-
2
-
-
0032578846
-
Medical management of glaucoma
-
Alward W.L. Medical management of glaucoma N. Engl. J. Med. 339 1998 1298 1307
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 1298-1307
-
-
Alward, W.L.1
-
3
-
-
64249121678
-
Biological properties of trabecular meshwork cells
-
Gasiorowski J., and Russell P. Biological properties of trabecular meshwork cells Exp. Eye Res. 88 2009 671 675
-
(2009)
Exp. Eye Res.
, vol.88
, pp. 671-675
-
-
Gasiorowski, J.1
Russell, P.2
-
4
-
-
0036269833
-
The Ocular Hypertension Treatment Study: A randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma
-
discussion, 829-830
-
Kass M.A., Heuer D.K., Higginbotham E.J., Johnson C.A., Keltner J.L., and Miller J.P. The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma Arch. Ophthalmol. 120 2002 701 713 discussion, 829-830
-
(2002)
Arch. Ophthalmol.
, vol.120
, pp. 701-713
-
-
Kass, M.A.1
Heuer, D.K.2
Higginbotham, E.J.3
Johnson, C.A.4
Keltner, J.L.5
Miller, J.P.6
-
5
-
-
64249133288
-
Glaucoma-associated myocilin: A better understanding but much more to learn
-
Resch Z., and Fautsch M. Glaucoma-associated myocilin: a better understanding but much more to learn Exp. Eye Res. 88 2009 704 712
-
(2009)
Exp. Eye Res.
, vol.88
, pp. 704-712
-
-
Resch, Z.1
Fautsch, M.2
-
7
-
-
0032725031
-
A cellular assay distinguishes normal and mutant TIGR/myocilin protein
-
Zhou Z., and Vollrath D. A cellular assay distinguishes normal and mutant TIGR/myocilin protein Hum. Mol. Genet. 8 1999 2221 2228
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 2221-2228
-
-
Zhou, Z.1
Vollrath, D.2
-
8
-
-
34047112986
-
Glaucoma-causing myocilin mutants require the peroxisomal targeting signal-1 receptor (PTS1R) to elevate intraocular pressure
-
Shepard A.R., Jacobson N., Millar J.C., Pang I.H., Steely H.T., and Searby C.C. Glaucoma-causing myocilin mutants require the peroxisomal targeting signal-1 receptor (PTS1R) to elevate intraocular pressure Hum. Mol. Genet. 16 2006 609 617
-
(2006)
Hum. Mol. Genet.
, vol.16
, pp. 609-617
-
-
Shepard, A.R.1
Jacobson, N.2
Millar, J.C.3
Pang, I.H.4
Steely, H.T.5
Searby, C.C.6
-
9
-
-
2942718944
-
Reversal of mutant myocilin non-secretion and cell killing: Implications for glaucoma
-
Liu Y., and Vollrath D. Reversal of mutant myocilin non-secretion and cell killing: implications for glaucoma Hum. Mol. Genet. 13 2004 1193 1204
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 1193-1204
-
-
Liu, Y.1
Vollrath, D.2
-
10
-
-
44649105940
-
Transgenic mice expressing the Tyr437His mutant of human myocilin protein develop glaucoma
-
Zhou Y., Grinchuk O., and Tomarev S.I. Transgenic mice expressing the Tyr437His mutant of human myocilin protein develop glaucoma Invest. Ophthalmol. Vis. Sci. 49 2008 1932 1939
-
(2008)
Invest. Ophthalmol. Vis. Sci.
, vol.49
, pp. 1932-1939
-
-
Zhou, Y.1
Grinchuk, O.2
Tomarev, S.I.3
-
11
-
-
33751106672
-
Expression of mutated mouse myocilin induces open-angle glaucoma in transgenic mice
-
Senatorov V., Malyukova I., Fariss R., Wawrousek E.F., Swaminathan S., Sharan S.K., and Tomarev S. Expression of mutated mouse myocilin induces open-angle glaucoma in transgenic mice J. Neurosci. 26 2006 11903 11914
-
(2006)
J. Neurosci.
, vol.26
, pp. 11903-11914
-
-
Senatorov, V.1
Malyukova, I.2
Fariss, R.3
Wawrousek, E.F.4
Swaminathan, S.5
Sharan, S.K.6
Tomarev, S.7
-
12
-
-
34247475386
-
Pro370Leu mutant myocilin disturbs the endoplasm reticulum stress response and mitochondrial membrane potential in human trabecular meshwork cells
-
Wang L., Zhuo Y., Liu B., Huang S., Hou F., and Ge J. Pro370Leu mutant myocilin disturbs the endoplasm reticulum stress response and mitochondrial membrane potential in human trabecular meshwork cells Mol. Vis. 13 2007 618 625
-
(2007)
Mol. Vis.
, vol.13
, pp. 618-625
-
-
Wang, L.1
Zhuo, Y.2
Liu, B.3
Huang, S.4
Hou, F.5
Ge, J.6
-
13
-
-
0344983870
-
Accumulation of mutant myocilins in ER leads to ER stress and potential cytotoxicity in human trabecular meshwork cells
-
Joe M.K., Sohn S., Hur W., Moon Y., Choi Y.R., and Kee C. Accumulation of mutant myocilins in ER leads to ER stress and potential cytotoxicity in human trabecular meshwork cells Biochem. Biophys. Res. Commun. 312 2003 592 600
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.312
, pp. 592-600
-
-
Joe, M.K.1
Sohn, S.2
Hur, W.3
Moon, Y.4
Choi, Y.R.5
Kee, C.6
-
14
-
-
33847045670
-
Aggregated myocilin induces Russell bodies and causes apoptosis: Implications for the pathogenesis of myocilin-caused primary open-angle glaucoma
-
Yam G.H.F., Gaplovska-Kysela K., Zuber C., and Roth J. Aggregated myocilin induces Russell bodies and causes apoptosis: implications for the pathogenesis of myocilin-caused primary open-angle glaucoma Am. J. Pathol. 170 2007 100 109
-
(2007)
Am. J. Pathol.
