-
1
-
-
33947458464
-
The chemistry of the benzimidazoles
-
J.B. Wright The chemistry of the benzimidazoles Chem. Rev. 48 3 1951 397 541
-
(1951)
Chem. Rev.
, vol.48
, Issue.3
, pp. 397-541
-
-
Wright, J.B.1
-
2
-
-
0001277441
-
Isolation and properties of crystalline cobamide coenzymes containing benzimidazole or 5,6 dimethylbenzimidazole
-
H.A. Barker, R.D. Smyth, H. Weissbach, J.I. Toohey, J.N. Ladd, and B.E. Volcani Isolation and properties of crystalline cobamide coenzymes containing benzimidazole or 5,6 dimethylbenzimidazole J. Biol. Chem. 235 2 1960 480 488
-
(1960)
J. Biol. Chem.
, vol.235
, Issue.2
, pp. 480-488
-
-
Barker, H.A.1
Smyth, R.D.2
Weissbach, H.3
Toohey, J.I.4
Ladd, J.N.5
Volcani, B.E.6
-
3
-
-
0001400315
-
Benzimidazole derivatives: Spectrum of pharmacological activity and toxicological properties
-
A.A. Spasov, I.N. Yozhitsa, L.I. Bugaeva, and V.A. Anisimova Benzimidazole derivatives: spectrum of pharmacological activity and toxicological properties Pharm. Chem. J. 33 5 1999 232 243
-
(1999)
Pharm. Chem. J.
, vol.33
, Issue.5
, pp. 232-243
-
-
Spasov, A.A.1
Yozhitsa, I.N.2
Bugaeva, L.I.3
Anisimova, V.A.4
-
4
-
-
84888829889
-
Benzimidazole an important scaffold in drug discovery
-
S.L. Khokra, and D. Choudhary Benzimidazole an important scaffold in drug discovery Asian J. Biochem. Pharm. Res. 3 1 2011 476 486
-
(2011)
Asian J. Biochem. Pharm. Res.
, vol.3
, Issue.1
, pp. 476-486
-
-
Khokra, S.L.1
Choudhary, D.2
-
5
-
-
78649879904
-
Substituted benzimidazole derivatives as angiotensin II-AT1 receptor antagonist: A review
-
V.K. Vyas, and M. Ghate Substituted benzimidazole derivatives as angiotensin II-AT1 receptor antagonist: a review Mini-Rev. Med. Chem. 10 14 2010 1366 1384
-
(2010)
Mini-Rev. Med. Chem.
, vol.10
, Issue.14
, pp. 1366-1384
-
-
Vyas, V.K.1
Ghate, M.2
-
6
-
-
33644816310
-
Inflammation, pain, and chronic disease: An integrative approach to treatment and prevention
-
T. Edwards Inflammation, pain, and chronic disease: an integrative approach to treatment and prevention Altern. Ther. Health Med. 11 6 2005 20 27 (Pubitemid 43885298)
-
(2005)
Alternative Therapies in Health and Medicine
, vol.11
, Issue.6
, pp. 20-27
-
-
Edwards, T.1
-
7
-
-
84864445461
-
The economic costs of pain in the United States
-
D.J. Gaskin, and P. Richard The economic costs of pain in the United States J. Pain 13 8 2012 715 724
-
(2012)
J. Pain
, vol.13
, Issue.8
, pp. 715-724
-
-
Gaskin, D.J.1
Richard, P.2
-
8
-
-
84895862975
-
-
http://www.thepharmaletter.com/file/108598/anti-inflammatory- therapeutics-market-to-grow-to859-billion-in-2017.htm
-
-
-
-
9
-
-
44649102705
-
Synthesis and analgesic/anti-inflammatory evaluation of fused heterocyclic ring systems incorporating phenylsulfonyl moiety
-
DOI 10.1016/j.bmc.2008.05.011, PII S0968089608004306
-
M.R. Shaaban, T.S. Saleh, A.S. Mayhoub, A. Mansour, and A.M. Farag Synthesis and analgesic/anti-inflammatory evaluation of fused heterocyclic ring systems incorporating phenylsulfonyl moiety Bioorg. Med. Chem. 16 12 2008 6344 6352 (Pubitemid 351783421)
-
(2008)
Bioorganic and Medicinal Chemistry
, vol.16
, Issue.12
, pp. 6344-6352
-
-
Shaaban, M.R.1
Saleh, T.S.2
Mayhoub, A.S.3
Mansour, A.4
Farag, A.M.5
-
10
-
-
26844465915
-
The coxib NSAIDs: Potential clinical and pharmacologic importance in veterinary medicine
-
DOI 10.1892/0891-6640(2005)19[633:TCNPCA]2.0.CO;2
-
M.S. Bergh, and S.C. Budsberg The coxib NSAIDs: potential clinical and pharmacologic importance in veterinary medicine J. Vet. Intern. Med. 19 5 2005 633 643 (Pubitemid 41452333)
-
(2005)
Journal of Veterinary Internal Medicine
, vol.19
, Issue.5
, pp. 633-643
-
-
Bergh, M.S.1
Budsberg, S.C.2
-
11
-
-
0008155098
-
-
fifth ed. Lippincott Williams and Wilkins Philadelphia, PA
-
B. Feldman, J. Zinkl, and N. Jain Veterinary Hematology fifth ed. 2000 Lippincott Williams and Wilkins Philadelphia, PA 213
-
(2000)
Veterinary Hematology
, pp. 213
-
-
Feldman, B.1
Zinkl, J.2
Jain, N.3
-
13
-
-
77955674352
-
Non-steroidal anti-inflammatory drugs: An overview of cardiovascular risks
-
I.L. Meek, M.A.F.J. Van de Laar, and H.E. Vonkeman Non-steroidal anti-inflammatory drugs: an overview of cardiovascular risks Pharmaceuticals 3 2010 2146 2162
-
(2010)
Pharmaceuticals
, vol.3
, pp. 2146-2162
-
-
Meek, I.L.1
Van De Laar, M.A.F.J.2
Vonkeman, H.E.3
-
14
-
-
34548127718
-
Withdrawal of COX-2 selective inhibitors rofecoxib and valdecoxib: Impact on NSAID and gastroprotective drug prescribing and utilization
-
DOI 10.1185/030079907X210561
-
S.X. Sun, K.Y. Lee, C.T. Bertram, and J.L. Goldstein Withdrawal of COX-2 selective inhibitors rofecoxib and valdecoxib: impact on NSAID and gastroprotective drug prescribing and utilization Curr. Med. Res. Opin. 23 8 2007 1859 1866 (Pubitemid 47300385)
-
(2007)
Current Medical Research and Opinion
, vol.23
, Issue.8
, pp. 1859-1866
-
-
Sun, S.X.1
Lee, K.Y.2
Bertram, C.T.3
Goldstein, J.L.4
-
15
-
-
77950355734
-
Anti-inflammatory agents: Present and future
-
C.A. Dinarello Anti-inflammatory agents: present and future Cell 140 6 2010 935 950
-
(2010)
Cell
, vol.140
, Issue.6
, pp. 935-950
-
-
Dinarello, C.A.1
-
16
-
-
84879843657
-
Heterocyclic chemistry of benzimidazoles and potential activities of derivatives
-
R.G. Ingle, and D.D. Magar Heterocyclic chemistry of benzimidazoles and potential activities of derivatives Int. J. Drug. Res. Technol. 1 1 2011 26 32
-
(2011)
Int. J. Drug. Res. Technol.
