메뉴 건너뛰기




Volumn 637, Issue 1-3, 2010, Pages 38-45

Neuromedin B receptors regulate EGF receptor tyrosine phosphorylation in lung cancer cells

Author keywords

Epidermal growth factor receptor; Lung cancer; Neuromedin B; Reactive oxygen species; Transactivation

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; GASTRIN RELEASING PEPTIDE RECEPTOR; GEFITINIB; NEUROMEDIN B; NEUROPEPTIDE RECEPTOR; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 77953288763     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2010.03.057     Document Type: Article
Times cited : (51)

References (40)
  • 2
    • 15144343374 scopus 로고    scopus 로고
    • Epidermal growth factor (EGF)-induced generation of hydrogen peroxide. Role in EGF receptor-mediated tyrosine phosphorylation
    • Bae Y.S., Kang S.W., Seo M.S., Baines I.C., Tekle E., Chock P.B., Rhee S.G. Epidermal growth factor (EGF)-induced generation of hydrogen peroxide. Role in EGF receptor-mediated tyrosine phosphorylation. J. Biol. Chem. 1997, 272:217-221.
    • (1997) J. Biol. Chem. , vol.272 , pp. 217-221
    • Bae, Y.S.1    Kang, S.W.2    Seo, M.S.3    Baines, I.C.4    Tekle, E.5    Chock, P.B.6    Rhee, S.G.7
  • 3
    • 0027082327 scopus 로고
    • Neuromedin B receptors retain functional expression when transfected into BALB 3T3 fibroblasts: analysis of binding, kinetics, stoichiometry, modulation by guanine nucleotide-binding proteins, and signal transduction and comparison with natively expressed receptors
    • Benya R.V., Wada E., Battey J.F., Fathi Z., Wang L.H., Mantey S.A., Coy D.H., Jensen R.T. Neuromedin B receptors retain functional expression when transfected into BALB 3T3 fibroblasts: analysis of binding, kinetics, stoichiometry, modulation by guanine nucleotide-binding proteins, and signal transduction and comparison with natively expressed receptors. Mol. Pharmacol. 1992, 42:1058-1068.
    • (1992) Mol. Pharmacol. , vol.42 , pp. 1058-1068
    • Benya, R.V.1    Wada, E.2    Battey, J.F.3    Fathi, Z.4    Wang, L.H.5    Mantey, S.A.6    Coy, D.H.7    Jensen, R.T.8
  • 4
    • 33645331570 scopus 로고    scopus 로고
    • Src homology 2-containing phosphotyrosine phosphatase regulates endothelin-1-induced epidermal growth factor receptor transactivation in rat renal tubular cell NRK-52E
    • Cheng-Hsien C., Yung-Ho H., Yuh-Mou S., Chun-Cheng H., Horng-Mo L., Huei-Mei H., Tso-Hsiao C. Src homology 2-containing phosphotyrosine phosphatase regulates endothelin-1-induced epidermal growth factor receptor transactivation in rat renal tubular cell NRK-52E. Pflugers Arch. 2006, 452:16-24.
    • (2006) Pflugers Arch. , vol.452 , pp. 16-24
    • Cheng-Hsien, C.1    Yung-Ho, H.2    Yuh-Mou, S.3    Chun-Cheng, H.4    Horng-Mo, L.5    Huei-Mei, H.6    Tso-Hsiao, C.7
  • 5
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors
    • Chou T.C., Talalay P. Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv. Enzyme Regul. 1984, 22:27-55.
    • (1984) Adv. Enzyme Regul. , vol.22 , pp. 27-55
    • Chou, T.C.1    Talalay, P.2
  • 7
    • 0021807624 scopus 로고
    • Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer cells
    • Cuttitta F., Carney D.N., Mulshine J., Moody T.W., Fedorko J., Fischler A., Minna J.D. Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer cells. Nature 1985, 316:823-826.
