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Volumn 131, Issue , 2014, Pages 77-85

Biomonitoring exposure assessment to contemporary pesticides in a school children population of Spain

Author keywords

Children; Exposure; Metabolites; Pesticides; Urine

Indexed keywords

2 HYDROXY 3,5,6 TRICHLORPYRIDINE; 4 HYDROXY 2 ISOPROPYL 6 METHYLPYRIMIDINE; 4 NITROPHENOL; CHLORPYRIFOS; CREATININE; DIMETHOATE; DIMPYLATE; FOLPET; HERBICIDE; ORGANOPHOSPHATE INSECTICIDE; PARATHION; PARATHION METHYL; PESTICIDE; PHOSPHATE; PYRETHROID; UNCLASSIFIED DRUG;

EID: 84896518350     PISSN: 00139351     EISSN: 10960953     Source Type: Journal    
DOI: 10.1016/j.envres.2014.02.009     Document Type: Article
Times cited : (89)

References (65)
  • 1
    • 84896501997 scopus 로고    scopus 로고
    • AEPLA (Asociación Empresarial para la Protección de las Plantas), 2010. Memoria AEPLA
    • AEPLA (Asociación Empresarial para la Protección de las Plantas), 2010. Memoria AEPLA 2009. http://www.aepla.es/publicaciones.
    • (2009)
  • 2
    • 84896510011 scopus 로고    scopus 로고
    • Agriculture Department (Conselleria de Presidencia, Agricultura, Pesca y Alimentación de la Generalitat Valenciana, Spain), 2010. Informe del sector agrario
    • Agriculture Department (Conselleria de Presidencia, Agricultura, Pesca y Alimentación de la Generalitat Valenciana, Spain), 2010. Informe del sector agrario 2010. http://www.agricultura.gva.es/web/.
    • (2010)
  • 3
    • 84896525924 scopus 로고    scopus 로고
    • Agriculture Department (Conselleria de Agricultura, Pesca y Alimentación de la Generalitat Valenciana, Spain), 2012. Boltetín de avisos agrarios. Residuos de plaguicidas en cítricos.
    • Agriculture Department (Conselleria de Agricultura, Pesca y Alimentación de la Generalitat Valenciana, Spain), 2012. Boltetín de avisos agrarios. Residuos de plaguicidas en cítricos. http://www.agricultura.gva.es/web/.
  • 8
    • 84872271689 scopus 로고    scopus 로고
    • Multiresidue determination of 375 organic contaminants including pesticides, polychlorinated biphenyls and polyaromatic hydrocarbons in fruits and vegetables by gas chromatography-triple quadrupole mass spectrometry with introduction of semi-quantification approach
    • Banerjee K., Utture S., Dasgupta S., Kandaswamy C., Pradhan S., Kulkarni S., Adsule P. Multiresidue determination of 375 organic contaminants including pesticides, polychlorinated biphenyls and polyaromatic hydrocarbons in fruits and vegetables by gas chromatography-triple quadrupole mass spectrometry with introduction of semi-quantification approach. J. Chromatogr. a 2012, 1270:283-295.
    • (2012) J. Chromatogr. a , vol.1270 , pp. 283-295
    • Banerjee, K.1    Utture, S.2    Dasgupta, S.3    Kandaswamy, C.4    Pradhan, S.5    Kulkarni, S.6    Adsule, P.7
  • 9
    • 84896498720 scopus 로고    scopus 로고
    • Urinary concentrations of pyrethroid metabolites in the general US population, NHANES 1999-2002
    • Barr D.B., Baker S.E., Whitehead R.D., Wong L., Needham L.L. Urinary concentrations of pyrethroid metabolites in the general US population, NHANES 1999-2002. Epidemiology 2008, 19:S192-S193.
