Induction of beta defensin 2 by NTHi requires TLR2 mediated MyD88 and IRAK-TRAF6-p38MAPK signaling pathway in human middle ear epithelial cells

BMC Infectious Diseases

Volumn 8, Issue , 2008, Pages

  Lee, Haa Yung ^a   Takeshita, Tamotsu ^a,b   Shimada, Jun ^a,c   Akopyan, Arsen ^a   Woo, Jeong Im ^a   Pan, Huiqi ^a   Moon, Sung K ^a   Andalibi, Ali ^a   Park, Rae Kil ^a,d   Kang, Sung Ho ^e   Kang, Shin Seok ^a   Gellibolian, Robert ^a   Lim, David J ^a,f,g  

^a HOUSE EAR INSTITUTE   (United States)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^d Wonkwang University School of Medicine   (South Korea)

^e Konkuk University School of Medicine   (South Korea)

^f UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^g UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA DEFENSIN 2; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; INTERLEUKIN 1ALPHA; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCLONAL ANTIBODY; MYELOID DIFFERENTIATION FACTOR 88; SMALL INTERFERING RNA; TOLL LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; BETA DEFENSIN; DEFB4 PROTEIN, HUMAN; IRAK1 PROTEIN, HUMAN;

ARTICLE; BACTERIAL STRAIN; CELL LYSATE; CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; HUMAN CELL; INNATE IMMUNITY; MACROMOLECULE; MIDDLE EAR; MOLECULAR EVOLUTION; PARACRINE SIGNALING; PLASMID; PROTEIN EXPRESSION; PROTEIN INDUCTION; RESPIRATORY TRACT MUCOSA; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; STUDENT T TEST; UPREGULATION; ANIMAL; C57BL MOUSE; CELL LINE; CYTOLOGY; GENETICS; HAEMOPHILUS INFLUENZAE; IMMUNOLOGY; MALE; METABOLISM; MICROBIOLOGY; MOUSE; PATHOGENICITY;

ANIMALS; BETA-DEFENSINS; CELL LINE; EAR, MIDDLE; EPITHELIAL CELLS; HAEMOPHILUS INFLUENZAE; HUMANS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; MALE; MICE; MICE, INBRED C57BL; MYELOID DIFFERENTIATION FACTOR 88; P38 MITOGEN-ACTIVATED PROTEIN KINASES; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 6; TOLL-LIKE RECEPTOR 2; UP-REGULATION;

EID: 47749123025     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-8-87     Document Type: Article

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