, vol.1
, Issue.1
, pp. 26-32
-
-
Ingle, R.G.1
Magar, D.D.2
-
17
-
-
0001062675
-
Acidity constants of some arylimidazoles and their cations
-
H. Walba, and R.W. Isensee Acidity constants of some arylimidazoles and their cations J. Org. Chem. 26 1961 2789 2791
-
(1961)
J. Org. Chem.
, vol.26
, pp. 2789-2791
-
-
Walba, H.1
Isensee, R.W.2
-
18
-
-
0015237292
-
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
-
J.R. Vane Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs Nat. New Biol. 231 1971 232 235
-
(1971)
Nat. New Biol.
, vol.231
, pp. 232-235
-
-
Vane, J.R.1
-
19
-
-
0015237275
-
Aspirin selectively inhibits prostaglandin production in human platelets
-
J.B. Smith, and A.L. Willis Aspirin selectively inhibits prostaglandin production in human platelets Nat. New Biol. 231 1971 235 237
-
(1971)
Nat. New Biol.
, vol.231
, pp. 235-237
-
-
Smith, J.B.1
Willis, A.L.2
-
20
-
-
0025754779
-
Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
-
W.L. Xie, J.G. Chipman, D.L. Robertson, R.L. Erikson, and D.L. Simmons Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing Proc. Natl. Acad. Sci. U.S.A. 88 1991 2692 2696 (Pubitemid 21916484)
-
(1991)
Proceedings of the National Academy of Sciences of the United States of America
, vol.88
, Issue.7
, pp. 2692-2696
-
-
Xie, W.1
Chipman, J.G.2
Robertson, D.L.3
Erikson, R.L.4
Simmons, D.L.5
-
21
-
-
0025871150
-
TIS10, a phorbol ester tumor promoter/inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue
-
D.A. Kubuju, B.S. Fletcher, B.C. Varnum, R.A. Lim, and H.R. Herschman TIS10, a phorbol ester tumor promoter/inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue J. Biol. Chem. 266 1991 12866 12872
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 12866-12872
-
-
Kubuju, D.A.1
Fletcher, B.S.2
Varnum, B.C.3
Lim, R.A.4
Herschman, H.R.5
-
24
-
-
0037294820
-
Design, synthesis and biological evaluation of benzimidazole/ benzothiazole and benzoxazole derivatives as cyclooxygenase inhibitors
-
DOI 10.1016/S0960-894X(02)01006-5, PII S0960894X02010065
-
R. Paramashivappa, P.P. Kumar, P.V.S. Rao, and A.S. Rao Design, synthesis and biological evaluation of benzimidazole/benzothiazole and benzoxazole derivatives as cyclooxygenase inhibitors Bioorg. Med. Chem. Lett. 13 4 2003 657 660 (Pubitemid 36298462)
-
(2003)
Bioorganic and Medicinal Chemistry Letters
, vol.13
, Issue.4
, pp. 657-660
-
-
Paramashivappa, R.1
Phani Kumar, P.2
Subba Rao, P.V.3
Srinivasa Rao, A.4
-
25
-
-
13144260638
-
Pharmacological analysis of cyclooxygenase-1 in inflammation
-
DOI 10.1073/pnas.95.22.13313
-
C.J. Smith, Y. Zhang, C.M. Koboldt, J. Muhammad, B.S. Zweifel, A. Shaffer, J.J. Talley, J.L. Masferrer, K. Seibert, and P.C. Isakson Pharmacological analysis of cyclooxygenase-1 in inflammation Proc. Natl. Acad. Sci. U.S.A. 95 1998 13313 13318 (Pubitemid 28509568)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.22
, pp. 13313-13318
-
-
Smith, C.J.1
Zhang, Y.2
Koboldt, C.M.3
Muhammad, J.4
Zweifel, B.S.5
Shaffer, A.6
Talley, J.J.7
Masferrer, J.L.8
Seibert, K.9
Isakson, P.C.10
-
26
-
-
4644266613
-
The role of the vanilloid (capsaicin) receptor (TRPV1) in physiology and pathology
-
DOI 10.1016/j.ejphar.2004.07.037, PII S0014299904007460
-
I. Nagy, P. Santha, G. Jancso, and L. Urban The role of the vanilloid (capsaicin) receptor (TRPV1) in physiology and pathology Eur. J. Pharmacol. 500 1-3 2004 351 369 (Pubitemid 39304020)
-
(2004)
European Journal of Pharmacology
, vol.500
, pp. 351-369
-
-
Nagy, I.1
Santha, P.2
Jancso, G.3
Urban, L.4
-
27
-
-
0033984992
-
The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1)
-
D. Smart, M.J. Gunthrope, J.C. Jerman, S. Nasir, J. Gray, A.I. Muir, J.K. Chambers, A.D. Randal, and J.B. Davis The endogenous lipid anandamide is a full agonist at the human vanilloid receptor (hVR1) Br. J. Pharm. 129 2 2000 227 230 (Pubitemid 30072640)
-
(2000)
British Journal of Pharmacology
, vol.129
, Issue.2
, pp. 227-230
-
-
Smart, D.1
Gunthorpe, M.J.2
Jerman, J.C.3
Nasir, S.4
Gray, J.5
Muir, A.I.6
Chambers, J.K.7
Randall, A.D.8
Davis, J.B.9
-
28
-
-
0004906771
-
Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances
-
DOI 10.1073/pnas.97.11.6155
-
S.W. Hwang, H. Cho, J. Kwak, S.Y. Lee, C.J. Kang, J. Jung, S. Cho, K.H. Min, Y.G. Suh, D. Kim, and U. Oh Direct activation of capsaicin receptors by products of lipoxygenases: endogenous capsaicin-like substances Proc. Natl. Acad. Sci. U.S.A. 97 2000 6155 6160 (Pubitemid 30367539)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.11
, pp. 6155-6160
-
-
Hwang, S.W.1
Cho, H.2
Kwak, J.3
Lee, S.-Y.4
Kang, C.-J.5
Jung, J.6
Cho, S.7
Min, K.H.8
Suh, Y.-G.9
Kim, D.10
Oh, U.11
-
29
-
-
0034926291
-
The vanilloid receptor: A molecular gateway to the pain pathway
-
DOI 10.1146/annurev.neuro.24.1.487
-
M.J. Caterina, and D. Julius The vanilloid receptor: a molecular gateway to the pain pathway Annu. Rev. Neurosci. 24 2001 487 517 (Pubitemid 32695237)
-
(2001)
Annual Review of Neuroscience
, vol.24
, pp. 487-517
-
-
Caterina, M.J.1
Julius, D.2
-
30
-
-
2442642767
-
Vanilloid receptor TRPV1 antagonists as the next generation of painkillers. Are we putting the cart before the horse?
