther.
, vol.135
, pp. 1-17
-
-
Aronson, D.1
Krum, H.2
-
55
-
-
4344632810
-
Advanced glycation end product cross-linking: Pathophysiologic role and therapeutic target in cardiovascular disease
-
quiz 150
-
Zieman S, Kass D. Advanced glycation end product cross-linking: Pathophysiologic role and therapeutic target in cardiovascular disease. Congest Heart Fail. 2004;10:144-149; quiz 150.
-
(2004)
Congest Heart Fail.
, vol.10
, pp. 144-149
-
-
Zieman, S.1
Kass, D.2
-
56
-
-
33746920337
-
Advanced glycation end products: Sparking the development of diabetic vascular injury
-
Goldin A, Beckman JA, Schmidt AM, Creager MA. Advanced glycation end products: Sparking the development of diabetic vascular injury. Circulation. 2006;114:597-605.
-
(2006)
Circulation.
, vol.114
, pp. 597-605
-
-
Goldin, A.1
Beckman, J.A.2
Schmidt, A.M.3
Creager, M.A.4
-
57
-
-
34548821888
-
LV systolic impairment in patients with asymptomatic coronary heart disease and type 1 diabetes is related to coronary atherosclerosis, glycaemic control and advanced glycation endproducts
-
Steine K, Larsen JR, Stugaard M, Berg TJ, Brekke M, Dahl-Jrgensen K. LV systolic impairment in patients with asymptomatic coronary heart disease and type 1 diabetes is related to coronary atherosclerosis, glycaemic control and advanced glycation endproducts. Eur J Heart Fail. 2007;9:1044-1050.
-
(2007)
Eur J Heart Fail.
, vol.9
, pp. 1044-1050
-
-
Steine, K.1
Larsen, J.R.2
Stugaard, M.3
Berg, T.J.4
Brekke, M.5
Dahl-Jrgensen, K.6
-
58
-
-
0033054547
-
Serum levels of advanced glycation end products are associated with left ventricular diastolic function in patients with type 1 diabetes
-
Berg TJ, Snorgaard O, Faber J, Torjesen PA, Hildebrandt P, Mehlsen J, Hanssen KF. Serum levels of advanced glycation end products are associated with left ventricular diastolic function in patients with type 1 diabetes. Diabetes Care. 1999;22:1186-1190.
-
(1999)
Diabetes Care.
, vol.22
, pp. 1186-1190
-
-
Berg, T.J.1
Snorgaard, O.2
Faber, J.3
Torjesen, P.A.4
Hildebrandt, P.5
Mehlsen, J.6
Hanssen, K.F.7
-
59
-
-
83455245483
-
Plasma levels of matrix metalloproteinases and their inhibitors in hypertension: A systematic review and meta-analysis
-
Marchesi C, Dentali F, Nicolini E, Maresca AM, Tayebjee MH, Franz M, Guasti L, Venco A, Schiffrin EL, Lip GY, Grandi AM. Plasma levels of matrix metalloproteinases and their inhibitors in hypertension: A systematic review and meta-analysis. J Hypertens. 2012;30:3-16.
-
(2012)
J Hypertens.
, vol.30
, pp. 3-16
-
-
Marchesi, C.1
Dentali, F.2
Nicolini, E.3
Maresca, A.M.4
Tayebjee, M.H.5
Franz, M.6
Guasti, L.7
Venco, A.8
Schiffrin, E.L.9
Lip, G.Y.10
Grandi, A.M.11
-
60
-
-
33748283150
-
Plasma matrix metalloproteinase-9 level is correlated with left ventricular volumes and ejection fraction in patients with heart failure
-
Yan AT, Yan RT, Spinale FG, Afzal R, Gunasinghe HR, Arnold M, Demers C, McKelvie RS, Liu PP. Plasma matrix metalloproteinase-9 level is correlated with left ventricular volumes and ejection fraction in patients with heart failure. J Card Fail. 2006;12:514-519.
-
(2006)
J Card Fail.
, vol.12
, pp. 514-519
-
-
Yan, A.T.1
Yan, R.T.2
Spinale, F.G.3
Afzal, R.4
Gunasinghe, H.R.5
Arnold, M.6
Demers, C.7
McKelvie, R.S.8
Liu, P.P.9
-
61
-
-
33748479022
-
Specific temporal profile of matrix metalloproteinase release occurs in patients after myocardial infarction: Relation to left ventricular remodeling
-
Webb CS, Bonnema DD, Ahmed SH, Leonardi AH, McClure CD, Clark LL, Stroud RE, Corn WC, Finklea L, Zile MR, Spinale FG. Specific temporal profile of matrix metalloproteinase release occurs in patients after myocardial infarction: Relation to left ventricular remodeling. Circulation. 2006;114:1020-1027.
-
(2006)
Circulation.
, vol.114
, pp. 1020-1027
-
-
Webb, C.S.1
Bonnema, D.D.2
Ahmed, S.H.3
Leonardi, A.H.4
McClure, C.D.5
Clark, L.L.6
Stroud, R.E.7
Corn, W.C.8
Finklea, L.9
Zile, M.R.10
Spinale, F.G.11
-
64
-
-
34250017173
-
Effects of timed administration of doxycycline or methylprednisolone on post-myocardial infarction inflammation and left ventricular remodeling in the rat heart
-
Garcia RA, Go KV, Villarreal FJ. Effects of timed administration of doxycycline or methylprednisolone on post-myocardial infarction inflammation and left ventricular remodeling in the rat heart. Mol Cell Biochem. 2007;300:159-169.
-
(2007)
Mol Cell Biochem.
