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Volumn 21, Issue 6, 2013, Pages 296-313

Allostatic load as a tool for monitoring physiological dysregulations and comorbidities in patients with severe mental Illnesses

Author keywords

Allostatic load; Bipolar disorder; Chronic stress; Comorbidities; Pharmacological allostatic load; Schizophrenia; Severe mental illness

Indexed keywords

BIOLOGICAL MARKER; PSYCHOTROPIC AGENT;

EID: 84896741081     PISSN: 10673229     EISSN: 14657309     Source Type: Journal    
DOI: 10.1097/HRP.0000000000000012     Document Type: Review
Times cited : (54)

References (210)
  • 1
    • 0035930175 scopus 로고    scopus 로고
    • From the World Health Organization. Mental health: New understanding, new hope
    • Brundtland GH. From the World Health Organization. Mental health: new understanding, new hope. JAMA 2001; 286:2391.
    • (2001) JAMA , vol.286 , pp. 2391
    • Brundtland, G.H.1
  • 2
    • 70349217937 scopus 로고    scopus 로고
    • Cardiovascular disease and diabetes in people with severe mental illness: Position statement from the European Psychiatric Association (EPA), supported by the European Association for the Study of Diabetes (EASD) and the European Society of Cardiology (ESC)
    • De Hert M, Dekker JM, Wood D, Kahl KG, Holt RI, Moller HJ. Cardiovascular disease and diabetes in people with severe mental illness: position statement from the European Psychiatric Association (EPA), supported by the European Association for the Study of Diabetes (EASD) and the European Society of Cardiology (ESC). Eur Psychiatry 2009;24: 412-24.
    • (2009) Eur Psychiatry , vol.24 , pp. 412-424
    • De Hert, M.1    Dekker, J.M.2    Wood, D.3    Kahl, K.G.4    Holt, R.I.5    Moller, H.J.6
  • 3
    • 34948840329 scopus 로고    scopus 로고
    • A systematic review of mortality in schizophrenia: Is the differential mortality gap worsening over time?
    • Saha S, Chant D, McGrath J. A systematic review of mortality in schizophrenia: is the differential mortality gap worsening over time? Arch Gen Psychiatry 2007;64:1123-31.
    • (2007) Arch Gen Psychiatry , vol.64 , pp. 1123-1131
    • Saha, S.1    Chant, D.2    McGrath, J.3
  • 4
    • 0036280163 scopus 로고    scopus 로고
    • Mortality of patients with mood disorders: Follow-up over 34-38 years
    • Angst F, Stassen HH, Clayton PJ, Angst J. Mortality of patients with mood disorders: follow-up over 34-38 years. J Affect Disord 2002;68:167-81.
    • (2002) J Affect Disord , vol.68 , pp. 167-181
    • Angst, F.1    Stassen, H.H.2    Clayton, P.J.3    Angst, J.4
  • 5
    • 0030799116 scopus 로고    scopus 로고
    • Price of adaptation - Allostatic load and its health consequences. MacArthur studies of successful aging
    • Seeman TE, Singer BH, Rowe JW, Horwitz RI, McEwen BS. Price of adaptation - allostatic load and its health consequences. MacArthur studies of successful aging. Arch Intern Med 1997;157:2259-68.
    • (1997) Arch Intern Med , vol.157 , pp. 2259-2268
    • Seeman, T.E.1    Singer, B.H.2    Rowe, J.W.3    Horwitz, R.I.4    McEwen, B.S.5
  • 6
    • 84866640082 scopus 로고    scopus 로고
    • A systematic review of allostatic load, health, and health disparities
    • Beckie TM. A systematic review of allostatic load, health, and health disparities. Biol Res Nurs 2012;14:311-46.
    • (2012) Biol Res Nurs , vol.14 , pp. 311-346
    • Beckie, T.M.1
  • 7
    • 77955919761 scopus 로고    scopus 로고
    • Allostatic load biomarkers of chronic stress and impacton health and cognition
    • Juster RP, McEwen BS, Lupien SJ. Allostatic load biomarkers of chronic stress and impacton health and cognition. Neurosci Biobehav Rev 2010;35:2-16.
    • (2010) Neurosci Biobehav Rev , vol.35 , pp. 2-16
    • Juster, R.P.1    McEwen, B.S.2    Lupien, S.J.3
  • 8
    • 40149096962 scopus 로고    scopus 로고
    • Allostatic load in bipolar disorder: Implications for pathophysiology and treatment
    • Kapczinski F, Vieta E, Andreazza AC, et al. Allostatic load in bipolar disorder: implications for pathophysiology and treatment. Neurosci Biobehav Rev 2008;32:675-92.
    • (2008) Neurosci Biobehav Rev , vol.32 , pp. 675-692
    • Kapczinski, F.1    Vieta, E.2    Andreazza, A.C.3
  • 9
    • 0000310973 scopus 로고
    • Allostasis: A new paradigm to explain arousal pathology
    • Fisher S, Reason J, eds. New York: Wiley
    • Sterling P, Eyer J. Allostasis: a new paradigm to explain arousal pathology. In: Fisher S, Reason J, eds. Handbook of life stress, cognition and health. New York: Wiley, 1988:629-49.
    • (1988) Handbook of Life Stress, Cognition and Health , pp. 629-649
    • Sterling, P.1    Eyer, J.2
  • 10
    • 84954243686 scopus 로고    scopus 로고
    • Principles of allostasis: Optimal design, predictive regulation, pathophysiology and rational therapeutics
    • Schulkin J, ed. Cambridge: Cambridge University Press
    • Sterling P. Principles of allostasis: optimal design, predictive regulation, pathophysiology and rational therapeutics. In: Schulkin J, ed. Allostasis, homeostasis, and the costs of adaptation. Cambridge: Cambridge University Press, 2004:17-64.
    • (2004) Allostasis, Homeostasis, and the Costs of Adaptation , pp. 17-64
    • Sterling, P.1
  • 11
    • 0037220421 scopus 로고    scopus 로고
    • Allostasis: A neural behavioral perspective
    • discussion 8-30
    • Schulkin J. Allostasis: a neural behavioral perspective. Horm Behav 2003;43:21-7; discussion 8-30.
    • (2003) Horm Behav , vol.43 , pp. 21-27
    • Schulkin, J.1
  • 12
    • 0034454682 scopus 로고    scopus 로고
    • How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions
    • Sapolsky RM, Romero LM, Munck AU. How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions. Endocr Rev 2000;21:55-89.
    • (2000) Endocr Rev , vol.21 , pp. 55-89
    • Sapolsky, R.M.1    Romero, L.M.2    Munck, A.U.3
  • 13
    • 0032078238 scopus 로고    scopus 로고
    • Stress, adaptation, and disease. Allostasis and allostatic load
    • McEwen BS. Stress, adaptation, and disease. Allostasis and allostatic load. Ann N Y Acad Sci 1998;840:33-44.
    • (1998) Ann N y Acad Sci , vol.840 , pp. 33-44
    • McEwen, B.S.1
  • 14
    • 0027515623 scopus 로고
    • Stress and the individual. Mechanisms leading to disease
    • McEwen BS, Stellar E. Stress and the individual. Mechanisms leading to disease. Arch Intern Med 1993;153:2093-101.
    • (1993) Arch Intern Med , vol.153 , pp. 2093-2101
    • McEwen, B.S.1    Stellar, E.2
  • 15
    • 0034142298 scopus 로고    scopus 로고
    • Allostasis and allostatic load: Implications for neuropsychopharmacology
    • McEwen BS. Allostasis and allostatic load: implications for neuropsychopharmacology. Neuropsychopharmacology 2000;22:108-24.
    • (2000) Neuropsychopharmacology , vol.22 , pp. 108-124
    • McEwen, B.S.1
  • 16
    • 84870495336 scopus 로고    scopus 로고
    • Chronic stress and allostatic load
    • Schenck-Gustafsson K, DeCola PR, Pfaff DW, Pisetsky DS, eds. Basel: Karger
    • Juster RP, Lupien SJ. Chronic stress and allostatic load. In: Schenck-Gustafsson K, DeCola PR, Pfaff DW, Pisetsky DS, eds. Handbook of clinical gender medicine. Basel: Karger, 2012:70-81.
    • (2012) Handbook of Clinical Gender Medicine , pp. 70-81
    • Juster, R.P.1    Lupien, S.J.2
  • 18
    • 42049117789 scopus 로고    scopus 로고
    • Diverse pathways to positive and negative affect in adulthood and later life: An integrative approach using recursive partitioning
    • Gruenewald TL, Mroczek DK, Ryff CD, Singer BH. Diverse pathways to positive and negative affect in adulthood and later life: an integrative approach using recursive partitioning. Dev Psychol 2008;44:330-43.
    • (2008) Dev Psychol , vol.44 , pp. 330-343
    • Gruenewald, T.L.1    Mroczek, D.K.2    Ryff, C.D.3    Singer, B.H.4
  • 19
    • 0035836692 scopus 로고    scopus 로고
    • Allostatic load as a marker of cumulative biological risk: MacArthur studies of successful aging
    • Seeman TE, McEwen BS, Rowe JW, Singer BH. Allostatic load as a marker of cumulative biological risk: MacArthur studies of successful aging. Proc Natl Acad Sci U S A 2001;98: 4770-5.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 4770-4775
    • Seeman, T.E.1    McEwen, B.S.2    Rowe, J.W.3    Singer, B.H.4
  • 20
    • 33750075775 scopus 로고    scopus 로고
    • Physiological dysregulation and changes in health in an older population
    • Goldman N, Turra CM, Glei DA, Lin YH, Weinstein M. Physiological dysregulation and changes in health in an older population. Exp Gerontol 2006;41:862-70.
    • (2006) Exp Gerontol , vol.41 , pp. 862-870
    • Goldman, N.1    Turra, C.M.2    Glei, D.A.3    Lin, Y.H.4    Weinstein, M.5
  • 22
    • 20144377464 scopus 로고    scopus 로고
    • A comparative analysis of measurement approaches for physiological dysregulation in an older population
    • Seplaki CL, Goldman N, Glei D, Weinstein M. A comparative analysis of measurement approaches for physiological dysregulation in an older population. Exp Gerontol 2005;40:438-49.
    • (2005) Exp Gerontol , vol.40 , pp. 438-449
    • Seplaki, C.L.1    Goldman, N.2    Glei, D.3    Weinstein, M.4
  • 23
    • 1642275619 scopus 로고    scopus 로고
    • How are biomarkers related to physical and mental well-being?
    • Seplaki CL, Goldman N, Weinstein M, Lin YH. How are biomarkers related to physical and mental well-being? J Gerentol 2004;59A:201-17.