, vol.170
, pp. 100-109
-
-
Yam, G.H.F.1
Gaplovska-Kysela, K.2
Zuber, C.3
Roth, J.4
-
15
-
-
79959806015
-
The stability of myocilin olfactomedin domain variants provides new insight into glaucoma as a protein misfolding disorder
-
Burns J.N., Turnage K.C., Walker C.A., and Lieberman R.L. The stability of myocilin olfactomedin domain variants provides new insight into glaucoma as a protein misfolding disorder Biochemistry 50 2011 5824 5833
-
(2011)
Biochemistry
, vol.50
, pp. 5824-5833
-
-
Burns, J.N.1
Turnage, K.C.2
Walker, C.A.3
Lieberman, R.L.4
-
16
-
-
56749176947
-
One step at a time: Endoplasmic reticulum-associated degradation
-
Vembar S.S., and Brodsky J.L. One step at a time: endoplasmic reticulum-associated degradation Nat. Rev. Mol. Cell Biol. 9 2008 944 957
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 944-957
-
-
Vembar, S.S.1
Brodsky, J.L.2
-
17
-
-
4644359640
-
Intracellular sequestration of hetero-oligomers formed by wild-type and glaucoma-causing myocilin mutants
-
Gobeil S., Rodrigue M.A., Moisan S., Nguyen T.D., Polansky J.R., Morissette J., and Raymond V. Intracellular sequestration of hetero-oligomers formed by wild-type and glaucoma-causing myocilin mutants Invest. Ophthalmol. Vis. Sci. 45 2004 3560 3567
-
(2004)
Invest. Ophthalmol. Vis. Sci.
, vol.45
, pp. 3560-3567
-
-
Gobeil, S.1
Rodrigue, M.A.2
Moisan, S.3
Nguyen, T.D.4
Polansky, J.R.5
Morissette, J.6
Raymond, V.7
-
18
-
-
0034020149
-
Truncations in the TIGR gene in individuals with and without primary open-angle glaucoma
-
Lam D.S., Leung Y.F., Chua J.K., Baum L., Fan D.S., Choy K.W., and Pang C.P. Truncations in the TIGR gene in individuals with and without primary open-angle glaucoma Invest. Ophthalmol. Vis. Sci. 41 2000 1386 1391
-
(2000)
Invest. Ophthalmol. Vis. Sci.
, vol.41
, pp. 1386-1391
-
-
Lam, D.S.1
Leung, Y.F.2
Chua, J.K.3
Baum, L.4
Fan, D.S.5
Choy, K.W.6
Pang, C.P.7
-
19
-
-
0034780081
-
Targeted disruption of the myocilin gene (myoc) suggests that human glaucoma-causing mutations are gain of function
-
Kim B.S., Savinova O.V., Reedy M.V., Martin J., Lun Y., and Gan L. Targeted disruption of the myocilin gene (myoc) suggests that human glaucoma-causing mutations are gain of function Mol. Cell. Biol. 21 2001 7707 7713
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 7707-7713
-
-
Kim, B.S.1
Savinova, O.V.2
Reedy, M.V.3
Martin, J.4
Lun, Y.5
Gan, L.6
-
20
-
-
77952847409
-
Rescue of glaucoma-causing mutant myocilin thermal stability by chemical chaperones
-
Burns J.N., Orwig S.D., Harris J.L., Watkins J.D., Vollrath D., and Lieberman R.L. Rescue of glaucoma-causing mutant myocilin thermal stability by chemical chaperones ACS Chem. Biol. 5 2010 477 487
-
(2010)
ACS Chem. Biol.
, vol.5
, pp. 477-487
-
-
Burns, J.N.1
Orwig, S.D.2
Harris, J.L.3
Watkins, J.D.4
Vollrath, D.5
Lieberman, R.L.6
-
21
-
-
34248376062
-
Sodium 4-phenylbutyrate acts as a chemical chaperone on misfolded myocilin to rescue cells from endoplasmic reticulum stress and apoptosis
-
Yam G.H.F., Gaplovska-Kysela K., Zuber C., and Roth J. Sodium 4-phenylbutyrate acts as a chemical chaperone on misfolded myocilin to rescue cells from endoplasmic reticulum stress and apoptosis Invest. Ophthalmol. Vis. Sci. 48 2007 1683 1690
-
(2007)
Invest. Ophthalmol. Vis. Sci.
, vol.48
, pp. 1683-1690
-
-
Yam, G.H.F.1
Gaplovska-Kysela, K.2
Zuber, C.3
Roth, J.4
-
22
-
-
68349098938
-
Correction of the disease phenotype of myocilin-causing glaucoma by a natural osmolyte
-
Jia L.Y., Gong B., Pang C.P., Huang Y., Lam D.S.C., Wang N., and Yam G.H.F. Correction of the disease phenotype of myocilin-causing glaucoma by a natural osmolyte Invest. Ophthalmol. Vis. Sci. 50 2009 3743 3749
-
(2009)
Invest. Ophthalmol. Vis. Sci.