    • (1985) Nature , vol.316 , pp. 823-826
    • Cuttitta, F.1    Carney, D.N.2    Mulshine, J.3    Moody, T.W.4    Fedorko, J.5    Fischler, A.6    Minna, J.D.7
  • 11
    • 33845803204 scopus 로고    scopus 로고
    • Antitumor activity of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib (ZD1839, Iressa) in non-small cell lung cancer cell lines correlates with gene copy number and EGFR mutations but not EGFR protein levels
    • Helfrich B.A., Raben D., Varella-Garcia M., Gustafson D., Chan D.C., Bemis L., Coldren C., Baron A., Zeng C., Franklin W.A., Hirsch F.R., Gazdar A.F., Minna J., Bunn P.A. Antitumor activity of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib (ZD1839, Iressa) in non-small cell lung cancer cell lines correlates with gene copy number and EGFR mutations but not EGFR protein levels. Clin. Cancer Res. 2006, 12:7117-7125.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 7117-7125
    • Helfrich, B.A.1    Raben, D.2    Varella-Garcia, M.3    Gustafson, D.4    Chan, D.C.5    Bemis, L.6    Coldren, C.7    Baron, A.8    Zeng, C.9    Franklin, W.A.10    Hirsch, F.R.11    Gazdar, A.F.12    Minna, J.13    Bunn, P.A.14
  • 12
    • 0037499945 scopus 로고    scopus 로고
    • Response to epidermal growth factor receptor inhibitors in non-small cell lung cancer cells: limited antiproliferative effects and absence of apoptosis associated with persistent activity of extracellular signal-regulated kinase or Akt kinase pathways
    • Janmaat M.L., Kruyt F.A., Rodriguez J.A., Giaccone G. Response to epidermal growth factor receptor inhibitors in non-small cell lung cancer cells: limited antiproliferative effects and absence of apoptosis associated with persistent activity of extracellular signal-regulated kinase or Akt kinase pathways. Clin. Cancer Res. 2003, 9:2316-2326.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 2316-2326
    • Janmaat, M.L.1    Kruyt, F.A.2    Rodriguez, J.A.3    Giaccone, G.4
  • 13
    • 33751189441 scopus 로고    scopus 로고
    • Bombesin-related peptides and neurotensin: effects on cancer growth/proliferation and cellular signaling in cancer
    • Elsevier, Amsterdam, A. Kastin (Ed.)
    • Jensen R.T., Moody T.W. Bombesin-related peptides and neurotensin: effects on cancer growth/proliferation and cellular signaling in cancer. Handbook of Biologically Active Peptides 2006, 429-434. Elsevier, Amsterdam. A. Kastin (Ed.).
    • (2006) Handbook of Biologically Active Peptides , pp. 429-434
    • Jensen, R.T.1    Moody, T.W.2
  • 14
    • 0035051948 scopus 로고    scopus 로고
    • The case for gastrin-releasing peptide acting as a morphogen when it and its receptor are aberrantly expressed in cancer
    • Jensen J.A., Carroll R.E., Benya R.V. The case for gastrin-releasing peptide acting as a morphogen when it and its receptor are aberrantly expressed in cancer. Peptides 2001, 22:689-699.
    • (2001) Peptides , vol.22 , pp. 689-699
    • Jensen, J.A.1    Carroll, R.E.2    Benya, R.V.3
  • 15
    • 41149176081 scopus 로고    scopus 로고
    • International union of pharmacology. LVIII. Mammalian bombesin receptors: nomenclature, distribution, pharmacology, signaling and functions in normal and disease states
    • Jensen R.T., Battey J.F., Spindel E.R., Benya R.V. International union of pharmacology. LVIII. Mammalian bombesin receptors: nomenclature, distribution, pharmacology, signaling and functions in normal and disease states. Pharmacol. Rev. 2008, 60:1-42.