    • (2004) J Gerentol , vol.59 , Issue.A , pp. 201-217
    • Seplaki, C.L.1    Goldman, N.2    Weinstein, M.3    Lin, Y.H.4
  • 24
    • 33646793648 scopus 로고    scopus 로고
    • Measurement of cumulative physiological dysregulation in an older population
    • Seplaki CL, Goldman N, Weinstein M, Lin YH. Measurement of cumulative physiological dysregulation in an older population. Demography 2006;43:165-83.
    • (2006) Demography , vol.43 , pp. 165-183
    • Seplaki, C.L.1    Goldman, N.2    Weinstein, M.3    Lin, Y.H.4
  • 25
    • 33746099750 scopus 로고    scopus 로고
    • Reduction in allostatic load in older adults is associated with lower allcause mortality risk: MacArthur studies of successful aging
    • Karlamangla AS, Singer BH, Seeman TE. Reduction in allostatic load in older adults is associated with lower allcause mortality risk: MacArthur studies of successful aging. Psychosom Med 2006;68:500-7.
    • (2006) Psychosom Med , vol.68 , pp. 500-507
    • Karlamangla, A.S.1    Singer, B.H.2    Seeman, T.E.3
  • 26
    • 44849100969 scopus 로고    scopus 로고
    • Comorbid somatic illnesses in patients with severe mental disorders: Clinical, policy, and research challenges
    • Fleischhacker WW, Cetkovich-Bakmas M, De Hert M, et al. Comorbid somatic illnesses in patients with severe mental disorders: clinical, policy, and research challenges. J Clin Psychiatry 2008;69:514-9.
    • (2008) J Clin Psychiatry , vol.69 , pp. 514-519
    • Fleischhacker, W.W.1    Cetkovich-Bakmas, M.2    De Hert, M.3
  • 27
    • 0030694189 scopus 로고    scopus 로고
    • Excess mortality of schizophrenia: A meta-analysis
    • Brown S. Excess mortality of schizophrenia: a meta-analysis. Br J Psychiatry 1997;171:502-8.
    • (1997) Br J Psychiatry , vol.171 , pp. 502-508
    • Brown, S.1
  • 28
    • 33748561486 scopus 로고    scopus 로고
    • Medical risk in patients with bipolar disorder and schizophrenia
    • discussion 36-42
    • Newcomer JW. Medical risk in patients with bipolar disorder and schizophrenia. J Clin Psychiatry 2006;67 suppl 9:25-30; discussion 36-42.
    • (2006) J Clin Psychiatry , vol.67 , Issue.SUPPL. 9 , pp. 25-30
    • Newcomer, J.W.1
  • 29
    • 0034686911 scopus 로고    scopus 로고
    • Time trends in schizophrenia mortality in Stockholm county, Sweden: Cohort study
    • Osby U, Correia N, Brandt L, Ekbom A, Sparen P. Time trends in schizophrenia mortality in Stockholm county, Sweden: cohort study. BMJ 2000;321:483-4.
    • (2000) BMJ , vol.321 , pp. 483-484
    • Osby, U.1    Correia, N.2    Brandt, L.3    Ekbom, A.4    Sparen, P.5
  • 30
    • 28844485754 scopus 로고    scopus 로고
    • Schizophrenia and increased risks of cardiovascular disease
    • Hennekens CH, Hennekens AR, Hollar D, Casey DE. Schizophrenia and increased risks of cardiovascular disease. Am Heart J 2005;150:1115-21.
    • (2005) Am Heart J , vol.150 , pp. 1115-1121
    • Hennekens, C.H.1    Hennekens, A.R.2    Hollar, D.3    Casey, D.E.4
  • 31
    • 33744913823 scopus 로고    scopus 로고
    • Diabetes and schizophrenia 2005: Are we any closer to understanding the link?
    • Holt RI, Bushe C, Citrome L. Diabetes and schizophrenia 2005: are we any closer to understanding the link? J Psychopharmacol 2005;19:56-65.
    • (2005) J Psychopharmacol , vol.19 , pp. 56-65
    • Holt, R.I.1    Bushe, C.2    Citrome, L.3
  • 32
    • 22044436909 scopus 로고    scopus 로고
    • Bipolar disorder and diabetes mellitus: Epidemiology, etiology, and treatment implications
    • McIntyre RS, Konarski JZ, Misener VL, Kennedy SH. Bipolar disorder and diabetes mellitus: epidemiology, etiology, and treatment implications. Ann Clin Psychiatry 2005;17:83-93.
    • (2005) Ann Clin Psychiatry , vol.17 , pp. 83-93
    • McIntyre, R.S.1    Konarski, J.Z.2    Misener, V.L.3    Kennedy, S.H.4
  • 33
    • 0242302508 scopus 로고    scopus 로고
    • Interacting mediators of allostasis and allostatic load: Towards an understanding of resilience in aging
    • McEwen BS. Interacting mediators of allostasis and allostatic load: towards an understanding of resilience in aging. Metabolism 2003;52:10-6.
    • (2003) Metabolism , vol.52 , pp. 10-16
    • McEwen, B.S.1
  • 34
    • 0032518022 scopus 로고    scopus 로고
    • Protective and damaging effects of stress mediators
    • McEwen BS. Protective and damaging effects of stress mediators. N Engl J Med 1998;338:171-9.
    • (1998) N Engl J Med , vol.338 , pp. 171-179
    • McEwen, B.S.1
  • 35
    • 3543112049 scopus 로고    scopus 로고
    • Platelet serotonin and plasma prolactin and cortisol in healthy, depressed and schizophrenic women
    • Muck-Seler D, Pivac N, Mustapic M, Crncevic Z, Jakovljevic M, Sagud M. Platelet serotonin and plasma prolactin and cortisol in healthy, depressed and schizophrenic women. Psychiatry Res 2004;127:217-26.
    • (2004) Psychiatry Res , vol.127 , pp. 217-226
    • Muck-Seler, D.1    Pivac, N.2    Mustapic, M.3    Crncevic, Z.4    Jakovljevic, M.5    Sagud, M.6
  • 36
    • 13844271916 scopus 로고    scopus 로고
    • Male patients with paranoid schizophrenia have greater ACTH and cortisol secretion in response to metoclopramide-induced AVP release
    • Walsh P, Spelman L, Sharifi N, Thakore JH. Male patients with paranoid schizophrenia have greater ACTH and cortisol secretion in response to metoclopramide-induced AVP release. Psychoneuroendocrinology 2005;30:431-7.
    • (2005) Psychoneuroendocrinology , vol.30 , pp. 431-437
    • Walsh, P.1    Spelman, L.2    Sharifi, N.3    Thakore, J.H.4
  • 37
    • 33846643951 scopus 로고    scopus 로고
    • Plasma cortisol-dehydroepiandrosterone (DHEA) ratios in schizophrenia and bipolar disorder
    • Gallagher P, Watson S, Smith MS, Young AH, Ferrier IN. Plasma cortisol-dehydroepiandrosterone (DHEA) ratios in schizophrenia and bipolar disorder. Schizophr Res 2007;90: 258-65.
    • (2007) Schizophr Res , vol.90 , pp. 258-265
    • Gallagher, P.1    Watson, S.2    Smith, M.S.3    Young, A.H.4    Ferrier, I.N.5
  • 38
    • 33846402115 scopus 로고    scopus 로고
    • State and trait related predictors of serum cortisol to DHEA(S) molar ratios and hormone concentrations in schizophrenia patients
    • Ritsner M, Gibel A, Maayan R, et al. State and trait related predictors of serum cortisol to DHEA(S) molar ratios and hormone concentrations in schizophrenia patients. Eur Neuropsychopharmacol 2007;17:257-64.
    • (2007) Eur Neuropsychopharmacol , vol.17 , pp. 257-264
    • Ritsner, M.1    Gibel, A.2    Maayan, R.3
  • 39
    • 33847058371 scopus 로고    scopus 로고
    • Increased levels of nitric oxide, cortisol and adrenomedullin in patients with chronic schizophrenia
    • Yilmaz N, Herken H, Cicek HK, Celik A, Yurekli M, Akyol O. Increased levels of nitric oxide, cortisol and adrenomedullin in patients with chronic schizophrenia. Med Princ Pract 2007;16:137-41.
    • (2007) Med Princ Pract , vol.16 , pp. 137-141
    • Yilmaz, N.1    Herken, H.2    Cicek, H.K.3    Celik, A.4    Yurekli, M.5    Akyol, O.6
  • 40
    • 0027959021 scopus 로고
    • The 24-hour profiles of cortisol, prolactin, and growth hormone secretion in mania
    • Linkowski P, Kerkhofs M, Van Onderbergen A, et al. The 24-hour profiles of cortisol, prolactin, and growth hormone secretion in mania. Arch Gen Psychiatry 1994;51:616-24.
    • (1994) Arch Gen Psychiatry , vol.51 , pp. 616-624
    • Linkowski, P.1    Kerkhofs, M.2    Van Onderbergen, A.3
  • 41
    • 0345466578 scopus 로고    scopus 로고
    • Platelet serotonin, plasma cortisol, and dexamethasone suppression test in schizophrenic patients
    • Muck-Seler D, Pivac N, Jakovljevic M, Brzovic Z. Platelet serotonin, plasma cortisol, and dexamethasone suppression test in schizophrenic patients. Biol Psychiatry 1999;45:1433-9.
    • (1999) Biol Psychiatry , vol.45 , pp. 1433-1439
    • Muck-Seler, D.1    Pivac, N.2    Jakovljevic, M.3    Brzovic, Z.4
  • 43
    • 33750797822 scopus 로고    scopus 로고
    • Combined dexamethasone suppression-corticotropin-releasing hormone stimulation test in studies of depression, alcoholism, and suicidal behavior
    • Sher L. Combined dexamethasone suppression-corticotropin-releasing hormone stimulation test in studies of depression, alcoholism, and suicidal behavior. ScientificWorldJournal 2006;6:1398-404.
    • (2006) ScientificWorldJournal , vol.6 , pp. 1398-1404
    • Sher, L.1
  • 45
    • 0030889592 scopus 로고    scopus 로고
    • Prediction of depressive relapse in remitted bipolar patients using corticotrophin-releasing hormone challenge test
    • Vieta E, Gasto C, Martinez de Osaba MJ, et al. Prediction of depressive relapse in remitted bipolar patients using corticotrophin-releasing hormone challenge test. Acta Psychiatr Scand 1997;95:205-11.
    • (1997) Acta Psychiatr Scand , vol.95 , pp. 205-211
    • Vieta, E.1    Gasto, C.2    Martinez De Osaba, M.J.3
  • 46
    • 58049137940 scopus 로고    scopus 로고
    • Neurobiological and neuropsychiatric effects of dehydroepi-androsterone (DHEA) and DHEA sulfate (DHEAS)
    • Maninger N, Wolkowitz OM, Reus VI, Epel ES, Mellon SH. Neurobiological and neuropsychiatric effects of dehydroepi-androsterone (DHEA) and DHEA sulfate (DHEAS). Front Neuroendocrinol 2009;30:65-91.
