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Volumn 5, Issue JAN, 2014, Pages

TWEAK/Fn14 axis: A promising target for the treatment of cardiovascular diseases

Author keywords

Atherosclerosis; Biomarker; Stroke; TNF superfamily; TWEAK

Indexed keywords

BIOLOGICAL MARKER; CD40 LIGAND; CYTOKINE RECEPTOR; FIBROBLAST GROWTH FACTORINDUCIBLE MOLECULE 14; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOTOXIN BETA RECEPTOR; METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; OSTEOCLAST DIFFERENTIATION FACTOR; PLASMINOGEN ACTIVATOR INHIBITOR 1; STRESS ACTIVATED PROTEIN KINASE 1; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR; TWEAK; UNCLASSIFIED DRUG;

EID: 84895558806     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2014.00003     Document Type: Article
Times cited : (59)

References (127)
  • 1
    • 0036162436 scopus 로고    scopus 로고
    • The molecular architecture of the TNF superfamily
    • doi:10.1016/S0968-0004(01)01995-8
    • Bodmer JL, Schneider P, Tschopp J. The molecular architecture of the TNF superfamily. Trends Biochem Sci (2002) 27:19-26. doi:10.1016/S0968-0004(01)01995-8.
    • (2002) Trends Biochem Sci , vol.27 , pp. 19-26
    • Bodmer, J.L.1    Schneider, P.2    Tschopp, J.3
  • 2
    • 84877757564 scopus 로고    scopus 로고
    • Molecular basis of NF-κB signaling
    • doi:10.1146/annurev-biophys-083012-130338
    • Napetschnig J, Wu H. Molecular basis of NF-κB signaling. Annu Rev Biophys (2013) 42:443-68. doi:10.1146/annurev-biophys-083012-130338.
    • (2013) Annu Rev Biophys , vol.42 , pp. 443-468
    • Napetschnig, J.1    Wu, H.2
  • 3
    • 0031465594 scopus 로고    scopus 로고
    • TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis
    • doi:10.1074/jbc.272.51.32401
    • Chicheportiche Y, Bourdon PR, Xu H, Hsu YM, Scott H, Hession C, et al. TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis. J Biol Chem (1997) 272:32401-10. doi:10.1074/jbc.272.51.32401.
    • (1997) J Biol Chem , vol.272 , pp. 32401-32410
    • Chicheportiche, Y.1    Bourdon, P.R.2    Xu, H.3    Hsu, Y.M.4    Scott, H.5    Hession, C.6
  • 4
    • 18244380611 scopus 로고    scopus 로고
    • A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis
    • doi:10.1016/S1074-7613(01)00232-1
    • Wiley SR, Cassiano L, Lofton T, Davis-Smith T, Winkles JA, Lindner V, et al. A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis. Immunity (2001) 15:837-46. doi:10.1016/S1074-7613(01)00232-1.
    • (2001) Immunity , vol.15 , pp. 837-846
    • Wiley, S.R.1    Cassiano, L.2    Lofton, T.3    Davis-Smith, T.4    Winkles, J.A.5    Lindner, V.6
  • 5
    • 0033843466 scopus 로고    scopus 로고
    • The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas
    • doi:10.1016/S0002-9440(10)64996-6
    • Feng SL, Guo Y, Factor VM, Thorgeirsson SS, Bell DW, Testa JR, et al. The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas. Am J Pathol (2000) 156:1253-61. doi:10.1016/S0002-9440(10)64996-6.
    • (2000) Am J Pathol , vol.156 , pp. 1253-1261
    • Feng, S.L.1    Guo, Y.2    Factor, V.M.3    Thorgeirsson, S.S.4    Bell, D.W.5    Testa, J.R.6
  • 6
    • 33746093941 scopus 로고    scopus 로고
    • TWEAK binding to the Fn14 cysteine-rich domain depends on charged residues located in both the A1 and D2 modules
    • doi:10.1042/BJ20051362
    • Brown SA, Hanscom HN, Vu H, Brew SA, Winkles JA. TWEAK binding to the Fn14 cysteine-rich domain depends on charged residues located in both the A1 and D2 modules. Biochem J (2006) 397:297-304. doi:10.1042/BJ20051362.
    • (2006) Biochem J , vol.397 , pp. 297-304
    • Brown, S.A.1    Hanscom, H.N.2    Vu, H.3    Brew, S.A.4    Winkles, J.A.5
  • 7
    • 0038708366 scopus 로고    scopus 로고
    • The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation
    • doi:10.1042/BJ20021730
    • Brown SA, Richards CM, Hanscom HN, Feng SL, Winkles JA. The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation. Biochem J (2003) 371:395-403. doi:10.1042/BJ20021730.
    • (2003) Biochem J , vol.371 , pp. 395-403
    • Brown, S.A.1    Richards, C.M.2    Hanscom, H.N.3    Feng, S.L.4    Winkles, J.A.5
  • 8
    • 34250211507 scopus 로고    scopus 로고
    • A previously unrecognized protein-protein interaction between TWEAK and CD163: potential biological implications
    • Bover LC, Cardó-Vila M, Kuniyasu A, Sun J, Rangel R, Takeya M, et al. A previously unrecognized protein-protein interaction between TWEAK and CD163: potential biological implications. J Immunol (2007) 178:8183-94.
    • (2007) J Immunol , vol.178 , pp. 8183-8194
    • Bover, L.C.1    Cardó-Vila, M.2    Kuniyasu, A.3    Sun, J.4    Rangel, R.5    Takeya, M.6
  • 9
    • 70350444860 scopus 로고    scopus 로고
    • The CD163-expressing macrophages recognize and internalize TWEAK: potential consequences in atherosclerosis
    • doi:10.1016/j.atherosclerosis.2009.04.033
    • Moreno JA, Muñoz-García B, Martín-Ventura JL, Madrigal-Matute J, Orbe J, Páramo JA, et al. The CD163-expressing macrophages recognize and internalize TWEAK: potential consequences in atherosclerosis. Atherosclerosis (2009) 207:103-10. doi:10.1016/j.atherosclerosis.2009.04.033.
    • (2009) Atherosclerosis , vol.207 , pp. 103-110
    • Moreno, J.A.1    Muñoz-García, B.2    Martín-Ventura, J.L.3    Madrigal-Matute, J.4    Orbe, J.5    Páramo, J.A.6
  • 11
    • 84855283949 scopus 로고    scopus 로고
    • Studies of binding of tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) to fibroblast growth factor 14 (Fn14)
    • doi:10.1074/jbc.M111.287656
    • Fick A, Lang I, Schäfer V, Seher A, Trebing J, Weisenberger D, et al. Studies of binding of tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) to fibroblast growth factor 14 (Fn14). J Biol Chem (2012) 287:484-95. doi:10.1074/jbc.M111.287656.
    • (2012) J Biol Chem , vol.287 , pp. 484-495
    • Fick, A.1    Lang, I.2    Schäfer, V.3    Seher, A.4    Trebing, J.5    Weisenberger, D.6
  • 12
    • 0041355229 scopus 로고    scopus 로고
    • TWEAK mediates signal transduction and differentiation of RAW264.7 cells in the absence of Fn14/TweakR. Evidence for a second TWEAK receptor
    • doi:10.1074/jbc.M302518200
    • Polek TC, Talpaz M, Darnay BG, Spivak-Kroizman T. TWEAK mediates signal transduction and differentiation of RAW264.7 cells in the absence of Fn14/TweakR. Evidence for a second TWEAK receptor. J Biol Chem (2003) 278:32317-23. doi:10.1074/jbc.M302518200.