, vol.300
, pp. 159-169
-
-
Garcia, R.A.1
Go, K.V.2
Villarreal, F.J.3
-
65
-
-
0035731321
-
Ventricular free wall rupture in acute myocardial infarction
-
Khalil ME, Heller EN, Boctor F, Brown EJ Jr, Alhaddad IA. Ventricular free wall rupture in acute myocardial infarction. J Cardiovasc Pharmacol Ther. 2001;6:231-236.
-
(2001)
J Cardiovasc Pharmacol Ther.
, vol.6
, pp. 231-236
-
-
Khalil, M.E.1
Heller, E.N.2
Boctor, F.3
Brown Jr., E.J.4
Alhaddad, I.A.5
-
66
-
-
0028340562
-
Collagen network of the myocardium: Function, structural remodeling and regulatory mechanisms
-
Weber KT, Sun Y, Tyagi SC, Cleutjens JP. Collagen network of the myocardium: Function, structural remodeling and regulatory mechanisms. J Mol Cell Cardiol. 1994;26:279-292.
-
(1994)
J Mol Cell Cardiol.
, vol.26
, pp. 279-292
-
-
Weber, K.T.1
Sun, Y.2
Tyagi, S.C.3
Cleutjens, J.P.4
-
67
-
-
33745845825
-
Physiology of local renin-angiotensin systems
-
Paul M, Poyan Mehr A, Kreutz R. Physiology of local renin-angiotensin systems. Physiol Rev. 2006;86:747-803.
-
(2006)
Physiol Rev.
, vol.86
, pp. 747-803
-
-
Paul, M.1
Poyan Mehr, A.2
Kreutz, R.3
-
68
-
-
6444220362
-
The role of the renin-angiotensin-aldosterone system in heart failure
-
Unger T, Li J. The role of the renin-angiotensin-aldosterone system in heart failure. J Renin Angiotensin Aldosterone Syst. 2004;5(suppl 1):S7-S10.
-
(2004)
J Renin Angiotensin Aldosterone Syst.
, vol.5
, Issue.SUPPL. 1
, pp. 7-10
-
-
Unger, T.1
Li, J.2
-
69
-
-
4544278755
-
Diabetes mellitus, the renin-angiotensin-aldosterone system, and the heart
-
Lim HS, MacFadyen RJ, Lip GY. Diabetes mellitus, the renin-angiotensin- aldosterone system, and the heart. Arch Intern Med. 2004;164:1737-1748.
-
(2004)
Arch Intern Med.
, vol.164
, pp. 1737-1748
-
-
Lim, H.S.1
Macfadyen, R.J.2
Lip, G.Y.3
-
70
-
-
0030712898
-
Angiotensin II receptors in endothelial cells
-
Pueyo ME, Michel JB. Angiotensin II receptors in endothelial cells. Gen Pharmacol. 1997;29:691-696.
-
(1997)
Gen Pharmacol.
, vol.29
, pp. 691-696
-
-
Pueyo, M.E.1
Michel, J.B.2
-
71
-
-
0027440688
-
Identification of functional angiotensin II receptors on rat cardiac fibroblasts
-
Villarreal FJ, Kim NN, Ungab GD, Printz MP, Dillmann WH. Identification of functional angiotensin II receptors on rat cardiac fibroblasts. Circulation. 1993;88:2849-2861.
-
(1993)
Circulation.
, vol.88
, pp. 2849-2861
-
-
Villarreal, F.J.1
Kim, N.N.2
Ungab, G.D.3
Printz, M.P.4
Dillmann, W.H.5
-
72
-
-
0033033229
-
Upregulation of renin-angiotensin system during differentiation of monocytes to macrophages
-
Okamura A, Rakugi H, Ohishi M, Yanagitani Y, Takiuchi S, Moriguchi K, Fennessy PA, Higaki J, Ogihara T. Upregulation of renin-angiotensin system during differentiation of monocytes to macrophages. J Hypertens. 1999;17:537-545.
-
(1999)
J Hypertens.
, vol.17
, pp. 537-545
-
-
Okamura, A.1
Rakugi, H.2
Ohishi, M.3
Yanagitani, Y.4
Takiuchi, S.5
Moriguchi, K.6
Fennessy, P.A.7
Higaki, J.8
Ogihara, T.9
-
73
-
-
0028075696
-
Vascular smooth-muscle cells contain AT1 angiotensin receptors coupled to phospholipase D activation
-
Freeman EJ, Tallant EA. Vascular smooth-muscle cells contain AT1 angiotensin receptors coupled to phospholipase D activation. Biochem J. 1994;304 (pt 2):543-548.
-
(1994)
Biochem J.
, vol.304
, Issue.PART 2
, pp. 543-548
-
-
Freeman, E.J.1
Tallant, E.A.2
-
75
-
-
0034070354
-
Angiotensin II directly increases transforming growth factor beta1 and osteopontin and indirectly affects collagen mRNA expression in the human heart
-
Kupfahl C, Pink D, Friedrich K, Zurbrgg HR, Neuss M, Warnecke C, Fielitz J, Graf K, Fleck E, Regitz-Zagrosek V. Angiotensin II directly increases transforming growth factor beta1 and osteopontin and indirectly affects collagen mRNA expression in the human heart. Cardiovasc Res. 2000;46:463-475.
-
(2000)
Cardiovasc Res.
, vol.46
, pp. 463-475
-
-
Kupfahl, C.1
Pink, D.2
Friedrich, K.3
Zurbrgg, H.R.4
Neuss, M.5
Warnecke, C.6
Fielitz, J.7
Graf, K.8
Fleck, E.9
Regitz-Zagrosek, V.10
-
76
-
-
78049492323
-
Minireview: Aldosterone and mineralocorticoid receptors: Past, present, and future
-
Funder JW. Minireview: Aldosterone and mineralocorticoid receptors: Past, present, and future. Endocrinology. 2010;151:5098-5102.
-
(2010)
Endocrinology.
