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Volumn 15, Issue 16, 1996, Pages 4156-4164

Purification and cDNA cloning of SAPKK3, the major activator of RK/p38 in stress- and cytokine-stimulated monocytes and epithelial cells

Author keywords

Cytokine; IL 1; LPS; MAP kinase kinase; TNF

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; COMPLEMENTARY DNA; CYTOKINE; INTERLEUKIN 1; PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

EID: 0029782176     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00790.x     Document Type: Article
Times cited : (117)

References (35)
  • 1
    • 0025019946 scopus 로고
    • Subcellular fate of int-2 oncoprotein is determined by choice of initiation codon
    • Acland, P., Dixon, M., Peters, G. and Dickson, C. (1990) Subcellular fate of int-2 oncoprotein is determined by choice of initiation codon. Nature, 343, 662-665.
    • (1990) Nature , vol.343 , pp. 662-665
    • Acland, P.1    Dixon, M.2    Peters, G.3    Dickson, C.4
  • 3
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem., 72, 248-254.
    • (1976) Anal Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 4
    • 0028793798 scopus 로고
    • Induction of c-fos expression through JNK-mediated TCF/Elk1 phosphorylation
    • Cavigelli, M., Dolfi, F., Claret, F.-X. and Karin, M. (1995) Induction of c-fos expression through JNK-mediated TCF/Elk1 phosphorylation. EMBO J., 14, 5957-5964.
    • (1995) EMBO J. , vol.14 , pp. 5957-5964
    • Cavigelli, M.1    Dolfi, F.2    Claret, F.-X.3    Karin, M.4
  • 5
    • 0028988138 scopus 로고
    • SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
    • Cuenda, A., Rouse, J., Doza, Y.N., Meier, R., Cohen, P., Gallagher, T.F., Young, P.R. and Lee, J.C. (1995) SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett., 364, 229-233.
    • (1995) FEBS Lett. , vol.364 , pp. 229-233
    • Cuenda, A.1    Rouse, J.2    Doza, Y.N.3    Meier, R.4    Cohen, P.5    Gallagher, T.F.6    Young, P.R.7    Lee, J.C.8
  • 6
    • 0028329953 scopus 로고
    • JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
    • Derijard, B., Hibi, M., Wu, I.-H., Barrett, T., Su, B., Deng, T., Karin, M. and Davis, R.J. (1994) JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell, 76, 1025-1037.
    • (1994) Cell , vol.76 , pp. 1025-1037
    • Derijard, B.1    Hibi, M.2    Wu, I.-H.3    Barrett, T.4    Su, B.5    Deng, T.6    Karin, M.7    Davis, R.J.8
  • 7
    • 0028935974 scopus 로고
    • Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms
    • Derijard, B., Raingeaud, J., Barrett, T., Wu, I.-H., Han, J., Ulevitch, R.J. and Davis, R.J. (1995) Independent human MAP kinase signal transduction pathways defined by MEK and MKK isoforms. Science, 267, 682-684.
    • (1995) Science , vol.267 , pp. 682-684
    • Derijard, B.1    Raingeaud, J.2    Barrett, T.3    Wu, I.-H.4    Han, J.5    Ulevitch, R.J.6    Davis, R.J.7
  • 8
    • 0028969480 scopus 로고
    • Activation of the MAP kinase homologue RK requires the phosphorylation of Thr-180 and Tyr-182 and both residues are phosphorylated in chemically stressed KB cells
    • Doza, Y.N., Cuenda, A., Thomas, G.M., Cohen, P. and Nebreda, A.R. (1995) Activation of the MAP kinase homologue RK requires the phosphorylation of Thr-180 and Tyr-182 and both residues are phosphorylated in chemically stressed KB cells. FEBS Lett., 364, 223-228.
    • (1995) FEBS Lett. , vol.364 , pp. 223-228
    • Doza, Y.N.1    Cuenda, A.2    Thomas, G.M.3    Cohen, P.4    Nebreda, A.R.5