    • (2003) J Biol Chem , vol.278 , pp. 32317-32323
    • Polek, T.C.1    Talpaz, M.2    Darnay, B.G.3    Spivak-Kroizman, T.4
  • 13
    • 36049022442 scopus 로고    scopus 로고
    • TWEAKing tissue remodeling by a multifunctional cytokine: role of TWEAK/Fn14 pathway in health and disease
    • doi:10.1016/j.cyto.2007.09.007
    • Burkly LC, Michaelson JS, Hahm K, Jakubowski A, Zheng TS. TWEAKing tissue remodeling by a multifunctional cytokine: role of TWEAK/Fn14 pathway in health and disease. Cytokine (2007) 40:1-16. doi:10.1016/j.cyto.2007.09.007.
    • (2007) Cytokine , vol.40 , pp. 1-16
    • Burkly, L.C.1    Michaelson, J.S.2    Hahm, K.3    Jakubowski, A.4    Zheng, T.S.5
  • 14
    • 77954227963 scopus 로고    scopus 로고
    • Tumor necrosis factor like weak inducer of apoptosis is a mitogen for liver progenitor cells
    • doi:10.1002/hep.23663
    • Tirnitz-Parker JE, Viebahn CS, Jakubowski A, Klopcic BR, Olynyk JK, Yeoh GC, et al. Tumor necrosis factor like weak inducer of apoptosis is a mitogen for liver progenitor cells. Hepatology (2010) 52:291-302. doi:10.1002/hep.23663.
    • (2010) Hepatology , vol.52 , pp. 291-302
    • Tirnitz-Parker, J.E.1    Viebahn, C.S.2    Jakubowski, A.3    Klopcic, B.R.4    Olynyk, J.K.5    Yeoh, G.C.6
  • 15
    • 77950839484 scopus 로고    scopus 로고
    • Tumour necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor Fn14 during cardiac remodelling in rats
    • doi:10.1111/j.1748-1716.2010.02080.x
    • Mustonen E, Sakkinen H, Tokola H, Isopoussu E, Aro J, Leskinen H, et al. Tumour necrosis factor-like weak inducer of apoptosis (TWEAK) and its receptor Fn14 during cardiac remodelling in rats. Acta Physiol (Oxf) (2010) 199:11-22. doi:10.1111/j.1748-1716.2010.02080.x.
    • (2010) Acta Physiol (Oxf) , vol.199 , pp. 11-22
    • Mustonen, E.1    Sakkinen, H.2    Tokola, H.3    Isopoussu, E.4    Aro, J.5    Leskinen, H.6
  • 16
    • 60449110144 scopus 로고    scopus 로고
    • TWEAK/Fn14 pathway: a nonredundant role in intestinal damage in mice through a TWEAK/intestinal epithelial cell axis
    • doi:10.1053/j.gastro.2008.11.017
    • Dohi T, Borodovsky A, Wu P, Shearstone JR, Kawashima R, Runkel L, et al. TWEAK/Fn14 pathway: a nonredundant role in intestinal damage in mice through a TWEAK/intestinal epithelial cell axis. Gastroenterology (2009) 136:912-23. doi:10.1053/j.gastro.2008.11.017.
    • (2009) Gastroenterology , vol.136 , pp. 912-923
    • Dohi, T.1    Borodovsky, A.2    Wu, P.3    Shearstone, J.R.4    Kawashima, R.5    Runkel, L.6
  • 17
    • 77949765184 scopus 로고    scopus 로고
    • The TWEAK-Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice
    • doi:10.1083/jcb.200909117
    • Mittal A, Bhatnagar S, Kumar A, Lach-Trifilieff E, Wauters S, Li H, et al. The TWEAK-Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice. J Cell Biol (2010) 188:833-49. doi:10.1083/jcb.200909117.
    • (2010) J Cell Biol , vol.188 , pp. 833-849
    • Mittal, A.1    Bhatnagar, S.2    Kumar, A.3    Lach-Trifilieff, E.4    Wauters, S.5    Li, H.6
  • 18
    • 33747173077 scopus 로고    scopus 로고
    • Fn14 is upregulated in cytokine-stimulated vascular smooth muscle cells and is expressed in human carotid atherosclerotic plaques: modulation by atorvastatin
    • doi:10.1161/01.STR.0000230648.00027.00
    • Muñoz-García B, Martín-Ventura JL, Martínez E, Sánchez S, Hernández G, Ortega L, et al. Fn14 is upregulated in cytokine-stimulated vascular smooth muscle cells and is expressed in human carotid atherosclerotic plaques: modulation by atorvastatin. Stroke (2006) 37:2044-53. doi:10.1161/01.STR.0000230648.00027.00.
    • (2006) Stroke , vol.37 , pp. 2044-2053
    • Muñoz-García, B.1    Martín-Ventura, J.L.2    Martínez, E.3    Sánchez, S.4    Hernández, G.5    Ortega, L.6
  • 19
    • 27244442108 scopus 로고    scopus 로고
    • Anti-TWEAK monoclonal antibodies reduce immune cell infiltration in the central nervous system and severity of experimental autoimmune encephalomyelitis
    • doi:10.1016/j.clim.2005.06.005
    • Desplat-Jégo S, Creidy R, Varriale S, Allaire N, Luo Y, Bernard D, et al. Anti-TWEAK monoclonal antibodies reduce immune cell infiltration in the central nervous system and severity of experimental autoimmune encephalomyelitis. Clin Immunol (2005) 117:15-23. doi:10.1016/j.clim.2005.06.005.
    • (2005) Clin Immunol , vol.117 , pp. 15-23
    • Desplat-Jégo, S.1    Creidy, R.2    Varriale, S.3    Allaire, N.4    Luo, Y.5    Bernard, D.6
  • 20
    • 33750582348 scopus 로고    scopus 로고
    • Cytokine cooperation in renal tubular cell injury: the role of TWEAK
    • doi:10.1038/sj.ki.5001866
    • Justo P, Sanz AB, Sanchez-Nino MD, Winkles JA, Lorz C, Egido J, et al. Cytokine cooperation in renal tubular cell injury: the role of TWEAK. Kidney Int (2006) 70:1750-8. doi:10.1038/sj.ki.5001866.
    • (2006) Kidney Int , vol.70 , pp. 1750-1758
    • Justo, P.1    Sanz, A.B.2    Sanchez-Nino, M.D.3    Winkles, J.A.4    Lorz, C.5    Egido, J.6
  • 21
    • 65449164651 scopus 로고    scopus 로고
    • A novel role for tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in the development of cardiac dysfunction and failure
    • doi:10.1161/CIRCULATIONAHA.108.837286
    • Jain M, Jakubowski A, Cui L, Shi J, Su L, Bauer M, et al. A novel role for tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in the development of cardiac dysfunction and failure. Circulation (2009) 119:2058-68. doi:10.1161/CIRCULATIONAHA.108.837286.