, vol.50
, pp. 3743-3749
-
-
Jia, L.Y.1
Gong, B.2
Pang, C.P.3
Huang, Y.4
Lam, D.S.C.5
Wang, N.6
Yam, G.H.F.7
-
23
-
-
80052384258
-
Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma
-
Zode G.S., Kuehn M.H., Nishimura D.Y., Searby C.C., Mohan K., and Grozdanic S.D. Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma J. Clin. Invest. 121 2011 3542 3553
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 3542-3553
-
-
Zode, G.S.1
Kuehn, M.H.2
Nishimura, D.Y.3
Searby, C.C.4
Mohan, K.5
Grozdanic, S.D.6
-
24
-
-
69149095205
-
Three susceptible loci associated with primary open-angle glaucoma identified by genome-wide association study in a Japanese population
-
Nakano M., Ikeda Y., Taniguchi T., Yagi T., Fuwa M., and Omi N. Three susceptible loci associated with primary open-angle glaucoma identified by genome-wide association study in a Japanese population Proc. Natl Acad. Sci. USA 106 2009 12838 12842
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 12838-12842
-
-
Nakano, M.1
Ikeda, Y.2
Taniguchi, T.3
Yagi, T.4
Fuwa, M.5
Omi, N.6
-
25
-
-
0033036990
-
Effects of glucocorticoids on the trabecular meshwork: Towards a better understanding of glaucoma
-
Wordinger R.J., and Clark A.F. Effects of glucocorticoids on the trabecular meshwork: towards a better understanding of glaucoma Prog. Retinal Eye Res. 18 1999 629 667
-
(1999)
Prog. Retinal Eye Res.
, vol.18
, pp. 629-667
-
-
Wordinger, R.J.1
Clark, A.F.2
-
26
-
-
17644433309
-
Cellular pharmacology and molecular biology of the trabecular meshwork inducible glucocorticoid response gene product
-
Polansky J.R., Fauss D.J., Chen P., Chen H., Lutjen-Drecoll E., and Johnson D. Cellular pharmacology and molecular biology of the trabecular meshwork inducible glucocorticoid response gene product Ophthalmologica 211 1997 126 139
-
(1997)
Ophthalmologica
, vol.211
, pp. 126-139
-
-
Polansky, J.R.1
Fauss, D.J.2
Chen, P.3
Chen, H.4
Lutjen-Drecoll, E.5
Johnson, D.6
-
27
-
-
62649096850
-
Overexpression of myocilin in the Drosophila eye activates the unfolded protein response: Implications for glaucoma
-
Carbone M.A., Ayroles J.F., Yamamoto A., Morozova T.V., West S.A., and Magwire M.M. Overexpression of myocilin in the Drosophila eye activates the unfolded protein response: implications for glaucoma PLoS ONE 4 2009 e4216
-
(2009)
PLoS ONE
, vol.4
, pp. 4216
-
-
Carbone, M.A.1
Ayroles, J.F.2
Yamamoto, A.3
Morozova, T.V.4
West, S.A.5
Magwire, M.M.6
-
28
-
-
64249160110
-
Current aspects of aqueous humor dynamics and glaucoma
-
Tamm E.R., and Ethier C.R. Current aspects of aqueous humor dynamics and glaucoma Exp. Eye Res. 88 2009 618 619
-
(2009)
Exp. Eye Res.
, vol.88
, pp. 618-619
-
-
Tamm, E.R.1
Ethier, C.R.2
-
29
-
-
14444283397
-
Identification of a gene that causes primary open angle glaucoma
-
Stone E.M., Fingert J.H., Alward W.L., Nguyen T.D., Polansky J.R., and Sunden S.L. Identification of a gene that causes primary open angle glaucoma Science 275 1997 668 670
-
(1997)
Science
, vol.275
, pp. 668-670
-
-
Stone, E.M.1
Fingert, J.H.2
Alward, W.L.3
Nguyen, T.D.4
Polansky, J.R.5
Sunden, S.L.6
-
30
-
-
0033829572
-
Age-dependent prevalence of mutations at the GLC1A locus in primary open-angle glaucoma
-
Shimizu S., Lichter P.R., Johnson A.T., Zhou Z., Higashi M., and Gottfredsdottir M. Age-dependent prevalence of mutations at the GLC1A locus in primary open-angle glaucoma Am. J. Ophthalmol. 130 2000 165 177
-
(2000)
Am. J. Ophthalmol.
, vol.130
, pp. 165-177
-
-
Shimizu, S.1
Lichter, P.R.2
Johnson, A.T.3
Zhou, Z.4
Higashi, M.5
Gottfredsdottir, M.6
-
31
-
-
79551529083
-
Biophysical characterization of the olfactomedin domain of myocilin, an extracellular matrix protein implicated in inherited forms of glaucoma
-
Orwig S.D., and Lieberman R.L. Biophysical characterization of the olfactomedin domain of myocilin, an extracellular matrix protein implicated in inherited forms of glaucoma PLoS ONE 6 2011 e16347
-
(2011)
PLoS ONE
, vol.6
, pp. 16347
-
-
Orwig, S.D.1
Lieberman, R.L.2
-
32
-
-
77649240855
-
Identifying the amylome, proteins capable of forming amyloid-like fibrils
-
Goldschmidt L., Teng P.K., Riek R., and Eisenberg D. Identifying the amylome, proteins capable of forming amyloid-like fibrils Proc. Natl Acad. Sci. USA 107 2010 3487 3492
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 3487-3492
-
-
Goldschmidt, L.1
Teng, P.K.2
Riek, R.3
Eisenberg, D.4
-
33
-
-
0032849874
-
Quantification of beta-sheet amyloid fibril structures with thioflavin T
-
LeVine H. III Quantification of beta-sheet amyloid fibril structures with thioflavin T Methods Enzymol. 309 1999 274 284
-
(1999)
Methods Enzymol.