-
DOI 10.1021/jm030560j
-
A. Szallasi, and G. Appendino Vanilloid receptor TRPV1 antagonists as the next generation of painkillers. Are we putting the cart before the horse J. Med. Chem. 47 11 2004 2717 2723 (Pubitemid 38656724)
-
(2004)
Journal of Medicinal Chemistry
, vol.47
, Issue.11
, pp. 2717-2723
-
-
Szallasi, A.1
Appendino, G.2
-
31
-
-
8844256161
-
Current perspectives on the therapeutic utility of VR1 antagonists
-
K.J. Valenzano, and Q. Sun Current perspectives on the therapeutic utility of VR1 antagonists Curr. Med. Chem. 11 2004 3185 3202 (Pubitemid 39534745)
-
(2004)
Current Medicinal Chemistry
, vol.11
, Issue.24
, pp. 3185-3202
-
-
Valenzano, K.J.1
Sun, Q.2
-
32
-
-
13444270763
-
The therapeutic potential of TRPV1 (VR1) antagonists: Clinical answers await
-
DOI 10.1016/j.ddstr.2004.08.020, PII S1740677304000233
-
H.K. Rami, and M.J. Gunthorpe The therapeutic potential of TRPV1 (VR1) antagonists: clinical answers await Drug Discov. Today: Ther. Strateg. 1 2004 97 104 (Pubitemid 40208014)
-
(2004)
Drug Discovery Today: Therapeutic Strategies
, vol.1
, Issue.1
, pp. 97-104
-
-
Rami, H.K.1
Gunthorpe, M.J.2
-
34
-
-
33745136758
-
Design of potent, orally available antagonists of the transient receptor potential vanilloid 1. Structure-activity relationships of 2-piperazin-1-yl-1H- benzimidazoles
-
DOI 10.1021/jm060065y
-
V.I. Ognyanov, C. Balan, A.W. Bannon, Y. Bo, C. Dominguez, C. Fotsch, V.K. Gore, L. Klionsky, V.V. Ma, Y.X. Qian, R. Tamir, X. Wang, N. Xi, S. Xu, D. Zhu, N.R. Gavva, J.J. Treanor, and M.H. Norman Design of potent, orally available antagonists of the transient receptor potential vanilloid 1. Structure-activity relationships of 2-piperazin-1-yl-1H benzimidazoles J. Med. Chem. 49 12 2006 3719 3742 (Pubitemid 43902478)
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.12
, pp. 3719-3742
-
-
Ognyanov, V.I.1
Balan, C.2
Bannon, A.W.3
Bo, Y.4
Dominguez, C.5
Fotsch, C.6
Gore, V.K.7
Klionsky, L.8
Ma, V.V.9
Qian, Y.-X.10
Tamir, R.11
Wang, X.12
Xi, N.13
Xu, S.14
Zhu, D.15
Gavva, N.R.16
Treanor, J.J.S.17
Norman, M.H.18
-
35
-
-
33746636903
-
The search for novel TRPV1-antagonists: From carboxamides to benzimidazoles and indazolones
-
DOI 10.1016/j.bmcl.2006.03.004, PII S0960894X06002836
-
S.R. Fletcher, E. McIver, S. Lewis, F. Burkamp, C. Leech, G. Mason, S. Boyce, D. Morrison, G. Richards, K. Sutton, and A.B. Jones The search for novel TRPV1-antagonists: from carboxamides to benzimidazoles and indazolones Bioorg. Med. Chem. Lett. 16 2006 2872 2876 (Pubitemid 44316655)
-
(2006)
Bioorganic and Medicinal Chemistry Letters
, vol.16
, Issue.11
, pp. 2872-2876
-
-
Robert Fletcher, S.1
McIver, E.2
Lewis, S.3
Burkamp, F.4
Leech, C.5
Mason, G.6
Boyce, S.7
Morrison, D.8
Richards, G.9
Sutton, K.10
Brian Jones, A.11
-
36
-
-
34447542824
-
Targeting cannabinoid agonists for inflammatory and neuropathic pain
-
DOI 10.1517/13543784.16.7.951
-
Y. Cheng, and S.A. Hitchcock Targeting cannabinoid agonists for inflammatory and neuropathic pain Expert Opin. Invest. Drugs 16 7 2007 951 965 (Pubitemid 47074154)
-
(2007)
Expert Opinion on Investigational Drugs
, vol.16
, Issue.7
, pp. 951-965
-
-
Cheng, Y.1
Hitchcock, S.A.2
-
37
-
-
79959913605
-
Optimisation of a novel series of selective CNS penetrant CB2 agonists
-
C. Watson, D.R. Owen, D. Harding, K. Kon-I, M.L. Lewis, H.J. Mason, M. Matsumizu, T. Mukaiyama, M. Rodriguez-Lens, A. Shima, M. Takeuchi, I. Tran, and T. Young Optimisation of a novel series of selective CNS penetrant CB2 agonists Bioorg. Med. Chem. Lett. 21 2011 4284 4287
-
(2011)
Bioorg. Med. Chem. Lett.
