Hedgehog-GLI signaling inhibition suppresses tumor growth in squamous lung cancer

Clinical Cancer Research

Volumn 20, Issue 6, 2014, Pages 1566-1575

  Huang, Lingling ^a   Walter, Vonn ^b   Hayes, D Neil ^b   Onaitis, Mark ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; GANT 61; SHORT HAIRPIN RNA; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; UNCLASSIFIED DRUG; VISMODEGIB; G PROTEIN COUPLED RECEPTOR; GLI1 PROTEIN, HUMAN; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; SMO PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CANCER SURVIVAL; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; FEASIBILITY STUDY; GENE DELETION; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG SQUAMOUS CELL CARCINOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SMOOTHENED GENE; ANIMAL; DRUG EFFECTS; GENE SILENCING; LUNG TUMOR; METABOLISM; PATHOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; WESTERN BLOTTING; XENOGRAFT;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; GENE KNOCKDOWN TECHNIQUES; HEDGEHOG PROTEINS; HETEROGRAFTS; HUMANS; LUNG NEOPLASMS; MICE; PYRIDINES; PYRIMIDINES; RECEPTORS, G-PROTEIN-COUPLED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84896538817     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-13-2195     Document Type: Article

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