    • (2008) Epidemiology , vol.19
    • Barr, D.B.1    Baker, S.E.2    Whitehead, R.D.3    Wong, L.4    Needham, L.L.5
  • 14
    • 67649646769 scopus 로고    scopus 로고
    • Surveillance of pesticide residues in fruits from Valencia during twenty months (2004/05)
    • Berrada H., Fernandez M., Ruiz M.J., Molto J.C., Manes J., Font G. Surveillance of pesticide residues in fruits from Valencia during twenty months (2004/05). Food Control 2010, 21:36-44.
    • (2010) Food Control , vol.21 , pp. 36-44
    • Berrada, H.1    Fernandez, M.2    Ruiz, M.J.3    Molto, J.C.4    Manes, J.5    Font, G.6
  • 15
    • 0038103609 scopus 로고    scopus 로고
    • Genotoxicity of pesticides: a review of human biomonitoring studies
    • Bolognesi C. Genotoxicity of pesticides: a review of human biomonitoring studies. Mutat. Res. - Rev. Mutat. Res. 2003, 543:251-272.
    • (2003) Mutat. Res. - Rev. Mutat. Res. , vol.543 , pp. 251-272
    • Bolognesi, C.1
  • 16
    • 77953050444 scopus 로고    scopus 로고
    • Attention-deficit/hyperactivity disorder and urinary metabolites of organophosphate pesticides
    • Bouchard M.F., Bellinger D.C., Wright R.O., Weisskopf M.G. Attention-deficit/hyperactivity disorder and urinary metabolites of organophosphate pesticides. Pediatrics 2010, 125:270-277.
    • (2010) Pediatrics , vol.125 , pp. 270-277
    • Bouchard, M.F.1    Bellinger, D.C.2    Wright, R.O.3    Weisskopf, M.G.4
  • 18
    • 0023947896 scopus 로고
    • Statistics in Medicine: calculating confidence intervals for some non-parametric analysis
    • Campbell M.J., Garner M.J. Statistics in Medicine: calculating confidence intervals for some non-parametric analysis. Br. Med. J. 1988, 296:1454-1456.
    • (1988) Br. Med. J. , vol.296 , pp. 1454-1456
    • Campbell, M.J.1    Garner, M.J.2
  • 20
    • 84856477196 scopus 로고    scopus 로고
    • Center for Disease Control and Prevention (CDC)
    • National Health and Nutrition Examination Survey Data. U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Hyattsville, MD. Available:
    • Center for Disease Control and Prevention (CDC), 2009. National Health and Nutrition Examination Survey Data. U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, Hyattsville, MD. Available: http://www.cdc.gov/nchs/about/major/nhanes/datalink.htm.
    • (2009)
  • 23
    • 84879270048 scopus 로고    scopus 로고
    • LC-MS characterization of contemporary pesticides in PM10 of Valencia Region, Spain
    • Coscollá C., Hart E., Pastor A., Yusa V. LC-MS characterization of contemporary pesticides in PM10 of Valencia Region, Spain. Atmos. Environ. 2013, 77:394-403.
    • (2013) Atmos. Environ. , vol.77 , pp. 394-403
    • Coscollá, C.1    Hart, E.2    Pastor, A.3    Yusa, V.4
  • 26
    • 84878374183 scopus 로고    scopus 로고
    • Pesticide occurrence and aquatic benchmark exceedances in urban surface waters and sediments in three urban areas of California, USA, 2008-2011
    • Ensminger M.P., Budd R., Kelley K.C., Goh K.S. Pesticide occurrence and aquatic benchmark exceedances in urban surface waters and sediments in three urban areas of California, USA, 2008-2011. Environ. Monit. Assess. 2013, 185:3697-3710.
    • (2013) Environ. Monit. Assess. , vol.185 , pp. 3697-3710
    • Ensminger, M.P.1    Budd, R.2    Kelley, K.C.3    Goh, K.S.4
  • 27
    • 84896511602 scopus 로고    scopus 로고
    • ESBIO, 2004. Expert Team to Support Biomonitoring in Europe protocol for sample collection in biomonitoring programs in Europe.
    • ESBIO, 2004. Expert Team to Support Biomonitoring in Europe protocol for sample collection in biomonitoring programs in Europe. http://www.eu-humanbiomonitoring.org/sub/esbio.htm.
