A novel insulin receptor-signaling platform and its link to insulin resistance and type 2 diabetes

Cellular Signalling

Volumn 26, Issue 6, 2014, Pages 1355-1368

  Alghamdi, Farah ^a,b   Guo, Merry ^a,c   Abdulkhalek, Samar ^a,d   Crawford, Nicola ^a,e   Amith, Schammim Ray ^a,f   Szewczuk, Myron R ^a  

^a QUEEN S UNIVERSITY   (Canada)

^b KING FAHD ARMED FORCES HOSPITAL   (Saudi Arabia)

^c UNIVERSITY OF OTTAWA   (Canada)

^d LERNER RESEARCH INSTITUTE   (United States)

^e MCMASTER UNIVERSITY   (Canada)

^f UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Insulin receptor; Matrix metalloproteinase 9; Neuraminidase 1

Indexed keywords

BIM 23127; G PROTEIN COUPLED RECEPTOR; GELATINASE B; GELATINASE INHIBITOR; ILOMASTAT; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR BETA; INSULIN RECEPTOR SUBSTRATE 1; N ACETYL 2,3 DIDEHYDRO 2 DEOXYNEURAMINIC ACID; NEURAMINIDASE 1; NEURAMINIDASE 3; NEURAMINIDASE 4; NEUROMEDIN B; OLANZAPINE; OSELTAMIVIR; PIPERAZINE; PROTEIN TYROSINE KINASE; SIALIDASE; SIALIDASE INHIBITOR; UNCLASSIFIED DRUG; BENZODIAZEPINE DERIVATIVE; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, HUMAN; MMP9 PROTEIN, HUMAN; NEU1 PROTEIN, HUMAN; NEU3 PROTEIN, HUMAN; NEUROLEPTIC AGENT; SOMATOMEDIN C RECEPTOR;

ANIMAL CELL; ARTICLE; CELL STIMULATION; CELL SURFACE; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; FIBROBLAST; HEPATOMA CELL; HUMAN; HUMAN CELL; INSULIN RESISTANCE; INTRACELLULAR SIGNALING; MACROPHAGE; MOLECULAR INTERACTION; MOUSE; MUCOLIPIDOSIS TYPE 1; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR BINDING; ANIMAL; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANIMALS; ANTIPSYCHOTIC AGENTS; BENZODIAZEPINES; CELL LINE, TUMOR; DIABETES MELLITUS, TYPE 2; HUMANS; INSULIN; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; MATRIX METALLOPROTEINASE 9; MICE; NEURAMINIDASE; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; RATS; RECEPTOR, IGF TYPE 1; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION;

EID: 84896479142     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2014.02.015     Document Type: Article

References (97)

