Glycosylation-induced conformational modification positively regulates receptor-receptor association: A study with an aberrant epidermal growth factor receptor (EGFRvIII/ΔEGFR) expressed in cancer cells

Journal of Biological Chemistry

Volumn 276, Issue 7, 2001, Pages 5375-5383

  Fernandes, Helen ^b   Cohen, Stanley ^b   Bishayee, Subal ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BRAIN; CONFORMATIONS; DIMERIZATION; ENZYMES; SIGNALING; SKIN; TUMORS;

GLYCOSYLATION; PHOSPHORYLATION;

CELLS;

AMINO ACID; ASPARAGINE; DIMER; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; MONOMER; MUTANT PROTEIN; PHOSPHOPEPTIDE; PROTEIN TYROSINE KINASE; STAT PROTEIN; TYROSINE; ANTIBODY; TUNICAMYCIN;

AMINO ACID SEQUENCE; ANTIBODY SPECIFICITY; ARTICLE; AUTOPHOSPHORYLATION; BINDING SITE; BRAIN TUMOR; BREAST TUMOR; CANCER CELL; CARCINOGENICITY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DIMERIZATION; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE DELETION; GENE MUTATION; GLIOBLASTOMA; HUMAN; HUMAN CELL; LIGAND BINDING; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SKIN TUMOR; STRUCTURE ANALYSIS; WILD TYPE; CELL CULTURE; CHEMISTRY; GENETICS; GLYCOSYLATION; IMMUNOLOGY; METABOLISM; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE;

ANTIBODIES; DIMERIZATION; ENZYME ACTIVATION; GLIOBLASTOMA; GLYCOSYLATION; HUMANS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, EPIDERMAL GROWTH FACTOR; SEQUENCE DELETION; TUMOR CELLS, CULTURED; TUNICAMYCIN;

EID: 0035895916     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M005599200     Document Type: Article

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