, vol.151
, pp. 5098-5102
-
-
Funder, J.W.1
-
77
-
-
34248575767
-
Mineralocorticoid receptor activation and cardiac fibrosis
-
Young MJ, Lam EY, Rickard AJ. Mineralocorticoid receptor activation and cardiac fibrosis. Clin Sci (Lond). 2007;112:467-475.
-
(2007)
Clin Sci (Lond).
, vol.112
, pp. 467-475
-
-
Young, M.J.1
Lam, E.Y.2
Rickard, A.J.3
-
78
-
-
41749123049
-
Activation of the intracellular renin-angiotensin system in cardiac fibroblasts by high glucose: Role in extracellular matrix production
-
Singh VP, Baker KM, Kumar R. Activation of the intracellular renin-angiotensin system in cardiac fibroblasts by high glucose: Role in extracellular matrix production. Am J Physiol Heart Circ Physiol. 2008;294:H1675-H1684.
-
(2008)
Am J Physiol Heart Circ Physiol.
, vol.294
, pp. 1675-1684
-
-
Singh, V.P.1
Baker, K.M.2
Kumar, R.3
-
79
-
-
0035383430
-
Angiotensin II-induced stimulation of collagen secretion and production in cardiac fibroblasts is mediated via angiotensin II subtype 1 receptors
-
Lijnen PJ, Petrov VV, Fagard RH. Angiotensin II-induced stimulation of collagen secretion and production in cardiac fibroblasts is mediated via angiotensin II subtype 1 receptors. J Renin Angiotensin Aldosterone Syst. 2001;2:117-122.
-
(2001)
J Renin Angiotensin Aldosterone Syst.
, vol.2
, pp. 117-122
-
-
Lijnen, P.J.1
Petrov, V.V.2
Fagard, R.H.3
-
80
-
-
0028789457
-
Angiotensin II stimulates the autocrine production of transforming growth factor-beta 1 in adult rat cardiac fibroblasts
-
Lee AA, Dillmann WH, McCulloch AD, Villarreal FJ. Angiotensin II stimulates the autocrine production of transforming growth factor-beta 1 in adult rat cardiac fibroblasts. J Mol Cell Cardiol. 1995;27:2347-2357.
-
(1995)
J Mol Cell Cardiol.
, vol.27
, pp. 2347-2357
-
-
Lee, A.A.1
Dillmann, W.H.2
McCulloch, A.D.3
Villarreal, F.J.4
-
81
-
-
0029774377
-
Advanced hypertensive heart disease in spontaneously hypertensive rats. Lisinopril-mediated regression of myocardial fibrosis
-
Brilla CG, Matsubara L, Weber KT. Advanced hypertensive heart disease in spontaneously hypertensive rats. Lisinopril-mediated regression of myocardial fibrosis. Hypertension. 1996;28:269-275.
-
(1996)
Hypertension.
, vol.28
, pp. 269-275
-
-
Brilla, C.G.1
Matsubara, L.2
Weber, K.T.3
-
82
-
-
79959442500
-
Chronic losartan administration reduces mortality and preserves cardiac but not skeletal muscle function in dystrophic mice
-
Bish LT, Yarchoan M, Sleeper MM, Gazzara JA, Morine KJ, Acosta P, Barton ER, Sweeney HL. Chronic losartan administration reduces mortality and preserves cardiac but not skeletal muscle function in dystrophic mice. PLoS One. 2011;6:e20856.
-
(2011)
PLoS One.
, vol.6
-
-
Bish, L.T.1
Yarchoan, M.2
Sleeper, M.M.3
Gazzara, J.A.4
Morine, K.J.5
Acosta, P.6
Barton, E.R.7
Sweeney, H.L.8
-
83
-
-
0034687149
-
Lisinopril-mediated regression of myocardial fibrosis in patients with hypertensive heart disease
-
Brilla CG, Funck RC, Rupp H. Lisinopril-mediated regression of myocardial fibrosis in patients with hypertensive heart disease. Circulation. 2000;102:1388-1393.
-
(2000)
Circulation.
, vol.102
, pp. 1388-1393
-
-
Brilla, C.G.1
Funck, R.C.2
Rupp, H.3
-
84
-
-
0033082589
-
Regulation of cardiac fibroblast extracellular matrix production by bradykinin and nitric oxide
-
Kim NN, Villegas S, Summerour SR, Villarreal FJ. Regulation of cardiac fibroblast extracellular matrix production by bradykinin and nitric oxide. J Mol Cell Cardiol. 1999;31:457-466.
-
(1999)
J Mol Cell Cardiol.
, vol.31
, pp. 457-466
-
-
Kim, N.N.1
Villegas, S.2
Summerour, S.R.3
Villarreal, F.J.4
-
85
-
-
0001739436
-
Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell
-
Leri A, Claudio PP, Li Q, Wang X, Reiss K, Wang S, Malhotra A, Kajstura J, Anversa P. Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell. J Clin Invest. 1998;101:1326-1342.
-
(1998)
J Clin Invest.
, vol.101
, pp. 1326-1342
-
-
Leri, A.1
Claudio, P.P.2
Li, Q.3
Wang, X.4
Reiss, K.5
Wang, S.6
Malhotra, A.7
Kajstura, J.8
Anversa, P.9
-
86
-
-
0037134412
-
Angiotensin II receptor-independent antiinflammatory and antiaggregatory properties of losartan: Role of the active metabolite EXP3179
-
Krmer C, Sunkomat J, Witte J, Luchtefeld M, Walden M, Schmidt B, Tsikas D, Bger RH, Forssmann WG, Drexler H, Schieffer B. Angiotensin II receptor-independent antiinflammatory and antiaggregatory properties of losartan: Role of the active metabolite EXP3179. Circ Res. 2002;90:770-776.