, vol.21
, pp. 4284-4287
-
-
Watson, C.1
Owen, D.R.2
Harding, D.3
Kon-I, K.4
Lewis, M.L.5
Mason, H.J.6
Matsumizu, M.7
Mukaiyama, T.8
Rodriguez-Lens, M.9
Shima, A.10
Takeuchi, M.11
Tran, I.12
Young, T.13
-
38
-
-
84655162746
-
5-Sulfonyl-benzimidazoles as selective CB2 agonists-Part 2
-
H.J.M. Gijsen, M.A.J. De Cleyn, M. Surkyn, G.R.E. Van Lommen, B.M.P. Verbist, M.J.M.A. Nijsen, T. Meert, J.V. Wauwe, and J. Aerssens 5-Sulfonyl-benzimidazoles as selective CB2 agonists-Part 2 Bioorg. Med. Chem. Lett. 22 2012 547 552
-
(2012)
Bioorg. Med. Chem. Lett.
, vol.22
, pp. 547-552
-
-
Gijsen, H.J.M.1
De Cleyn, M.A.J.2
Surkyn, M.3
Van Lommen, G.R.E.4
Verbist, B.M.P.5
Nijsen, M.J.M.A.6
Meert, T.7
Wauwe, J.V.8
Aerssens, J.9
-
40
-
-
0036267811
-
Kinins, the long march - A personal view
-
DOI 10.1016/S0008-6363(02)00284-5, PII S0008636302002845
-
E.G. Erdos Kinins, the long march-a personal view Cardiovasc. Res. 54 3 2002 485 491 (Pubitemid 34595405)
-
(2002)
Cardiovascular Research
, vol.54
, Issue.3
, pp. 485-491
-
-
Erdos, E.G.1
-
42
-
-
0018995127
-
Pharmacology of bradykinin and related kinins
-
D. Regoli, and J. Barabe Pharmacology of bradykinin and related kinins Pharmacol. Rev. 32 1 1980 1 46
-
(1980)
Pharmacol. Rev.
, vol.32
, Issue.1
, pp. 1-46
-
-
Regoli, D.1
Barabe, J.2
-
43
-
-
51349162467
-
1 receptor antagonists
-
1 receptor antagonists Bioorg. Med. Chem. Lett. 18 2008 5027 5031
-
(2008)
Bioorg. Med. Chem. Lett.
, vol.18
, pp. 5027-5031
-
-
Guo, Q.1
Chandrasekhar, J.2
Ihle, D.3
Wustrow, D.J.4
Chenard, B.L.5
Krause, J.E.6
Hutchison, A.7
Alderman, D.8
Cheng, C.9
Cortright, D.10
Broom, D.11
Kershaw, M.T.12
Simmermacher-Mayer, J.13
Peng, Y.14
Hodgetts, K.J.15
-
44
-
-
74049108918
-
Novel small molecule bradykinin B1 receptor antagonists. Part 2: 5-membered diaminoheterocycles
-
G. Zischinsky, R. Stragies, M. Schaudt, J.R. Pfeifer, C. Gibson, E. Locardi, D. Scharn, U. Richter, H. Kalkhof, K. Dinkel, and K. Schnatbaum Novel small molecule bradykinin B1 receptor antagonists. Part 2: 5-membered diaminoheterocycles Bioorg. Med. Chem. Lett. 20 2010 1229 1232
-
(2010)
Bioorg. Med. Chem. Lett.
, vol.20
, pp. 1229-1232
-
-
Zischinsky, G.1
Stragies, R.2
Schaudt, M.3
Pfeifer, J.R.4
Gibson, C.5
Locardi, E.6
Scharn, D.7
Richter, U.8
Kalkhof, H.9
Dinkel, K.10
Schnatbaum, K.11
-
45
-
-
35448943946
-
Inflammatory molecules: A target for treatment of systemic autoimmune diseases
-
DOI 10.1016/j.autrev.2007.03.001, PII S1568997207000699, New Strategies for the Control of Inflmmatory Diseases
-
A. Tincani, L. Andreoli, C. Bazzani, D. Bosiso, and S. Sozzani Inflammatory molecules: a target for treatment of systemic autoimmune diseases Autoimmun. Rev. 7 1 2007 1 7 (Pubitemid 47633384)
-
(2007)
Autoimmunity Reviews
, vol.7
, Issue.1
, pp. 1-7
-
-
Tincani, A.1
Andreoli, L.2
Bazzani, C.3
Bosiso, D.4
Sozzani, S.5
-
46
-
-
33750514341
-
Inhibition of Tpl2 kinase and TNFα production with quinoline-3-carbonitriles for the treatment of rheumatoid arthritis
-
DOI 10.1016/j.bmcl.2006.08.102, PII S0960894X06010110
-
Y. Hu, N. Gren, L.K. Gavrin, K. Janz, N. Kaila, and H.Q. Li Inhibition of Tpl2 kinase and TNFα production with quinoline-3-carbonitriles for the treatment of rheumatoid arthritis Bioorg. Med. Chem. Lett. 16 2006 6067 6072 (Pubitemid 44667801)
-
(2006)
Bioorganic and Medicinal Chemistry Letters
, vol.16
, Issue.23
, pp. 6067-6072
-
-
Hu, Y.1
Green, N.2
Gavrin, L.K.3
Janz, K.4
Kaila, N.5
Li, H.-Q.6
Thomason, J.R.7
Cuozzo, J.W.8
Hall, J.P.9
Hsu, S.10
Nickerson-Nutter, C.11
Telliez, J.-B.12
Lin, L.-L.13
Tam, S.14
-
47
-
-
0028605318
-
Protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
J.C. Lee, J.T. Laydon, P.C. McDonnell, T.F. Gallagher, S. Kumar, and D.A. Green Protein kinase involved in the regulation of inflammatory cytokine biosynthesis Nature 372 2002 739 746
-
(2002)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
Laydon, J.T.2
McDonnell, P.C.3
Gallagher, T.F.4
Kumar, S.5
Green, D.A.6
-
49
-
-
20244384283
-
Design of potent and selective 2-aminobenzimidazole-based p38α MAP kinase inhibitors with excellent in vivo efficacy
-
DOI 10.1021/jm048978k
-
A.D. Dios, C.B. Shih, L.D. Uralde, C. Sanchez, M.D. Prado, and M.M. Cabrejas Design of potent and selective 2-aminobenzimidazole-based p38α MAP kinase inhibitors with excellent in vivo efficacy J. Med. Chem. 48 2005 2270 2273 (Pubitemid 40516420)
-
(2005)
Journal of Medicinal Chemistry
, vol.48
, Issue.7
, pp. 2270-2273
-
-
De Dios, A.1
Shih, C.2
Lopez De Uralde, B.L.3
Sanchez, C.4
Del Prado, M.5
Martin Cabrejas, L.M.6
Pleite, S.7
Blanco-Urgoiti, J.8
Lorite, M.J.9
Nevill Jr., C.R.10
Bonjouklian, R.11
York, J.12
Vieth, M.13
Wang, Y.14
Magnus, N.15
Campbell, R.M.16
Anderson, B.D.17
McCann, D.J.18
Giera, D.D.19
Lee, P.A.20
Schultz, R.M.21
Li, L.C.22
Johnson, L.M.23
Wolos, J.A.24
more..