    • (2008) Pharmacol. Rev. , vol.60 , pp. 1-42
    • Jensen, R.T.1    Battey, J.F.2    Spindel, E.R.3    Benya, R.V.4
  • 16
    • 0028800366 scopus 로고
    • Mitogenic signaling by transfected neuromedin B receptors in Rat-1 cells
    • Lach E.B., Broad S., Rozengurt E. Mitogenic signaling by transfected neuromedin B receptors in Rat-1 cells. Cell Growth Differ 1995, 6:1427-1435.
    • (1995) Cell Growth Differ , vol.6 , pp. 1427-1435
    • Lach, E.B.1    Broad, S.2    Rozengurt, E.3
  • 18
    • 33947727520 scopus 로고    scopus 로고
    • Gastrin-releasing peptide activates Akt through the epidermal growth factor receptor pathway and abrogates the effect of gefitinib
    • Liu X., Carlisle D.L., Swick M.C., Gaither-Davis A., Grandis J.R., Siegfried J.M. Gastrin-releasing peptide activates Akt through the epidermal growth factor receptor pathway and abrogates the effect of gefitinib. Exp. Cell Res. 2007, 313:1361-1372.
    • (2007) Exp. Cell Res. , vol.313 , pp. 1361-1372
    • Liu, X.1    Carlisle, D.L.2    Swick, M.C.3    Gaither-Davis, A.4    Grandis, J.R.5    Siegfried, J.M.6
  • 19
    • 0142025133 scopus 로고    scopus 로고
    • Mitogenic effects of gastrin-releasing peptide in head and neck squamous cancer cells are mediated by activation of the epidermal growth factor receptor
    • Lui V.W., Thomas S.M., Zhang Q., Wentzel A.M., Siegfried J.M., Li J.Y., Grandis J.R. Mitogenic effects of gastrin-releasing peptide in head and neck squamous cancer cells are mediated by activation of the epidermal growth factor receptor. Oncogene 2003, 22:6183-6193.
    • (2003) Oncogene , vol.22 , pp. 6183-6193
    • Lui, V.W.1    Thomas, S.M.2    Zhang, Q.3    Wentzel, A.M.4    Siegfried, J.M.5    Li, J.Y.6    Grandis, J.R.7
  • 21
    • 0030867843 scopus 로고    scopus 로고
    • Discovery of a high affinity radioligand for the human orphan receptor, bombesin receptor subtype 3, which demonstrates it has a unique pharmacology compared to other mammalian bombesin receptors
    • Mantey S.A., Weber H.C., Sainz E., Akeson M., Ryan R.R., Pradhan T.K., Searles R.P., Spindel E.R., Battey J.F., Coy D.H., Jensen R.T. Discovery of a high affinity radioligand for the human orphan receptor, bombesin receptor subtype 3, which demonstrates it has a unique pharmacology compared to other mammalian bombesin receptors. J. Biol. Chem. 1997, 272:26062-26071.
    • (1997) J. Biol. Chem. , vol.272 , pp. 26062-26071
    • Mantey, S.A.1    Weber, H.C.2    Sainz, E.3    Akeson, M.4    Ryan, R.R.5    Pradhan, T.K.6    Searles, R.P.7    Spindel, E.R.8    Battey, J.F.9    Coy, D.H.10    Jensen, R.T.11
  • 22
    • 0026709439 scopus 로고
    • Neuromedin B binds with high affinity, elevates cytosolic calcium and stimulates the growth of small cell lung cancer cell lines
    • Moody T.W., Staley J., Zia F., Coy D.H., Jensen R.T. Neuromedin B binds with high affinity, elevates cytosolic calcium and stimulates the growth of small cell lung cancer cell lines. J. Pharmacol. Exp. Ther. 1992, 263:311-317.