, vol.309
, pp. 274-284
-
-
Levine Iii, H.1
-
34
-
-
0038219626
-
Domain organization and structure-function relationship of the HET-s prion protein of Podospora anserina
-
Balguerie A., Dos Reis S., Ritter C., Chaignepain S., Coulary-Salin B., and Forge V. Domain organization and structure-function relationship of the HET-s prion protein of Podospora anserina EMBO J. 22 2003 2071 2081
-
(2003)
EMBO J.
, vol.22
, pp. 2071-2081
-
-
Balguerie, A.1
Dos Reis, S.2
Ritter, C.3
Chaignepain, S.4
Coulary-Salin, B.5
Forge, V.6
-
35
-
-
0025944507
-
Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy
-
Caughey B.W., Dong A., Bhat K.S., Ernst D., Hayes S.F., and Caughey W.S. Secondary structure analysis of the scrapie-associated protein PrP 27-30 in water by infrared spectroscopy Biochemistry 30 1991 7672 7680
-
(1991)
Biochemistry
, vol.30
, pp. 7672-7680
-
-
Caughey, B.W.1
Dong, A.2
Bhat, K.S.3
Ernst, D.4
Hayes, S.F.5
Caughey, W.S.6
-
36
-
-
0014098295
-
High-resolution electron microscopic analysis of the amyloid fibril
-
Shirahama T., and Cohen A.S. High-resolution electron microscopic analysis of the amyloid fibril J. Cell Biol. 33 1967 679 708
-
(1967)
J. Cell Biol.
, vol.33
, pp. 679-708
-
-
Shirahama, T.1
Cohen, A.S.2
-
37
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
Hardy J., and Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics Science 297 2002 353 356
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
38
-
-
0033520461
-
Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates
-
Walsh D.M., Hartley D.M., Kusumoto Y., Fezoui Y., Condron M.M., and Lomakin A. Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates J. Biol. Chem. 274 1999 25945 25952
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 25945-25952
-
-
Walsh, D.M.1
Hartley, D.M.2
Kusumoto, Y.3
Fezoui, Y.4
Condron, M.M.5
Lomakin, A.6
-
39
-
-
0037130174
-
Neurodegenerative disease: Amyloid pores from pathogenic mutations
-
Lashuel H.A., Hartley D., Petre B.M., Walz T., and Lansbury P.T. Jr. Neurodegenerative disease: amyloid pores from pathogenic mutations Nature 418 2002 291
-
(2002)
Nature
, vol.418
, pp. 291
-
-
Lashuel, H.A.1
Hartley, D.2
Petre, B.M.3
Walz, T.4
Lansbury, Jr.P.T.5
-
40
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis
-
Kayed R., Head E., Thompson J.L., McIntire T.M., Milton S.C., Cotman C.W., and Glabe C.G. Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis Science 300 2003 486 489
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
McIntire, T.M.4
Milton, S.C.5
Cotman, C.W.6
Glabe, C.G.7
-
41
-
-
0032787876
-
Escherichia coli maltose-binding protein is uncommonly effective at promoting the solubility of polypeptides to which it is fused
-
Kapust R.B., and Waugh D.S. Escherichia coli maltose-binding protein is uncommonly effective at promoting the solubility of polypeptides to which it is fused Protein Sci. 8 1999 1668 1674
-
(1999)
Protein Sci.
, vol.8
, pp. 1668-1674
-
-
Kapust, R.B.1
Waugh, D.S.2
-
42
-
-
0031030202
-
Thermodynamics of maltose binding protein unfolding
-
Novokhatny V., and Ingham K. Thermodynamics of maltose binding protein unfolding Protein Sci. 6 1997 141 146
-
(1997)
Protein Sci.
, vol.6
, pp. 141-146
-
-
Novokhatny, V.1
Ingham, K.2
-
43
-
-
0034913646
-
Reversible formation of on-pathway macroscopic aggregates during the folding of maltose binding protein
-
Ganesh C., Zaidi F.N., Udgaonkar J.B., and Varadarajan R. Reversible formation of on-pathway macroscopic aggregates during the folding of maltose binding protein Protein Sci. 10 2001 1635 1644
-
(2001)
Protein Sci.
, vol.10
, pp. 1635-1644
-
-
Ganesh, C.1
Zaidi, F.N.2
Udgaonkar, J.B.3
Varadarajan, R.4
-
45
-
-
0025826915
-
Kinetic analysis of amyloid fibril polymerization in vitro
-
Naiki H., Higuchi K., Nakakuki K., and Takeda T. Kinetic analysis of amyloid fibril polymerization in vitro Lab. Invest. 65 1991 104 110
-
(1991)
Lab. Invest.
, vol.65
, pp. 104-110
-
-
Naiki, H.1
Higuchi, K.2
Nakakuki, K.3
Takeda, T.4
-
46
-
-
0030030956
-
First-order kinetic model of Alzheimer's beta-amyloid fibril extension in vitro
-
Naiki H., and Nakakuki K. First-order kinetic model of Alzheimer's beta-amyloid fibril extension in vitro Lab. Invest. 74 1996 374 383
-
(1996)
Lab. Invest.