1. Hirabara S.M., Gorjao R., Vinolo M.A., Rodrigues A.C., Nachbar R.T., Curi R. J. Biomed. Biotechnol. 2012, 2012:379024.
2. DeFronzo R.A., Ferrannini E. Diabetes Care 1991, 14(3):173-194.
3. Kahn S.E. Am. J. Med. 2000, 108(Suppl. 6a):2S-8S.
4. Mauvais-Jarvis F., Kahn C.R. Diabetes Metab. 2000, 26(6):433-448.
5. Martin B.C., Warram J.H., Krolewski A.S., Bergman R.N., Soeldner J.S., Kahn C.R. Lancet 1992, 340(8825):925-929.
6. Abdul-Ghani M.A., DeFronzo R.A. J. Biomed. Biotechnol. 2010, 2010:476279.
7. Kontrogianni-Konstantopoulos A., Benian G., Granzier H. J. Biomed. Biotechnol. 2010, 2010.
8. Maratou E., Hadjidakis D.J., Peppa M., Alevizaki M., Tsegka K., Lambadiari V., Mitrou P., Boutati E., Kollias A., Economopoulos T., Raptis S.A., Dimitriadis G. Eur. J. Endocrinol. 2010, 163(4):625-630.
9. Peppa M., Boutati E., Koliaki C., Papaefstathiou N., Garoflos E., Economopoulos T., Hadjidakis D., Raptis S.A. Metabolism 2010, 59(10):1435-1441.
10. Peppa M., Koliaki C., Nikolopoulos P., Raptis S.A. J. Biomed. Biotechnol. 2010, 2010:527850.
11. Martins A.R., Nachbar R.T., Gorjao R., Vinolo M.A., Festuccia W.T., Lambertucci R.H., Cury-Boaventura M.F., Silveira L.R., Curi R., Hirabara S.M. Lipids Health Dis. 2012, 11:30.
12. Blaise S., Romier B., Kawecki C., Ghirardi M., Rabenoelina F., Baud S., Duca L., Maurice P., Heinz A., Schmelzer C.E., Tarpin M., Martiny L., Garbar C., Dauchez M., Debelle L., Durlach V. Diabetes 2013, 62(11):3807-3816.
13. Salhanick A.I., Amatruda J.M. Am. J. Physiol. 1988, 255(2 Pt 1):E173-E179.
14. Ward C., Lawrence M., Streltsov V., Garrett T., McKern N., Lou M.Z., Lovrecz G., Adams T. Acta Physiol (Oxf) 2008, 192(1):3-9.
15. Sparrow L.G., Lawrence M.C., Gorman J.J., Strike P.M., Robinson C.P., McKern N.M., Ward C.W. Proteins 2008, 71(1):426-439.
16. Elleman T.C., Frenkel M.J., Hoyne P.A., McKern N.M., Cosgrove L., Hewish D.R., Jachno K.M., Bentley J.D., Sankovich S.E., Ward C.W. Biochem. J. 2000, 347(Pt 3):771-779.
17. Mayer J.P., Zhang F., DiMarchi R.D. Biopolymers 2007, 88(5):687-713.
18. Leconte I., Auzan C., Debant A., Rossi B., Clauser E. J. Biol. Chem. 1992, 267(24):17415-17423.
19. Ciaraldi T.P. Diabetes 1989, 38(8):951-958.
20. Arabkhari M., Bunda S., Wang Y., Wang A., Pshezhetsky A.V., Hinek A. Glycobiology 2010, 20(5):603-616.
21. Fanzani A., Giuliani R., Colombo F., Zizioli D., Presta M., Preti A., Marchesini S. FEBS Lett. 2003, 547(1-3):183-188.
22. Anastasia L., Papini N., Colazzo F., Palazzolo G., Tringali C., Dileo L., Piccoli M., Conforti E., Sitzia C., Monti E., Sampaolesi M., Tettamanti G., Venerando B. J. Biol. Chem. 2008, 283(52):36265-36271.
23. Sato K., Miyagi T. Biochem. Biophys. Res. Commun. 1996, 221(3):826-830.
24. Sasaki A., Hata K., Suzuki S., Sawada M., Wada T., Yamaguchi K., Obinata M., Tateno H., Suzuki H., Miyagi T. J. Biol. Chem. 2003, 278(30):27896-27902.