    • (1992) J. Pharmacol. Exp. Ther. , vol.263 , pp. 311-317
    • Moody, T.W.1    Staley, J.2    Zia, F.3    Coy, D.H.4    Jensen, R.T.5
  • 23
    • 0030299972 scopus 로고    scopus 로고
    • BW 1023U90: a new GRP receptor antagonist for small-cell lung cancer cells
    • Moody T.W., Venugopal R., Hu V., Gozes Y., McDermed J., Leban J.J. BW 1023U90: a new GRP receptor antagonist for small-cell lung cancer cells. Peptides 1996, 17:1337-1343.
    • (1996) Peptides , vol.17 , pp. 1337-1343
    • Moody, T.W.1    Venugopal, R.2    Hu, V.3    Gozes, Y.4    McDermed, J.5    Leban, J.J.6
  • 24
    • 0034624267 scopus 로고    scopus 로고
    • Nonpeptide neuromedin B receptor antagonists inhibit the proliferation of C6 cells
    • Moody T.W., Jensen R.T., Garcia L., Leyton J. Nonpeptide neuromedin B receptor antagonists inhibit the proliferation of C6 cells. Eur. J. Pharmacol. 2000, 409:133-142.
    • (2000) Eur. J. Pharmacol. , vol.409 , pp. 133-142
    • Moody, T.W.1    Jensen, R.T.2    Garcia, L.3    Leyton, J.4
  • 25
    • 2542477191 scopus 로고    scopus 로고
    • Development of high affinity camptothecin-bombesin conjugates that have targeted cytotoxicity for bombesin receptor-containing tumor cells
    • Moody T.W., Mantey S.A., Pradhan T.K., Schumann M., Nakagawa T., Martinez A., Jensen R.T. Development of high affinity camptothecin-bombesin conjugates that have targeted cytotoxicity for bombesin receptor-containing tumor cells. J. Biol. Chem. 2004, 279:23580-23589.
    • (2004) J. Biol. Chem. , vol.279 , pp. 23580-23589
    • Moody, T.W.1    Mantey, S.A.2    Pradhan, T.K.3    Schumann, M.4    Nakagawa, T.5    Martinez, A.6    Jensen, R.T.7
  • 26
    • 2642570481 scopus 로고    scopus 로고
    • Sensitivity to gefitinib (Iressa, ZD1839) in non-small cell lung cancer cell lines correlates with dependence on the epidermal growth factor (EGF) receptor/extracellular signal-regulated kinase 1/2 and EGF receptor/Akt pathway for proliferation
    • Ono M., Hirata A., Kometani T., Miyagawa M., Ueda S., Kinoshita H., Fujii T., Kuwano M. Sensitivity to gefitinib (Iressa, ZD1839) in non-small cell lung cancer cell lines correlates with dependence on the epidermal growth factor (EGF) receptor/extracellular signal-regulated kinase 1/2 and EGF receptor/Akt pathway for proliferation. Mol. Cancer Ther. 2004, 3:465-472.
    • (2004) Mol. Cancer Ther. , vol.3 , pp. 465-472
    • Ono, M.1    Hirata, A.2    Kometani, T.3    Miyagawa, M.4    Ueda, S.5    Kinoshita, H.6    Fujii, T.7    Kuwano, M.8
  • 29
    • 0036554956 scopus 로고    scopus 로고
    • Bombesin receptor subtypes in human cancers: detection with the universal radioligand (125)I-[D-TYR(6), beta-ALA(11), PHE(13), NLE(14)] bombesin (6-14)
    • Reubi J.C., Wenger S., Schumuckli-Maurer J., Schaer J.C., Gugger M. Bombesin receptor subtypes in human cancers: detection with the universal radioligand (125)I-[D-TYR(6), beta-ALA(11), PHE(13), NLE(14)] bombesin (6-14). Clin. Cancer Res. 2002, 8:1139-1146.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 1139-1146
    • Reubi, J.C.1    Wenger, S.2    Schumuckli-Maurer, J.3    Schaer, J.C.4    Gugger, M.5
  • 31
    • 0142089835 scopus 로고    scopus 로고
    • Galardin (GM 6001), a broad-spectrum matrix metalloproteinase inhibitor, blocks bombesin- and LPA-induced EGF receptor transactivation and DNA synthesis in rat-1 cells
    • Santiskulvong C., Rozengurt E. Galardin (GM 6001), a broad-spectrum matrix metalloproteinase inhibitor, blocks bombesin- and LPA-induced EGF receptor transactivation and DNA synthesis in rat-1 cells. Exp. Cell Res. 2003, 290:437-446.