  • 28
    • 58349115177 scopus 로고    scopus 로고
    • Non-invasive matrices in human biomonitoring: a review
    • Esteban M., Castano A. Non-invasive matrices in human biomonitoring: a review. Environ. Int. 2009, 35:438-449.
    • (2009) Environ. Int. , vol.35 , pp. 438-449
    • Esteban, M.1    Castano, A.2
  • 29
    • 84896503665 scopus 로고    scopus 로고
    • European Commission, 2001. Commission decision 2001/520/EC concerning the non-inclusion of parathion in Annex I to Council Directive 91/414/EEC and the withdrawal of authorisations for plant protection products containing this active substance, Brussels, Belgium, 2001. Official Journal of the European Communities, L 148 of 9 July
    • European Commission, 2001. Commission decision 2001/520/EC concerning the non-inclusion of parathion in Annex I to Council Directive 91/414/EEC and the withdrawal of authorisations for plant protection products containing this active substance, Brussels, Belgium, 2001. Official Journal of the European Communities, L 148 of 9 July 2001.
    • (2001)
  • 30
    • 84896541337 scopus 로고    scopus 로고
    • European Commission, 2002. Commission decision 2002/657/EC concerning the implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretation of results, Brussels, Belgium, 2002. Official Journal of the European Communities, L221 of 12 August
    • European Commission, 2002. Commission decision 2002/657/EC concerning the implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretation of results, Brussels, Belgium, 2002. Official Journal of the European Communities, L221 of 12 August 2002.
    • (2002)
  • 31
    • 84896523294 scopus 로고    scopus 로고
    • European Commission, 2007. Commission decision 2007/393/EC concerning the non-inclusion of diazinon in Annex I to Council Directive 91/414/EEC and the withdrawal of authorisations for plant protection products containing that substance, Brussels, Belgium, 2007. Official Journal of the European Communities, L 148 of 6 June
    • European Commission, 2007. Commission decision 2007/393/EC concerning the non-inclusion of diazinon in Annex I to Council Directive 91/414/EEC and the withdrawal of authorisations for plant protection products containing that substance, Brussels, Belgium, 2007. Official Journal of the European Communities, L 148 of 6 June 2007.
    • (2007)
  • 32
    • 85078367191 scopus 로고    scopus 로고
    • European Food Safety Authority, 2013. The 2010 European Union report on pesticide residues in food. Journal 11, 3130, 10.2903/j.efsa.2013.3130. Online:
    • European Food Safety Authority, 2013. The 2010 European Union report on pesticide residues in food. Journal 11, 3130 (808 pp.) 10.2903/j.efsa.2013.3130. Online: http://www.efsa.europa.eu/efsajournal.
  • 34
    • 84865810812 scopus 로고    scopus 로고
    • GC-MS characterization of contemporary pesticides in PM10 of Valencia Region, Spain
    • Hart E., Coscolla C., Pastor A., Yusa V. GC-MS characterization of contemporary pesticides in PM10 of Valencia Region, Spain. Atmos. Environ. 2012, 62:118-129.
    • (2012) Atmos. Environ. , vol.62 , pp. 118-129
    • Hart, E.1    Coscolla, C.2    Pastor, A.3    Yusa, V.4
  • 35
    • 65649128629 scopus 로고    scopus 로고
    • Using Biomonitoring Equivalents to interpret human biomonitoring data in a public health risk context
    • Hays S.M., Aylward L.L. Using Biomonitoring Equivalents to interpret human biomonitoring data in a public health risk context. J. Appl. Toxicol. 2009, 29:275-288.
    • (2009) J. Appl. Toxicol. , vol.29 , pp. 275-288
    • Hays, S.M.1    Aylward, L.L.2
  • 36
    • 84896522317 scopus 로고    scopus 로고
    • Health Canada, 2009. Report on Human Biomonitoring of Environmental Chemicals in Canada: results of the Canadian Health Measures Survey Cycle 1 (2007-2009). Available from:
    • Health Canada, 2009. Report on Human Biomonitoring of Environmental Chemicals in Canada: results of the Canadian Health Measures Survey Cycle 1 (2007-2009). Available from: http://www.hc-sc.gc.ca/ewh-semt/pubs/contaminants/chmsecms/index-eng.php.