    • (2009) Circulation , vol.119 , pp. 2058-2068
    • Jain, M.1    Jakubowski, A.2    Cui, L.3    Shi, J.4    Su, L.5    Bauer, M.6
  • 22
    • 77952892382 scopus 로고    scopus 로고
    • Full-length, membrane-anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF-kappaB pathway
    • doi:10.1074/jbc.M110.131979
    • Brown SA, Ghosh A, Winkles JA. Full-length, membrane-anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF-kappaB pathway. J Biol Chem (2010) 285:17432-41. doi:10.1074/jbc.M110.131979.
    • (2010) J Biol Chem , vol.285 , pp. 17432-17441
    • Brown, S.A.1    Ghosh, A.2    Winkles, J.A.3
  • 23
    • 0037390762 scopus 로고    scopus 로고
    • TWEAK is an endothelial cell growth and chemotactic factor that also potentiates FGF-2 and VEGF-A mitogenic activity
    • doi:10.1161/01.ATV.0000062883.93715.37
    • Donohue PJ, Richards CM, Brown SA, Hanscom HN, Buschman J, Thangada S, et al. TWEAK is an endothelial cell growth and chemotactic factor that also potentiates FGF-2 and VEGF-A mitogenic activity. Arterioscler Thromb Vasc Biol (2003) 23:594-600. doi:10.1161/01.ATV.0000062883.93715.37.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 594-600
    • Donohue, P.J.1    Richards, C.M.2    Brown, S.A.3    Hanscom, H.N.4    Buschman, J.5    Thangada, S.6
  • 24
    • 28344457483 scopus 로고    scopus 로고
    • TWEAK attenuates the transition from innate to adaptive immunity
    • doi:10.1016/j.cell.2005.09.022
    • Maecker H, Varfolomeev E, Kischkel F, Lawrence D, Leblanc H, Lee W, et al. TWEAK attenuates the transition from innate to adaptive immunity. Cell (2005) 123:931-44. doi:10.1016/j.cell.2005.09.022.
    • (2005) Cell , vol.123 , pp. 931-944
    • Maecker, H.1    Varfolomeev, E.2    Kischkel, F.3    Lawrence, D.4    Leblanc, H.5    Lee, W.6
  • 25
    • 77950364992 scopus 로고    scopus 로고
    • FGF inducible 14-kDa protein (Fn14) is regulated via the RhoA/ROCK kinase pathway in cardiomyocytes and mediates nuclear factor-kappaB activation by TWEAK
    • doi:10.1007/s00395-009-0046-y
    • Chorianopoulos E, Heger T, Lutz M, Frank D, Bea F, Katus HA, et al. FGF inducible 14-kDa protein (Fn14) is regulated via the RhoA/ROCK kinase pathway in cardiomyocytes and mediates nuclear factor-kappaB activation by TWEAK. Basic Res Cardiol (2010) 105:301-13. doi:10.1007/s00395-009-0046-y.
    • (2010) Basic Res Cardiol , vol.105 , pp. 301-313
    • Chorianopoulos, E.1    Heger, T.2    Lutz, M.3    Frank, D.4    Bea, F.5    Katus, H.A.6
  • 26
    • 0034613732 scopus 로고    scopus 로고
    • Involvement of TWEAK in interferon γ-stimulated monocyte cytotoxicity
    • doi:10.1084/jem.192.9.1373
    • Nakayama M, Kayagaki N, Yamaguchi N, Okumura K, Yagita H. Involvement of TWEAK in interferon γ-stimulated monocyte cytotoxicity. J Exp Med (2000) 192:1373-80. doi:10.1084/jem.192.9.1373.
    • (2000) J Exp Med , vol.192 , pp. 1373-1380
    • Nakayama, M.1    Kayagaki, N.2    Yamaguchi, N.3    Okumura, K.4    Yagita, H.5
  • 27
    • 0141815764 scopus 로고    scopus 로고
    • TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation
    • doi:10.1074/jbc.M304266200
    • Saitoh T, Nakayama M, Nakano H, Yagita H, Yamamoto N, Yamaoka S. TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation. J Biol Chem (2003) 278:36005-12. doi:10.1074/jbc.M304266200.
    • (2003) J Biol Chem , vol.278 , pp. 36005-36012
    • Saitoh, T.1    Nakayama, M.2    Nakano, H.3    Yagita, H.4    Yamamoto, N.5    Yamaoka, S.6
  • 28
    • 73849087983 scopus 로고    scopus 로고
    • Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) enhances vascular and renal damage induced by hyperlipidemic diet in ApoE-knockout mice
    • doi:10.1161/ATVBAHA.109.194852
    • Muñoz-García B, Moreno JA, López-Franco O, Sanz AB, Martín-Ventura JL, Blanco J, et al. Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) enhances vascular and renal damage induced by hyperlipidemic diet in ApoE-knockout mice. Arterioscler Thromb Vasc Biol (2009) 29:2061-8. doi:10.1161/ATVBAHA.109.194852.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 2061-2068
    • Muñoz-García, B.1    Moreno, J.A.2    López-Franco, O.3    Sanz, A.B.4    Martín-Ventura, J.L.5    Blanco, J.6
  • 29
    • 84874353635 scopus 로고    scopus 로고
    • HMGB1 expression and secretion are increased via TWEAK-Fn14 interaction in atherosclerotic plaques and cultured monocytes
    • doi:10.1161/ATVBAHA.112.300874
    • Moreno JA, Sastre C, Madrigal-Matute J, Muñoz-García B, Ortega L, Burkly LC, et al. HMGB1 expression and secretion are increased via TWEAK-Fn14 interaction in atherosclerotic plaques and cultured monocytes. Arterioscler Thromb Vasc Biol (2013) 33:612-20. doi:10.1161/ATVBAHA.112.300874.
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 612-620
    • Moreno, J.A.1    Sastre, C.2    Madrigal-Matute, J.3    Muñoz-García, B.4    Ortega, L.5    Burkly, L.C.6
  • 30
    • 77749282951 scopus 로고    scopus 로고
    • TWEAK activates the non-canonical NFkappaB pathway in murine renal tubular cells: modulation of CCL21
    • doi:10.1371/journal.pone.0008955
    • Sanz AB, Sanchez-Niño MD, Izquierdo MC, Jakubowski A, Justo P, Blanco-Colio LM, et al. TWEAK activates the non-canonical NFkappaB pathway in murine renal tubular cells: modulation of CCL21. PLoS One (2010) 5:e8955. doi:10.1371/journal.pone.0008955.
    • (2010) PLoS One , vol.5
    • Sanz, A.B.1    Sanchez-Niño, M.D.2    Izquierdo, M.C.3    Jakubowski, A.4    Justo, P.5    Blanco-Colio, L.M.6
  • 31
    • 33847061264 scopus 로고    scopus 로고
    • Enhanced expression of the homeostatic chemokines CCL19 and CCL21 in clinical and experimental atherosclerosis: possible pathogenic role in plaque destabilization
    • doi:10.1161/01.ATV.0000255581.38523.7c
    • Damås JK, Smith C, Øie E, Fevang B, Halvorsen B, Waehre T, et al. Enhanced expression of the homeostatic chemokines CCL19 and CCL21 in clinical and experimental atherosclerosis: possible pathogenic role in plaque destabilization. Arterioscler Thromb Vasc Biol (2007) 27:614-20. doi:10.1161/01.ATV.0000255581.38523.7c.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 614-620
    • Damås, J.K.1    Smith, C.2    Øie, E.3    Fevang, B.4    Halvorsen, B.5    Waehre, T.6
  • 32
    • 80054865852 scopus 로고    scopus 로고
    • TWEAK/Fn14 pathway: an immunological switch for shaping tissue responses
    • doi:10.1111/j.1600-065X.2011.01054.x
    • Burkly LC, Michaelson JS, Zheng TS. TWEAK/Fn14 pathway: an immunological switch for shaping tissue responses. Immunol Rev (2011) 244:99-114. doi:10.1111/j.1600-065X.2011.01054.x.