-
(2002)
Circ Res.
, vol.90
, pp. 770-776
-
-
Krmer, C.1
Sunkomat, J.2
Witte, J.3
Luchtefeld, M.4
Walden, M.5
Schmidt, B.6
Tsikas, D.7
Bger, R.H.8
Forssmann, W.G.9
Drexler, H.10
Schieffer, B.11
-
87
-
-
0242366540
-
Aldosterone/salt induces renal inflammation and fibrosis in hypertensive rats
-
Blasi ER, Rocha R, Rudolph AE, Blomme EA, Polly ML, McMahon EG. Aldosterone/salt induces renal inflammation and fibrosis in hypertensive rats. Kidney Int. 2003;63:1791-1800.
-
(2003)
Kidney Int.
, vol.63
, pp. 1791-1800
-
-
Blasi, E.R.1
Rocha, R.2
Rudolph, A.E.3
Blomme, E.A.4
Polly, M.L.5
McMahon, E.G.6
-
88
-
-
79960984168
-
Results of the randomized aldosterone antagonism in heart failure with preserved ejection fraction trial (raam-pef)
-
Deswal A, Richardson P, Bozkurt B, Mann DL. Results of the Randomized Aldosterone Antagonism in Heart Failure with Preserved Ejection Fraction trial (RAAM-PEF). J Card Fail. 2011;17:634-642.
-
(2011)
J Card Fail.
, vol.17
, pp. 634-642
-
-
Deswal, A.1
Richardson, P.2
Bozkurt, B.3
Mann, D.L.4
-
89
-
-
78149424364
-
Effect of spironolactone on left ventricular systolic and diastolic function in patients with early stage chronic kidney disease
-
Edwards NC, Ferro CJ, Kirkwood H, Chue CD, Young AA, Stewart PM, Steeds RP, Townend JN. Effect of spironolactone on left ventricular systolic and diastolic function in patients with early stage chronic kidney disease. Am J Cardiol. 2010;106:1505-1511.
-
(2010)
Am J Cardiol.
, vol.106
, pp. 1505-1511
-
-
Edwards, N.C.1
Ferro, C.J.2
Kirkwood, H.3
Chue, C.D.4
Young, A.A.5
Stewart, P.M.6
Steeds, R.P.7
Townend, J.N.8
-
90
-
-
0032871720
-
The cellular and physiologic effects of beta blockers in heart failure
-
Sabbah HN. The cellular and physiologic effects of beta blockers in heart failure. Clin Cardiol. 1999;22(suppl 5):V16-V20.
-
(1999)
Clin Cardiol.
, vol.22
, Issue.SUPPL. 5
, pp. 16-20
-
-
Sabbah, H.N.1
-
91
-
-
0034620523
-
Beta-adrenergic receptor blockade in chronic heart failure
-
Bristow MR. beta-adrenergic receptor blockade in chronic heart failure. Circulation. 2000;101:558-569.
-
(2000)
Circulation.
, vol.101
, pp. 558-569
-
-
Bristow, M.R.1
-
93
-
-
0033910521
-
Effect of carvedilol in comparison with metoprolol on myocardial collagen postinfarction
-
Wei S, Chow LT, Sanderson JE. Effect of carvedilol in comparison with metoprolol on myocardial collagen postinfarction. J Am Coll Cardiol. 2000;36:276-281.
-
(2000)
J Am Coll Cardiol.
, vol.36
, pp. 276-281
-
-
Wei, S.1
Chow, L.T.2
Sanderson, J.E.3
-
94
-
-
0028981194
-
Endothelin ETA and ETB receptors cause vasoconstriction of human resistance and capacitance vessels in vivo
-
Haynes WG, Strachan FE, Webb DJ. Endothelin ETA and ETB receptors cause vasoconstriction of human resistance and capacitance vessels in vivo. Circulation. 1995;92:357-363.
-
(1995)
Circulation.
, vol.92
, pp. 357-363
-
-
Haynes, W.G.1
Strachan, F.E.2
Webb, D.J.3
-
95
-
-
85047675578
-
Endothelin receptors in cultured adult rat cardiac fibroblasts
-
Katwa LC, Guarda E, Weber KT. Endothelin receptors in cultured adult rat cardiac fibroblasts. Cardiovasc Res. 1993;27:2125-2129.
-
(1993)
Cardiovasc Res.
, vol.27
, pp. 2125-2129
-
-
Katwa, L.C.1
Guarda, E.2
Weber, K.T.3
-
96
-
-
84876706037
-
A review of current and novel therapies for idiopathic pulmonary fibrosis
-
Rafii R, Juarez MM, Albertson TE, Chan AL. A review of current and novel therapies for idiopathic pulmonary fibrosis. J Thorac Dis. 2013;5:48-73.
-
(2013)
J Thorac Dis.
, vol.5
, pp. 48-73
-
-
Rafii, R.1
Juarez, M.M.2
Albertson, T.E.3
Chan, A.L.4
-
97
-
-
0029914353
-
Respective role of humoral factors and blood pressure in cardiac remodeling of DOCA hypertensive rats
-
Karam H, Heudes D, Hess P, Gonzales MF, Lffler BM, Clozel M, Clozel JP. Respective role of humoral factors and blood pressure in cardiac remodeling of DOCA hypertensive rats. Cardiovasc Res. 1996;31:287-295.
-
(1996)
Cardiovasc Res.
, vol.31
, pp. 287-295
-
-
Karam, H.1
Heudes, D.2
Hess, P.3
Gonzales, M.F.4
Lffler, B.M.5
Clozel, M.6
Clozel, J.P.7
-
98
-
-
0035895333
-
Myocardial fibrosis in DOCA-salt hypertensive rats: Effect of endothelin ET(A) receptor antagonism
-
Ammarguellat F, Larouche I, Schiffrin EL. Myocardial fibrosis in DOCA-salt hypertensive rats: Effect of endothelin ET(A) receptor antagonism. Circulation. 2001;103:319-324.