  • 9
    • 0028015872 scopus 로고
    • Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of hsp27
    • Freshney, N.W., Rawlinson, L., Guesdon, F., Jones, E., Cowley, S., Hsuan, J. and Saklatvala, J. (1994) Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of hsp27. Cell, 78, 1039-1049.
    • (1994) Cell , vol.78 , pp. 1039-1049
    • Freshney, N.W.1    Rawlinson, L.2    Guesdon, F.3    Jones, E.4    Cowley, S.5    Hsuan, J.6    Saklatvala, J.7
  • 10
    • 0025153488 scopus 로고
    • Evidence for communication between nerve growth factor and protein tyrosine phosphorylation
    • Gomez, N., Tonks, N.K., Morrison, C. Harmar, A.J. and Cohen, P. (1990) Evidence for communication between nerve growth factor and protein tyrosine phosphorylation. FEBS Lett., 271, 119-122.
    • (1990) FEBS Lett. , vol.271 , pp. 119-122
    • Gomez, N.1    Tonks, N.K.2    Morrison, C.3    Harmar, A.J.4    Cohen, P.5
  • 11
    • 0028905076 scopus 로고
    • Transcription factor ATF2 regulation by the JNK signal transduction pathway
    • Gupta, S., Campbell, D., Derijard, B. and Davis, R.J. (1995) Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science, 267, 389-393.
    • (1995) Science , vol.267 , pp. 389-393
    • Gupta, S.1    Campbell, D.2    Derijard, B.3    Davis, R.J.4
  • 12
    • 0027936755 scopus 로고
    • A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
    • Han, J., Lee, J.D., Bibbs, L. and Ulevitch, R.J. (1994) A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science, 265, 808-811.
    • (1994) Science , vol.265 , pp. 808-811
    • Han, J.1    Lee, J.D.2    Bibbs, L.3    Ulevitch, R.J.4
  • 13
    • 0030044182 scopus 로고    scopus 로고
    • Characterization of the structure and function of a novel MAP kinase kinase (MKK6)
    • Han, J., Lee, J.D., Jiang, Y., Li, Z., Feng, L. and Ulevitch, R.J. (1996) Characterization of the structure and function of a novel MAP kinase kinase (MKK6). J. Biol. Chem., 271, 2886-2891.
    • (1996) J. Biol. Chem. , vol.271 , pp. 2886-2891
    • Han, J.1    Lee, J.D.2    Jiang, Y.3    Li, Z.4    Feng, L.5    Ulevitch, R.J.6
  • 14
    • 0023885305 scopus 로고
    • The protein kinase family: Conserved features and deduced phylogeny of the catalytic domains
    • Hanks, S.K., Quinn, A.M. and Hunter, T. (1988) The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science, 241, 42-52.
    • (1988) Science , vol.241 , pp. 42-52
    • Hanks, S.K.1    Quinn, A.M.2    Hunter, T.3
  • 15
    • 0023872206 scopus 로고
    • A non-AUG translational intiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomas
    • Hann, S.R., King, M.W., Bentley, D.L., Anderson, C.W. and Eisenman, R.N. (1988) A non-AUG translational intiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomas. Cell, 52, 185-195.
    • (1988) Cell , vol.52 , pp. 185-195
    • Hann, S.R.1    King, M.W.2    Bentley, D.L.3    Anderson, C.W.4    Eisenman, R.N.5
  • 16
    • 0027423418 scopus 로고
    • Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain
    • Hibi, M., Lin, A., Smeal, T., Minden, A. and Karin, M. (1993) Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain. Genes Dev., 7, 2135-2148.
    • (1993) Genes Dev. , vol.7 , pp. 2135-2148
    • Hibi, M.1    Lin, A.2    Smeal, T.3    Minden, A.4    Karin, M.5
  • 17
    • 0028832107 scopus 로고
    • Characterization of 45-kDa/54-kDa HSP27 kinase, a stress-sensitive kinase which may activate the phosphorylation-dependent protective function of mammalian 27-kDa heat shock protein HSP27