    • (2011) Immunol Rev , vol.244 , pp. 99-114
    • Burkly, L.C.1    Michaelson, J.S.2    Zheng, T.S.3
  • 33
    • 33750870608 scopus 로고    scopus 로고
    • Proinflammatory effects of tumour necrosis factor-like weak inducer of apoptosis (TWEAK) on human gingival fibroblasts
    • doi:10.1111/j.1365-2249.2006.03233.x
    • Hosokawa Y, Hosokawa I, Ozaki K, Nakae H, Matsuo T. Proinflammatory effects of tumour necrosis factor-like weak inducer of apoptosis (TWEAK) on human gingival fibroblasts. Clin Exp Immunol (2006) 146:540-9. doi:10.1111/j.1365-2249.2006.03233.x.
    • (2006) Clin Exp Immunol , vol.146 , pp. 540-549
    • Hosokawa, Y.1    Hosokawa, I.2    Ozaki, K.3    Nakae, H.4    Matsuo, T.5
  • 34
    • 63249086636 scopus 로고    scopus 로고
    • Tumor necrosis factor-related weak inducer of apoptosis augments matrix metalloproteinase 9 (MMP-9) production in skeletal muscle through the activation of nuclear factor-kappaB-inducing kinase and p38 mitogen-activated protein kinase: a potential role of MMP-9 in myopathy
    • doi:10.1074/jbc.M805546200
    • Li H, Mittal A, Paul PK, Kumar M, Srivastava DS, Tyagi SC, et al. Tumor necrosis factor-related weak inducer of apoptosis augments matrix metalloproteinase 9 (MMP-9) production in skeletal muscle through the activation of nuclear factor-kappaB-inducing kinase and p38 mitogen-activated protein kinase: a potential role of MMP-9 in myopathy. J Biol Chem (2009) 284:4439-50. doi:10.1074/jbc.M805546200.
    • (2009) J Biol Chem , vol.284 , pp. 4439-4450
    • Li, H.1    Mittal, A.2    Paul, P.K.3    Kumar, M.4    Srivastava, D.S.5    Tyagi, S.C.6
  • 35
    • 36849092777 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha augments matrix metalloproteinase-9 production in skeletal muscle cells through the activation of transforming growth factor-beta-activated kinase 1 (TAK1)-dependent signaling pathway
    • doi:10.1074/jbc.M705329200
    • Srivastava AK, Qin X, Wedhas N, Arnush M, Linkhart TA, Chadwick RB, et al. Tumor necrosis factor-alpha augments matrix metalloproteinase-9 production in skeletal muscle cells through the activation of transforming growth factor-beta-activated kinase 1 (TAK1)-dependent signaling pathway. J Biol Chem (2007) 282:35113-24. doi:10.1074/jbc.M705329200.
    • (2007) J Biol Chem , vol.282 , pp. 35113-35124
    • Srivastava, A.K.1    Qin, X.2    Wedhas, N.3    Arnush, M.4    Linkhart, T.A.5    Chadwick, R.B.6
  • 36
    • 61449148439 scopus 로고    scopus 로고
    • TNF-like weak inducer of apoptosis (TWEAK) activates proinflammatory signaling pathways and gene expression through the activation of TGF-beta-activated kinase 1
    • doi:10.4049/jimmunol.0803357
    • Kumar M, Makonchuk DY, Li H, Mittal A, Kumar A. TNF-like weak inducer of apoptosis (TWEAK) activates proinflammatory signaling pathways and gene expression through the activation of TGF-beta-activated kinase 1. J Immunol (2009) 182:2439-48. doi:10.4049/jimmunol.0803357.
    • (2009) J Immunol , vol.182 , pp. 2439-2448
    • Kumar, M.1    Makonchuk, D.Y.2    Li, H.3    Mittal, A.4    Kumar, A.5
  • 37
    • 34447519304 scopus 로고    scopus 로고
    • Fibroblast growth factor inducible 14 (Fn14) is required for the expression of myogenic regulatory factors and differentiation of myoblasts into myotubes. Evidence for TWEAK-independent functions of Fn14 during myogenesis
    • doi:10.1074/jbc.M608668200
    • Dogra C, Hall SL, Wedhas N, Linkhart TA, Kumar A. Fibroblast growth factor inducible 14 (Fn14) is required for the expression of myogenic regulatory factors and differentiation of myoblasts into myotubes. Evidence for TWEAK-independent functions of Fn14 during myogenesis. J Biol Chem (2007) 282:15000-10. doi:10.1074/jbc.M608668200.
    • (2007) J Biol Chem , vol.282 , pp. 15000-15010
    • Dogra, C.1    Hall, S.L.2    Wedhas, N.3    Linkhart, T.A.4    Kumar, A.5
  • 39
    • 0344958751 scopus 로고    scopus 로고
    • TWEAK induces angiogenesis and proliferation of endothelial cells
    • doi:10.1074/jbc.274.13.8455
    • Lynch CN, Wang YC, Lund JK, Chen YW, Leal JA, Wiley SR. TWEAK induces angiogenesis and proliferation of endothelial cells. J Biol Chem (1999) 274:8455-9. doi:10.1074/jbc.274.13.8455.
    • (1999) J Biol Chem , vol.274 , pp. 8455-8459
    • Lynch, C.N.1    Wang, Y.C.2    Lund, J.K.3    Chen, Y.W.4    Leal, J.A.5    Wiley, S.R.6
  • 40
    • 0032752353 scopus 로고    scopus 로고
    • The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration
    • doi:10.1074/jbc.274.46.33166
    • Meighan-Mantha RL, Hsu DK, Guo Y, Brown SA, Feng SL, Peifley KA, et al. The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration. J Biol Chem (1999) 274:33166-76. doi:10.1074/jbc.274.46.33166.
    • (1999) J Biol Chem , vol.274 , pp. 33166-33176
    • Meighan-Mantha, R.L.1    Hsu, D.K.2    Guo, Y.3    Brown, S.A.4    Feng, S.L.5    Peifley, K.A.6
  • 41
    • 42949160019 scopus 로고    scopus 로고
    • The TWEAK-Fn14 cytokine-receptor axis: discovery, biology and therapeutic targeting
    • doi:10.1038/nrd2488
    • Winkles JA. The TWEAK-Fn14 cytokine-receptor axis: discovery, biology and therapeutic targeting. Nat Rev Drug Discov (2008) 7:411-25. doi:10.1038/nrd2488.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 411-425
    • Winkles, J.A.1
  • 42
    • 0035936802 scopus 로고    scopus 로고
    • Atherosclerosis: the road ahead
    • doi:10.1016/S0092-8674(01)00238-0
    • Glass CK, Witzum JL. Atherosclerosis: the road ahead. Cell (2001) 104:503-16. doi:10.1016/S0092-8674(01)00238-0.
