Decrypting the biochemical function of an essential gene from Streptococcus pneumoniae using ThermoFluor® technology

Journal of Biological Chemistry

Volumn 280, Issue 12, 2005, Pages 11704-11712

  Carver, Theodore E ^a,c   Bordeau, Brian ^a   Cummings, Maxwell D ^a   Petrella, Eugene C ^a,d   Pucci, Michael J ^b,e   Zawadzke, Laura E ^b,f   Dougherty, Brian A ^b   Tredup, Jeffrey A ^b   Bryson, James W ^b   Yanchunas Jr , Joseph ^b   Doyle, Michael L ^b   Witmer, Mark R ^b   Nelen, Marina I ^a   DesJarlais, Renee L ^a   Jaeger, Edward P ^a   Devine, Heather ^a   Asel, Eric D ^a   Springer, Barry A ^a   Bone, Roger ^a   Salemme, F Raymond ^a,g   Todd, Matthew J ^a   more..

^a JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

^b BRISTOL MYERS SQUIBB PHARMACEUTICAL RESEARCH INSTITUTE   (United States)

^c Ceptor Corp   (United States)

^d Daiamed Pharmaceuticals   (United States)

^e Achillion Pharmaceuticals   (United States)

^f PFIZER INC   (United States)

^g Linguagen Corp   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; DRUG PRODUCTS; PROTEINS; SUGARS;

BIOLOGICAL FUNCTIONS; CANESCIN A; ENZYMATIC COFACTOR FUNCTION; STREPTOCOCCUS PNEUMONIAE;

GENES;

ANTIFUNGAL AGENT; CANESCIN A; NUCLEOTIDE; PYRIDOXAL 5 PHOSPHATE; PYRIDOXAMINE PHOSPHATE; SUGAR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BIOCHEMISTRY; ENZYME MODIFICATION; ESSENTIAL GENE; GENE EXPRESSION; GENE LIBRARY; GENE PROBE; GENOMICS; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEOMICS; SCREENING; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STEADY STATE; STREPTOCOCCUS PNEUMONIAE; THERMOSTABILITY;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BENZOPYRANS; DIMERIZATION; FURANS; GENES, ESSENTIAL; LIGANDS; MOLECULAR SEQUENCE DATA; NUCLEOSIDE DIPHOSPHATE SUGARS; PYRIDOXAL PHOSPHATE; PYRIDOXAMINE; STREPTOCOCCUS PNEUMONIAE; TRANSAMINASES;

STREPTOCOCCUS PNEUMONIAE;

EID: 20144384268     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M413278200     Document Type: Article

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