Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E

Nature

Volumn 417, Issue 6886, 2002, Pages 299-304

  Duman Scheel, Molly ^a   Weng, Li ^a   Xin, Shiljie ^a   Du, Wei ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; MUTAGENS; TUMORS;

CELL GROWTH;

CELLS;

CYCLIN D; CYCLIN E; RETINOBLASTOMA PROTEIN;

CANCER;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CELL CYCLE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DROSOPHILA; GENE OVEREXPRESSION; GENETIC SCREENING; GENETIC TRANSCRIPTION; GROWTH REGULATION; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; RETINOBLASTOMA; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANIMALS; BROMODEOXYURIDINE; CELL DIVISION; CYCLIN E; CYCLINS; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EYE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INSECT PROTEINS; MEMBRANE PROTEINS; PROMOTER REGIONS (GENETICS); RECEPTORS, CELL SURFACE; RETINOBLASTOMA PROTEIN; S PHASE; TRANSCRIPTION FACTORS;

ANIMALIA; ERINACEIDAE;

EID: 0037118056     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/417299a     Document Type: Article

References (30)

1. Gli proteins and Hedgehog signaling: Development and cancer
2. The retinoblastoma protein and cell cycle control
3. The regulation of E2F by pRB-family proteins
4. The role of RBF in developmentally regulated cell proliferation in the eye disc and in Cyclin D/Cdk4 induced cellular growth
5. More surprises in the Hedgehog signaling pathway
6. Signals transmitted along retinal axons in Drosophila: Hedgehog signal reception and the cell circuitry of lamina cartridge assembly
7. Isolation of Drosophila cyclin D, a protein expressed in the morphogenetic furrow before entry into S phase
8. Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation
9. Where the cell cycle and histones meet
10. Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development
11. A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis
12. Tissue-specific regulation of cyclin E transcription during Drosophila melanogaster embryogenesis
13. Zinc fingers in sex determination: Only one of the two C. elegans Tra-1 proteins binds DNA in vitro
14. Analysis of a Drosophila cyclin E hypomorphic mutation suggests a novel role for cyclin E in cell proliferation control during eye imaginal disc development
15. Genetic control of cell size
16. Coordination of growth and cell division in the Drosophila wing
17. The Drosophila cyclinD-cdk4 complex promotes cellular growth
18. Drosophila cdk4 is required for normal growth and is dispensable for cell cycle progression
19. patched overexpression alters wing disc size and pattern: Transcriptional and post-transcriptional effects on hedgehog targets
20. Sonic hedgehog promotes G(1) cyclin expression and sustained cell cycle progression in mammalian neuronal precursors
21. Mouse patched1 controls body size determination and limb patterning
22. Mice lacking cyclin D1 are small and show defects in eye and mammary gland development
23. Cyclin E in human cancers
24. Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice
25. Analysis of genetic mosaics in developing and adult Drosophila tissues
26. Organizing activity of wingless protein in Drosophila
27. DNA replication control through interaction of E2F-RB and the origin recognition complex
28. Wingless and Notch regulate cell-cycle arrest in the developing Drosophila wing