  • 38
    • 84860236060 scopus 로고    scopus 로고
    • The atlas of dialkylphosphates; assessment of cumulative human organophosphorus pesticides[U+05F3] exposure
    • Kavvalakis M.P., Tsatsakis A.M. The atlas of dialkylphosphates; assessment of cumulative human organophosphorus pesticides[U+05F3] exposure. Forensic Sci. Int. 2012, 218:111-122.
    • (2012) Forensic Sci. Int. , vol.218 , pp. 111-122
    • Kavvalakis, M.P.1    Tsatsakis, A.M.2
  • 39
    • 84859157566 scopus 로고    scopus 로고
    • Systematic review of biomonitoring studies to determine the association between exposure to organophosphorus and pyrethroid insecticides and human health outcomes
    • Koureas M., Tsakalof A., Tsatsakis A., Hadjichristodoulou C. Systematic review of biomonitoring studies to determine the association between exposure to organophosphorus and pyrethroid insecticides and human health outcomes. Toxicol. Lett. 2012, 210:155-168.
    • (2012) Toxicol. Lett. , vol.210 , pp. 155-168
    • Koureas, M.1    Tsakalof, A.2    Tsatsakis, A.3    Hadjichristodoulou, C.4
  • 40
    • 3042756741 scopus 로고    scopus 로고
    • A pilot study on the determination of perfluorooctanesulfonate and other perfluorinated compounds in blood of Canadians
    • Kubwabo C., Vais N., Benoit F.M. A pilot study on the determination of perfluorooctanesulfonate and other perfluorinated compounds in blood of Canadians. J. Environ. Monit. 2004, 6:540-545.
    • (2004) J. Environ. Monit. , vol.6 , pp. 540-545
    • Kubwabo, C.1    Vais, N.2    Benoit, F.M.3
  • 41
    • 0015409598 scopus 로고
    • Creatinine assay by a reaction-kinetic principle
    • Larsen K. Creatinine assay by a reaction-kinetic principle. Clin. Chim. Acta 1972, 41:209-217.
    • (1972) Clin. Chim. Acta , vol.41 , pp. 209-217
    • Larsen, K.1
  • 42
    • 84859157087 scopus 로고    scopus 로고
    • Simultaneous determination of five synthetic pyrethroid metabolites in urine by liquid chromatography-tandem mass spectrometry: application to 39 persons without known exposure to pyrethroids
    • Le Grand R., Dulaurent S., Gaulier J.M., Saint-Marcoux F., Moesch C., Lachatre G. Simultaneous determination of five synthetic pyrethroid metabolites in urine by liquid chromatography-tandem mass spectrometry: application to 39 persons without known exposure to pyrethroids. Toxicol. Lett. 2012, 210:248-253.
    • (2012) Toxicol. Lett. , vol.210 , pp. 248-253
    • Le Grand, R.1    Dulaurent, S.2    Gaulier, J.M.3    Saint-Marcoux, F.4    Moesch, C.5    Lachatre, G.6
  • 44
    • 80052599016 scopus 로고    scopus 로고
    • Determination of pyrethroid metabolites in human urine using liquid phase microextraction coupled in-syringe derivatization followed by gas chromatography/electron capture detection
    • Lin C.H., Yan C.T., Kumar P.V., Li H.P., Jen J.F. Determination of pyrethroid metabolites in human urine using liquid phase microextraction coupled in-syringe derivatization followed by gas chromatography/electron capture detection. Anal. Bioanal. Chem. 2011, 401:927-937.