    • (2009) Front Neuroendocrinol , vol.30 , pp. 65-91
    • Maninger, N.1    Wolkowitz, O.M.2    Reus, V.I.3    Epel, E.S.4    Mellon, S.H.5
  • 47
    • 40949107708 scopus 로고    scopus 로고
    • Inflammatory cytokine alterations in schizophrenia: A systematic quantitative review
    • Potvin S, Stip E, Sepehry AA, Gendron A, Bah R, Kouassi E. Inflammatory cytokine alterations in schizophrenia: a systematic quantitative review. Biol Psychiatry 2008;63: 801-8.
    • (2008) Biol Psychiatry , vol.63 , pp. 801-808
    • Potvin, S.1    Stip, E.2    Sepehry, A.A.3    Gendron, A.4    Bah, R.5    Kouassi, E.6
  • 48
    • 12244286806 scopus 로고    scopus 로고
    • High numbers of circulating activated T cells and raised levels of serum IL-2 receptor in bipolar disorder
    • Breunis MN, Kupka RW, Nolen WA, et al. High numbers of circulating activated T cells and raised levels of serum IL-2 receptor in bipolar disorder. Biol Psychiatry 2003;53:157-65.
    • (2003) Biol Psychiatry , vol.53 , pp. 157-165
    • Breunis, M.N.1    Kupka, R.W.2    Nolen, W.A.3
  • 49
    • 35948958993 scopus 로고    scopus 로고
    • Imbalance between pro-inflammatory and anti-inflammatory cytokines in bipolar disorder
    • Kim YK, Jung HG, Myint AM, Kim H, Park SH. Imbalance between pro-inflammatory and anti-inflammatory cytokines in bipolar disorder. J Affect Disord 2007;104:91-5.
    • (2007) J Affect Disord , vol.104 , pp. 91-95
    • Kim, Y.K.1    Jung, H.G.2    Myint, A.M.3    Kim, H.4    Park, S.H.5
  • 51
    • 31844457040 scopus 로고    scopus 로고
    • Cytokine profiles in bipolar affective disorder: Focus on acutely ill patients
    • O'Brien SM, Scully P, Scott LV, Dinan TG. Cytokine profiles in bipolar affective disorder: focus on acutely ill patients. J Affect Disord 2006;90:263-7.
    • (2006) J Affect Disord , vol.90 , pp. 263-267
    • O'Brien, S.M.1    Scully, P.2    Scott, L.V.3    Dinan, T.G.4
  • 52
    • 34548412812 scopus 로고    scopus 로고
    • Immune variations in bipolar disorder: Phasic differences
    • Ortiz-Dominguez A, Hernandez ME, Berlanga C, et al. Immune variations in bipolar disorder: phasic differences. Bipolar Disord 2007;9:596-602.
    • (2007) Bipolar Disord , vol.9 , pp. 596-602
    • Ortiz-Dominguez, A.1    Hernandez, M.E.2    Berlanga, C.3
  • 53
    • 0033560674 scopus 로고    scopus 로고
    • Activation of indices of cell-mediated immunity in bipolar mania
    • Tsai SY, Chen KP, Yang YY, et al. Activation of indices of cell-mediated immunity in bipolar mania. Biol Psychiatry 1999;45:989-94.
    • (1999) Biol Psychiatry , vol.45 , pp. 989-994
    • Tsai, S.Y.1    Chen, K.P.2    Yang, Y.Y.3
  • 54
    • 6944237757 scopus 로고    scopus 로고
    • Adipokines: Inflammation and the pleiotropic role of white adipose tissue
    • Trayhurn P, Wood IS. Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br J Nutr 2004;92: 347-55.
    • (2004) Br J Nutr , vol.92 , pp. 347-355
    • Trayhurn, P.1    Wood, I.S.2
  • 55
    • 71649115889 scopus 로고    scopus 로고
    • Depression, traumatic stress and interleukin-6
    • Bob P, Raboch J, Maes M, et al. Depression, traumatic stress and interleukin-6. J Affect Disord 2010;120:231-4.
    • (2010) J Affect Disord , vol.120 , pp. 231-234
    • Bob, P.1    Raboch, J.2    Maes, M.3
  • 56
    • 68749094080 scopus 로고    scopus 로고
    • Cardiovascular disease and hypertension among adults with bipolar I disorder in the United States
    • Goldstein BI, Fagiolini A, Houck P, Kupfer DJ. Cardiovascular disease and hypertension among adults with bipolar I disorder in the United States. Bipolar Disord 2009;11:657-62.
    • (2009) Bipolar Disord , vol.11 , pp. 657-662
    • Goldstein, B.I.1    Fagiolini, A.2    Houck, P.3    Kupfer, D.J.4
  • 57
    • 60349126636 scopus 로고    scopus 로고
    • A prospective observational study of obesity, body composition, and insulin resistance in 18 women with bipolar disorder and 17 matched control subjects
    • Fleet-Michaliszyn SB, Soreca I, Otto AD, et al. A prospective observational study of obesity, body composition, and insulin resistance in 18 women with bipolar disorder and 17 matched control subjects. J Clin Psychiatry 2008;69:1892-900.
    • (2008) J Clin Psychiatry , vol.69 , pp. 1892-1900
    • Fleet-Michaliszyn, S.B.1    Soreca, I.2    Otto, A.D.3
  • 59
    • 34247158550 scopus 로고    scopus 로고
    • Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases
    • Trushina E, McMurray CT. Oxidative stress and mitochondrial dysfunction in neurodegenerative diseases. Neuroscience 2007; 145:1233-48.
    • (2007) Neuroscience , vol.145 , pp. 1233-1248
    • Trushina, E.1    McMurray, C.T.2
  • 60
    • 80054925531 scopus 로고    scopus 로고
    • A transdisciplinary perspective of chronic stress in relation to psychopathology throughout life span development
    • Juster RP, Bizik G, Picard M, et al. A transdisciplinary perspective of chronic stress in relation to psychopathology throughout life span development. Dev Psychopathol 2011; 23:725-76.
    • (2011) Dev Psychopathol , vol.23 , pp. 725-776
    • Juster, R.P.1    Bizik, G.2    Picard, M.3
  • 61
    • 84862591992 scopus 로고    scopus 로고
    • Illness comorbidity as a biomarker?
    • Anisman H, Hayley S. Illness comorbidity as a biomarker? J Psychiatry Neurosci 2012;37:221-3.
    • (2012) J Psychiatry Neurosci , vol.37 , pp. 221-223
    • Anisman, H.1    Hayley, S.2
  • 63
    • 12744278045 scopus 로고    scopus 로고
    • Psychiatric and medical comorbidities of bipolar disorder
    • Krishnan KR. Psychiatric and medical comorbidities of bipolar disorder. Psychosom Med 2005;67:1-8.
    • (2005) Psychosom Med , vol.67 , pp. 1-8
    • Krishnan, K.R.1
  • 64
    • 0035096665 scopus 로고    scopus 로고
    • Axis I psychiatric comorbidity and its relationship to historical illness variables in 288 patients with bipolar disorder
    • McElroy SL, Altshuler LL, Suppes T, et al. Axis I psychiatric comorbidity and its relationship to historical illness variables in 288 patients with bipolar disorder. Am J Psychiatry 2001; 158:420-6.
    • (2001) Am J Psychiatry , vol.158 , pp. 420-426
    • McElroy, S.L.1    Altshuler, L.L.2    Suppes, T.3
  • 65
    • 0025226205 scopus 로고
    • Comorbidity of mental disorders with alcohol and other drug abuse. Results from the Epidemiologic Catchment Area (ECA) Study
    • Regier DA, Farmer ME, Rae DS, et al. Comorbidity of mental disorders with alcohol and other drug abuse. Results from the Epidemiologic Catchment Area (ECA) Study. JAMA 1990; 264:2511-8.
    • (1990) JAMA , vol.264 , pp. 2511-2518
    • Regier, D.A.1    Farmer, M.E.2    Rae, D.S.3
  • 66
    • 84857122622 scopus 로고    scopus 로고
    • Allostasis and addiction: Role of the dopamine and corticotropin- releasing factor systems
    • George O, Le Moal M, Koob GF. Allostasis and addiction: role of the dopamine and corticotropin-releasing factor systems. Physiol Behav 2012;106:58-64.
    • (2012) Physiol Behav , vol.106 , pp. 58-64
    • George, O.1    Le Moal, M.2    Koob, G.F.3
  • 67
    • 0037329682 scopus 로고    scopus 로고
    • Alcoholism: Allostasis and beyond
    • Koob GF. Alcoholism: allostasis and beyond. Alcohol Clin Exp Res 2003;27:232-43.
    • (2003) Alcohol Clin Exp Res , vol.27 , pp. 232-243
    • Koob, G.F.1
  • 68
    • 1042266422 scopus 로고    scopus 로고
    • Neurobiological mechanisms in the transition from drug use to drug dependence
    • Koob GF, Ahmed SH, Boutrel B, et al. Neurobiological mechanisms in the transition from drug use to drug dependence. Neurosci Biobehav Rev 2004;27:739-49.
    • (2004) Neurosci Biobehav Rev , vol.27 , pp. 739-749
    • Koob, G.F.1    Ahmed, S.H.2    Boutrel, B.3
  • 69
    • 0035199891 scopus 로고    scopus 로고
    • Drug addiction, dysregulation of reward, and allostasis
    • Koob GF, Le Moal M. Drug addiction, dysregulation of reward, and allostasis. Neuropsychopharmacology 2001;24: 97-129.
    • (2001) Neuropsychopharmacology , vol.24 , pp. 97-129
    • Koob, G.F.1    Le Moal, M.2
  • 71
    • 10044267876 scopus 로고    scopus 로고
    • Allostasis and dysregulation of corticotropin-releasing factor and neuropeptide Y systems: Implications for the development of alcoholism
    • Valdez GR, Koob GF. Allostasis and dysregulation of corticotropin- releasing factor and neuropeptide Y systems: implications for the development of alcoholism. Pharmacol Biochem Behav 2004;79:671-89.
    • (2004) Pharmacol Biochem Behav , vol.79 , pp. 671-689
    • Valdez, G.R.1    Koob, G.F.2
  • 73
    • 0141832631 scopus 로고    scopus 로고
    • Mood disorders and allostatic load
    • McEwen BS. Mood disorders and allostatic load. Biol Psychiatry 2003;54:200-7.