, vol.74
, pp. 374-383
-
-
Naiki, H.1
Nakakuki, K.2
-
47
-
-
4644335370
-
Low concentrations of sodium dodecyl sulfate induce the extension of beta 2-microglobulin-related amyloid fibrils at a neutral pH
-
Yamamoto S., Hasegawa K., Yamaguchi I., Tsutsumi S., Kardos J., and Goto Y. Low concentrations of sodium dodecyl sulfate induce the extension of beta 2-microglobulin-related amyloid fibrils at a neutral pH Biochemistry 43 2004 11075 11082
-
(2004)
Biochemistry
, vol.43
, pp. 11075-11082
-
-
Yamamoto, S.1
Hasegawa, K.2
Yamaguchi, I.3
Tsutsumi, S.4
Kardos, J.5
Goto, Y.6
-
48
-
-
77954758860
-
SDS-induced fibrillation of alpha-synuclein: An alternative fibrillation pathway
-
Giehm L., Oliveira C.L., Christiansen G., Pedersen J.S., and Otzen D.E. SDS-induced fibrillation of alpha-synuclein: an alternative fibrillation pathway J. Mol. Biol. 401 2010 115 133
-
(2010)
J. Mol. Biol.
, vol.401
, pp. 115-133
-
-
Giehm, L.1
Oliveira, C.L.2
Christiansen, G.3
Pedersen, J.S.4
Otzen, D.E.5
-
49
-
-
0345306656
-
Rapid anionic micelle-mediated alpha-synuclein fibrillization in vitro
-
Necula M., Chirita C.N., and Kuret J. Rapid anionic micelle-mediated alpha-synuclein fibrillization in vitro J. Biol. Chem. 278 2003 46674 46680
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 46674-46680
-
-
Necula, M.1
Chirita, C.N.2
Kuret, J.3
-
50
-
-
0034646391
-
Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid
-
Conway K.A., Harper J.D., and Lansbury P.T. Jr Fibrils formed in vitro from alpha-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid Biochemistry 39 2000 2552 2563
-
(2000)
Biochemistry
, vol.39
, pp. 2552-2563
-
-
Conway, K.A.1
Harper, J.D.2
Lansbury, Jr.P.T.3
-
51
-
-
0035804936
-
Identification of a novel human islet amyloid polypeptide beta-sheet domain and factors influencing fibrillogenesis
-
Jaikaran E.T., Higham C.E., Serpell L.C., Zurdo J., Gross M., Clark A., and Fraser P.E. Identification of a novel human islet amyloid polypeptide beta-sheet domain and factors influencing fibrillogenesis J. Mol. Biol. 308 2001 515 525
-
(2001)
J. Mol. Biol.
, vol.308
, pp. 515-525
-
-
Jaikaran, E.T.1
Higham, C.E.2
Serpell, L.C.3
Zurdo, J.4
Gross, M.5
Clark, A.6
Fraser, P.E.7
-
52
-
-
67649201148
-
Gene-environment interactions in ocular diseases
-
Sacca S.C., Bolognesi C., Battistella A., Bagnis A., and Izzotti A. Gene-environment interactions in ocular diseases Mutat. Res. 667 2009 98 117
-
(2009)
Mutat. Res.
, vol.667
, pp. 98-117
-
-
Sacca, S.C.1
Bolognesi, C.2
Battistella, A.3
Bagnis, A.4
Izzotti, A.5
-
53
-
-
77950804863
-
Oxidative stress markers in patients with primary open-angle glaucoma
-
Ghanem A.A., Arafa L.F., and El-Baz A. Oxidative stress markers in patients with primary open-angle glaucoma Curr. Eye Res. 35 2010 295 301
-
(2010)
Curr. Eye Res.
, vol.35
, pp. 295-301
-
-
Ghanem, A.A.1
Arafa, L.F.2
El-Baz, A.3
-
55
-
-
33745615836
-
Purification and analysis of prion and amyloid aggregates
-
Kushnirov V.V., Alexandrov I.M., Mitkevich O.V., Shkundina I.S., and Ter-Avanesyan M.D. Purification and analysis of prion and amyloid aggregates Methods 39 2006 50 55
-
(2006)
Methods
, vol.39
, pp. 50-55
-
-
Kushnirov, V.V.1
Alexandrov, I.M.2
Mitkevich, O.V.3
Shkundina, I.S.4
Ter-Avanesyan, M.D.5
-
56
-
-
0033570337
-
Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons
-
Hartley D.M., Walsh D.M., Ye C.P., Diehl T., Vasquez S., and Vassilev P.M. Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons J. Neurosci. 19 1999 8876 8884
-
(1999)
J. Neurosci.
, vol.19
, pp. 8876-8884
-
-
Hartley, D.M.1
Walsh, D.M.2
Ye, C.P.3
Diehl, T.4
Vasquez, S.5
Vassilev, P.M.6
-
57
-
-
79959887638
-
A diversity of assembly mechanisms of a generic amyloid fold
-
Eichner T., and Radford S.E. A diversity of assembly mechanisms of a generic amyloid fold Mol. Cell 43 2011 8 18
-
(2011)
Mol. Cell
, vol.43
, pp. 8-18
-
-
Eichner, T.1
Radford, S.E.2
-
58
-
-
71349083669
-
Conformational diseases: Looking into the eyes
-
Surguchev A., and Surguchov A. Conformational diseases: looking into the eyes Brain Res. Bull. 81 2010 12 24
-
(2010)
Brain Res. Bull.