    • Huot, J., Lambert, H., Lavoie, J.N., Guimond, A., Houle, F. and Landry, J. (1995) Characterization of 45-kDa/54-kDa HSP27 kinase, a stress-sensitive kinase which may activate the phosphorylation-dependent protective function of mammalian 27-kDa heat shock protein HSP27. Eur. J. Biochem., 227, 416-427.
    • (1995) Eur. J. Biochem. , vol.227 , pp. 416-427
    • Huot, J.1    Lambert, H.2    Lavoie, J.N.3    Guimond, A.4    Houle, F.5    Landry, J.6
  • 18
    • 0023665902 scopus 로고
    • An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs
    • Kozak, M. (1987) An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res., 15, 8125-8148.
    • (1987) Nucleic Acids Res. , vol.15 , pp. 8125-8148
    • Kozak, M.1
  • 20
    • 0027215820 scopus 로고
    • A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf
    • Lange-Carter, C.A., Pleiman, C.M., Gardner, A.M., Blumer, K.J. and Johnson, G.L. (1993) A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf. Science, 260, 315-319.
    • (1993) Science , vol.260 , pp. 315-319
    • Lange-Carter, C.A.1    Pleiman, C.M.2    Gardner, A.M.3    Blumer, K.J.4    Johnson, G.L.5
  • 21
    • 0028605318 scopus 로고
    • A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
    • Lee, J.C. et al. (1994) A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature, 372, 739-746.
    • (1994) Nature , vol.372 , pp. 739-746
    • Lee, J.C.1
  • 23
    • 0025820850 scopus 로고
    • Two isoforms of murine hck, generated by utilization of alternative translational intiation codons, exhibit different patterns of subcellular localization
    • Lock, P., Ralph, S., Stanley, E., Boulet, I., Ramsay, R. and Dunn, A.R. (1991) Two isoforms of murine hck, generated by utilization of alternative translational intiation codons, exhibit different patterns of subcellular localization. Mol. Cell. Biol., 11, 4363-4370.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 4363-4370
    • Lock, P.1    Ralph, S.2    Stanley, E.3    Boulet, I.4    Ramsay, R.5    Dunn, A.R.6
  • 25
    • 0029930461 scopus 로고    scopus 로고
    • Cellular stresses and cytokines activate multiple mitogen-activated-protein kinase kinase homologues in PC12 and KB cells
    • Meier, R., Rouse, J., Cuenda, A., Nebreda, A.R. and Cohen, P. (1996) Cellular stresses and cytokines activate multiple mitogen-activated-protein kinase kinase homologues in PC12 and KB cells. Eur. J. Biochem., 236, 796-805.
    • (1996) Eur. J. Biochem. , vol.236 , pp. 796-805
    • Meier, R.1    Rouse, J.2    Cuenda, A.3    Nebreda, A.R.4    Cohen, P.5
  • 27
    • 0030051528 scopus 로고    scopus 로고
    • MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway
    • Raingeaud, J., Whitmarsh, A.J., Barrett, T., Derijard, B. and Davis, R.J. (1996) MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol. Cell. Biol., 16, 1247-1255.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1247-1255
    • Raingeaud, J.1    Whitmarsh, A.J.2    Barrett, T.3    Derijard, B.4    Davis, R.J.5
  • 28
    • 0028022750 scopus 로고
    • A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
    • Rouse, J., Cohen, P., Trigon, S., Morange, M., Alonso-Llamazares, A., Zamanillo, D., Hunt, T. and Nebreda, A.R. (1994) A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell, 78, 1027-1037.
    • (1994) Cell , vol.78 , pp. 1027-1037
    • Rouse, J.1    Cohen, P.2    Trigon, S.3    Morange, M.4    Alonso-Llamazares, A.5    Zamanillo, D.6    Hunt, T.7    Nebreda, A.R.8