25. Alderton F., Rakhit S., Kong K.C., Palmer T., Sambi B., Pyne S., Pyne N.J. J. Biol. Chem. 2001, 276(30):28578-28585.
26. Rothenberg P.L., Kahn C.R. J. Biol. Chem. 1988, 263(30):15546-15552.
27. Luttrell L., Kilgour E., Larner J., Romero G. J. Biol. Chem. 1990, 265(28):16873-16879.
28. O'Brien R.M., Houslay M.D., Milligan G., Siddle K. FEBS Lett. 1987, 212(2):281-288.
29. Pyne N.J., Pyne S. Biochim. Biophys. Acta 2008, 1781(9):467-476.
30. Pyne N.J., Pyne S. Trends Pharmacol. Sci. 2011, 32(8):443-450.
31. Pyne N.J., Waters C., Moughal N.A., Sambi B.S., Pyne S. Biochem. Soc. Trans. 2003, 31(Pt 6):1220-1225.
32. Pyne N.J., Waters C.M., Long J.S., Moughal N.A., Tigyi G., Pyne S. Adv. Enzyme Regul. 2007, 47:271-280.
33. Abdulkhalek S., Hrynyk M., Szewczuk M.R. Research and Reports in Biochemistry 2013, 3:17-30.
34. Dridi L., Seyrantepe V., Fougerat A., Pan X., Bonneil E., Thibault P., Moreau A., Mitchell G.A., Heveker N., Cairo C.W., Issad T., Hinek A., Pshezhetsky A.V. Diabetes 2013, 62(7):2338-2346.
35. Slieker L.J., Lane M.D. J. Biol. Chem. 1985, 260(2):687-690.
36. Soderquist A.M., Carpenter G. J. Biol. Chem. 1984, 259(20):12586-12594.
37. Takahashi M., Tsuda T., Ikeda Y., Honke K., Taniguchi N. Glycoconj. J. 2004, 20(3):207-212.
38. Fernandes H., Cohen S., Bishayee S. J. Biol. Chem. 2001, 276(7):5375-5383.
39. Gilmour A.M., Abdulkhalek S., Cheng T.S., Alghamdi F., Jayanth P., O'Shea L.K., Geen O., Arvizu L.A., Szewczuk M.R. Cell. Signal. 2013, 25(12):2587-2603.
40. Ebenbichler C.F., Laimer M., Eder U., Mangweth B., Weiss E., Hofer A., Hummer M., Kemmler G., Lechleitner M., Patsch J.R., Fleischhacker W.W. J. Clin. Psychiatry 2003, 64(12):1436-1439.
41. Richards A.A., Hickman I.J., Wang A.Y., Jones A.L., Newell F., Mowry B.J., Whitehead J.P., Prins J.B., Macdonald G.A. J. Clin. Psychopharmacol. 2006, 26(3):232-237.
42. Engl J., Laimer M., Niederwanger A., Kranebitter M., Starzinger M., Pedrini M.T., Fleischhacker W.W., Patsch J.R., Ebenbichler C.F. Mol. Psychiatry 2005, 10(12):1089-1096.
43. Li M., Youngren J.F., Manchem V.P., Kozlowski M., Zhang B.B., Maddux B.A., Goldfine I.D. Diabetes 2001, 50(10):2323-2328.
44. Bifsha P., Landry K., Ashmarina L., Durand S., Seyrantepe V., Trudel S., Quiniou C., Chemtob S., Xu Y., Gravel R.A., Sladek R., Pshezhetsky A.V. Cell Death Differ. 2007, 14(3):511-523.
45. Seyrantepe V., Canuel M., Carpentier S., Landry K., Durand S., Liang F., Zeng J., Caqueret A., Gravel R.A., Marchesini S., Zwingmann C., Michaud J., Morales C.R., Levade T., Pshezhetsky A.V. Hum. Mol. Genet. 2008, 17(11):1556-1568.
46. Alatery A., Basta S. J. Immunol. Methods 2008, 338(1-2):47-57.
47. Woronowicz A., De Vusser K., Laroy W., Contreras R., Meakin S.O., Ross G.M., Szewczuk M.R. Glycobiology 2004, 14(11):987-998.
48. Amith S.R., Jayanth P., Finlay T., Franchuk S., Gilmour A., Abdulkhalek S., Szewczuk M.R. J. Vis. Exp. 2010, (43).
49. Jayanth P., Amith S.R., Gee K., Szewczuk M.R. Cell. Signal. 2010, 22(8):1193-1205.
