Proteinase activity and receptor cleavage: Mechanism for insulin resistance in the spontaneously hypertensive rat

Hypertension

Volumn 52, Issue 2, 2008, Pages 415-423

  Delano, Frank A ^a   Schmid Schönbein, Geert W ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Insulin receptor; Integrin; Matrix metalloproteinases; Microcirculation; Oxygen free radical; Receptor cleavage

Indexed keywords

ANTIBODY; CD18 ANTIGEN; DOXYCYCLINE; GELATINASE B; GLYCOSYLATED HEMOGLOBIN; INSULIN RECEPTOR; INTERSTITIAL COLLAGENASE; PROTEINASE; MATRIX METALLOPROTEINASE; MYELOBLASTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; CHELATION; CONTROLLED STUDY; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; HYPERTENSION; IMMUNOHISTOCHEMISTRY; INSULIN RESISTANCE; LEUKOCYTE ADHERENCE; MALE; MICROVASCULATURE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; ANALYSIS OF VARIANCE; ANIMAL; BLOOD PRESSURE MEASUREMENT; COMPARATIVE STUDY; DISEASE MODEL; HEMODYNAMICS; LEUKOCYTE COUNT; METABOLISM; MICROCIRCULATION; PROBABILITY; RANDOMIZATION; REFERENCE VALUE; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION; WISTAR KYOTO RAT;

ANALYSIS OF VARIANCE; ANIMALS; BLOOD GLUCOSE; BLOOD PRESSURE DETERMINATION; DISEASE MODELS, ANIMAL; HEMODYNAMICS; HYPERTENSION; INSULIN RESISTANCE; LEUKOCYTE COUNT; MALE; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASES; MICROCIRCULATION; MYELOBLASTIN; PROBABILITY; RANDOM ALLOCATION; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RECEPTOR, INSULIN; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION;

EID: 49849083714     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.107.104356     Document Type: Article

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