    • (2001) Cell , vol.104 , pp. 503-516
    • Glass, C.K.1    Witzum, J.L.2
  • 44
    • 79151483765 scopus 로고    scopus 로고
    • Soluble TWEAK plasma levels predict expansion of human abdominal aortic aneurysms
    • doi:10.1016/j.atherosclerosis.2010.11.009
    • Martín-Ventura JL, Lindholt JS, Moreno JA, Vega de Céniga M, Meilhac O, Michel JB, et al. Soluble TWEAK plasma levels predict expansion of human abdominal aortic aneurysms. Atherosclerosis (2011) 214:486-9. doi:10.1016/j.atherosclerosis.2010.11.009.
    • (2011) Atherosclerosis , vol.214 , pp. 486-489
    • Martín-Ventura, J.L.1    Lindholt, J.S.2    Moreno, J.A.3    Vega de Céniga, M.4    Meilhac, O.5    Michel, J.B.6
  • 45
    • 0036435970 scopus 로고    scopus 로고
    • Pro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells
    • doi:10.1016/S0006-291X(02)02670-0
    • Harada N, Nakayama M, Nakano H, Fukuchi Y, Yagita H, Okumura K. Pro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells. Biochem Biophys Res Commun (2002) 299:488-93. doi:10.1016/S0006-291X(02)02670-0.
    • (2002) Biochem Biophys Res Commun , vol.299 , pp. 488-493
    • Harada, N.1    Nakayama, M.2    Nakano, H.3    Fukuchi, Y.4    Yagita, H.5    Okumura, K.6
  • 46
    • 0038242506 scopus 로고    scopus 로고
    • TNF-related weak inducer of apoptosis receptor, a TNF receptor superfamily member, activates NF-kappa B through TNF receptor-associated factors
    • doi:10.1016/S0006-291X(03)00852-0
    • Han S, Yoon K, Lee K, Kim K, Jang H, Lee NK, et al. TNF-related weak inducer of apoptosis receptor, a TNF receptor superfamily member, activates NF-kappa B through TNF receptor-associated factors. Biochem Biophys Res Commun (2003) 305:789-96. doi:10.1016/S0006-291X(03)00852-0.
    • (2003) Biochem Biophys Res Commun , vol.305 , pp. 789-796
    • Han, S.1    Yoon, K.2    Lee, K.3    Kim, K.4    Jang, H.5    Lee, N.K.6
  • 47
    • 79960426739 scopus 로고    scopus 로고
    • The nuclear factor-kappa B pathway in atherosclerosis: a potential therapeutic target for atherothrombotic vascular disease
    • doi:10.1016/j.thromres.2011.03.025
    • Pamukcu B, Lip GYH, Shantsila E. The nuclear factor-kappa B pathway in atherosclerosis: a potential therapeutic target for atherothrombotic vascular disease. Thromb Res (2011) 128:117-23. doi:10.1016/j.thromres.2011.03.025.
    • (2011) Thromb Res , vol.128 , pp. 117-123
    • Pamukcu, B.1    Lip, G.Y.H.2    Shantsila, E.3
  • 48
    • 13344261982 scopus 로고    scopus 로고
    • Activated transcription factor nuclear factor kappa B is present in the atherosclerotic lesion
    • doi:10.1172/JCI118598
    • Brand K, Page S, Rogler G, Bartsch A, Brandl R, Knuechel R, et al. Activated transcription factor nuclear factor kappa B is present in the atherosclerotic lesion. J Clin Invest (1996) 97:1715-22. doi:10.1172/JCI118598.
    • (1996) J Clin Invest , vol.97 , pp. 1715-1722
    • Brand, K.1    Page, S.2    Rogler, G.3    Bartsch, A.4    Brandl, R.5    Knuechel, R.6
  • 49
    • 0030916179 scopus 로고    scopus 로고
    • The nuclear factor kappa-B signaling pathway participates in dysregulation of vascular smooth muscle cells in vitro and in human atherosclerosis
    • doi:10.1074/jbc.272.25.15817
    • Bourcier T, Sukhova G, Libby P. The nuclear factor kappa-B signaling pathway participates in dysregulation of vascular smooth muscle cells in vitro and in human atherosclerosis. J Biol Chem (1997) 272:15817-24. doi:10.1074/jbc.272.25.15817.
    • (1997) J Biol Chem , vol.272 , pp. 15817-15824
    • Bourcier, T.1    Sukhova, G.2    Libby, P.3
  • 50
    • 0842267585 scopus 로고    scopus 로고
    • NF-kappaB activation and Fas ligand overexpression in blood and plaques of patients with carotid atherosclerosis: potential implication in plaque instability
    • doi:10.1161/01.STR.0000114876.51656.7A
    • Martin-Ventura JL, Blanco-Colio LM, Munoz-Garcia B, Gomez-Hernandez A, Arribas A, Ortega L, et al. NF-kappaB activation and Fas ligand overexpression in blood and plaques of patients with carotid atherosclerosis: potential implication in plaque instability. Stroke (2004) 35:458-63. doi:10.1161/01.STR.0000114876.51656.7A.
    • (2004) Stroke , vol.35 , pp. 458-463
    • Martin-Ventura, J.L.1    Blanco-Colio, L.M.2    Munoz-Garcia, B.3    Gomez-Hernandez, A.4    Arribas, A.5    Ortega, L.6
  • 51
    • 33744542153 scopus 로고    scopus 로고
    • Tumor necrosis factor-like inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor kappa B and degradation of MyoD protein
    • doi:10.1074/jbc.M511131200
    • Droga C, Changotra H, Mohan S, Kumar A. Tumor necrosis factor-like inducer of apoptosis inhibits skeletal myogenesis through sustained activation of nuclear factor kappa B and degradation of MyoD protein. J Biol Chem (2006) 281:10327-33. doi:10.1074/jbc.M511131200.
    • (2006) J Biol Chem , vol.281 , pp. 10327-10333
    • Droga, C.1    Changotra, H.2    Mohan, S.3    Kumar, A.4
  • 52
    • 10844249434 scopus 로고    scopus 로고
    • Soluble tumor necrosis factor-like weak inducer of apoptosis overexpression in HEK293 cells promotes tumor growth and angiogenesis in athymic nude mice
    • doi:10.1158/0008-5472.CAN-04-1879
    • Ho DH, Vu H, Brown SA, Donohue PJ, Hanscom HN, Winkles JA. Soluble tumor necrosis factor-like weak inducer of apoptosis overexpression in HEK293 cells promotes tumor growth and angiogenesis in athymic nude mice. Cancer Res (2004) 64:8968-72. doi:10.1158/0008-5472.CAN-04-1879.
