Conformational changes in the activation loop of the insulin receptor's kinase domain

Protein Science

Volumn 8, Issue 10, 1999, Pages 2158-2165

  Frankel, Mark ^a   Bishop, Steven M ^a,b   Ablooglu, Ararat J ^a   Han, Yuan Ping ^a,c   Kohanski, Ronald A ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b GENENTECH INC   (United States)

^c CHILDREN S HOSPITAL LOS ANGELES   (United States)

Author keywords

Activation loop; Conformation; Limited proteolysis; Protein kinase

Indexed keywords

ADENINE NUCLEOTIDE; INSULIN RECEPTOR; PROTEIN KINASE; TRYPSIN;

ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DENATURATION; PROTEIN DOMAIN; PROTEIN STABILITY;

EID: 0032880050     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.8.10.2158     Document Type: Article

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