A role for mitogen kinase kinase 3 in pulmonary inflammation validated from a proteomic approach

Pulmonary Pharmacology and Therapeutics

Volumn 27, Issue 2, 2014, Pages 156-163

  Holand, T ^a   Riffo Vasquez, Y ^a   Spina, D ^a   O'Connor, B ^a   Woisin, F ^a   Sand, C ^a   Marber, M ^b   Bacon, K B ^c,e   Rohlff, C ^d,f   Page, C P ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b ST THOMAS HOSPITAL   (United Kingdom)

^c BAYER PHARMA AG   (Germany)

^d Formerly Oxford Glycosciences   (United Kingdom)

^e Axikin Pharmaceuticals Inc   (United States)

^f Oxford BioTherapeutics   (United Kingdom)

Author keywords

Asthma; Inflammation; MKK3; Neutrophils; Proteomics

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CD8 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 12; INTERLEUKIN 5; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE KINASE 3; OVALBUMIN; TUMOR NECROSIS FACTOR ALPHA; MAP2K3 PROTEIN, HUMAN; MAP2K3 PROTEIN, MOUSE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; EOSINOPHILIA; FEMALE; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IN VIVO STUDY; ISOELECTRIC FOCUSING; LEUKOCYTE ACTIVATION; LEUKOCYTE DIFFERENTIAL COUNT; LUNG LAVAGE; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOUSE; NEUTROPHILIA; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEOMICS; SCANNING ELECTRON MICROSCOPY; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY; YOUNG ADULT; ANIMAL; C57BL MOUSE; CASE CONTROL STUDY; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; MONONUCLEAR CELL; NEUTROPHIL; PATHOPHYSIOLOGY; PNEUMONIA; PROCEDURES; VALIDATION STUDY; WESTERN BLOTTING;

ADULT; ANIMALS; ASTHMA; BLOTTING, WESTERN; CASE-CONTROL STUDIES; CD8-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; MAP KINASE KINASE 3; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTROPHILS; PNEUMONIA; PROTEOMICS; YOUNG ADULT;

EID: 84895923848     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2014.01.006     Document Type: Article

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