50. Amith S.R., Jayanth P., Franchuk S., Finlay T., Seyrantepe V., Beyaert R., Pshezhetsky A.V., Szewczuk M.R. Cell. Signal. 2010, 22(2):314-324.
51. Abdulkhalek S., Amith S.R., Franchuk S.L., Jayanth P., Guo M., Finlay T., Gilmour A., Guzzo C., Gee K., Beyaert R., Szewczuk M.R. J. Biol. Chem. 2011, 286(42):36532-36549.
52. Abdulkhalek S., Szewczuk M.R. Cell. Signal. 2013, 25(11):2093-2105.
53. Woronowicz A., Amith S.R., De Vusser K., Laroy W., Contreras R., Basta S., Szewczuk M.R. Glycobiology 2007, 17(1):10-24.
54. Amith S.R., Jayanth P., Franchuk S., Siddiqui S., Seyrantepe V., Gee K., Basta S., Beyaert R., Pshezhetsky A.V., Szewczuk M.R. Glycoconj. J. 2009, 26(9):1197-1212.
55. Miyagi T., Sagawa J., Konno K., Tsuiki S. J. Biochem. (Tokyo) 1990, 107(5):794-798.
56. Lukong K.E., Elsliger M.A., Chang Y., Richard C., Thomas G., Carey W., Tylki-Szymanska A., Czartoryska B., Buchholz T., Criado G.R., Palmeri S., Pshezhetsky A.V. Hum. Mol. Genet. 2000, 9(7):1075-1085.
57. Liang F., Seyrantepe V., Landry K., Ahmad R., Ahmad A., Stamatos N.M., Pshezhetsky A.V. J. Biol. Chem. 2006, 281(37):27526-27538.
58. Nan X., Carubelli I., Stamatos N.M. J. Leukoc. Biol. 2007, 81(1):284-296.
59. Yogalingam G., Bonten E.J., van de Vlekkert D., Hu H., Moshiach S., Connell S.A., D'Azzo A. Dev. Cell 2008, 15(1):74-86.
60. Hinek A., Pshezhetsky A.V., Von I.M., Starcher B. J. Biol. Chem. 2006, 281(6):3698-3710.
61. Duca L., Blanchevoye C., Cantarelli B., Ghoneim C., Dedieu S., Delacoux F., Hornebeck W., Hinek A., Martiny L., Debelle L. J. Biol. Chem. 2007, 282(17):12484-12491.
62. Starcher B., D'Azzo A., Keller P.W., Rao G.K., Nadarajah D., Hinek A. Am. J. Physiol. Lung Cell. Mol. Physiol. 2008, 295(4):L637-L647.
63. Rodriguez J.A., Piddini E., Hasegawa T., Miyagi T., Dotti C.G. J. Neurosci. 2001, 21(21):8387-8395.
64. Papini N., Anastasia L., Tringali C., Croci G., Bresciani R., Yamaguchi K., Miyagi T., Preti A., Prinetti A., Prioni S., Sonnino S., Tettamanti G., Venerando B., Monti E. J. Biol. Chem. 2004, 279(17):16989-16995.
65. Yamaguchi K., Hata K., Koseki K., Shiozaki K., Akita H., Wada T., Moriya S., Miyagi T. Biochem. J. 2005, 390(Pt 1):85-93.
66. Seyrantepe V., Poupetova H., Froissart R., Zabot M.T., Maire I., Pshezhetsky A.V. Hum. Mutat. 2003, 22(5):343-352.
67. Hata K., Koseki K., Yamaguchi K., Moriya S., Suzuki Y., Yingsakmongkon S., Hirai G., Sodeoka M., von Itzstein M., Miyagi T. Antimicrob. Agents Chemother. 2008, 52(10):3484-3491.
68. Abdulkhalek S., Guo M., Amith S.R., Jayanth P., Szewczuk M.R. Cell. Signal. 2012, 24(11):2035-2042.
69. Fischoeder A., Meyborg H., Stibenz D., Fleck E., Graf K., Stawowy P. Cardiovasc. Res. 2007, 73(4):841-848.
70. DeLano F.A., Schmid-Schonbein G.W. Hypertension 2008, 52(2):415-423.
71. Shen K., Sung K.L., Whittemore D.E., DeLano F.A., Zweifach B.W., Schmid-Schonbein G.W. Biochem. Cell Biol. 1995, 73(7-8):491-500.