-
50
-
-
33750531634
-
The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck)
-
DOI 10.1016/j.bmcl.2006.08.132, PII S0960894X06010444
-
M. Sabat, J.C. VanRens, M.J. Laufersweiler, T.A. Brugel, J. Maier, A. Golebiowski, B. De, V. Easwaran, L.C. Hsieh, R.L. Walter, M.J. Mekel, A. Evdokimov, and M.J. Janusz The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck) Bioorg. Med. Chem. Lett. 16 2006 5973 5977 (Pubitemid 44667817)
-
(2006)
Bioorganic and Medicinal Chemistry Letters
, vol.16
, Issue.23
, pp. 5973-5977
-
-
Sabat, M.1
VanRens, J.C.2
Laufersweiler, M.J.3
Brugel, T.A.4
Maier, J.5
Golebiowski, A.6
De, B.7
Easwaran, V.8
Hsieh, L.C.9
Walter, R.L.10
Mekel, M.J.11
Evdokimov, A.12
Janusz, M.J.13
-
51
-
-
41149118544
-
Structure-based design of novel 2-amino-6-phenyl-pyrimido[5′, 4′:5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): Synthesis, SAR, and in vivo anti-inflammatory activity
-
DOI 10.1021/jm701095m
-
M.W. Martin, J. Newcomb, J.J. Nunes, C. Boucher, L. Chai, L.F. Epstein, T. Faust, S. Flores, P. Gallant, A. Gore, Y. Gu, F. Hsieh, X. Huang, J.L. Kim, S. Middleton, K. Morgenstern, A. Oliveira-dos-Santos, V.F. Patel, D. Powers, P. Rose, Y. Tudor, S.M. Turci, A.A. Welcher, D. Zack, H. Zhao, L. Zhu, X. Zhu, C. Ghiron, M. Ermann, D. Johnston, and C.G. Saluste Structure-based design of novel 2-amino-6-phenyl-pyrimido[5′,4′:5,6]pyrimido[1,2-a]benzimidazol- 5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): synthesis, SAR and in vivo anti-inflammatory activity J. Med. Chem. 51 6 2008 1637 1648 (Pubitemid 351438847)
-
(2008)
Journal of Medicinal Chemistry
, vol.51
, Issue.6
, pp. 1637-1648
-
-
Martin, M.W.1
Newcomb, J.2
Nunes, J.J.3
Boucher, C.4
Chai, L.5
Epstein, L.F.6
Faust, T.7
Flores, S.8
Gallant, P.9
Gore, A.10
Gu, Y.11
Hsieh, F.12
Huang, X.13
Kim, J.L.14
Middleton, S.15
Morgenstern, K.16
Oliveira-dos-Santos, A.17
Patel, V.F.18
Powers, D.19
Rose, P.20
Tudor, Y.21
Turci, S.M.22
Welcher, A.A.23
Zack, D.24
Zhao, H.25
Zhu, L.26
Zhu, X.27
Ghiron, C.28
Ermann, M.29
Johnston, D.30
Saluste, C.-G.P.31
more..
-
52
-
-
68949122712
-
Disubstituted pyrimidines as Lck inhibitors
-
J.A. Hunt, R.T. Beresis, J.L. Goulet, M.A. Holmes, X.J. Hong, E. Kovacs, S.G. Mills, R.D. Ruzek, F. Wong, J.D. Hermes, Y. Park, S.P. Salowe, L.M. Sonatore, L. Wu, A. Woods, D.M. Zaller, and P.J. Sinclair Disubstituted pyrimidines as Lck inhibitors Bioorg. Med. Chem. Lett. 19 2009 5440 5443
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 5440-5443
-
-
Hunt, J.A.1
Beresis, R.T.2
Goulet, J.L.3
Holmes, M.A.4
Hong, X.J.5
Kovacs, E.6
Mills, S.G.7
Ruzek, R.D.8
Wong, F.9
Hermes, J.D.10
Park, Y.11
Salowe, S.P.12
Sonatore, L.M.13
Wu, L.14
Woods, A.15
Zaller, D.M.16
Sinclair, P.J.17
-
53
-
-
77952109517
-
Discovery of anti-inflammatory clinical candidate E6201, inspired from resorcylic lactone LL-Z1640-2, III
-
Y. Shen, R. Boivin, N. Yoneda, H. Du, S. Schiller, T. Matsushima, M. Goto, H. Shirota, F. Gusovsky, C. Lemelin, Y. Jiang, Z. Zhang, R. Pelletier, M. Ikemori-Kawada, Y. Kawakami, A. Inoue, M. Schnaderbeck, and Y. Wang Discovery of anti-inflammatory clinical candidate E6201, inspired from resorcylic lactone LL-Z1640-2, III Bioorg. Med. Chem. Lett. 20 10 2010 3155 3157
-
(2010)
Bioorg. Med. Chem. Lett.