-
(2001)
Circulation.
, vol.103
, pp. 319-324
-
-
Ammarguellat, F.1
Larouche, I.2
Schiffrin, E.L.3
-
99
-
-
33744942636
-
Clinical trials of endothelin antagonists in heart failure: A question of dose
-
Kelland NF, Webb DJ. Clinical trials of endothelin antagonists in heart failure: A question of dose Exp Biol Med (Maywood). 2006;231: 696-699.
-
(2006)
Exp Biol Med (Maywood).
, vol.231
, pp. 696-699
-
-
Kelland, N.F.1
Webb, D.J.2
-
100
-
-
12944329901
-
Cardiac fibrosis in mice lacking brain natriuretic peptide
-
Tamura N, Ogawa Y, Chusho H, Nakamura K, Nakao K, Suda M, Kasahara M, Hashimoto R, Katsuura G, Mukoyama M, Itoh H, Saito Y, Tanaka I, Otani H, Katsuki M. Cardiac fibrosis in mice lacking brain natriuretic peptide. Proc Natl Acad Sci USA. 2000;97:4239-4244.
-
(2000)
Proc Natl Acad Sci USA.
, vol.97
, pp. 4239-4244
-
-
Tamura, N.1
Ogawa, Y.2
Chusho, H.3
Nakamura, K.4
Nakao, K.5
Suda, M.6
Kasahara, M.7
Hashimoto, R.8
Katsuura, G.9
Mukoyama, M.10
Itoh, H.11
Saito, Y.12
Tanaka, I.13
Otani, H.14
Katsuki, M.15
-
101
-
-
0036213605
-
Progressive cardiac hypertrophy and dysfunction in atrial natriuretic peptide receptor (GC-A) deficient mice
-
Kuhn M, Holtwick R, Baba HA, Perriard JC, Schmitz W, Ehler E. Progressive cardiac hypertrophy and dysfunction in atrial natriuretic peptide receptor (GC-A) deficient mice. Heart. 2002;87:368-374.
-
(2002)
Heart.
, vol.87
, pp. 368-374
-
-
Kuhn, M.1
Holtwick, R.2
Baba, H.A.3
Perriard, J.C.4
Schmitz, W.5
Ehler, E.6
-
102
-
-
0036954729
-
Brain natriuretic peptide is produced in cardiac fibroblasts and induces matrix metalloproteinases
-
Tsuruda T, Boerrigter G, Huntley BK, Noser JA, Cataliotti A, Costello-Boerrigter LC, Chen HH, Burnett JC Jr. Brain natriuretic peptide is produced in cardiac fibroblasts and induces matrix metalloproteinases. Circ Res. 2002;91:1127-1134.
-
(2002)
Circ Res.
, vol.91
, pp. 1127-1134
-
-
Tsuruda, T.1
Boerrigter, G.2
Huntley, B.K.3
Noser, J.A.4
Cataliotti, A.5
Costello-Boerrigter, L.C.6
Chen, H.H.7
Burnett Jr., J.C.8
-
103
-
-
79960090547
-
Effect of nesiritide in patients with acute decompensated heart failure
-
OConnor CM, Starling RC, Hernandez AF, et al. Effect of nesiritide in patients with acute decompensated heart failure. N Engl J Med. 2011;365:32-43.
-
(2011)
N Engl J Med.
, vol.365
, pp. 32-43
-
-
Oconnor, C.M.1
Starling, R.C.2
Hernandez, A.F.3
-
104
-
-
84875580118
-
Neutral endopeptidase inhibition and the natriuretic peptide system: An evolving strategy in cardiovascular therapeutics
-
Mangiafico S, Costello-Boerrigter LC, Andersen IA, Cataliotti A, Burnett JC Jr. Neutral endopeptidase inhibition and the natriuretic peptide system: An evolving strategy in cardiovascular therapeutics. Eur Heart J. 2013;34:886-893c.
-
(2013)
Eur Heart J.
, vol.34
, pp. 886-893
-
-
Mangiafico, S.1
Costello-Boerrigter, L.C.2
Andersen, I.A.3
Cataliotti, A.4
Burnett Jr., J.C.5
-
105
-
-
0036084359
-
TGF-beta antagonists why suppress a tumor suppressor
-
Akhurst RJ. TGF-beta antagonists: Why suppress a tumor suppressor J Clin Invest. 2002;109:1533-1536.
-
(2002)
J Clin Invest.
, vol.109
, pp. 1533-1536
-
-
Akhurst, R.J.1
-
106
-
-
79956341531
-
Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): Two randomised trials
-
CAPACITY Study Group
-
Noble PW, Albera C, Bradford WZ, Costabel U, Glassberg MK, Kardatzke D, King TE Jr, Lancaster L, Sahn SA, Szwarcberg J, Valeyre D, du Bois RM; CAPACITY Study Group. Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): Two randomised trials. Lancet. 2011;377:1760-1769.
-
(2011)
Lancet.
, vol.377
, pp. 1760-1769
-
-
Noble, P.W.1
Albera, C.2
Bradford, W.Z.3
Costabel, U.4
Glassberg, M.K.5
Kardatzke, D.6
King Jr., T.E.7
Lancaster, L.8
Sahn, S.A.9
Szwarcberg, J.10
Valeyre, D.11
Du Bois, R.M.12
-
107
-
-
41149162536
-
Effects of three anti-TNF-alpha drugs: Etanercept, infliximab and pirfenidone on release of TNF-alpha in medium and TNF-alpha associated with the cell in vitro
-
Grattendick KJ, Nakashima JM, Feng L, Giri SN, Margolin SB. Effects of three anti-TNF-alpha drugs: Etanercept, infliximab and pirfenidone on release of TNF-alpha in medium and TNF-alpha associated with the cell in vitro. Int Immunopharmacol. 2008;8:679-687.