    • (2004) Cancer Res , vol.64 , pp. 8968-8972
    • Ho, D.H.1    Vu, H.2    Brown, S.A.3    Donohue, P.J.4    Hanscom, H.N.5    Winkles, J.A.6
  • 53
  • 55
    • 73849096180 scopus 로고    scopus 로고
    • Fn14-Fc fusion protein regulates atherosclerosis in ApoE-/- mice and inhibits macrophage lipid uptake in vitro
    • doi:10.1161/ATVBAHA.109.195040
    • Schapira K, Burkly LC, Zheng TS, Wu P, Groeneweg M, Rousch M, et al. Fn14-Fc fusion protein regulates atherosclerosis in ApoE-/- mice and inhibits macrophage lipid uptake in vitro. Arterioscler Thromb Vasc Biol (2009) 29:2021-7. doi:10.1161/ATVBAHA.109.195040.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 2021-2027
    • Schapira, K.1    Burkly, L.C.2    Zheng, T.S.3    Wu, P.4    Groeneweg, M.5    Rousch, M.6
  • 56
    • 79955907143 scopus 로고    scopus 로고
    • The role of matrix metalloproteinases in atherothrombosis
    • doi:10.1007/s11883-010-0159-7
    • Ketelhuth DF, Bäck M. The role of matrix metalloproteinases in atherothrombosis. Curr Atheroscler Rep (2011) 13:162-9. doi:10.1007/s11883-010-0159-7.
    • (2011) Curr Atheroscler Rep , vol.13 , pp. 162-169
    • Ketelhuth, D.F.1    Bäck, M.2
  • 57
    • 0035131637 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor superfamily 12 may destabilize atherosclerotic plaques by inducing matrix metalloproteinases
    • doi:10.1253/jcj.65.136
    • Kim SH, Lee WH, Kwon BS, Oh GT, Choi YH, Park JE. Tumor necrosis factor receptor superfamily 12 may destabilize atherosclerotic plaques by inducing matrix metalloproteinases. Circ J (2001) 65:136-8. doi:10.1253/jcj.65.136.
    • (2001) Circ J , vol.65 , pp. 136-138
    • Kim, S.H.1    Lee, W.H.2    Kwon, B.S.3    Oh, G.T.4    Choi, Y.H.5    Park, J.E.6
  • 58
    • 33645288318 scopus 로고    scopus 로고
    • Role of tissue factor in hemostasis and thrombosis
    • doi:10.1016/j.bmcd.2005.12.008
    • Mackman N. Role of tissue factor in hemostasis and thrombosis. Blood Cells Mol Dis (2006) 36:104-7. doi:10.1016/j.bmcd.2005.12.008.
    • (2006) Blood Cells Mol Dis , vol.36 , pp. 104-107
    • Mackman, N.1
  • 59
    • 13844306360 scopus 로고    scopus 로고
    • Pivotal role of plasminogen-activator inhibitor 1 in vascular disease
    • doi:10.1111/j.1742-1241.2005.00379.x
    • Agirbasli M. Pivotal role of plasminogen-activator inhibitor 1 in vascular disease. Int J Clin Pract (2005) 59:102-6. doi:10.1111/j.1742-1241.2005.00379.x.
    • (2005) Int J Clin Pract , vol.59 , pp. 102-106
    • Agirbasli, M.1
  • 60
    • 78650467139 scopus 로고    scopus 로고
    • TWEAK-Fn14 interaction enhances plasminogen activator inhibitor 1 and tissue factor expression in atherosclerotic plaques and in cultured vascular smooth muscle cells
    • doi:10.1093/cvr/cvq278
    • Muñoz-García B, Madrigal-Matute J, Moreno JA, Martin-Ventura JL, López-Franco O, Sastre C, et al. TWEAK-Fn14 interaction enhances plasminogen activator inhibitor 1 and tissue factor expression in atherosclerotic plaques and in cultured vascular smooth muscle cells. Cardiovasc Res (2011) 89:225-33. doi:10.1093/cvr/cvq278.
    • (2011) Cardiovasc Res , vol.89 , pp. 225-233
    • Muñoz-García, B.1    Madrigal-Matute, J.2    Moreno, J.A.3    Martin-Ventura, J.L.4    López-Franco, O.5    Sastre, C.6
  • 61
    • 60449094498 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • doi:10.1161/CIRCULATIONAHA.108.191259
    • Lloyd-Jones D, Adams R, Carnethon M, De SG, Ferguson TB, Flegal K, et al. Heart disease and stroke statistics-2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation (2009) 119:480-6. doi:10.1161/CIRCULATIONAHA.108.191259.
    • (2009) Circulation , vol.119 , pp. 480-486
    • Lloyd-Jones, D.1    Adams, R.2    Carnethon, M.3    De, S.G.4    Ferguson, T.B.5    Flegal, K.6
  • 62
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: an integrated view
    • doi:10.1016/S0166-2236(99)01401-0
    • Dirnagl U, Iadecola C, Moskowitz MA. Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci (1999) 22:391-7. doi:10.1016/S0166-2236(99)01401-0.
    • (1999) Trends Neurosci , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 63
    • 55649111573 scopus 로고    scopus 로고
    • Induction of the cytokine TWEAK and its receptor Fn14 in ischemic stroke
    • doi:10.1016/j.jns.2008.08.005
    • Inta I, Frauenknecht K, Dörr H, Kohlhof P, Rabsilber T, Auffarth GU, et al. Induction of the cytokine TWEAK and its receptor Fn14 in ischemic stroke. J Neurol Sci (2008) 275:117-20. doi:10.1016/j.jns.2008.08.005.
    • (2008) J Neurol Sci , vol.275 , pp. 117-120
    • Inta, I.1    Frauenknecht, K.2    Dörr, H.3    Kohlhof, P.4    Rabsilber, T.5    Auffarth, G.U.6
  • 64
    • 4644228323 scopus 로고    scopus 로고
    • Tumor necrosis factor-like weak inducer of apoptosis-induced neurodegeneration
    • doi:10.1523/JNEUROSCI.1089-04.2004
    • Potrovita I, Zhang W, Burkly L, Hahm K, Lincecum J, Wang MZ, et al. Tumor necrosis factor-like weak inducer of apoptosis-induced neurodegeneration. J Neurosci (2004) 24:8237-44. doi:10.1523/JNEUROSCI.1089-04.2004.
    • (2004) J Neurosci , vol.24 , pp. 8237-8244
    • Potrovita, I.1    Zhang, W.2    Burkly, L.3    Hahm, K.4    Lincecum, J.5    Wang, M.Z.6
  • 65
    • 13244257271 scopus 로고    scopus 로고
    • A soluble Fn14-Fc decoy receptor reduces infarct volume in a murine model of cerebral ischemia
    • doi:10.1016/S0002-9440(10)62273-0
    • Yepes M, Brown SA, Moore EG, Smith EP, Lawrence DA, Winkles JA. A soluble Fn14-Fc decoy receptor reduces infarct volume in a murine model of cerebral ischemia. Am J Pathol (2005) 166:511-20. doi:10.1016/S0002-9440(10)62273-0.