, vol.20
, Issue.10
, pp. 3155-3157
-
-
Shen, Y.1
Boivin, R.2
Yoneda, N.3
Du, H.4
Schiller, S.5
Matsushima, T.6
Goto, M.7
Shirota, H.8
Gusovsky, F.9
Lemelin, C.10
Jiang, Y.11
Zhang, Z.12
Pelletier, R.13
Ikemori-Kawada, M.14
Kawakami, Y.15
Inoue, A.16
Schnaderbeck, M.17
Wang, Y.18
-
54
-
-
38749113897
-
What's all the FLAP about? 5-lipoxygenase-activating protein inhibitors for inflammatory diseases
-
J.F. Evans, A.D. Ferguson, R.T. Mosley, and J.H. Hutchinson What's all the FLAP about? 5-lipoxygenase-activating protein inhibitors for inflammatory diseases Trends Pharmacol. Sci. 29 2 2008 72 78
-
(2008)
Trends Pharmacol. Sci.
, vol.29
, Issue.2
, pp. 72-78
-
-
Evans, J.F.1
Ferguson, A.D.2
Mosley, R.T.3
Hutchinson, J.H.4
-
55
-
-
70349648499
-
5-Lipoxygenase-activating protein inhibitors: Development of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl] -5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid (AM103)
-
J.H. Hutchinson, Y. Li, J.M. Arruda, C. Baccei, G. Bain, C. Chapman, L. Correa, J. Darlington, C.D. King, C. Lee, D. Lorrain, P. Prodanovich, H. Rong, A. Santini, N. Stock, P. Prasit, and J.F. Evans 5-Lipoxygenase-activating protein inhibitors: development of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy- pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2, 2-dimethyl-propionic acid (AM103) J. Med. Chem. 52 19 2009 5803 5815
-
(2009)
J. Med. Chem.
, vol.52
, Issue.19
, pp. 5803-5815
-
-
Hutchinson, J.H.1
Li, Y.2
Arruda, J.M.3
Baccei, C.4
Bain, G.5
Chapman, C.6
Correa, L.7
Darlington, J.8
King, C.D.9
Lee, C.10
Lorrain, D.11
Prodanovich, P.12
Rong, H.13
Santini, A.14
Stock, N.15
Prasit, P.16
Evans, J.F.17
-
56
-
-
72049104422
-
5-Lipoxygenase-activating protein inhibitors. Part 2: 3-{5-((S)-1-Acetyl-2,3-dihydro-1H-indol-2-ylmethoxy)-3-tert-butylsulfanyl-1-[4- (5-methoxy-pyrimidin-2-yl)-benzyl]-1H-indol-2-yl}-2,2-dimethyl-propionic acid (AM679)-a potent FLAP inhibitor
-
N. Stock, C. Baccei, G. Bain, A. Broadhead, C. Chapman, J. Darlington, C. King, C. Lee, Y. Li, D.S. Lorrain, P. Prodanovich, H. Rong, A. Santini, J. Zunic, J.F. Evans, J.H. Hutchinson, and P. Prasit 5-Lipoxygenase-activating protein inhibitors. Part 2: 3-{5-((S)-1-Acetyl-2,3-dihydro-1H-indol-2-ylmethoxy) -3-tert-butylsulfanyl-1-[4-(5-methoxy-pyrimidin-2-yl)-benzyl]-1H-indol-2-yl}-2, 2-dimethyl-propionic acid (AM679)-a potent FLAP inhibitor Bioorg. Med. Chem. Lett. 20 1 2010 213 217
-
(2010)
Bioorg. Med. Chem. Lett.
, vol.20
, Issue.1
, pp. 213-217
-
-
Stock, N.1
Baccei, C.2
Bain, G.3
Broadhead, A.4
Chapman, C.5
Darlington, J.6
King, C.7
Lee, C.8
Li, Y.9
Lorrain, D.S.10
Prodanovich, P.11
Rong, H.12
Santini, A.13
Zunic, J.14
Evans, J.F.15
Hutchinson, J.H.16
Prasit, P.17
-
57
-
-
77955427072
-
5-Lipoxygenase-activating protein inhibitors. Part 3: 3-{3-tert-butylsulfanyl-1-[4-(5-methoxy-pyrimidin-2-yl)-benzyl] -5-(5-methyl-pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropionic acid (AM643)-a potent FLAP inhibitor suitable for topical administration
-
N. Stock, C. Baccei, G. Bain, C. Chapman, L. Correa, J. Darlington, C. King, C. Lee, D.S. Lorrain, P. Prodanovich, A. Santini, K. Schaab, J.F. Evans, J.H. Hutchinson, and P. Prasit 5-Lipoxygenase-activating protein inhibitors. Part 3: 3-{3-tert-butylsulfanyl-1-[4-(5-methoxy-pyrimidin-2-yl)-benzyl]-5-(5- methyl-pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropionic acid (AM643)-a potent FLAP inhibitor suitable for topical administration Bioorg. Med. Chem. Lett. 20 15 2010 4598 4601
-
(2010)
Bioorg. Med. Chem. Lett.
, vol.20
, Issue.15
, pp. 4598-4601
-
-
Stock, N.1
Baccei, C.2
Bain, G.3
Chapman, C.4
Correa, L.5
Darlington, J.6
King, C.7
Lee, C.8
Lorrain, D.S.9
Prodanovich, P.10
Santini, A.11
Schaab, K.12
Evans, J.F.13
Hutchinson, J.H.14
Prasit, P.15
-
58
-
-
82555168047
-
5-Lipoxygenase-activating protein (FLAP) inhibitors. Part 4: Development of 3-[3-tert-butylsulfanyl-1-[4-(6-ethoxypyridin-3-yl)benzyl]-5-(5- methylpyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropionic acid (AM803), a potent, oral, once daily FLAP inhibitor
-
N.S. Stock, G. Bain, J. Zunic, Y. Li, J. Ziff, J. Roppe, A. Santini, J. Darlington, P. Prodanovich, C.D. King, C. Baccei, C. Lee, H. Rong, C. Chapman, A. Broadhead, D. Lorrain, L. Correa, J.H. Hutchinson, J.F. Evans, and P. Prasit 5-Lipoxygenase-activating protein (FLAP) inhibitors. Part 4: development of 3-[3-tert-butylsulfanyl-1-[4-(6-ethoxypyridin-3-yl)benzyl]-5-(5-methylpyridin-2- ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropionic acid (AM803), a potent, oral, once daily FLAP inhibitor J. Med. Chem. 54 23 2011 8013 8029
-
(2011)
J. Med. Chem.
, vol.54
, Issue.23
, pp. 8013-8029
-
-
Stock, N.S.1
Bain, G.2
Zunic, J.3
Li, Y.4
Ziff, J.5
Roppe, J.6
Santini, A.7
Darlington, J.8
Prodanovich, P.9
King, C.D.10
Baccei, C.11
Lee, C.12
Rong, H.13
Chapman, C.14
Broadhead, A.15
Lorrain, D.16
Correa, L.17
Hutchinson, J.H.18
Evans, J.F.19
Prasit, P.20
more..