    • (2011) Anal. Bioanal. Chem. , vol.401 , pp. 927-937
    • Lin, C.H.1    Yan, C.T.2    Kumar, P.V.3    Li, H.P.4    Jen, J.F.5
  • 46
    • 84872150581 scopus 로고    scopus 로고
    • Combined use of liquid chromatography triple quadrupole mass spectrometry and liquid chromatography quadrupole time-of-flight mass spectrometry in systematic screening of pesticides and other contaminants in water samples
    • Masia A., Ibanez M., Blasco C., Sancho J.V., Pico Y., Hernandez F. Combined use of liquid chromatography triple quadrupole mass spectrometry and liquid chromatography quadrupole time-of-flight mass spectrometry in systematic screening of pesticides and other contaminants in water samples. Anal. Chim. Acta 2013, 761:117-127.
    • (2013) Anal. Chim. Acta , vol.761 , pp. 117-127
    • Masia, A.1    Ibanez, M.2    Blasco, C.3    Sancho, J.V.4    Pico, Y.5    Hernandez, F.6
  • 48
    • 43849083096 scopus 로고    scopus 로고
    • Calculating human exposure to endocrine disrupting pesticides via agricultural and non-agricultural exposure routes
    • McKinlay R., Plant J.A., Bell J.N.B., Voulvoulis N. Calculating human exposure to endocrine disrupting pesticides via agricultural and non-agricultural exposure routes. Sci. Total Environ. 2008, 398:1-12.
    • (2008) Sci. Total Environ. , vol.398 , pp. 1-12
    • McKinlay, R.1    Plant, J.A.2    Bell, J.N.B.3    Voulvoulis, N.4
  • 49
    • 80051766939 scopus 로고    scopus 로고
    • Organic contamination of settled house dust, a review for exposure assessment purposes
    • Mercier F., Glorennec P., Thomas O., Le Bot B. Organic contamination of settled house dust, a review for exposure assessment purposes. Environ. Sci. Technol. 2011, 45:6716-6727.
    • (2011) Environ. Sci. Technol. , vol.45 , pp. 6716-6727
    • Mercier, F.1    Glorennec, P.2    Thomas, O.3    Le Bot, B.4
  • 52
    • 85011385846 scopus 로고    scopus 로고
    • National Research Council, The National Academic Press, Washington, DC, USA.
    • Human Biomonitoring for Environmental Chemicals 2006, National Research Council, The National Academic Press, Washington, DC, USA.
    • (2006) Human Biomonitoring for Environmental Chemicals
  • 53
    • 29844440960 scopus 로고    scopus 로고
    • Children[U+05F3]s exposure to environmental pollutants and biomarkers of genetic damage I. Overview and critical issues
    • Neri M., Bonassi S., Knudsen L., Sram R., Holland N., Ugolini D., Merlo D. Children[U+05F3]s exposure to environmental pollutants and biomarkers of genetic damage I. Overview and critical issues. Mutat. Res. - Rev. Mutat. Res. 2006, 612:1-13.
    • (2006) Mutat. Res. - Rev. Mutat. Res. , vol.612 , pp. 1-13
    • Neri, M.1    Bonassi, S.2    Knudsen, L.3    Sram, R.4    Holland, N.5    Ugolini, D.6    Merlo, D.7
  • 54
    • 77956876371 scopus 로고    scopus 로고
    • Quantification of dialkylphosphate metabolites of organophosphorus insecticides in human urine using 96-well plate sample preparation and high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry
    • Odetokun M.S., Montesano M.A., Weerasekera G., Whitehead R.D., Needham L.L., Barr D.B. Quantification of dialkylphosphate metabolites of organophosphorus insecticides in human urine using 96-well plate sample preparation and high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry. J. Chromatogr. B. Anal. Technol. Biomed. Life Sci. 2010.
    • (2010) J. Chromatogr. B. Anal. Technol. Biomed. Life Sci.