-
(2008)
Int Immunopharmacol.
, vol.8
, pp. 679-687
-
-
Grattendick, K.J.1
Nakashima, J.M.2
Feng, L.3
Giri, S.N.4
Margolin, S.B.5
-
108
-
-
3543071795
-
Pirfenidone attenuates expression of HSP47 in murine bleomycin-induced pulmonary fibrosis
-
Kakugawa T, Mukae H, Hayashi T, Ishii H, Abe K, Fujii T, Oku H, Miyazaki M, Kadota J, Kohno S. Pirfenidone attenuates expression of HSP47 in murine bleomycin-induced pulmonary fibrosis. Eur Respir J. 2004;24:57-65.
-
(2004)
Eur Respir J.
, vol.24
, pp. 57-65
-
-
Kakugawa, T.1
Mukae, H.2
Hayashi, T.3
Ishii, H.4
Abe, K.5
Fujii, T.6
Oku, H.7
Miyazaki, M.8
Kadota, J.9
Kohno, S.10
-
109
-
-
0036185827
-
Attenuation of cardiac fibrosis by pirfenidone and amiloride in DOCA-salt hypertensive rats
-
Mirkovic S, Seymour AM, Fenning A, Strachan A, Margolin SB, Taylor SM, Brown L. Attenuation of cardiac fibrosis by pirfenidone and amiloride in DOCA-salt hypertensive rats. Br J Pharmacol. 2002;135:961-968.
-
(2002)
Br J Pharmacol.
, vol.135
, pp. 961-968
-
-
Mirkovic, S.1
Seymour, A.M.2
Fenning, A.3
Strachan, A.4
Margolin, S.B.5
Taylor, S.M.6
Brown, L.7
-
110
-
-
0034946204
-
Reversal of cardiac and renal fibrosis by pirfenidone and spironolactone in streptozotocin-diabetic rats
-
Miric G, Dallemagne C, Endre Z, Margolin S, Taylor SM, Brown L. Reversal of cardiac and renal fibrosis by pirfenidone and spironolactone in streptozotocin-diabetic rats. Br J Pharmacol. 2001;133:687-694.
-
(2001)
Br J Pharmacol.
, vol.133
, pp. 687-694
-
-
Miric, G.1
Dallemagne, C.2
Endre, Z.3
Margolin, S.4
Taylor, S.M.5
Brown, L.6
-
111
-
-
79955565441
-
Fibrosis is regulated by Th2 and Th17 responses and by dynamic interactions between fibroblasts and macrophages
-
Barron L, Wynn TA. Fibrosis is regulated by Th2 and Th17 responses and by dynamic interactions between fibroblasts and macrophages. Am J Physiol Gastrointest Liver Physiol. 2011;300:G723-G728.
-
(2011)
Am J Physiol Gastrointest Liver Physiol.
, vol.300
, pp. 723-728
-
-
Barron, L.1
Wynn, T.A.2
-
112
-
-
59449107442
-
Myocardial repair/remodelling following infarction: Roles of local factors
-
Sun Y. Myocardial repair/remodelling following infarction: Roles of local factors. Cardiovasc Res. 2009;81:482-490.
-
(2009)
Cardiovasc Res.
, vol.81
, pp. 482-490
-
-
Sun, Y.1
-
113
-
-
0034688195
-
Vitamin e supplementation and cardiovascular events in high-risk patients
-
The Heart Outcomes Prevention Evaluation Study Investigators
-
Yusuf S, Dagenais G, Pogue J, Bosch J, Sleight P. Vitamin E supplementation and cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med. 2000;342:154-160.
-
(2000)
N Engl J Med.
, vol.342
, pp. 154-160
-
-
Yusuf, S.1
Dagenais, G.2
Pogue, J.3
Bosch, J.4
Sleight, P.5
-
114
-
-
0032827842
-
Higher levels of antioxidant defenses in enalapril-treated versus non-enalapril-treated hemodialysis patients
-
De Cavanagh EM, Ferder L, Carrasquedo F, Scrivo D, Wassermann A, Fraga CG, Inserra F. Higher levels of antioxidant defenses in enalapril-treated versus non-enalapril-treated hemodialysis patients. Am J Kidney Dis. 1999;34:445-455.
-
(1999)
Am J Kidney Dis.
, vol.34
, pp. 445-455
-
-
De Cavanagh, E.M.1
Ferder, L.2
Carrasquedo, F.3
Scrivo, D.4
Wassermann, A.5
Fraga, C.G.6
Inserra, F.7
-
115
-
-
79958830450
-
Fibrosis in endstage human heart failure: Severe changes in collagen metabolism and MMP/TIMP profiles
-
Polyakova V, Loeffler I, Hein S, Miyagawa S, Piotrowska I, Dammer S, Risteli J, Schaper J, Kostin S. Fibrosis in endstage human heart failure: Severe changes in collagen metabolism and MMP/TIMP profiles. Int J Cardiol. 2011;151:18-33.
-
(2011)
Int J Cardiol.
, vol.151
, pp. 18-33
-
-
Polyakova, V.1
Loeffler, I.2
Hein, S.3
Miyagawa, S.4
Piotrowska, I.5
Dammer, S.6
Risteli, J.7
Schaper, J.8
Kostin, S.9
-
116
-
-
77956562826
-
Tetracyclines: A pleitropic family of compounds with promising therapeutic properties. Review of the literature
-
Griffin MO, Fricovsky E, Ceballos G, Villarreal F. Tetracyclines: A pleitropic family of compounds with promising therapeutic properties. Review of the literature. Am J Physiol Cell Physiol. 2010;299:C539-C548.