  • 29
    • 0028558986 scopus 로고
    • Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun
    • Sanchez, I., Hughes, R.T., Mayer, B.J., Yee, K., Woodgett, J.R., Avruch, J., Kyriakis, J.M. and Zon, L.I. (1994) Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature, 372, 794-798.
    • (1994) Nature , vol.372 , pp. 794-798
    • Sanchez, I.1    Hughes, R.T.2    Mayer, B.J.3    Yee, K.4    Woodgett, J.R.5    Avruch, J.6    Kyriakis, J.M.7    Zon, L.I.8
  • 30
    • 0026457201 scopus 로고
    • Identification of MAPKAP kinase-2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins
    • Stokoe, D., Engel, K., Campbell, D.G., Cohen, P. and Gaestel, M. (1992) Identification of MAPKAP kinase-2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins. FEBS Lett., 313, 307-313.
    • (1992) FEBS Lett. , vol.313 , pp. 307-313
    • Stokoe, D.1    Engel, K.2    Campbell, D.G.3    Cohen, P.4    Gaestel, M.5
  • 31
    • 0029125757 scopus 로고
    • Integration of MAP kinase signal transduction pathways at the serum response element
    • Whitmarsh, A.J., Shore, P., Sarrocks, A.D. and Davis, R.J. (1995) Integration of MAP kinase signal transduction pathways at the serum response element. Science, 269, 403-407.
    • (1995) Science , vol.269 , pp. 403-407
    • Whitmarsh, A.J.1    Shore, P.2    Sarrocks, A.D.3    Davis, R.J.4
  • 32
    • 0028670788 scopus 로고
    • Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1
    • Yan, M., Dai, T., Deak, J.C., Kyriakis, J.M., Zon, L.I., Woodgett, J.R. and Templeton, D.J. (1994) Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1. Nature, 372, 798-800.
    • (1994) Nature , vol.372 , pp. 798-800
    • Yan, M.1    Dai, T.2    Deak, J.C.3    Kyriakis, J.M.4    Zon, L.I.5    Woodgett, J.R.6    Templeton, D.J.7
  • 33
    • 0027184134 scopus 로고
    • Novel members of the mitogen-activated protein kinase activator family in Xenopus laevis
    • Yashar, B.M., Kelley, C., Yee, K., Errede, B. and Zon, L.I. (1993) Novel members of the mitogen-activated protein kinase activator family in Xenopus laevis. Mol. Cell. Biol., 13, 5738-5748.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 5738-5748
    • Yashar, B.M.1    Kelley, C.2    Yee, K.3    Errede, B.4    Zon, L.I.5
  • 34
    • 0028818395 scopus 로고
    • Mxi2, a mitogen-activated protein kinase that recognizes and phosphorylates Max protein
    • Zervos, A.S., Faccio, L., Gatto, J.P., Kyriakis, J.M. and Brent, R. (1995) Mxi2, a mitogen-activated protein kinase that recognizes and phosphorylates Max protein. Proc. Natl Acad. Sci. USA, 92, 10531-10534.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 10531-10534
    • Zervos, A.S.1    Faccio, L.2    Gatto, J.P.3    Kyriakis, J.M.4    Brent, R.5
  • 35
    • 0029147738 scopus 로고
    • Protein synthesis inhibitors reveal differential regulation of mitogen-activated protein kinase and stress-activated protein kinase pathways that converge on Elk-1
    • Zinck, R., Cahill, M.A., Kracht, M., Sachsenmaier, C., Hipskind, R.A. and Nordheim, A. (1995) Protein synthesis inhibitors reveal differential regulation of mitogen-activated protein kinase and stress-activated protein kinase pathways that converge on Elk-1. Mol. Cell. Biol., 15, 4930-4938.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4930-4938
    • Zinck, R.1    Cahill, M.A.2    Kracht, M.3    Sachsenmaier, C.4    Hipskind, R.A.5    Nordheim, A.6


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