    • (2005) Am J Pathol , vol.166 , pp. 511-520
    • Yepes, M.1    Brown, S.A.2    Moore, E.G.3    Smith, E.P.4    Lawrence, D.A.5    Winkles, J.A.6
  • 66
    • 33847209525 scopus 로고    scopus 로고
    • TWEAK-Fn14 pathway inhibition protects the integrity of the neurovascular unit during cerebral ischemia
    • doi:10.1038/sj.jcbfm.9600368
    • Zhang X, Winkles JA, Gongora MC, Polavarapu R, Michaelson JS, Hahm K, et al. TWEAK-Fn14 pathway inhibition protects the integrity of the neurovascular unit during cerebral ischemia. J Cereb Blood Flow Metab (2007) 27:534-44. doi:10.1038/sj.jcbfm.9600368.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 534-544
    • Zhang, X.1    Winkles, J.A.2    Gongora, M.C.3    Polavarapu, R.4    Michaelson, J.S.5    Hahm, K.6
  • 67
    • 78650175484 scopus 로고    scopus 로고
    • Tumor necrosis factor-like weak inducer of apoptosis and fibroblast growth factor-inducible 14 mediate cerebral ischemia-induced poly (ADP-ribose) polymerase-1 activation and neuronal death
    • doi:10.1016/j.neuroscience.2010.10.029
    • Haile WB, Echeverry R, Wu F, Guzman J, An J, Wu J, et al. Tumor necrosis factor-like weak inducer of apoptosis and fibroblast growth factor-inducible 14 mediate cerebral ischemia-induced poly (ADP-ribose) polymerase-1 activation and neuronal death. Neuroscience (2010) 171:1256-64. doi:10.1016/j.neuroscience.2010.10.029.
    • (2010) Neuroscience , vol.171 , pp. 1256-1264
    • Haile, W.B.1    Echeverry, R.2    Wu, F.3    Guzman, J.4    An, J.5    Wu, J.6
  • 68
    • 0043071539 scopus 로고    scopus 로고
    • Cerebral microvessel responses to focal ischemia
    • doi:10.1097/01.WCB.0000078322.96027.78
    • del Zoppo GJ, Mabuchi T. Cerebral microvessel responses to focal ischemia. J Cereb Blood Flow Metab (2003) 23:879-94. doi:10.1097/01.WCB.0000078322.96027.78.
    • (2003) J Cereb Blood Flow Metab , vol.23 , pp. 879-894
    • del Zoppo, G.J.1    Mabuchi, T.2
  • 69
    • 0038041055 scopus 로고    scopus 로고
    • Building up the blood-brain barrier
    • doi:10.1038/nm0703-828
    • Rieckmann P, Engelhardt B. Building up the blood-brain barrier. Nat Med (2003) 9:828-9. doi:10.1038/nm0703-828.
    • (2003) Nat Med , vol.9 , pp. 828-829
    • Rieckmann, P.1    Engelhardt, B.2
  • 70
    • 27744432820 scopus 로고    scopus 로고
    • Tumor necrosis factor-like weak inducer of apoptosis increases the permeability of the neurovascular unit through nuclear factor-kappa B pathway activation
    • Polavarapu R, Gongora MC, Winkles JA, Yepes M. Tumor necrosis factor-like weak inducer of apoptosis increases the permeability of the neurovascular unit through nuclear factor-kappa B pathway activation. J Neurosci (2005) 25:10094-100.
    • (2005) J Neurosci , vol.25 , pp. 10094-10100
    • Polavarapu, R.1    Gongora, M.C.2    Winkles, J.A.3    Yepes, M.4
  • 71
    • 34247132376 scopus 로고    scopus 로고
    • Identification of soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK) as a possible biomarker of subclinical atherosclerosis
    • doi:10.1161/01.ATV.0000258972.10109.ff
    • Blanco-Colio LM, Martín-Ventura JL, Muñóz-García B, Orbe J, Páramo JA, Michel JB, et al. Identification of soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK) as a possible biomarker of subclinical atherosclerosis. Arterioscler Thromb Vasc Biol (2007) 27:916-22. doi:10.1161/01.ATV.0000258972.10109.ff.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 916-922
    • Blanco-Colio, L.M.1    Martín-Ventura, J.L.2    Muñóz-García, B.3    Orbe, J.4    Páramo, J.A.5    Michel, J.B.6
  • 72
    • 47649121369 scopus 로고    scopus 로고
    • Serum levels of the atherosclerosis biomarker sTWEAK are decreased in type 2 diabetes and end-stage renal disease
    • doi:10.1016/j.atherosclerosis.2007.10.022
    • Kralisch S, Ziegelmeier M, Bachmann A, Seeger J, Lössner U, Blüher M, et al. Serum levels of the atherosclerosis biomarker sTWEAK are decreased in type 2 diabetes and end-stage renal disease. Atherosclerosis (2008) 199:440-4. doi:10.1016/j.atherosclerosis.2007.10.022.
    • (2008) Atherosclerosis , vol.199 , pp. 440-444
    • Kralisch, S.1    Ziegelmeier, M.2    Bachmann, A.3    Seeger, J.4    Lössner, U.5    Blüher, M.6
  • 74
    • 73449115326 scopus 로고    scopus 로고
    • Soluble TWEAK plasma levels as a novel biomarker of endothelial function in patients with chronic kidney disease
    • doi:10.2215/CJN.02760409
    • Yilmaz MI, Carrero JJ, Ortiz A, Martín-Ventura JL, Sonmez A, Saglam M, et al. Soluble TWEAK plasma levels as a novel biomarker of endothelial function in patients with chronic kidney disease. Clin J Am Soc Nephrol (2009) 4:1716-23. doi:10.2215/CJN.02760409.
    • (2009) Clin J Am Soc Nephrol , vol.4 , pp. 1716-1723
    • Yilmaz, M.I.1    Carrero, J.J.2    Ortiz, A.3    Martín-Ventura, J.L.4    Sonmez, A.5    Saglam, M.6
  • 75
    • 77954802226 scopus 로고    scopus 로고
    • Combined therapy with renin-angiotensin system and calcium channel blockers in type 2 diabetic hypertensive patients with proteinuria: effects on soluble TWEAK, PTX3, and flow-mediated dilation
    • doi:10.2215/CJN.01110210
    • Yilmaz MI, Carrero JJ, Martín-Ventura JL, Sonmez A, Saglam M, Celik T, et al. Combined therapy with renin-angiotensin system and calcium channel blockers in type 2 diabetic hypertensive patients with proteinuria: effects on soluble TWEAK, PTX3, and flow-mediated dilation. Clin J Am Soc Nephrol (2010) 5:1174-81. doi:10.2215/CJN.01110210.
    • (2010) Clin J Am Soc Nephrol , vol.5 , pp. 1174-1181
    • Yilmaz, M.I.1    Carrero, J.J.2    Martín-Ventura, J.L.3    Sonmez, A.4    Saglam, M.5    Celik, T.6
  • 76
    • 79955566226 scopus 로고    scopus 로고
    • Soluble TWEAK and PTX3 in nondialysis CKD patients: impact on endothelial dysfunction and cardiovascular outcomes
    • doi:10.2215/CJN.09231010
    • Yilmaz MI, Sonmez A, Ortiz A, Saglam M, Kilic S, Eyileten T, et al. Soluble TWEAK and PTX3 in nondialysis CKD patients: impact on endothelial dysfunction and cardiovascular outcomes. Clin J Am Soc Nephrol (2011) 6:785-92. doi:10.2215/CJN.09231010.
    • (2011) Clin J Am Soc Nephrol , vol.6 , pp. 785-792
    • Yilmaz, M.I.1    Sonmez, A.2    Ortiz, A.3    Saglam, M.4    Kilic, S.5    Eyileten, T.6
  • 78
    • 70350673929 scopus 로고    scopus 로고
    • Decreased soluble TWEAK levels predict an adverse prognosis in patients with chronic stable heart failure
    • doi:10.1093/eurjhf/hfp139
    • Chorianopoulos E, Rosenberg M, Zugck C, Wolf J, Katus HA, Frey N. Decreased soluble TWEAK levels predict an adverse prognosis in patients with chronic stable heart failure. Eur J Heart Fail (2009) 11:1050-6. doi:10.1093/eurjhf/hfp139.