, vol.81
, pp. 12-24
-
-
Surguchev, A.1
Surguchov, A.2
-
59
-
-
0036208082
-
Caspase activation and amyloid precursor protein cleavage in rat ocular hypertension
-
McKinnon S.J., Lehman D.M., Kerrigan-Baumrind L.A., Merges C.A., Pease M.E., and Kerrigan D.F. Caspase activation and amyloid precursor protein cleavage in rat ocular hypertension Invest. Ophthalmol. Vis. Sci. 43 2002 1077 1087
-
(2002)
Invest. Ophthalmol. Vis. Sci.
, vol.43
, pp. 1077-1087
-
-
McKinnon, S.J.1
Lehman, D.M.2
Kerrigan-Baumrind, L.A.3
Merges, C.A.4
Pease, M.E.5
Kerrigan, D.F.6
-
60
-
-
34548076604
-
Targeting amyloid-beta in glaucoma treatment
-
Guo L., Salt T.E., Luong V., Wood N., Cheung W., and Maass A. Targeting amyloid-beta in glaucoma treatment Proc. Natl Acad. Sci. USA 104 2007 13444 13449
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 13444-13449
-
-
Guo, L.1
Salt, T.E.2
Luong, V.3
Wood, N.4
Cheung, W.5
Maass, A.6
-
61
-
-
18044398967
-
Vitreous fluid levels of beta-amyloid((1-42)) and tau in patients with retinal diseases
-
Yoneda S., Hara H., Hirata A., Fukushima M., Inomata Y., and Tanihara H. Vitreous fluid levels of beta-amyloid((1-42)) and tau in patients with retinal diseases Jpn. J. Ophthalmol. 49 2005 106 108
-
(2005)
Jpn. J. Ophthalmol.
, vol.49
, pp. 106-108
-
-
Yoneda, S.1
Hara, H.2
Hirata, A.3
Fukushima, M.4
Inomata, Y.5
Tanihara, H.6
-
62
-
-
0037247871
-
Prion protein accumulation in eyes of patients with sporadic and variant Creutzfeldt-Jakob disease
-
Head M.W., Northcott V., Rennison K., Ritchie D., McCardle L., and Bunn T.J. Prion protein accumulation in eyes of patients with sporadic and variant Creutzfeldt-Jakob disease Invest. Ophthalmol. Vis. Sci. 44 2003 342 346
-
(2003)
Invest. Ophthalmol. Vis. Sci.
, vol.44
, pp. 342-346
-
-
Head, M.W.1
Northcott, V.2
Rennison, K.3
Ritchie, D.4
McCardle, L.5
Bunn, T.J.6
-
63
-
-
21744456373
-
Changes in aqueous humor dynamics with age and glaucoma
-
Gabelt B.A.T., and Kaufman P.L. Changes in aqueous humor dynamics with age and glaucoma Prog. Retinal Eye Res. 24 2005 612 637
-
(2005)
Prog. Retinal Eye Res.
, vol.24
, pp. 612-637
-
-
Gabelt, B.A.T.1
Kaufman, P.L.2
-
64
-
-
0037809408
-
Gene expression profile of the human trabecular meshwork: NEIBank sequence tag analysis
-
Tomarev S.I., Wistow G., Raymond V., Dubois S., and Malyukova I. Gene expression profile of the human trabecular meshwork: NEIBank sequence tag analysis Invest. Ophthalmol. Vis. Sci. 44 2003 2588 2596
-
(2003)
Invest. Ophthalmol. Vis. Sci.
, vol.44
, pp. 2588-2596
-
-
Tomarev, S.I.1
Wistow, G.2
Raymond, V.3
Dubois, S.4
Malyukova, I.5
-
65
-
-
0033807221
-
Ultrastructural localization of myocilin in human trabecular meshwork cells and tissues
-
Ueda J., Wentz-Hunter K.K., Cheng E.L., Fukuchi T., Abe H., and Yue B.Y. Ultrastructural localization of myocilin in human trabecular meshwork cells and tissues J. Histochem. Cytochem. 48 2000 1321 1330
-
(2000)
J. Histochem. Cytochem.
, vol.48
, pp. 1321-1330
-
-
Ueda, J.1
Wentz-Hunter, K.K.2
Cheng, E.L.3
Fukuchi, T.4
Abe, H.5
Yue, B.Y.6
-
66
-
-
0036202868
-
Distribution of myocilin and extracellular matrix components in the juxtacanalicular tissue of human eyes
-
Ueda J., Wentz-Hunter K., and Yue B.Y. Distribution of myocilin and extracellular matrix components in the juxtacanalicular tissue of human eyes Invest. Ophthalmol. Vis. Sci. 43 2002 1068 1076
-
(2002)
Invest. Ophthalmol. Vis. Sci.
, vol.43
, pp. 1068-1076
-
-
Ueda, J.1
Wentz-Hunter, K.2
Yue, B.Y.3
-
67
-
-
0036140397
-
In vitro localization of TIGR/MYOC in trabecular meshwork extracellular matrix and binding to fibronectin
-
Filla M.S., Liu X., Nguyen T.D., Polansky J.R., Brandt C.R., Kaufman P.L., and Peters D.M. In vitro localization of TIGR/MYOC in trabecular meshwork extracellular matrix and binding to fibronectin Invest. Ophthalmol. Vis. Sci. 43 2002 151 161
-
(2002)
Invest. Ophthalmol. Vis. Sci.
