Ligands for glaucoma-associated myocilin discovered by a generic binding assay

ACS Chemical Biology

Volumn 9, Issue 2, 2014, Pages 517-525

  Orwig, Susan D ^a   Chi, Pamela V ^a   Du, Yuhong ^b   Hill, Shannon E ^a   Cavitt, Marchello A ^a   Suntharalingam, Amrithaa ^c   Turnage, Katherine C ^a   Dickey, Chad A ^c   France, Stefan ^a   Fu, Haian ^b   Lieberman, Raquel L ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 (3,5 DIBROMO 4 HYDROXYBENZYLIDENE) 1,3 DIHYDRO 5 IODO 2 INDOLONE; AMYLOID; APIGENIN; AURINTRICARBOXYLIC ACID; CIBACRON BLUE F3GA; CIS DIETHYL CHRYSENEDIOL TETRAHYDRO 2,8 CHRYSENEDIOL; ISOLIQUIRITIGENIN; LIGAND; MORIN; MYOCILIN; MYRICETIN; NICLOSAMIDE; PHLORETIN; PICEATANNOL; PROTEIN INHIBITOR; QUERCETIN; ROTTLERIN; TYRPHOSTIN AG 879; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING ASSAY; CONTROLLED STUDY; GLAUCOMA; IN VITRO STUDY; MOLECULE; MUTATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION; SURFACE PLASMON RESONANCE;

CYTOSKELETAL PROTEINS; DRUG EVALUATION, PRECLINICAL; EXTRACELLULAR MATRIX PROTEINS; EYE PROTEINS; GLAUCOMA, OPEN-ANGLE; GLYCOPROTEINS; HUMANS; LIGANDS; MODELS, MOLECULAR; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP; SURFACE PLASMON RESONANCE;

EID: 84896734377     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb4007776     Document Type: Article

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