Neutral endopeptidase inhibition and the natriuretic peptide system: An evolving strategy in cardiovascular therapeutics

European Heart Journal

Volumn 34, Issue 12, 2013, Pages 886-893

  Mangiafico, Sarah ^a   Costello Boerrigter, Lisa C ^a   Andersen, Ingrid A ^a   Cataliotti, Alessandro ^a   Burnett, John C ^a  

^a MAYO CLINIC   (United States)

Author keywords

Evolving strategy in cardiovascular therapeutics; Natriuretic peptide system; Neutral endopeptidase inhibition

Indexed keywords

3 (1 BIPHENYL 4 YLMETHYL 3 ETHOXYCARBONYL 1 BUTYLCARBAMOYL)PROPIONIC ACID; 3 (1 BIPHENYL 4 YLMETHYL 3 ETHOXYCARBONYL 1 BUTYLCARBAMOYL)PROPIONIC ACID PLUS VALSARTAN; ANGIOTENSIN RECEPTOR ANTAGONIST; ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; CANDOXATRIL; CANDOXATRILAT; CENDERITIDE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; LISINOPRIL; MEMBRANE METALLOENDOPEPTIDASE; NATRIURETIC FACTOR; NATRIURETIC PEPTIDE TYPE C; NESIRITIDE; OMAPATRILAT; VALSARTAN;

ANGIONEUROTIC EDEMA; ANTIHYPERTENSIVE THERAPY; ANTIPROLIFERATIVE ACTIVITY; CARDIOVASCULAR DISEASE; DRUG DOSE TITRATION; DRUG SAFETY; DRUG TOLERABILITY; ENDOTHELIUM CELL; ENZYMATIC DEGRADATION; ENZYME INHIBITION; ESSENTIAL HYPERTENSION; GENE DELIVERY SYSTEM; HEART EJECTION FRACTION; HEART FAILURE; HEART MUSCLE CELL; HUMAN; HYDROLYSIS; HYPERTENSION; KIDNEY VASCULAR RESISTANCE; LIPID OXIDATION; LOW DRUG DOSE; METABOLIC DISORDER; METABOLIC REGULATION; MISSENSE MUTATION; NATRIURESIS; NONHUMAN; OBESITY; OXYGEN CONSUMPTION; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; PROTEIN DEGRADATION; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; VASODILATATION;

ANGIOTENSIN RECEPTOR ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CARDIOVASCULAR DISEASES; DRUG THERAPY, COMBINATION; ENZYME INHIBITORS; HUMANS; NATRIURETIC PEPTIDES; NEPRILYSIN; PYRIDINES; SNAKE VENOMS; THIAZEPINES;

EID: 84875580118     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehs262     Document Type: Review

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