    • (2003) Biol Psychiatry , vol.54 , pp. 200-207
    • McEwen, B.S.1
  • 74
    • 17444413709 scopus 로고    scopus 로고
    • Glucocorticoids, depression, and mood disorders: Structural remodeling in the brain
    • McEwen BS. Glucocorticoids, depression, and mood disorders: structural remodeling in the brain. Metabolism 2005;54:20-3.
    • (2005) Metabolism , vol.54 , pp. 20-23
    • McEwen, B.S.1
  • 75
    • 14544269337 scopus 로고    scopus 로고
    • Protection and damage from acute and chronic stress: Allostasis and allostatic overload and relevance to the pathophysiology of psychiatric disorders
    • McEwen BS. Protection and damage from acute and chronic stress: allostasis and allostatic overload and relevance to the pathophysiology of psychiatric disorders. Ann N Y Acad Sci 2004;1032:1-7.
    • (2004) Ann N y Acad Sci , vol.1032 , pp. 1-7
    • McEwen, B.S.1
  • 76
    • 0031859325 scopus 로고    scopus 로고
    • Induction of corticotropin-releasing hormone gene expression by glucocorticoids: Implication for understanding the states of fear and anxiety and allostatic load
    • Schulkin J, Gold PW, McEwen BS. Induction of corticotropin-releasing hormone gene expression by glucocorticoids: implication for understanding the states of fear and anxiety and allostatic load. Psychoneuroendocrinology 1998;23: 219-43.
    • (1998) Psychoneuroendocrinology , vol.23 , pp. 219-243
    • Schulkin, J.1    Gold, P.W.2    McEwen, B.S.3
  • 78
    • 0036315254 scopus 로고    scopus 로고
    • The neurobiology and neuroendocrinology of stress. Implications for post-traumatic stress disorder from a basic science perspective
    • ix
    • McEwen BS. The neurobiology and neuroendocrinology of stress. Implications for post-traumatic stress disorder from a basic science perspective. Psychiatr Clin North Am 2002;25: 469-94, ix.
    • (2002) Psychiatr Clin North Am , vol.25 , pp. 469-494
    • McEwen, B.S.1
  • 80
    • 0242363786 scopus 로고    scopus 로고
    • Subsyndromal symptoms assessed in longitudinal, prospective follow-up of a cohort of patients with bipolar disorder
    • MacQueen GM, Marriott M, Begin H, Robb J, Joffe RT, Young LT. Subsyndromal symptoms assessed in longitudinal, prospective follow-up of a cohort of patients with bipolar disorder. Bipolar Disord 2003;5:349-55.
    • (2003) Bipolar Disord , vol.5 , pp. 349-355
    • MacQueen, G.M.1    Marriott, M.2    Begin, H.3    Robb, J.4    Joffe, R.T.5    Young, L.T.6
  • 81
    • 33748786233 scopus 로고    scopus 로고
    • Food intake and reward mechanisms in patients with schizophrenia: Implications for metabolic disturbances and treatment with second-generation antipsychotic agents
    • Elman I, Borsook D, Lukas SE. Food intake and reward mechanisms in patients with schizophrenia: implications for metabolic disturbances and treatment with second-generation antipsychotic agents. Neuropsychopharmacology 2006;31: 2091-120.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2091-2120
    • Elman, I.1    Borsook, D.2    Lukas, S.E.3
  • 82
    • 0141816736 scopus 로고    scopus 로고
    • Chronic stress and obesity: A new view of "comfort food"
    • Dallman MF, Pecoraro N, Akana SF, et al. Chronic stress and obesity: a new view of "comfort food." Proc Natl Acad Sci U S A 2003;100:11696-701.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 11696-701
    • Dallman, M.F.1    Pecoraro, N.2    Akana, S.F.3
  • 83
    • 84872388142 scopus 로고    scopus 로고
    • The clinical implications of cognitive impairment and allostatic load in bipolar disorder
    • Vieta E, Popovic D, Rosa AR, et al. The clinical implications of cognitive impairment and allostatic load in bipolar disorder. Eur Psychiatry 2013; 28:21-9.
    • (2013) Eur Psychiatry , vol.28 , pp. 21-29
    • Vieta, E.1    Popovic, D.2    Rosa, A.R.3
  • 85
    • 69249145260 scopus 로고    scopus 로고
    • Mechanisms underlying psychosis and antipsychotic treatment response in schizophrenia: Insights from PET and SPECT imaging
    • Howes OD, Egerton A, Allan V, McGuire P, Stokes P, Kapur S. Mechanisms underlying psychosis and antipsychotic treatment response in schizophrenia: insights from PET and SPECT imaging. Curr Pharm Des 2009;15:2550-9.
    • (2009) Curr Pharm Des , vol.15 , pp. 2550-2559
    • Howes, O.D.1    Egerton, A.2    Allan, V.3    McGuire, P.4    Stokes, P.5    Kapur, S.6
  • 86
    • 0037223711 scopus 로고    scopus 로고
    • Psychosis as a state of aberrant salience: A framework linking biology, phenomenology, and pharmacology in schizophrenia
    • Kapur S. Psychosis as a state of aberrant salience: a framework linking biology, phenomenology, and pharmacology in schizophrenia. Am J Psychiatry 2003;160:13-23.
    • (2003) Am J Psychiatry , vol.160 , pp. 13-23
    • Kapur, S.1
  • 87
    • 33244462829 scopus 로고    scopus 로고
    • How antipsychotics work - From receptors to reality
    • Kapur S, Agid O, Mizrahi R, Li M. How antipsychotics work - from receptors to reality. NeuroRx 2006;3:10-21.
    • (2006) NeuroRx , vol.3 , pp. 10-21
    • Kapur, S.1    Agid, O.2    Mizrahi, R.3    Li, M.4
  • 88
    • 0642309952 scopus 로고    scopus 로고
    • Emotions in unmedicated patients with schizophrenia during evaluation with positron emission tomography
    • Paradiso S, Andreasen NC, Crespo-Facorro B, et al. Emotions in unmedicated patients with schizophrenia during evaluation with positron emission tomography. Am J Psychiatry 2003; 160:1775-83.
    • (2003) Am J Psychiatry , vol.160 , pp. 1775-1783
    • Paradiso, S.1    Andreasen, N.C.2    Crespo-Facorro, B.3
  • 89
    • 0036897193 scopus 로고    scopus 로고
    • An fMRI study of facial emotion processing in patients with schizophrenia
    • Gur RE, McGrath C, Chan RM, et al. An fMRI study of facial emotion processing in patients with schizophrenia. Am J Psychiatry 2002;159:1992-9.
    • (2002) Am J Psychiatry , vol.159 , pp. 1992-1999
    • Gur, R.E.1    McGrath, C.2    Chan, R.M.3
  • 90
    • 0036512243 scopus 로고    scopus 로고
    • The effects of obesity, smoking, and drinking on medical problems and costs
    • Sturm R. The effects of obesity, smoking, and drinking on medical problems and costs. Health Aff (Millwood) 2002; 21:245-53.
    • (2002) Health Aff (Millwood) , vol.21 , pp. 245-253
    • Sturm, R.1
  • 91
    • 84878881481 scopus 로고    scopus 로고
    • Obesity and psychiatric disorders: Commonalities in dysregulated biological pathways and their implications for treatment
    • Lopresti AL, Drummond PD. Obesity and psychiatric disorders: commonalities in dysregulated biological pathways and their implications for treatment. Prog Neuropsychopharmacol Biol Psychiatry 2013;45:92-9.
    • (2013) Prog Neuropsychopharmacol Biol Psychiatry , vol.45 , pp. 92-99
    • Lopresti, A.L.1    Drummond, P.D.2
  • 92
    • 0032977072 scopus 로고    scopus 로고
    • The unhealthy lifestyle of people with schizophrenia
    • Brown S, Birtwistle J, Roe L, Thompson C. The unhealthy lifestyle of people with schizophrenia. Psychol Med 1999;29: 697-701.
    • (1999) Psychol Med , vol.29 , pp. 697-701
    • Brown, S.1    Birtwistle, J.2    Roe, L.3    Thompson, C.4
  • 93
    • 0141730334 scopus 로고    scopus 로고
    • Nutritional assessment of patients with schizophrenia: A preliminary study
    • Strassnig M, Brar JS, Ganguli R. Nutritional assessment of patients with schizophrenia: a preliminary study. Schizophr Bull 2003;29:393-7.
    • (2003) Schizophr Bull , vol.29 , pp. 393-397
    • Strassnig, M.1    Brar, J.S.2    Ganguli, R.3
  • 94
    • 0348014397 scopus 로고    scopus 로고
    • Diet, smoking and cardiovascular risk in people with schizophrenia: Descriptive study
    • McCreadie RG. Diet, smoking and cardiovascular risk in people with schizophrenia: descriptive study. Br J Psychiatry 2003;183:534-9.
    • (2003) Br J Psychiatry , vol.183 , pp. 534-539
    • McCreadie, R.G.1
  • 95
    • 1842784860 scopus 로고    scopus 로고
    • Diet, diabetes and schizophrenia: Review and hypothesis
    • Peet M. Diet, diabetes and schizophrenia: review and hypothesis. Br J Psychiatry Suppl 2004;47:S102-5.
    • (2004) Br J Psychiatry Suppl , vol.47
    • Peet, M.1
  • 96
    • 67650815430 scopus 로고    scopus 로고
    • Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans
    • Anderson EJ, Lustig ME, Boyle KE, et al. Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans. J Clin Invest 2009;119:573-81.
    • (2009) J Clin Invest , vol.119 , pp. 573-581
    • Anderson, E.J.1    Lustig, M.E.2    Boyle, K.E.3
  • 97
    • 23844558266 scopus 로고    scopus 로고
    • A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine
    • Wallace DC. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu Rev Genet 2005;39:359-407.
    • (2005) Annu Rev Genet , vol.39 , pp. 359-407
    • Wallace, D.C.1
  • 98
    • 0035878562 scopus 로고    scopus 로고
    • A neurobiological basis for substance abuse comorbidity in schizophrenia
    • Chambers RA, Krystal JH, Self DW. A neurobiological basis for substance abuse comorbidity in schizophrenia. Biol Psychiatry 2001;50:71-83.
    • (2001) Biol Psychiatry , vol.50 , pp. 71-83
    • Chambers, R.A.1    Krystal, J.H.2    Self, D.W.3
  • 99
    • 33947495416 scopus 로고    scopus 로고
    • The vulnerability to alcohol and substance abuse in individuals diagnosed with schizophrenia
    • Krystal JH, D'Souza DC, Gallinat J, et al. The vulnerability to alcohol and substance abuse in individuals diagnosed with schizophrenia. Neurotox Res 2006;10:235-52.