-
(2010)
Am J Physiol Cell Physiol.
, vol.299
, pp. 539-548
-
-
Griffin, M.O.1
Fricovsky, E.2
Ceballos, G.3
Villarreal, F.4
-
117
-
-
31944448350
-
Doxycycline attenuated pulmonary fibrosis induced by bleomycin in mice
-
Fujita M, Ye Q, Ouchi H, Harada E, Inoshima I, Kuwano K, Nakanishi Y. Doxycycline attenuated pulmonary fibrosis induced by bleomycin in mice. Antimicrob Agents Chemother. 2006;50:739-743.
-
(2006)
Antimicrob Agents Chemother.
, vol.50
, pp. 739-743
-
-
Fujita, M.1
Ye, Q.2
Ouchi, H.3
Harada, E.4
Inoshima, I.5
Kuwano, K.6
Nakanishi, Y.7
-
118
-
-
84892682128
-
Early short-term doxycycline therapy in patients with acute myocardial infarction and left ventricular dysfunction to prevent the ominous progression to adverse remodelling: The TIPTOP trial
-
Cerisano G, Buonamici P, Valenti R, Sciagr R, Raspanti S, Santini A, Carrabba N, Dovellini EV, Romito R, Pupi A, Colonna P, Antoniucci D. Early short-term doxycycline therapy in patients with acute myocardial infarction and left ventricular dysfunction to prevent the ominous progression to adverse remodelling: The TIPTOP trial. Eur Heart J. 2014;35:184-191.
-
(2014)
Eur Heart J.
, vol.35
, pp. 184-191
-
-
Cerisano, G.1
Buonamici, P.2
Valenti, R.3
Sciagr, R.4
Raspanti, S.5
Santini, A.6
Carrabba, N.7
Dovellini, E.V.8
Romito, R.9
Pupi, A.10
Colonna, P.11
Antoniucci, D.12
-
119
-
-
0037251741
-
Cross-linking of glycated collagen in the pathogenesis of arterial and myocardial stiffening of aging and diabetes
-
Aronson D. Cross-linking of glycated collagen in the pathogenesis of arterial and myocardial stiffening of aging and diabetes. J Hypertens. 2003;21:3-12.
-
(2003)
J Hypertens.
, vol.21
, pp. 3-12
-
-
Aronson, D.1
-
120
-
-
0032949682
-
Molecular mechanisms of myocardial remodeling
-
Swynghedauw B. Molecular mechanisms of myocardial remodeling. Physiol Rev. 1999;79:215-262.
-
(1999)
Physiol Rev.
, vol.79
, pp. 215-262
-
-
Swynghedauw, B.1
-
121
-
-
0344132070
-
Novel inhibitors of advanced glycation endproducts
-
Rahbar S, Kumar Yernini K, Scott S, Gonzales N, Lalezari I. Novel inhibitors of advanced glycation endproducts. Biochem Biophys Res Commun. 1999;262:651-656.
-
(1999)
Biochem Biophys Res Commun.
, vol.262
, pp. 651-656
-
-
Rahbar, S.1
Kumar Yernini, K.2
Scott, S.3
Gonzales, N.4
Lalezari, I.5
-
122
-
-
0034646372
-
An advanced glycation endproduct cross-link breaker can reverse age-related increases in myocardial stiffness
-
Asif M, Egan J, Vasan S, Jyothirmayi GN, Masurekar MR, Lopez S, Williams C, Torres RL, Wagle D, Ulrich P, Cerami A, Brines M, Regan TJ. An advanced glycation endproduct cross-link breaker can reverse age-related increases in myocardial stiffness. Proc Natl Acad Sci USA. 2000;97:2809-2813.
-
(2000)
Proc Natl Acad Sci USA.
, vol.97
, pp. 2809-2813
-
-
Asif, M.1
Egan, J.2
Vasan, S.3
Jyothirmayi, G.N.4
Masurekar, M.R.5
Lopez, S.6
Williams, C.7
Torres, R.L.8
Wagle, D.9
Ulrich, P.10
Cerami, A.11
Brines, M.12
Regan, T.J.13
-
123
-
-
0035949502
-
Improved arterial compliance by a novel advanced glycation end-product crosslink breaker
-
Kass DA, Shapiro EP, Kawaguchi M, Capriotti AR, Scuteri A, deGroof RC, Lakatta EG. Improved arterial compliance by a novel advanced glycation end-product crosslink breaker. Circulation. 2001;104:1464-1470.
-
(2001)
Circulation.
, vol.104
, pp. 1464-1470
-
-
Kass, D.A.1
Shapiro, E.P.2
Kawaguchi, M.3
Capriotti, A.R.4
Scuteri, A.5
Degroof, R.C.6
Lakatta, E.G.7
-
124
-
-
79961098801
-
Effects of alagebrium, an advanced glycation endproduct breaker, on exercise tolerance and cardiac function in patients with chronic heart failure
-
BENEFICIAL investigators
-
Hartog JW, Willemsen S, Van Veldhuisen DJ, Posma JL, Van Wijk LM, Hummel YM, Hillege HL, Voors AA; BENEFICIAL investigators. Effects of alagebrium, an advanced glycation endproduct breaker, on exercise tolerance and cardiac function in patients with chronic heart failure. Eur J Heart Fail. 2011;13:899-908.
-
(2011)
Eur J Heart Fail.
, vol.13
, pp. 899-908
-
-
Hartog, J.W.1
Willemsen, S.2
Van Veldhuisen, D.J.3
Posma, J.L.4
Van Wijk, L.M.5
Hummel, Y.M.6
Hillege, H.L.7
Voors, A.A.8
-
125
-
-
66949114470
-
Relaxin and its role in the development and treatment of fibrosis
-
Bennett RG. Relaxin and its role in the development and treatment of fibrosis. Transl Res. 2009;154:1-6.