, vol.43
, pp. 151-161
-
-
Filla, M.S.1
Liu, X.2
Nguyen, T.D.3
Polansky, J.R.4
Brandt, C.R.5
Kaufman, P.L.6
Peters, D.M.7
-
68
-
-
64249161403
-
Structural changes of the trabecular meshwork in different kinds of glaucoma
-
Tektas O.Y., and Lutjen-Drecoll E. Structural changes of the trabecular meshwork in different kinds of glaucoma Exp. Eye Res. 88 2009 769 775
-
(2009)
Exp. Eye Res.
, vol.88
, pp. 769-775
-
-
Tektas, O.Y.1
Lutjen-Drecoll, E.2
-
69
-
-
33745224979
-
Collagen plays an active role in the aggregation of beta2-microglobulin under physiopathological conditions of dialysis-related amyloidosis
-
Relini A., Canale C., De Stefano S., Rolandi R., Giorgetti S., and Stoppini M. Collagen plays an active role in the aggregation of beta2-microglobulin under physiopathological conditions of dialysis-related amyloidosis J. Biol. Chem. 281 2006 16521 16529
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 16521-16529
-
-
Relini, A.1
Canale, C.2
De Stefano, S.3
Rolandi, R.4
Giorgetti, S.5
Stoppini, M.6
-
70
-
-
11144221004
-
Amyloid accomplices and enforcers
-
Alexandrescu A.T. Amyloid accomplices and enforcers Protein Sci. 14 2005 1 12
-
(2005)
Protein Sci.
, vol.14
, pp. 1-12
-
-
Alexandrescu, A.T.1
-
71
-
-
79953179308
-
Heparin binds 8 kDa gelsolin cross-beta-sheet oligomers and accelerates amyloidogenesis by hastening fibril extension
-
Solomon J.P., Bourgault S., Powers E.T., and Kelly J.W. Heparin binds 8 kDa gelsolin cross-beta-sheet oligomers and accelerates amyloidogenesis by hastening fibril extension Biochemistry 50 2011 2486 2498
-
(2011)
Biochemistry
, vol.50
, pp. 2486-2498
-
-
Solomon, J.P.1
Bourgault, S.2
Powers, E.T.3
Kelly, J.W.4
-
72
-
-
0033572813
-
Interactions of Alzheimer amyloid-beta peptides with glycosaminoglycans effects on fibril nucleation and growth
-
McLaurin J., Franklin T., Zhang X., Deng J., and Fraser P.E. Interactions of Alzheimer amyloid-beta peptides with glycosaminoglycans effects on fibril nucleation and growth Eur. J. Biochem. 266 1999 1101 1110
-
(1999)
Eur. J. Biochem.
, vol.266
, pp. 1101-1110
-
-
McLaurin, J.1
Franklin, T.2
Zhang, X.3
Deng, J.4
Fraser, P.E.5
-
73
-
-
41949084293
-
Heparin strongly enhances the formation of beta2-microglobulin amyloid fibrils in the presence of type i collagen
-
Relini A., De Stefano S., Torrassa S., Cavalleri O., Rolandi R., and Gliozzi A. Heparin strongly enhances the formation of beta2-microglobulin amyloid fibrils in the presence of type I collagen J. Biol. Chem. 283 2008 4912 4920
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 4912-4920
-
-
Relini, A.1
De Stefano, S.2
Torrassa, S.3
Cavalleri, O.4
Rolandi, R.5
Gliozzi, A.6
-
74
-
-
0035947372
-
Impairment of the ubiquitin-proteasome system by protein aggregation
-
Bence N.F., Sampat R.M., and Kopito R.R. Impairment of the ubiquitin-proteasome system by protein aggregation Science 292 2001 1552 1555
-
(2001)
Science
, vol.292
, pp. 1552-1555
-
-
Bence, N.F.1
Sampat, R.M.2
Kopito, R.R.3
-
75
-
-
0032857679
-
Identification of the region in the N-terminal domain responsible for the cytoplasmic localization of Myoc/Tigr and its association with microtubules
-
Mertts M., Garfield S., Tanemoto K., and Tomarev S.I. Identification of the region in the N-terminal domain responsible for the cytoplasmic localization of Myoc/Tigr and its association with microtubules Lab. Invest. 79 1999 1237 1245
-
(1999)
Lab. Invest.
, vol.79
, pp. 1237-1245
-
-
Mertts, M.1
Garfield, S.2
Tanemoto, K.3
Tomarev, S.I.4
-
76
-
-
78649476655
-
Aqueous humor rapidly stimulates myocilin secretion from human trabecular meshwork cells
-
Resch Z.T., Hann C.R., Cook K.A., and Fautsch M.P. Aqueous humor rapidly stimulates myocilin secretion from human trabecular meshwork cells Exp. Eye Res. 91 2010 901 908
-
(2010)
Exp. Eye Res.