    • (2006) Neurotox Res , vol.10 , pp. 235-252
    • Krystal, J.H.1    D'Souza, D.C.2    Gallinat, J.3
  • 100
    • 34548084301 scopus 로고    scopus 로고
    • Enhanced nicotinic receptor function and drug abuse vulnerability
    • Fagen ZM, Mitchum R, Vezina P, McGehee DS. Enhanced nicotinic receptor function and drug abuse vulnerability. J Neurosci 2007;27:8771-8.
    • (2007) J Neurosci , vol.27 , pp. 8771-8778
    • Fagen, Z.M.1    Mitchum, R.2    Vezina, P.3    McGehee, D.S.4
  • 102
    • 0026495706 scopus 로고
    • Comorbidity of schizophrenia and substance abuse: Implications for treatment
    • Mueser KT, Bellack AS, Blanchard JJ. Comorbidity of schizophrenia and substance abuse: implications for treatment. J Consult Clin Psychol 1992;60:845-56.
    • (1992) J Consult Clin Psychol , vol.60 , pp. 845-856
    • Mueser, K.T.1    Bellack, A.S.2    Blanchard, J.J.3
  • 103
    • 54749129410 scopus 로고    scopus 로고
    • The molecular and cellular neurobiology of nicotine abuse in schizophrenia
    • Mobascher A, Winterer G. The molecular and cellular neurobiology of nicotine abuse in schizophrenia. Pharmacopsychiatry 2008;41 suppl 1:S51-9.
    • (2008) Pharmacopsychiatry , vol.41 , Issue.SUPPL. 1
    • Mobascher, A.1    Winterer, G.2
  • 104
    • 0029085870 scopus 로고
    • Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia
    • Freedman R, Hall M, Adler LE, Leonard S. Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia. Biol Psychiatry 1995;38:22-33.
    • (1995) Biol Psychiatry , vol.38 , pp. 22-33
    • Freedman, R.1    Hall, M.2    Adler, L.E.3    Leonard, S.4
  • 105
    • 32844461888 scopus 로고    scopus 로고
    • Nicotinic effects on cognitive function: Behavioral characterization, pharmacological specification, and anatomic localization
    • Levin ED, McClernon FJ, Rezvani AH. Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization. Psychopharmacology (Berl) 2006;184:523-39.
    • (2006) Psychopharmacology (Berl) , vol.184 , pp. 523-539
    • Levin, E.D.1    McClernon, F.J.2    Rezvani, A.H.3
  • 106
    • 0027380988 scopus 로고
    • Normalization of auditory physiology by cigarette smoking in schizophrenic patients
    • Adler LE, Hoffer LD, Wiser A, Freedman R. Normalization of auditory physiology by cigarette smoking in schizophrenic patients. Am J Psychiatry 1993;150:1856-61.
    • (1993) Am J Psychiatry , vol.150 , pp. 1856-1861
    • Adler, L.E.1    Hoffer, L.D.2    Wiser, A.3    Freedman, R.4
  • 107
    • 2942683373 scopus 로고    scopus 로고
    • Effects of nicotine on cognitive deficits in schizophrenia
    • Harris JG, Kongs S, Allensworth D, et al. Effects of nicotine on cognitive deficits in schizophrenia. Neuropsychopharmacology 2004;29:1378-85.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 1378-1385
    • Harris, J.G.1    Kongs, S.2    Allensworth, D.3
  • 108
    • 3843123190 scopus 로고    scopus 로고
    • Nicotine improves delayed recognition in schizophrenic patients
    • Myers CS, Robles O, Kakoyannis AN, et al. Nicotine improves delayed recognition in schizophrenic patients. Psychopharmacology (Berl) 2004;174:334-40.
    • (2004) Psychopharmacology (Berl) , vol.174 , pp. 334-340
    • Myers, C.S.1    Robles, O.2    Kakoyannis, A.N.3
  • 110
    • 0031470773 scopus 로고    scopus 로고
    • Nicotine activates and desensitizes midbrain dopamine neurons
    • Pidoplichko VI, DeBiasi M, Williams JT, Dani JA. Nicotine activates and desensitizes midbrain dopamine neurons. Nature 1997;390:401-4.
    • (1997) Nature , vol.390 , pp. 401-404
    • Pidoplichko, V.I.1    DeBiasi, M.2    Williams, J.T.3    Dani, J.A.4
  • 112
    • 2342479873 scopus 로고    scopus 로고
    • Substance-abusing schizophrenics: Do they self-medicate?
    • Goswami S, Mattoo SK, Basu D, Singh G. Substance-abusing schizophrenics: do they self-medicate? Am J Addict 2004;13: 139-50.
    • (2004) Am J Addict , vol.13 , pp. 139-150
    • Goswami, S.1    Mattoo, S.K.2    Basu, D.3    Singh, G.4
  • 113
    • 0347003609 scopus 로고    scopus 로고
    • Anhedonia, self-experience in schizophrenia, and implications for treatment
    • Juckel G, Sass L, Heinz A. Anhedonia, self-experience in schizophrenia, and implications for treatment. Pharmacopsychiatry 2003;36 suppl 3:S176-80.
    • (2003) Pharmacopsychiatry , vol.36 , Issue.SUPPL. 3
    • Juckel, G.1    Sass, L.2    Heinz, A.3
  • 114
    • 0033055995 scopus 로고    scopus 로고
    • Drug interactions with tobacco smoking. An update
    • Zevin S, Benowitz NL. Drug interactions with tobacco smoking. An update. Clin Pharmacokinet 1999;36:425-38.
    • (1999) Clin Pharmacokinet , vol.36 , pp. 425-438
    • Zevin, S.1    Benowitz, N.L.2
  • 115
    • 0026005647 scopus 로고
    • Effect of caffeine intake on psychotic in-patients
    • Zaslove MO, Russell RL, Ross E. Effect of caffeine intake on psychotic in-patients. Br J Psychiatry 1991;159:565-7.
    • (1991) Br J Psychiatry , vol.159 , pp. 565-567
    • Zaslove, M.O.1    Russell, R.L.2    Ross, E.3
  • 117
    • 2442495384 scopus 로고    scopus 로고
    • Atypical antipsychotic dosing: The effect of smoking and caffeine
    • de Leon J. Atypical antipsychotic dosing: the effect of smoking and caffeine. Psychiatr Serv 2004;55:491-3.
    • (2004) Psychiatr Serv , vol.55 , pp. 491-493
    • De Leon, J.1
  • 118
    • 20044381513 scopus 로고    scopus 로고
    • Cognitive and mood improvements of caffeine in habitual consumers and habitual non-consumers of caffeine
    • Haskell CF, Kennedy DO, Wesnes KA, Scholey AB. Cognitive and mood improvements of caffeine in habitual consumers and habitual non-consumers of caffeine. Psychopharmacology (Berl) 2005;179:813-25.
    • (2005) Psychopharmacology (Berl) , vol.179 , pp. 813-825
    • Haskell, C.F.1    Kennedy, D.O.2    Wesnes, K.A.3    Scholey, A.B.4
  • 119
    • 0034126287 scopus 로고    scopus 로고
    • Alteration of the behavioral effects of nicotine by chronic caffeine exposure
    • Tanda G, Goldberg SR. Alteration of the behavioral effects of nicotine by chronic caffeine exposure. Pharmacol Biochem Behav 2000;66:47-64.
    • (2000) Pharmacol Biochem Behav , vol.66 , pp. 47-64
    • Tanda, G.1    Goldberg, S.R.2
  • 120
    • 58249093825 scopus 로고    scopus 로고
    • Effectsofsmoking cues on caffeine urges in heavy smokers and caffeine consumers with and without schizophrenia
    • Adolfo AB, AhnAllen CG, Tidey JW. Effectsofsmoking cues on caffeine urges in heavy smokers and caffeine consumers with and without schizophrenia. Schizophr Res 2009;107:192-7.
    • (2009) Schizophr Res , vol.107 , pp. 192-197
    • Adolfo, A.B.1    AhnAllen, C.G.2    Tidey, J.W.3
  • 121
    • 33747180826 scopus 로고    scopus 로고
    • Low rates of treatment for hypertension, dyslipidemia and diabetes in schizophrenia: Data from the CATIE schizophrenia trial sample at baseline
    • Nasrallah HA, Meyer JM, Goff DC, et al. Low rates of treatment for hypertension, dyslipidemia and diabetes in schizophrenia: data from the CATIE schizophrenia trial sample at baseline. Schizophr Res 2006;86:15-22.
    • (2006) Schizophr Res , vol.86 , pp. 15-22
    • Nasrallah, H.A.1    Meyer, J.M.2    Goff, D.C.3
  • 122
    • 62549099817 scopus 로고    scopus 로고
    • Epidemiological study for the evaluation of metabolic disorders in patients with schizophrenia: The METEOR Study
    • De Hert M, Falissard B, Mauri M, Shaw K, Wetterling T. Epidemiological study for the evaluation of metabolic disorders in patients with schizophrenia: the METEOR Study. Eur Neuropsychopharmacol 2008;18(suppl 4):S444.
    • (2008) Eur Neuropsychopharmacol , vol.18 , Issue.SUPPL. 4
    • De Hert, M.1    Falissard, B.2    Mauri, M.3    Shaw, K.4    Wetterling, T.5
  • 123
    • 67650466009 scopus 로고    scopus 로고
    • Somatic hospital contacts, invasive cardiac procedures, and mortality from heart disease in patients with severe mental disorder
    • Laursen TM, Munk-Olsen T, Agerbo E, Gasse C, Mortensen PB. Somatic hospital contacts, invasive cardiac procedures, and mortality from heart disease in patients with severe mental disorder. Arch Gen Psychiatry 2009;66:713-20.
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 713-720
    • Laursen, T.M.1    Munk-Olsen, T.2    Agerbo, E.3    Gasse, C.4    Mortensen, P.B.5
  • 125
    • 21244453135 scopus 로고    scopus 로고
    • Current therapy issues and unmet clinical needs in the treatment of schizophrenia: A review of the new generation antipsychotics
    • Lublin H, Eberhard J, Levander S. Current therapy issues and unmet clinical needs in the treatment of schizophrenia: a review of the new generation antipsychotics. Int Clin Psychopharmacol 2005;20:183-98.
    • (2005) Int Clin Psychopharmacol , vol.20 , pp. 183-198
    • Lublin, H.1    Eberhard, J.2    Levander, S.3
  • 126
    • 35048827065 scopus 로고    scopus 로고
    • Adverse effects of atypical anti-psychotics: Differential risk and clinical implications
    • Haddad PM, Sharma SG. Adverse effects of atypical anti-psychotics: differential risk and clinical implications. CNS Drugs 2007;21:911-36.
