Premature CD4+ T cell aging and its contribution to lymphopenia-induced proliferation of memory cells in autoimmune-prone non-obese diabetic mice

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Sheu, Ting Ting ^a   Chiang, Bor Luen ^b,c   Yen, Jui Hung ^a   Lin, Wen Chi ^a  

^a TZU CHI UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CD4 ANTIGEN; FAS ANTIGEN; HERMES ANTIGEN; INTERLEUKIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNE DISEASE; CD4 LYMPHOCYTE COUNT; CD4+ T LYMPHOCYTE; CELL LOSS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIABETOGENESIS; DISEASE PREDISPOSITION; FEMALE; IMMUNOPATHOGENESIS; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTOPENIA; LYMPHOPENIA INDUCED PROLIFERATION; MEMORY CELL; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PREMATURE AGING; REGULATORY T LYMPHOCYTE; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CELL AGING; CELL PROLIFERATION; CYTOLOGY; EXPERIMENTAL DIABETES MELLITUS; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; OBESITY;

ANIMALS; ANTIGENS, CD28; CD4-POSITIVE T-LYMPHOCYTES; CELL AGING; CELL PROLIFERATION; DIABETES MELLITUS, EXPERIMENTAL; FEMALE; IMMUNOLOGIC MEMORY; INTERLEUKIN-2; LYMPHOPENIA; MICE; MICE, INBRED BALB C; MICE, INBRED NOD; OBESITY;

EID: 84896306996     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0089379     Document Type: Article

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