-
59
-
-
84861573030
-
Identification of novel benzimidazole derivatives as inhibitors of leukotriene biosynthesis by virtual screening targeting 5-lipoxygenase- activating protein (FLAP)
-
E. Banoglu, B. Caliskan, S. Luderer, G. Eren, Y. Ozkan, W. Altenhofen, C. Weinigel, D. Barz, J. Gerstmeier, C. Pergola, and O. Werz Identification of novel benzimidazole derivatives as inhibitors of leukotriene biosynthesis by virtual screening targeting 5-lipoxygenase-activating protein (FLAP) Bioorg. Med. Chem. 20 2012 3728 3741
-
(2012)
Bioorg. Med. Chem.
, vol.20
, pp. 3728-3741
-
-
Banoglu, E.1
Caliskan, B.2
Luderer, S.3
Eren, G.4
Ozkan, Y.5
Altenhofen, W.6
Weinigel, C.7
Barz, D.8
Gerstmeier, J.9
Pergola, C.10
Werz, O.11
-
60
-
-
77950864109
-
Synthesis and pharmacological evaluation of novel 5-substituted-1- (phenylsulfonyl)-2-methylbenzimidazole derivatives as anti-inflammatory and analgesic agents
-
M. Gaba, D. Singh, S. Singh, V. Sharma, and P. Gaba Synthesis and pharmacological evaluation of novel 5-substituted-1-(phenylsulfonyl)-2- methylbenzimidazole derivatives as anti-inflammatory and analgesic agents Eur. J. Med. Chem. 45 6 2010 2245 2249
-
(2010)
Eur. J. Med. Chem.
, vol.45
, Issue.6
, pp. 2245-2249
-
-
Gaba, M.1
Singh, D.2
Singh, S.3
Sharma, V.4
Gaba, P.5
-
61
-
-
84895865803
-
Evaluation of analgesic and anti-inflammatory activities of N-mannich bases of substituted 2-mercapto-1H-benzimidazoles
-
G.M. Rao, Y.N. Reddy, and B.V. Kumar Evaluation of analgesic and anti-inflammatory activities of N-mannich bases of substituted 2-mercapto-1H-benzimidazoles Int. J. Appl. Biol. Pharm. Technol. 4 1 2013 38 46
-
(2013)
Int. J. Appl. Biol. Pharm. Technol.
, vol.4
, Issue.1
, pp. 38-46
-
-
Rao, G.M.1
Reddy, Y.N.2
Kumar, B.V.3
-
62
-
-
85012047178
-
Synthesis and evaluation of anti-inflammatory, antioxidant and antimicrobial activities of densely functionalized novel benzo-[d]-imidazolyl tetrahydropyridine carboxylates
-
in press
-
A. Ravindernath, and M.S. Reddy Synthesis and evaluation of anti-inflammatory, antioxidant and antimicrobial activities of densely functionalized novel benzo-[d]-imidazolyl tetrahydropyridine carboxylates Arab. J. Chem. 2013 in press
-
(2013)
Arab. J. Chem.
-
-
Ravindernath, A.1
Reddy, M.S.2
-
63
-
-
84873720775
-
Regioselective synthesis of isoxazole-mercapto benzimidazole hybrids and their in vivo analgesic and anti-inflammatory activity studies
-
S. Kankala, R.K. Kankala, P. Gundepaka, N. Thota, S. Nerella, M.R. Gangula, H. Guguloth, M. Kagga, R. Vadde, and C.S. Vasam Regioselective synthesis of isoxazole-mercapto benzimidazole hybrids and their in vivo analgesic and anti-inflammatory activity studies Bioorg. Med. Chem. Lett. 23 5 2013 1306 1309
-
(2013)
Bioorg. Med. Chem. Lett.
, vol.23
, Issue.5
, pp. 1306-1309
-
-
Kankala, S.1
Kankala, R.K.2
Gundepaka, P.3
Thota, N.4
Nerella, S.5
Gangula, M.R.6
Guguloth, H.7
Kagga, M.8
Vadde, R.9
Vasam, C.S.10
-
64
-
-
32844460667
-
Synthesis of 1-acyl-2-alkylthio-1,2,4-triazolobenzimidazoles with antifungal, anti-inflammatory and analgesic effects
-
B.G. Mohamed, A.M. Abdel-Alim, and M.A. Hussein Synthesis of 1-acyl-2-alkylthio-1,2,4-triazolobenzimidazoles with antifungal, anti-inflammatory and analgesic effects Acta Pharm. Res. 56 2006 31 48 (Pubitemid 43253971)
-
(2006)
Acta Pharmaceutica
, vol.56
, Issue.1
, pp. 31-48
-
-
Mohamed, B.G.1
Abdel-Alim, A.-A.M.2
Hussein, M.A.3
-
65
-
-
80052618216
-
Synthesis and biological evaluation of Mannich bases of benzimidazole derivatives
-
G. Mariappan, N.R. Bhuyan, P. Kumar, D. Kumar, and K. Murali Synthesis and biological evaluation of Mannich bases of benzimidazole derivatives Ind. J. Chem. 50B 2011 1216 1219
-
(2011)
Ind. J. Chem.
, vol.50 B
, pp. 1216-1219
-
-
Mariappan, G.1
Bhuyan, N.R.2
Kumar, P.3
Kumar, D.4
Murali, K.5
-
66
-
-
77949490147
-
In-vivo analgesic and anti-inflammatory activities of newly synthesized benzimidazole derivatives
-
K.C.S. Achar, K.M. Hosamani, and H.R. Seetharamareddy In-vivo analgesic and anti-inflammatory activities of newly synthesized benzimidazole derivatives Eur. J. Med. Chem. 45 5 2010 2048 2054
-
(2010)
Eur. J. Med. Chem.