    • (2007) CNS Drugs , vol.21 , pp. 911-936
    • Haddad, P.M.1    Sharma, S.G.2
  • 127
    • 0038014053 scopus 로고    scopus 로고
    • H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs
    • Kroeze WK, Hufeisen SJ, Popadak BA, et al. H1-histamine receptor affinity predicts short-term weight gain for typical and atypical antipsychotic drugs. Neuropsychopharmacology 2003;28:519-26.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 519-526
    • Kroeze, W.K.1    Hufeisen, S.J.2    Popadak, B.A.3
  • 129
    • 15744364142 scopus 로고    scopus 로고
    • Weight gain associated with the -759C/T polymorphism of the 5HT2C receptor and olanzapine
    • Ellingrod VL, Perry PJ, Ringold JC, et al. Weight gain associated with the -759C/T polymorphism of the 5HT2C receptor and olanzapine. Am J Med Genet B Neuropsychiatr Genet 2005;134B:76-8.
    • (2005) Am J Med Genet B Neuropsychiatr Genet , vol.134 B , pp. 76-78
    • Ellingrod, V.L.1    Perry, P.J.2    Ringold, J.C.3
  • 131
    • 47949104798 scopus 로고    scopus 로고
    • The role of exercise and PGC1alpha in inflammation and chronic disease
    • Handschin C, Spiegelman BM. The role of exercise and PGC1alpha in inflammation and chronic disease. Nature 2008; 454:463-9.
    • (2008) Nature , vol.454 , pp. 463-469
    • Handschin, C.1    Spiegelman, B.M.2
  • 132
    • 0032749573 scopus 로고    scopus 로고
    • Relationship between low cardiorespiratory fitness and mortality in normal-weight, overweight, and obese men
    • Wei M, Kampert JB, Barlow CE, et al. Relationship between low cardiorespiratory fitness and mortality in normal-weight, overweight, and obese men. JAMA 1999;282: 1547-53.
    • (1999) JAMA , vol.282 , pp. 1547-1553
    • Wei, M.1    Kampert, J.B.2    Barlow, C.E.3
  • 134
    • 42249090877 scopus 로고    scopus 로고
    • A life course of adiposity and dementia
    • Gustafson D. A life course of adiposity and dementia. Eur J Pharmacol 2008;585:163-75.
    • (2008) Eur J Pharmacol , vol.585 , pp. 163-175
    • Gustafson, D.1
  • 135
    • 84870540270 scopus 로고    scopus 로고
    • Energy intake and exercise as determinants of brain health and vulnerability to injury and disease
    • Mattson MP. Energy intake and exercise as determinants of brain health and vulnerability to injury and disease. Cell Metab 2012;16:706-22.
    • (2012) Cell Metab , vol.16 , pp. 706-722
    • Mattson, M.P.1
  • 136
    • 18744366088 scopus 로고    scopus 로고
    • Second-generation (atypical) antipsychotics and metabolic effects: A comprehensive literature review
    • Newcomer JW. Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review. CNS Drugs 2005;19 suppl 1:1-93.
    • (2005) CNS Drugs , vol.19 , Issue.SUPPL. 1 , pp. 1-93
    • Newcomer, J.W.1
  • 137
    • 2442509785 scopus 로고    scopus 로고
    • Hyperlipidemia in persons using antipsychotic medication: A general population-based birth cohort study
    • Saari K, Koponen H, Laitinen J, et al. Hyperlipidemia in persons using antipsychotic medication: a general population-based birth cohort study. J Clin Psychiatry 2004;65:547-50.
    • (2004) J Clin Psychiatry , vol.65 , pp. 547-550
    • Saari, K.1    Koponen, H.2    Laitinen, J.3
  • 138
    • 1842739590 scopus 로고    scopus 로고
    • Adverse metabolic effects associated with atypical antipsychotics: Literature review and clinical implications
    • Melkersson K, Dahl ML. Adverse metabolic effects associated with atypical antipsychotics: literature review and clinical implications. Drugs 2004;64:701-23.
    • (2004) Drugs , vol.64 , pp. 701-723
    • Melkersson, K.1    Dahl, M.L.2
  • 140
    • 0034954068 scopus 로고    scopus 로고
    • Major system toxicities and side effects of anticonvulsants
    • Swann AC. Major system toxicities and side effects of anticonvulsants. J Clin Psychiatry 2001;62 suppl 14:16-21.
    • (2001) J Clin Psychiatry , vol.62 , Issue.SUPPL. 14 , pp. 16-21
    • Swann, A.C.1
  • 141
    • 79953054796 scopus 로고    scopus 로고
    • Diabetes and depression? Secular trends in the use of antidepressants among persons with diabetes in Finland in 1997-2007
    • Manderbacka K, Sund R, Koski S, Keskimaki I, Elovainio M. Diabetes and depression? Secular trends in the use of antidepressants among persons with diabetes in Finland in 1997-2007. Pharmacoepidemiol Drug Saf 2011;20:338-43.
    • (2011) Pharmacoepidemiol Drug Saf , vol.20 , pp. 338-343
    • Manderbacka, K.1    Sund, R.2    Koski, S.3    Keskimaki, I.4    Elovainio, M.5
  • 142
    • 77950891328 scopus 로고    scopus 로고
    • Subjective tolerability of antipsychotic medications and the emerging science of subjective tolerability disorders
    • Awad AG. Subjective tolerability of antipsychotic medications and the emerging science of subjective tolerability disorders. Expert Rev Pharmacoecon Outcomes Res 2010;10:1-4.
    • (2010) Expert Rev Pharmacoecon Outcomes Res , vol.10 , pp. 1-4
    • Awad, A.G.1
  • 143
    • 2642515398 scopus 로고    scopus 로고
    • Is neuroleptic dysphoria a variant of drug-induced extrapyramidal side effects?
    • Voruganti LP, Awad AG. Is neuroleptic dysphoria a variant of drug-induced extrapyramidal side effects? Can J Psychiatry 2004;49:285-9.
    • (2004) Can J Psychiatry , vol.49 , pp. 285-289
    • Voruganti, L.P.1    Awad, A.G.2
  • 144
    • 0036886986 scopus 로고    scopus 로고
    • Safety and tolerability: How do newer generation "atypical" antipsychotics compare?
    • Tandon R. Safety and tolerability: how do newer generation "atypical" antipsychotics compare? Psychiatr Q 2002;73: 297-311.
    • (2002) Psychiatr Q , vol.73 , pp. 297-311
    • Tandon, R.1
  • 145
    • 34247533866 scopus 로고    scopus 로고
    • Adverse subjective experience with antipsychotics and its relationship to striatal and extrastriatal D2 receptors: A PET study in schizophrenia
    • Mizrahi R, Rusjan P, Agid O, et al. Adverse subjective experience with antipsychotics and its relationship to striatal and extrastriatal D2 receptors: a PET study in schizophrenia. Am J Psychiatry 2007;164:630-7.
    • (2007) Am J Psychiatry , vol.164 , pp. 630-637
    • Mizrahi, R.1    Rusjan, P.2    Agid, O.3
  • 146
    • 84889958809 scopus 로고    scopus 로고
    • Role of dopamine in pleasure, reward and subjective responses to drugs. The neuropsycho-pharmacology of quality of life in schizophrenia
    • Ritsner MS, Awad AG, eds. Dordrecht: Springer
    • Voruganti LNP, Awad AG. Role of dopamine in pleasure, reward and subjective responses to drugs. The neuropsycho-pharmacology of quality of life in schizophrenia. In: Ritsner MS, Awad AG, eds. Quality of life impairment in schizophrenia, mood and anxiety disorders. Dordrecht: Springer, 2007.
    • (2007) Quality of Life Impairment in Schizophrenia, Mood and Anxiety Disorders
    • Voruganti, L.N.P.1    Awad, A.G.2
  • 147
    • 0037313398 scopus 로고    scopus 로고
    • Subjective experience and D2 receptor occupancy in patients with recent-onset schizophrenia treated with low-dose olanzapine or haloperidol: A randomized, double-blind study
    • de Haan L, van Bruggen M, Lavalaye J, Booij J, Dingemans PM, Linszen D. Subjective experience and D2 receptor occupancy in patients with recent-onset schizophrenia treated with low-dose olanzapine or haloperidol: a randomized, double-blind study. Am J Psychiatry 2003;160:303-9.
    • (2003) Am J Psychiatry , vol.160 , pp. 303-309
    • De Haan, L.1    Van Bruggen, M.2    Lavalaye, J.3    Booij, J.4    Dingemans, P.M.5    Linszen, D.6
  • 148
    • 0029946719 scopus 로고    scopus 로고
    • High levels of dopamine D2 receptor occupancy with low-dose haloperidol treatment: A PET study
    • Kapur S, Remington G, Jones C, et al. High levels of dopamine D2 receptor occupancy with low-dose haloperidol treatment: a PET study. Am J Psychiatry 1996;153:948-50.
    • (1996) Am J Psychiatry , vol.153 , pp. 948-950
    • Kapur, S.1    Remington, G.2    Jones, C.3
  • 149
    • 0027520871 scopus 로고
    • Central D2-dopamine receptor occupancy in relation to antipsychotic drug effects: A double-blind PET study of schizophrenic patients
    • Nordstrom AL, Farde L, Wiesel FA, et al. Central D2-dopamine receptor occupancy in relation to antipsychotic drug effects: a double-blind PET study of schizophrenic patients. Biol Psychiatry 1993;33:227-35.
    • (1993) Biol Psychiatry , vol.33 , pp. 227-235
    • Nordstrom, A.L.1    Farde, L.2    Wiesel, F.A.3
  • 150
    • 0034109940 scopus 로고    scopus 로고
    • Antipsychotic agents differ in how fast they come off the dopamine D2 receptors. Implications for atypical antipsychotic action
    • Kapur S, Seeman P. Antipsychotic agents differ in how fast they come off the dopamine D2 receptors. Implications for atypical antipsychotic action. J Psychiatry Neurosci 2000;25:161-6.
    • (2000) J Psychiatry Neurosci , vol.25 , pp. 161-166
    • Kapur, S.1    Seeman, P.2
  • 151
    • 0030785601 scopus 로고    scopus 로고
    • Neuroleptic dysphoria may be the missing link between schizophrenia and substance abuse
    • Voruganti LN, Heslegrave RJ, Awad AG. Neuroleptic dysphoria may be the missing link between schizophrenia and substance abuse. J Nerv Ment Dis 1997;185:463-5.
    • (1997) J Nerv Ment Dis , vol.185 , pp. 463-465
    • Voruganti, L.N.1    Heslegrave, R.J.2    Awad, A.G.3
  • 152
    • 0642366895 scopus 로고    scopus 로고
    • Pharmacotherapy for schizophrenia and co-occurring substance use disorders
    • Noordsy DL, Green AI. Pharmacotherapy for schizophrenia and co-occurring substance use disorders. Curr Psychiatry Rep 2003;5:340-6.