    • Odetokun, M.S.1    Montesano, M.A.2    Weerasekera, G.3    Whitehead, R.D.4    Needham, L.L.5    Barr, D.B.6
  • 55
    • 2342580801 scopus 로고    scopus 로고
    • A liquid chromatography-tandem mass spectrometry multiresidue method for quantification of specific metabolites of organophosphorus pesticides, synthetic pyrethroids, selected herbicides, and DEET in human urine
    • Olsson A.O., Baker S.E., Nguyen J.V., Romanoff L.C., Udunka S.O., Walker R.D., Flemmen K.L., Barr D.B. A liquid chromatography-tandem mass spectrometry multiresidue method for quantification of specific metabolites of organophosphorus pesticides, synthetic pyrethroids, selected herbicides, and DEET in human urine. Anal. Chem. 2004, 76:2453-2461.
    • (2004) Anal. Chem. , vol.76 , pp. 2453-2461
    • Olsson, A.O.1    Baker, S.E.2    Nguyen, J.V.3    Romanoff, L.C.4    Udunka, S.O.5    Walker, R.D.6    Flemmen, K.L.7    Barr, D.B.8
  • 57
    • 0642334467 scopus 로고    scopus 로고
    • Calculation and application of coverage intervals for biological reference values
    • Poulsen O.M., Holst E., Christensen J.M. Calculation and application of coverage intervals for biological reference values. Pure Appl. Chem. 1997, 68:1601-1611.
    • (1997) Pure Appl. Chem. , vol.68 , pp. 1601-1611
    • Poulsen, O.M.1    Holst, E.2    Christensen, J.M.3
  • 59
    • 79952102339 scopus 로고    scopus 로고
    • Correlating neurobehavioral performance with biomarkers of organophosphorous pesticide exposure
    • Rohlman D.S., Anger W.K., Lein P.J. Correlating neurobehavioral performance with biomarkers of organophosphorous pesticide exposure. Neurotoxicology 2011, 32:268-276.
    • (2011) Neurotoxicology , vol.32 , pp. 268-276
    • Rohlman, D.S.1    Anger, W.K.2    Lein, P.J.3
  • 60
    • 84872553417 scopus 로고    scopus 로고
    • Multi-residue analysis of pesticides in agricultural products by liquid chromatography time-of-flight mass spectrometry
    • Saito S., Nemoto S., Matsuda R. Multi-residue analysis of pesticides in agricultural products by liquid chromatography time-of-flight mass spectrometry. Food Hyg. Saf. Sci. 2012, 53:255-263.
    • (2012) Food Hyg. Saf. Sci. , vol.53 , pp. 255-263
    • Saito, S.1    Nemoto, S.2    Matsuda, R.3
  • 61
    • 80051795485 scopus 로고    scopus 로고
    • Update of the reference and HBM values derived by the German Human Biomonitoring Commission
    • Human Biomonitoring Commission of the German Federal Environment Agency
    • Schulz C., Wilhelm M., Heudorf U., Kolossa-Gehring M. Update of the reference and HBM values derived by the German Human Biomonitoring Commission. Int. J. Hyg. Environ. Health 2011, 215:26-35. Human Biomonitoring Commission of the German Federal Environment Agency.
    • (2011) Int. J. Hyg. Environ. Health , vol.215 , pp. 26-35
    • Schulz, C.1    Wilhelm, M.2    Heudorf, U.3    Kolossa-Gehring, M.4
  • 62
    • 61649117585 scopus 로고    scopus 로고
    • Determination of no-observed effect level (NOEL)-biomarker equivalents to interpret biomonitoring data for organophosphorus pesticides in children
    • Valcke M., Bouchard M. Determination of no-observed effect level (NOEL)-biomarker equivalents to interpret biomonitoring data for organophosphorus pesticides in children. Environ. Health 2009, 8:5.
    • (2009) Environ. Health , vol.8 , pp. 5
    • Valcke, M.1    Bouchard, M.2
  • 64
    • 84875520503 scopus 로고    scopus 로고
    • A systematic review of carcinogenic outcomes and potential mechanisms from exposure to 2,4-D and MCPA in the environment
    • von Stackelberg K. A systematic review of carcinogenic outcomes and potential mechanisms from exposure to 2,4-D and MCPA in the environment. J. Toxicol. 2013, 2013:1-53.
    • (2013) J. Toxicol. , vol.2013 , pp. 1-53
    • von Stackelberg, K.1


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