, vol.45
, Issue.5
, pp. 2048-2054
-
-
Achar, K.C.S.1
Hosamani, K.M.2
Seetharamareddy, H.R.3
-
67
-
-
84874321287
-
Synthesis, anti-inflammatory and anti-oxidant activity of some substituted benzimidazole derivatives
-
S. Rajasekaran, G. Rao, and A. Chatterjee Synthesis, anti-inflammatory and anti-oxidant activity of some substituted benzimidazole derivatives Int. J. Drug Dev. Res. 4 3 2012 303 309
-
(2012)
Int. J. Drug Dev. Res.
, vol.4
, Issue.3
, pp. 303-309
-
-
Rajasekaran, S.1
Rao, G.2
Chatterjee, A.3
-
68
-
-
77949772550
-
Solvent free synthesis, anti-inflammatory and anticancer activity evaluation of tricyclic and tetracyclic benzimidazole derivatives
-
S.M. Sondhi, R. Rani, J. Singh, P. Roy, S.K. Agrawal, and A.K. Saxena Solvent free synthesis, anti-inflammatory and anticancer activity evaluation of tricyclic and tetracyclic benzimidazole derivatives Bioorg. Med. Chem. Lett. 20 7 2010 2306 2310
-
(2010)
Bioorg. Med. Chem. Lett.
, vol.20
, Issue.7
, pp. 2306-2310
-
-
Sondhi, S.M.1
Rani, R.2
Singh, J.3
Roy, P.4
Agrawal, S.K.5
Saxena, A.K.6
-
69
-
-
0036809043
-
Anti-inflammatory, analgesic and antiamoebic activity evaluation of pyrimido[1,6-a]benzimidazole derivatives synthesized by the reaction of ketoisothiocyanates with mono and diamines
-
DOI 10.1016/S0223-5234(02)01403-4, PII S0223523402014034
-
S.M. Sondhi, S. Rajvanshi, M. Johar, N. Bharti, A. Azam, and A.K. Singh Anti-inflammatory, analgesic and antiamoebic activity evaluation of pyrimido[1,6-a]benzimidazole derivatives synthesized by the reaction of ketoisothiocyanates with mono and diamines Eur. J. Med. Chem. 37 10 2002 835 843 (Pubitemid 35346544)
-
(2002)
European Journal of Medicinal Chemistry
, vol.37
, Issue.10
, pp. 835-843
-
-
Sondhi, S.M.1
Rajvanshi, S.2
Johar, M.3
Bharti, N.4
Azam, A.5
Singh, A.K.6
-
70
-
-
0027175627
-
Synthesis and antiinflammatory and analgesic properties of 2-amino-1H-benzimidazole and 1,2-dihydro-2-iminocycloheptimidazole derivatives
-
K. Taniguchi, S. Shigenaga, T. Ogahara, T. Fujitsu, and M. Matsuo Synthesis and anti- inflammatory and analgesic properties of 2-amino-1H-benzimidazole and 1,2-dihydro-2- iminocycloheptimidazole derivatives Chem. Pharm. Bull. 41 2 1993 301 309 (Pubitemid 23128192)
-
(1993)
Chemical and Pharmaceutical Bulletin
, vol.41
, Issue.2
, pp. 301-309
-
-
Taniguchi, K.1
Shigenaga, S.2
Ogahara, T.3
Fujitsu, T.4
Matsuo, M.5
-
71
-
-
75749088570
-
Structure-based design of benzimidazole sugar conjugates: Synthesis, SAR and in vivo anti-inflammatory and analgesic activities
-
A.O.H. El-Nezhawy, S.T. Gaballah, M.A.A. Radwan, A.R. Baiuomy, and O.M.E. Abdel-Salam Structure-based design of benzimidazole sugar conjugates: synthesis, SAR and in vivo anti-inflammatory and analgesic activities Med. Chem. 5 2009 558 569
-
(2009)
Med. Chem.
, vol.5
, pp. 558-569
-
-
El-Nezhawy, A.O.H.1
Gaballah, S.T.2
Radwan, M.A.A.3
Baiuomy, A.R.4
Abdel-Salam, O.M.E.5
-
72
-
-
84875210886
-
Design, synthesis and pharmacological evaluation of omeprazole-like agents with anti-inflammatory activity
-
A.O.H. El-Nezhawy, A.R. Biuomy, F.S. Hassan, A.K. Ismaiel, and H.A. Omar Design, synthesis and pharmacological evaluation of omeprazole-like agents with anti-inflammatory activity Bioorg. Med. Chem. 21 7 2013 1661 1670
-
(2013)
Bioorg. Med. Chem.
, vol.21
, Issue.7
, pp. 1661-1670
-
-
El-Nezhawy, A.O.H.1
Biuomy, A.R.2
Hassan, F.S.3
Ismaiel, A.K.4
Omar, H.A.5
-
73
-
-
85019232029
-
Synthesis and pharmacological evaluation of polyfunctional benzimidazole-NSAID chimeric molecules combining antiinflammatory, immunomodulatory and antioxidant activities
-
in press
-
Y. Bansal, and O. Silakari Synthesis and pharmacological evaluation of polyfunctional benzimidazole-NSAID chimeric molecules combining antiinflammatory, immunomodulatory and antioxidant activities Arch. Pharm. Res. 2013 in press
-
(2013)
Arch. Pharm. Res.
-
-
Bansal, Y.1
Silakari, O.2
-
74
-
-
84890800650
-
Design, synthesis and molecular docking of some new 1,2,4- triazolobenzimidazol-3-yl acetohydrazide derivatives with anti-inflammatory analgesic activities
-
A.F. Mohammed, S.G. Abdel-Moty, M.A. Hussein, and A.M. Abdel-Alim Design, synthesis and molecular docking of some new 1,2,4-triazolobenzimidazol-3-yl acetohydrazide derivatives with anti-inflammatory analgesic activities Arch. Pharm. Res. 36 12 2013 1465 1479
-
(2013)
Arch. Pharm. Res.
, vol.36
, Issue.12
, pp. 1465-1479
-
-
Mohammed, A.F.1
Abdel-Moty, S.G.2
Hussein, M.A.3
Abdel-Alim, A.M.4
|