    • (2003) Curr Psychiatry Rep , vol.5 , pp. 340-346
    • Noordsy, D.L.1    Green, A.I.2
  • 153
    • 0028119158 scopus 로고
    • Clozapine attenuates cocaine conditioned place preference
    • Kosten TA, Nestler EJ. Clozapine attenuates cocaine conditioned place preference. Life Sci 1994;55:PL9-14.
    • (1994) Life Sci , vol.55
    • Kosten, T.A.1    Nestler, E.J.2
  • 155
    • 12644293806 scopus 로고    scopus 로고
    • Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: Evidence from a novel positron emission tomography method
    • Breier A, Su TP, Saunders R, et al. Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: evidence from a novel positron emission tomography method. Proc Natl Acad Sci U S A 1997;94:2569-74.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 2569-2574
    • Breier, A.1    Su, T.P.2    Saunders, R.3
  • 156
    • 0029010819 scopus 로고
    • SPECT imaging of striatal dopamine release after amphetamine challenge
    • Laruelle M, Abi-Dargham A, van Dyck CH, et al. SPECT imaging of striatal dopamine release after amphetamine challenge. J Nucl Med 1995;36:1182-90.
    • (1995) J Nucl Med , vol.36 , pp. 1182-1190
    • Laruelle, M.1    Abi-Dargham, A.2    Van Dyck, C.H.3
  • 157
    • 0030799746 scopus 로고    scopus 로고
    • PET study of competition between intravenous cocaine and [11C]raclopride at dopamine receptors in human subjects
    • Schlaepfer TE, Pearlson GD, Wong DF, Marenco S, Dannals RF. PET study of competition between intravenous cocaine and [11C]raclopride at dopamine receptors in human subjects. Am J Psychiatry 1997;154:1209-13.
    • (1997) Am J Psychiatry , vol.154 , pp. 1209-1213
    • Schlaepfer, T.E.1    Pearlson, G.D.2    Wong, D.F.3    Marenco, S.4    Dannals, R.F.5
  • 158
    • 15744398700 scopus 로고    scopus 로고
    • Delta-9-tetrahydrocannabinol effects in schizophrenia: Implications for cognition, psychosis, and addiction
    • D'Souza DC, Abi-Saab WM, Madonick S, et al. Delta-9-tetrahydrocannabinol effects in schizophrenia: implications for cognition, psychosis, and addiction. Biol Psychiatry 2005; 57:594-608.
    • (2005) Biol Psychiatry , vol.57 , pp. 594-608
    • D'Souza, D.C.1    Abi-Saab, W.M.2    Madonick, S.3
  • 159
    • 33745119452 scopus 로고    scopus 로고
    • Striatal dopamine release and family history of alcoholism
    • Munro CA, McCaul ME, Oswald LM, et al. Striatal dopamine release and family history of alcoholism. Alcohol Clin Exp Res 2006;30:1143-51.
    • (2006) Alcohol Clin Exp Res , vol.30 , pp. 1143-1151
    • Munro, C.A.1    McCaul, M.E.2    Oswald, L.M.3
  • 160
    • 15444373514 scopus 로고    scopus 로고
    • Relationships among ventral striatal dopamine release, cortisol secretion, and subjective responses to amphetamine
    • Oswald LM, Wong DF, McCaul M, et al. Relationships among ventral striatal dopamine release, cortisol secretion, and subjective responses to amphetamine. Neuropsychopharmacology 2005;30:821-32.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 821-832
    • Oswald, L.M.1    Wong, D.F.2    McCaul, M.3
  • 162
    • 33745404437 scopus 로고    scopus 로고
    • Impact of haloperidol, a dopamine D2 antagonist, on cognition and mood
    • Saeedi H, Remington G, Christensen BK. Impact of haloperidol, a dopamine D2 antagonist, on cognition and mood. Schizophr Res 2006;85:222-31.
    • (2006) Schizophr Res , vol.85 , pp. 222-231
    • Saeedi, H.1    Remington, G.2    Christensen, B.K.3
  • 163
    • 77749252588 scopus 로고    scopus 로고
    • The effect of dopamine partial agonists on the nicotine dependency in patients with schizophrenia
    • Kim SH, Han DH, Joo SY, Min KJ. The effect of dopamine partial agonists on the nicotine dependency in patients with schizophrenia. Hum Psychopharmacol 2010;25:187-90.
    • (2010) Hum Psychopharmacol , vol.25 , pp. 187-190
    • Kim, S.H.1    Han, D.H.2    Joo, S.Y.3    Min, K.J.4
  • 164
    • 28344456936 scopus 로고    scopus 로고
    • Occupancy of dopamine D2 receptors by antipsychotic drugs is related to nicotine addiction in young patients with schizophrenia
    • de Haan L, Booij J, Lavalaye J, van Amelsvoort T, Linszen D. Occupancy of dopamine D2 receptors by antipsychotic drugs is related to nicotine addiction in young patients with schizophrenia. Psychopharmacology (Berl) 2006;183:500-5.
    • (2006) Psychopharmacology (Berl) , vol.183 , pp. 500-505
    • De Haan, L.1    Booij, J.2    Lavalaye, J.3    Van Amelsvoort, T.4    Linszen, D.5
  • 166
    • 2442565645 scopus 로고    scopus 로고
    • Chronic nicotine and smoking treatment increases dopamine transporter mRNA expression in the rat midbrain
    • Li S, Kim KY, Kim JH, Park MS, Bahk JY, Kim MO. Chronic nicotine and smoking treatment increases dopamine transporter mRNA expression in the rat midbrain. Neurosci Lett 2004;363:29-32.
    • (2004) Neurosci Lett , vol.363 , pp. 29-32
    • Li, S.1    Kim, K.Y.2    Kim, J.H.3    Park, M.S.4    Bahk, J.Y.5    Kim, M.O.6
  • 167
    • 0242667143 scopus 로고    scopus 로고
    • Nicotinic receptor-mediated regulation of the dopamine transporter in rat prefrontocortical slices following chronic in vivo administration of nicotine
    • Drew AE, Werling LL. Nicotinic receptor-mediated regulation of the dopamine transporter in rat prefrontocortical slices following chronic in vivo administration of nicotine. Schizophr Res 2003;65:47-55.
    • (2003) Schizophr Res , vol.65 , pp. 47-55
    • Drew, A.E.1    Werling, L.L.2
  • 168
    • 0036789821 scopus 로고    scopus 로고
    • Nicotine decreases bradykinesia-rigidity in haloperidoltreated patients with schizophrenia
    • Yang YK, Nelson L, Kamaraju L, Wilson W, McEvoy JP. Nicotine decreases bradykinesia-rigidity in haloperidoltreated patients with schizophrenia. Neuropsychopharmacology 2002;27:684-6.
    • (2002) Neuropsychopharmacology , vol.27 , pp. 684-686
    • Yang, Y.K.1    Nelson, L.2    Kamaraju, L.3    Wilson, W.4    McEvoy, J.P.5
  • 169
    • 0030827472 scopus 로고    scopus 로고
    • Treatment of neuroleptic-induced akathisia with nicotine patches
    • Anfang MK, Pope HG Jr. Treatment of neuroleptic-induced akathisia with nicotine patches. Psychopharmacology (Berl) 1997;134:153-6.
    • (1997) Psychopharmacology (Berl) , vol.134 , pp. 153-156
    • Anfang, M.K.1    Pope Jr., H.G.2
  • 170
    • 0026800996 scopus 로고
    • Cigarette smoking in schizophrenia: Relationship to psychopathology and medication side effects
    • Goff DC, Henderson DC, Amico E. Cigarette smoking in schizophrenia: relationship to psychopathology and medication side effects. Am J Psychiatry 1992;149:1189-94.
    • (1992) Am J Psychiatry , vol.149 , pp. 1189-1194
    • Goff, D.C.1    Henderson, D.C.2    Amico, E.3
  • 172
    • 0023748070 scopus 로고
    • Tardive dyskinesia, dopamine receptors, and neuroleptic damage to cell membranes
    • Seeman P. Tardive dyskinesia, dopamine receptors, and neuroleptic damage to cell membranes. J Clin Psychopharmacol 1988;8:3S-9S.
    • (1988) J Clin Psychopharmacol , vol.8
    • Seeman, P.1
  • 173
    • 1442264400 scopus 로고    scopus 로고
    • Association of anticholinergic load with impairment of complex attention and memory in schizophrenia
    • Minzenberg MJ, Poole JH, Benton C, Vinogradov S. Association of anticholinergic load with impairment of complex attention and memory in schizophrenia. Am J Psychiatry 2004;161:116-24.
    • (2004) Am J Psychiatry , vol.161 , pp. 116-124
    • Minzenberg, M.J.1    Poole, J.H.2    Benton, C.3    Vinogradov, S.4
  • 174
    • 69949103030 scopus 로고    scopus 로고
    • The cognitive cost of anticholinergic burden: Decreased response to cognitive training in schizophrenia
    • Vinogradov S, Fisher M, Warm H, Holland C, Kirshner MA, Pollock BG. The cognitive cost of anticholinergic burden: decreased response to cognitive training in schizophrenia. Am J Psychiatry 2009;166:1055-62.
    • (2009) Am J Psychiatry , vol.166 , pp. 1055-1062
    • Vinogradov, S.1    Fisher, M.2    Warm, H.3    Holland, C.4    Kirshner, M.A.5    Pollock, B.G.6
  • 175
    • 0030297344 scopus 로고    scopus 로고
    • Nicotine-haloperidol interactions and cognitive performance in schizophrenics
    • Levin ED, Wilson W, Rose JE, McEvoy J. Nicotine-haloperidol interactions and cognitive performance in schizophrenics. Neuropsychopharmacology 1996;15:429-36.
    • (1996) Neuropsychopharmacology , vol.15 , pp. 429-436
    • Levin, E.D.1    Wilson, W.2    Rose, J.E.3    McEvoy, J.4
  • 176
    • 11844263996 scopus 로고    scopus 로고
    • Tobacco use in schizophrenia: A study of cotinine concentrations in the saliva of patients and controls
    • Strand JE, Nyback H. Tobacco use in schizophrenia: a study of cotinine concentrations in the saliva of patients and controls. Eur Psychiatry 2005;20:50-4.
    • (2005) Eur Psychiatry , vol.20 , pp. 50-54
    • Strand, J.E.1    Nyback, H.2
  • 177
    • 33747159598 scopus 로고    scopus 로고
    • Does smoking reduce akathisia? Testing a narrow version of the self-medication hypothesis
    • de Leon J, Diaz FJ, Aguilar MC, Jurado D, Gurpegui M. Does smoking reduce akathisia? Testing a narrow version of the self-medication hypothesis. Schizophr Res 2006;86: 256-68.