    • (2003) Exp. Cell Res. , vol.290 , pp. 437-446
    • Santiskulvong, C.1    Rozengurt, E.2
  • 32
    • 1342322686 scopus 로고    scopus 로고
    • Multiple G-protein-coupled receptor signals converge on the epidermal growth factor receptor to promote migration and invasion
    • Schafer B., Gschwind A., Ullrich A. Multiple G-protein-coupled receptor signals converge on the epidermal growth factor receptor to promote migration and invasion. Oncogene 2004, 23:991-999.
    • (2004) Oncogene , vol.23 , pp. 991-999
    • Schafer, B.1    Gschwind, A.2    Ullrich, A.3
  • 34
    • 18644367044 scopus 로고    scopus 로고
    • Gastrin-releasing peptide receptor mediates activation of the epidermal growth factor receptor in lung cancer cells
    • Thomas S.M., Grandis J.R., Wentzel A.L., Gooding W.E., Lui V.W., Siegfried J.M. Gastrin-releasing peptide receptor mediates activation of the epidermal growth factor receptor in lung cancer cells. Neoplasia 2005, 7:426-431.
    • (2005) Neoplasia , vol.7 , pp. 426-431
    • Thomas, S.M.1    Grandis, J.R.2    Wentzel, A.L.3    Gooding, W.E.4    Lui, V.W.5    Siegfried, J.M.6
  • 35
    • 0037306526 scopus 로고    scopus 로고
    • Redox-dependent MAP kinase signaling by Ang II in vascular smooth muscle cells: role of receptor tyrosine kinase transactivation
    • Touyz R.M., Cruzado M., Tabet F., Yao G., Salomon S., Schiffrin E.L. Redox-dependent MAP kinase signaling by Ang II in vascular smooth muscle cells: role of receptor tyrosine kinase transactivation. Can. J. Physiol. Pharmacol. 2003, 81:159-167.
    • (2003) Can. J. Physiol. Pharmacol. , vol.81 , pp. 159-167
    • Touyz, R.M.1    Cruzado, M.2    Tabet, F.3    Yao, G.4    Salomon, S.5    Schiffrin, E.L.6
  • 38
    • 0038107752 scopus 로고    scopus 로고
    • Activation of extracellular signal-regulated kinase mediates bombesin-induced mitogenic responses in prostate cancer cells
    • Xiao D., Qu X., Weber H.C. Activation of extracellular signal-regulated kinase mediates bombesin-induced mitogenic responses in prostate cancer cells. Cell Signal. 2003, 15:945-953.
    • (2003) Cell Signal. , vol.15 , pp. 945-953
    • Xiao, D.1    Qu, X.2    Weber, H.C.3
  • 39
    • 4344610825 scopus 로고    scopus 로고
    • SRC family kinases mediate epidermal growth factor receptor ligand cleavage, proliferation, and invasion of head and neck cancer cells
    • Zhang Q., Thomas S.M., Smithgall T.E., Siegfried J.M., Kamens J., Gooding W.E., Grandis J.R. SRC family kinases mediate epidermal growth factor receptor ligand cleavage, proliferation, and invasion of head and neck cancer cells. Cancer Res. 2004, 64:6166-6173.
    • (2004) Cancer Res. , vol.64 , pp. 6166-6173
    • Zhang, Q.1    Thomas, S.M.2    Smithgall, T.E.3    Siegfried, J.M.4    Kamens, J.5    Gooding, W.E.6    Grandis, J.R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.