-
(2009)
Transl Res.
, vol.154
, pp. 1-6
-
-
Bennett, R.G.1
-
126
-
-
0033837983
-
Collagen studies in late pregnant relaxin null mice
-
Zhao L, Samuel CS, Tregear GW, Beck F, Wintour EM. Collagen studies in late pregnant relaxin null mice. Biol Reprod. 2000;63:697-703.
-
(2000)
Biol Reprod.
, vol.63
, pp. 697-703
-
-
Zhao, L.1
Samuel, C.S.2
Tregear, G.W.3
Beck, F.4
Wintour, E.M.5
-
127
-
-
4344606223
-
Relaxin modulates cardiac fibroblast proliferation, differentiation, and collagen production and reverses cardiac fibrosis in vivo
-
Samuel CS, Unemori EN, Mookerjee I, Bathgate RA, Layfield SL, Mak J, Tregear GW, Du XJ. Relaxin modulates cardiac fibroblast proliferation, differentiation, and collagen production and reverses cardiac fibrosis in vivo. Endocrinology. 2004;145:4125-4133.
-
(2004)
Endocrinology.
, vol.145
, pp. 4125-4133
-
-
Samuel, C.S.1
Unemori, E.N.2
Mookerjee, I.3
Bathgate, R.A.4
Layfield, S.L.5
Mak, J.6
Tregear, G.W.7
Du, X.J.8
-
128
-
-
23844466328
-
Effect of relaxin on myocardial ischemia injury induced by isoproterenol
-
Zhang J, Qi YF, Geng B, Pan CS, Zhao J, Chen L, Yang J, Chang JK, Tang CS. Effect of relaxin on myocardial ischemia injury induced by isoproterenol. Peptides. 2005;26:1632-1639.
-
(2005)
Peptides.
, vol.26
, pp. 1632-1639
-
-
Zhang, J.1
Qi, Y.F.2
Geng, B.3
Pan, C.S.4
Zhao, J.5
Chen, L.6
Yang, J.7
Chang, J.K.8
Tang, C.S.9
-
129
-
-
36549032746
-
Adenovirusmediated delivery of relaxin reverses cardiac fibrosis
-
Bathgate RA, Lekgabe ED, McGuane JT, Su Y, Pham T, Ferraro T, Layfield S, Hannan RD, Thomas WG, Samuel CS, Du XJ. Adenovirusmediated delivery of relaxin reverses cardiac fibrosis. Mol Cell Endocrinol. 2008;280:30-38.
-
(2008)
Mol Cell Endocrinol.
, vol.280
, pp. 30-38
-
-
Bathgate, R.A.1
Lekgabe, E.D.2
McGuane, J.T.3
Su, Y.4
Pham, T.5
Ferraro, T.6
Layfield, S.7
Hannan, R.D.8
Thomas, W.G.9
Samuel, C.S.10
Du, X.J.11
-
130
-
-
84880771641
-
Relaxin suppresses atrial fibrillation by reversing fibrosis and myocyte hypertrophy and increasing conduction velocity and sodium current in spontaneously hypertensive rat hearts
-
Parikh A, Patel D, McTiernan CF, Xiang W, Haney J, Yang L, Lin B, Kaplan AD, Bett GC, Rasmusson RL, Shroff SG, Schwartzman D, Salama G. Relaxin suppresses atrial fibrillation by reversing fibrosis and myocyte hypertrophy and increasing conduction velocity and sodium current in spontaneously hypertensive rat hearts. Circ Res. 2013;113:313-321.
-
(2013)
Circ Res.
, vol.113
, pp. 313-321
-
-
Parikh, A.1
Patel, D.2
McTiernan, C.F.3
Xiang, W.4
Haney, J.5
Yang, L.6
Lin, B.7
Kaplan, A.D.8
Bett, G.C.9
Rasmusson, R.L.10
Shroff, S.G.11
Schwartzman, D.12
Salama, G.13
-
131
-
-
84871986523
-
Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): A randomised, placebo-controlled trial
-
RELAXin in Acute Heart Failure (RELAX-AHF) Investigators
-
Teerlink JR, Cotter G, Davison BA, et al; RELAXin in Acute Heart Failure (RELAX-AHF) Investigators. Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): A randomised, placebo-controlled trial. Lancet. 2013;381:29-39.
-
(2013)
Lancet.
, vol.381
, pp. 29-39
-
-
Teerlink, J.R.1
Cotter, G.2
Davison, B.A.3
-
132
-
-
65249109216
-
Recombinant human relaxin in the treatment of systemic sclerosis with diffuse cutaneous involvement: A randomized, double-blind, placebo-controlled trial
-
Relaxin Investigators and the Scleroderma Clinical Trials Consortium
-
Khanna D, Clements PJ, Furst DE, et al; Relaxin Investigators and the Scleroderma Clinical Trials Consortium. Recombinant human relaxin in the treatment of systemic sclerosis with diffuse cutaneous involvement: A randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 2009;60:1102-1111.
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 1102-1111
-
-
Khanna, D.1
Clements, P.J.2
Furst, D.E.3
-
133
-
-
33645493621
-
The architecture of the heart: Myocyte organization and the cardiac extracellular matrix
-
In Villarreal F, ed New York: Springer.
-
LeGrice I, Pope A, Smaill B. The architecture of the heart: Myocyte organization and the cardiac extracellular matrix. In: Villarreal F, ed. Interstitial fibrosis in heart failure. New York: Springer. 2005;3-21.
-
(2005)
Interstitial Fibrosis in Heart Failure
, pp. 3-21
-
-
Legrice, I.1
Pope, A.2
Smaill, B.3
|