72. Camp T.M., Tyagi S.C., Senior R.M., Hayden M.R., Tyagi S.C. Diabetologia 2003, 46(10):1438-1445.
73. Camp T.M., Smiley L.M., Hayden M.R., Tyagi S.C. J. Hypertens. 2003, 21(9):1719-1727.
74. Zou Y., Albohy A., Sandbhor M., Cairo C.W. Bioorg. Med. Chem. Lett. 2010, 20(24):7529-7533.
75. Baron V., Gautier N., Komoriya A., Hainaut P., Scimeca J.C., Mervic M., Lavielle S., Dolais-Kitabgi J., Van Obberghen E. Biochemistry 1990, 29(19):4634-4641.
76. Lee J., Pilch P.F., Shoelson S.E., Scarlata S.F. Biochemistry 1997, 36(9):2701-2708.
77. Schlein M., Havelund S., Kristensen C., Dunn M.F., Kaarsholm N.C. J. Mol. Biol. 2000, 303(2):161-169.
78. Frankel M., Bishop S.M., Ablooglu A.J., Han Y.-P., Kohanski R.A. Protein Sci. 1999, 8(10):2158-2165.
79. Ullrich A., Bell J.R., Chen E.Y., Herrera R., Petruzzelli L.M., Dull T.J., Gray A., Coussens L., Liao Y.C., Tsubokawa M., et al. Nature 1985, 313(6005):756-761.
80. Sparrow L.G., McKern N.M., Gorman J.J., Strike P.M., Robinson C.P., Bentley J.D., Ward C.W. J. Biol. Chem. 1997, 272(47):29460-29467.
81. Hubbard S.R., Wei L., Ellis L., Hendrickson W.A. Nature 1994, 372(6508):746-754.
82. McDonald N.Q., Murray-Rust J., Blundell T.L. Structure 1995, 3(1):1-6.
83. Paula G.S., Souza L.L., Cabanelas A., Bloise F.F., Mello-Coelho V., Wada E., Ortiga-Carvalho T.M., Oliveira K.J., Pazos-Moura C.C. J. Physiol. 2010, 588(Pt 9):1635-1645.
84. Patel T.B. Pharmacol. Rev. 2004, 56(3):371-385.
85. Moody T.W., Berna M.J., Mantey S., Sancho V., Ridnour L., Wink D.A., Chan D., Giaccone G., Jensen R.T. Eur. J. Pharmacol. 2010, 637(1-3):38-45.
86. Fischer O.M., Hart S., Ullrich A. Methods Mol. Biol. 2006, 327:85-97.
87. Lee M.-H., Murphy G. J. Cell Sci. 2004, 117(18):4015-4016.
88. Le Gall S.M., Auger R., Dreux C., Mauduit P. J. Biol. Chem. 2003, 278(46):45255-45268.
89. Murasawa S., Mori Y., Nozawa Y., Gotoh N., Shibuya M., Masaki H., Maruyama K., Tsutsumi Y., Moriguchi Y., Shibazaki Y., Tanaka Y., Iwasaka T., Inada M., Matsubara H. Circ. Res. 1998, 82(12):1338-1348.
90. Gooz M., Gooz P., Luttrell L.M., Raymond J.R. J. Biol. Chem. 2006, 281(30):21004-21012.
91. Prenzel N., Zwick E., Daub H., Leserer M., Abraham R., Wallasch C., Ullrich A. Nature 1999, 402(6764):884-888.
92. Karoor V., Wang L., Wang H.Y., Malbon C.C. J. Biol. Chem. 1998, 273(49):33035-33041.
93. Karoor V., Malbon C.C. J. Biol. Chem. 1996, 271(46):29347-29352.
94. Baltensperger K., Karoor V., Paul H., Ruoho A., Czech M.P., Malbon C.C. J. Biol. Chem. 1996, 271(2):1061-1064.
95. Karoor V., Baltensperger K., Paul H., Czech M.P., Malbon C.C. J. Biol. Chem. 1995, 270(43):25305-25308.
96. Moon S.K., Cho S.H., Kim K.W., Jeon J.H., Ko J.H., Kim B.Y., Kim C.H. Biochem. Biophys. Res. Commun. 2007, 356(3):542-547.
97. Rusciani A., Duca L., Sartelet H., Chatron-Colliet A., Bobichon H., Ploton D., Le Naour R., Blaise S., Martiny L., Debelle L. PLoS One 2010, 5(11):e14010.