    • (2006) Schizophr Res , vol.86 , pp. 256-268
    • De Leon, J.1    Diaz, F.J.2    Aguilar, M.C.3    Jurado, D.4    Gurpegui, M.5
  • 178
  • 179
    • 0030758520 scopus 로고    scopus 로고
    • Augmentation of opioid induced antinociception by the atypical antipsychotic drug risperidone in mice
    • Schreiber S, Backer MM, Weizman R, Pick CG. Augmentation of opioid induced antinociception by the atypical antipsychotic drug risperidone in mice. Neurosci Lett 1997; 228:25-8.
    • (1997) Neurosci Lett , vol.228 , pp. 25-28
    • Schreiber, S.1    Backer, M.M.2    Weizman, R.3    Pick, C.G.4
  • 180
    • 0032885115 scopus 로고    scopus 로고
    • The atypical neuroleptics clozapine and olanzapine differ regarding their antinociceptive mechanisms and potency
    • Schreiber S, Getslev V, Backer MM, Weizman R, Pick CG. The atypical neuroleptics clozapine and olanzapine differ regarding their antinociceptive mechanisms and potency. Pharmacol Biochem Behav 1999;64:75-80.
    • (1999) Pharmacol Biochem Behav , vol.64 , pp. 75-80
    • Schreiber, S.1    Getslev, V.2    Backer, M.M.3    Weizman, R.4    Pick, C.G.5
  • 181
    • 0142138311 scopus 로고    scopus 로고
    • The antinociceptive effect of amisulpride in mice is mediated through opioid mechanisms
    • Weizman T, Pick CG, Backer MM, Rigai T, Bloch M, Schreiber S. The antinociceptive effect of amisulpride in mice is mediated through opioid mechanisms. Eur J Pharmacol 2003;478:155-9.
    • (2003) Eur J Pharmacol , vol.478 , pp. 155-159
    • Weizman, T.1    Pick, C.G.2    Backer, M.M.3    Rigai, T.4    Bloch, M.5    Schreiber, S.6
  • 182
    • 0036345129 scopus 로고    scopus 로고
    • Improvement in the level of psychosocial functioning in chronic pain patients with the use of risperidone
    • Fe-Bornstein M, Watt SD, Gitlin MC. Improvement in the level of psychosocial functioning in chronic pain patients with the use of risperidone. Pain Med 2002;3:128-31.
    • (2002) Pain Med , vol.3 , pp. 128-131
    • Fe-Bornstein, M.1    Watt, S.D.2    Gitlin, M.C.3
  • 187
    • 0037390212 scopus 로고    scopus 로고
    • Nucleus accumbens muopioids regulate intake of a high-fat diet via activation of a distributed brain network
    • Will MJ, Franzblau EB, Kelley AE. Nucleus accumbens muopioids regulate intake of a high-fat diet via activation of a distributed brain network. J Neurosci 2003;23:2882-8.
    • (2003) J Neurosci , vol.23 , pp. 2882-2888
    • Will, M.J.1    Franzblau, E.B.2    Kelley, A.E.3
  • 189
    • 13044268459 scopus 로고    scopus 로고
    • Predictors of relapse following response from a first episode of schizophrenia or schizoaffective disorder
    • Robinson D, Woerner MG, Alvir JM, et al. Predictors of relapse following response from a first episode of schizophrenia or schizoaffective disorder. Arch Gen Psychiatry 1999;56:241-7.
    • (1999) Arch Gen Psychiatry , vol.56 , pp. 241-247
    • Robinson, D.1    Woerner, M.G.2    Alvir, J.M.3
  • 190
    • 30344459999 scopus 로고    scopus 로고
    • Risk and protection in prodromal schizophrenia: Ethical implications for clinical practice and future research
    • Haroun N, Dunn L, Haroun A, Cadenhead KS. Risk and protection in prodromal schizophrenia: ethical implications for clinical practice and future
    • (2006) Schizophr Bull , vol.32 , pp. 166-178
    • Haroun, N.1    Dunn, L.2    Haroun, A.3    Cadenhead, K.S.4
  • 191
    • 85047695195 scopus 로고    scopus 로고
    • Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis
    • McGlashan TH, Zipursky RB, Perkins D, et al. Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis. Am J Psychiatry 2006;163:790-9.
    • (2006) Am J Psychiatry , vol.163 , pp. 790-799
    • McGlashan, T.H.1    Zipursky, R.B.2    Perkins, D.3
  • 192
    • 0037400949 scopus 로고    scopus 로고
    • The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis. II. Baseline characteristics of the "prodromal" sample
    • Miller TJ, Zipursky RB, Perkins D, et al. The PRIME North America randomized double-blind clinical trial of olanzapine versus placebo in patients at risk of being prodromally symptomatic for psychosis. II. Baseline characteristics of the "prodromal" sample. Schizophr Res 2003;61:19-30.
    • (2003) Schizophr Res , vol.61 , pp. 19-30
    • Miller, T.J.1    Zipursky, R.B.2    Perkins, D.3
  • 193
    • 44949167544 scopus 로고    scopus 로고
    • Cognitive behavior therapy for schizophrenia: Effect sizes, clinical models, and methodological rigor
    • Wykes T, Steel C, Everitt B, Tarrier N. Cognitive behavior therapy for schizophrenia: effect sizes, clinical models, and methodological rigor. Schizophr Bull 2008;34:523-37.
    • (2008) Schizophr Bull , vol.34 , pp. 523-537
    • Wykes, T.1    Steel, C.2    Everitt, B.3    Tarrier, N.4
  • 196
    • 33847246338 scopus 로고    scopus 로고
    • Serious mental illness and physical health problems: A discussion paper
    • Robson D, Gray R. Serious mental illness and physical health problems: a discussion paper. Int J Nurs Stud 2007; 44:457-66.
    • (2007) Int J Nurs Stud , vol.44 , pp. 457-466
    • Robson, D.1    Gray, R.2
  • 201
    • 0042338703 scopus 로고    scopus 로고
    • Vocational rehabilitation in schizophrenia and other psychotic disorders: A literature review and meta-analysis of randomized controlled trials
    • Twamley EW, Jeste DV, Lehman AF. Vocational rehabilitation in schizophrenia and other psychotic disorders: a literature review and meta-analysis of randomized controlled trials. J Nerv Ment Dis 2003;191:515-23.
    • (2003) J Nerv Ment Dis , vol.191 , pp. 515-523
    • Twamley, E.W.1    Jeste, D.V.2    Lehman, A.F.3
  • 202
    • 0041328134 scopus 로고    scopus 로고
    • Clinical interventions for treatment non-adherence in psychosis: Meta-analysis
    • Nose M, Barbui C, Gray R, Tansella M. Clinical interventions for treatment non-adherence in psychosis: meta-analysis. Br J Psychiatry 2003;183:197-206.
    • (2003) Br J Psychiatry , vol.183 , pp. 197-206
    • Nose, M.1    Barbui, C.2    Gray, R.3    Tansella, M.4
  • 203
    • 34548175719 scopus 로고    scopus 로고
    • Use of intensive case management to reduce time in hospital in people with severe mental illness: Systematic review and meta-regression
    • Burns T, Catty J, Dash M, Roberts C, Lockwood A, Marshall M. Use of intensive case management to reduce time in hospital in people with severe mental illness: systematic review and meta-regression. BMJ 2007;335:336.
    • (2007) BMJ , vol.335 , pp. 336
    • Burns, T.1    Catty, J.2    Dash, M.3    Roberts, C.4    Lockwood, A.5    Marshall, M.6
  • 204
    • 67649177544 scopus 로고    scopus 로고
    • Topiramate add-on treatment in schizophrenia: A randomised, double-blind, placebocontrolled clinical trial
    • Afshar H, Roohafza H, Mousavi G, et al. Topiramate add-on treatment in schizophrenia: a randomised, double-blind, placebocontrolled clinical trial. J Psychopharmacol 2009;23:157-62.
    • (2009) J Psychopharmacol , vol.23 , pp. 157-162
    • Afshar, H.1    Roohafza, H.2    Mousavi, G.3
  • 206
    • 0642282677 scopus 로고    scopus 로고
    • Effects of environmental enrichment at ages 3-5 years on schizotypal personality and antisocial behavior at ages 17 and 23 years
    • Raine A, Mellingen K, Liu J, Venables P, Mednick SA. Effects of environmental enrichment at ages 3-5 years on schizotypal personality and antisocial behavior at ages 17 and 23 years. Am J Psychiatry 2003;160:1627-35.
    • (2003) Am J Psychiatry , vol.160 , pp. 1627-1635
    • Raine, A.1    Mellingen, K.2    Liu, J.3    Venables, P.4    Mednick, S.A.5
  • 207
    • 0032937814 scopus 로고    scopus 로고
    • Biology and the future of psychoanalysis: A new intellectual framework for psychiatry revisited
    • Kandel ER. Biology and the future of psychoanalysis: a new intellectual framework for psychiatry revisited. Am J Psychiatry 1999;156:505-24.
    • (1999) Am J Psychiatry , vol.156 , pp. 505-524
    • Kandel, E.R.1
  • 208
    • 68949188168 scopus 로고    scopus 로고
    • Is serum brain-derived neurotrophic factor a biomarker for cognitive enhancement in schizophrenia?
    • Vinogradov S, Fisher M, Holland C, Shelly W, Wolkowitz O, Mellon SH. Is serum brain-derived neurotrophic factor a biomarker for cognitive enhancement in schizophrenia? Biol Psychiatry 2009;66:549-53.
    • (2009) Biol Psychiatry , vol.66 , pp. 549-553
    • Vinogradov, S.1    Fisher, M.2    Holland, C.3    Shelly, W.4    Wolkowitz, O.5    Mellon, S.H.6
  • 209
    • 48949116396 scopus 로고    scopus 로고
    • Integrating biological measures into the design and evaluation of preventive interventions
    • Cicchetti D, Gunnar MR. Integrating biological measures into the design and evaluation of preventive interventions. Dev Psychopathol 2008;20:737-43.
    • (2008) Dev Psychopathol , vol.20 , pp. 737-743
    • Cicchetti, D.1    Gunnar, M.R.2
  • 210
    • 40849133755 scopus 로고    scopus 로고
    • Central effects of stress hormones in health and disease: Understanding the protective and damaging effects of stress and stress mediators
    • McEwen BS. Central effects of stress hormones in health and disease: understanding the protective and damaging effects of stress and stress mediators. Eur J Pharmacol 2008;583:174-85.
    • (2008) Eur J Pharmacol , vol.583 , pp. 174-185
    • McEwen, B.S.1


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