, vol.91
, pp. 901-908
-
-
Resch, Z.T.1
Hann, C.R.2
Cook, K.A.3
Fautsch, M.P.4
-
77
-
-
23844447020
-
Extracellular trafficking of myocilin in human trabecular meshwork cells
-
Hardy K.M., Hoffman E.A., Gonzalez P., McKay B.S., and Stamer W.D. Extracellular trafficking of myocilin in human trabecular meshwork cells J. Biol. Chem. 280 2005 28917 28926
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 28917-28926
-
-
Hardy, K.M.1
Hoffman, E.A.2
Gonzalez, P.3
McKay, B.S.4
Stamer, W.D.5
-
78
-
-
33750453080
-
Coiled-coil targeting of myocilin to intracellular membranes
-
Stamer W., Perkumas K., and Hoffman E. Coiled-coil targeting of myocilin to intracellular membranes Exp. Eye Res. 83 2006 1386 1395
-
(2006)
Exp. Eye Res.
, vol.83
, pp. 1386-1395
-
-
Stamer, W.1
Perkumas, K.2
Hoffman, E.3
-
79
-
-
58149389723
-
Potential role of lysosomal dysfunction in the pathogenesis of primary open angle glaucoma
-
Liton P.B., Lin Y., Gonzalez P., and Epstein D.L. Potential role of lysosomal dysfunction in the pathogenesis of primary open angle glaucoma Autophagy 5 2009 122 124
-
(2009)
Autophagy
, vol.5
, pp. 122-124
-
-
Liton, P.B.1
Lin, Y.2
Gonzalez, P.3
Epstein, D.L.4
-
80
-
-
73049100386
-
Olfactomedin domain-containing proteins: Possible mechanisms of action and functions in normal development and pathology
-
Tomarev S.I., and Nakaya N. Olfactomedin domain-containing proteins: possible mechanisms of action and functions in normal development and pathology Mol. Neurobiol. 40 2009 122 138
-
(2009)
Mol. Neurobiol.
, vol.40
, pp. 122-138
-
-
Tomarev, S.I.1
Nakaya, N.2
-
81
-
-
0025988474
-
Olfactomedin: Purification, characterization, and localization of a novel olfactory glycoprotein
-
Snyder D.A., Rivers A.M., Yokoe H., Menco B.P., and Anholt R.R. Olfactomedin: purification, characterization, and localization of a novel olfactory glycoprotein Biochemistry 30 1991 9143 9153
-
(1991)
Biochemistry
, vol.30
, pp. 9143-9153
-
-
Snyder, D.A.1
Rivers, A.M.2
Yokoe, H.3
Menco, B.P.4
Anholt, R.R.5
-
82
-
-
35948954725
-
Structural features and functional domains of amassin-1, a cell-binding olfactomedin protein
-
Hillier B.J., and Vacquier V.D. Structural features and functional domains of amassin-1, a cell-binding olfactomedin protein Biochem. Cell Biol. 85 2007 552 562
-
(2007)
Biochem. Cell Biol.
, vol.85
, pp. 552-562
-
-
Hillier, B.J.1
Vacquier, V.D.2
-
83
-
-
58149328927
-
Myocilin promotes substrate adhesion, spreading and formation of focal contacts in podocytes and mesangial cells
-
Goldwich A., Scholz M., and Tamm E.R. Myocilin promotes substrate adhesion, spreading and formation of focal contacts in podocytes and mesangial cells Histochem. Cell Biol. 131 2009 167 180
-
(2009)
Histochem. Cell Biol.
, vol.131
, pp. 167-180
-
-
Goldwich, A.1
Scholz, M.2
Tamm, E.R.3
-
84
-
-
79961103406
-
Olfactomedin 4, a novel marker for the differentiation and progression of gastrointestinal cancers
-
Yu L., Wang L., and Chen S. Olfactomedin 4, a novel marker for the differentiation and progression of gastrointestinal cancers Neoplasma 58 2011 9 13
-
(2011)
Neoplasma
, vol.58
, pp. 9-13
-
-
Yu, L.1
Wang, L.2
Chen, S.3
-
85
-
-
3242887695
-
Protein structure prediction and analysis using the Robetta server
-
Kim D.E., Chivian D., and Baker D. Protein structure prediction and analysis using the Robetta server Nucleic Acids Res. 32 2004 W526 W531
-
(2004)
Nucleic Acids Res.
, vol.32
-
-
Kim, D.E.1
Chivian, D.2
Baker, D.3
-
86
-
-
79953245314
-
Amyloid structure: Conformational diversity and consequences
-
Toyama B.H., and Weissman J.S. Amyloid structure: conformational diversity and consequences Annu. Rev. Biochem. 80 2011 557 585
-
(2011)
Annu. Rev. Biochem.
, vol.80
, pp. 557-585
-
-
Toyama, B.H.1
Weissman, J.S.2
-
88
-
-
36749078792
-
Folding versus aggregation: Polypeptide conformations on competing pathways
-
Jahn T.R., and Radford S.E. Folding versus aggregation: polypeptide conformations on competing pathways Arch. Biochem. Biophys. 469 2008 100 117
-
(2008)
Arch. Biochem. Biophys.
, vol.469
, pp. 100-117
-
-
Jahn, T.R.1
Radford, S.E.2
-
89
-
-
34248679167
-
Tricine-SDS-PAGE
-
Schagger H. Tricine-SDS-PAGE Nat. Protoc. 1 2006 16 22
-
(2006)
Nat. Protoc.
, vol.1
, pp. 16-22
-
-
Schagger, H.1
-
90
-
-
0027512825
-
Ribonuclease S-peptide as a carrier in fusion proteins
-
Kim J.S., and Raines R.T. Ribonuclease S-peptide as a carrier in fusion proteins Protein Sci. 2 1993 348 356
-
(1993)
Protein Sci.
, vol.2
, pp. 348-356
-
-
Kim, J.S.1
Raines, R.T.2
|