    • (2009) Eur J Heart Fail , vol.11 , pp. 1050-1056
    • Chorianopoulos, E.1    Rosenberg, M.2    Zugck, C.3    Wolf, J.4    Katus, H.A.5    Frey, N.6
  • 79
    • 0141504305 scopus 로고    scopus 로고
    • The clinical implications of endothelial dysfunction
    • doi:10.1016/S0735-1097(03)00994-X
    • Widlansky ME, Gokce N, Keaney JF Jr, Vita JA. The clinical implications of endothelial dysfunction. J Am Coll Cardiol (2003) 42:1149-60. doi:10.1016/S0735-1097(03)00994-X.
    • (2003) J Am Coll Cardiol , vol.42 , pp. 1149-1160
    • Widlansky, M.E.1    Gokce, N.2    Keaney Jr., J.F.3    Vita, J.A.4
  • 80
    • 0037031310 scopus 로고    scopus 로고
    • Endothelial function: a barometer for cardiovascular risk?
    • doi:10.1161/01.CIR.0000028581.07992.56
    • Vita JA, Keaney JF Jr. Endothelial function: a barometer for cardiovascular risk? Circulation (2002) 106:640-2. doi:10.1161/01.CIR.0000028581.07992.56.
    • (2002) Circulation , vol.106 , pp. 640-642
    • Vita, J.A.1    Keaney Jr., J.F.2
  • 81
    • 0030826182 scopus 로고    scopus 로고
    • Common carotid intima-media thickness and risk of stroke and myocardial infarction: the Rotterdam study
    • doi:10.1161/01.CIR.96.5.1432
    • Bots ML, Hoes AW, Koudstaal PJ, Hofman A, Grobbee DE. Common carotid intima-media thickness and risk of stroke and myocardial infarction: the Rotterdam study. Circulation (1997) 128:262-9. doi:10.1161/01.CIR.96.5.1432.
    • (1997) Circulation , vol.128 , pp. 262-269
    • Bots, M.L.1    Hoes, A.W.2    Koudstaal, P.J.3    Hofman, A.4    Grobbee, D.E.5
  • 82
    • 84866793916 scopus 로고    scopus 로고
    • Soluble TWEAK and cardiovascular morbidity and mortality in chronic kidney disease patients
    • Hassan SB, El-demery AB, Ahmed AI, Abukhalil RE. Soluble TWEAK and cardiovascular morbidity and mortality in chronic kidney disease patients. Arab J Nephrol Transplant (2012) 5:27-32.
    • (2012) Arab J Nephrol Transplant , vol.5 , pp. 27-32
    • Hassan, S.B.1    El-demery, A.B.2    Ahmed, A.I.3    Abukhalil, R.E.4
  • 83
    • 84889642341 scopus 로고    scopus 로고
    • Soluble TWEAK is associated with atherosclerotic burden in patients with chronic kidney disease
    • doi:10.5301/jn.5000245
    • Valdivielso JM, Coll B, Martín-Ventura JL, Moreno JA, Egido J, Fernández E, et al. Soluble TWEAK is associated with atherosclerotic burden in patients with chronic kidney disease. J Nephrol (2013) 26:1105-13. doi:10.5301/jn.5000245.
    • (2013) J Nephrol , vol.26 , pp. 1105-1113
    • Valdivielso, J.M.1    Coll, B.2    Martín-Ventura, J.L.3    Moreno, J.A.4    Egido, J.5    Fernández, E.6
  • 84
    • 84880288779 scopus 로고    scopus 로고
    • Soluble TWEAK independently predicts atherosclerosis in renal transplant patients
    • doi:10.1186/1471-2369-14-144
    • Turkmen K, Tonbul HZ, Erdur FM, Toker A, Biyik Z, Ozbiner H, et al. Soluble TWEAK independently predicts atherosclerosis in renal transplant patients. BMC Nephrol (2013) 14:144. doi:10.1186/1471-2369-14-144.
    • (2013) BMC Nephrol , vol.14 , pp. 144
    • Turkmen, K.1    Tonbul, H.Z.2    Erdur, F.M.3    Toker, A.4    Biyik, Z.5    Ozbiner, H.6
  • 85
    • 84872482341 scopus 로고    scopus 로고
    • The relationships between serum sTWEAK, FGF-23 levels, and carotid atherosclerosis in renal transplant patients
    • doi:10.3109/0886022X.2012.734890
    • Gungor O, Kismali E, Sisman AR, Kircelli F, Carrero JJ, Tatar E, et al. The relationships between serum sTWEAK, FGF-23 levels, and carotid atherosclerosis in renal transplant patients. Ren Fail (2013) 35:77-81. doi:10.3109/0886022X.2012.734890.
    • (2013) Ren Fail , vol.35 , pp. 77-81
    • Gungor, O.1    Kismali, E.2    Sisman, A.R.3    Kircelli, F.4    Carrero, J.J.5    Tatar, E.6
  • 86
    • 82955167882 scopus 로고    scopus 로고
    • Impact of soluble TWEAK and CD163/TWEAK ratio on long-term cardiovascular mortality in patients with peripheral arterial disease
    • doi:10.1016/j.atherosclerosis.2011.09.016
    • Urbonaviciene G, Martin-Ventura JL, Lindholt JS, Urbonavicius S, Moreno JA, Egido J, et al. Impact of soluble TWEAK and CD163/TWEAK ratio on long-term cardiovascular mortality in patients with peripheral arterial disease. Atherosclerosis (2011) 219:892-9. doi:10.1016/j.atherosclerosis.2011.09.016.
    • (2011) Atherosclerosis , vol.219 , pp. 892-899
    • Urbonaviciene, G.1    Martin-Ventura, J.L.2    Lindholt, J.S.3    Urbonavicius, S.4    Moreno, J.A.5    Egido, J.6
  • 87
    • 84897018442 scopus 로고    scopus 로고
    • A panel of biomarkers is associated with increased risk for the presence and progression of atherosclerosis in women with systemic lupus erythematosus
    • doi:10.1002/art.38204
    • McMahon M, Skaggs BJ, Grossman J, Sahakian L, Fitzgerald J, Wong WK, et al. A panel of biomarkers is associated with increased risk for the presence and progression of atherosclerosis in women with systemic lupus erythematosus. Arthritis Rheum (2013) 66(1):130-9. doi:10.1002/art.38204.
    • (2013) Arthritis Rheum , vol.66 , Issue.1 , pp. 130-139
    • McMahon, M.1    Skaggs, B.J.2    Grossman, J.3    Sahakian, L.4    Fitzgerald, J.5    Wong, W.K.6
  • 88
    • 78649736865 scopus 로고    scopus 로고
    • Differences in the predictive value of tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in advanced ischemic and non-ischemic heart failure
    • doi:10.1016/j.atherosclerosis.2010.08.061
    • Richter B, Rychli K, Hohensinner PJ, Berger R, Mörtl D, Neuhold S, et al. Differences in the predictive value of tumor necrosis factor-like weak inducer of apoptosis (TWEAK) in advanced ischemic and non-ischemic heart failure. Atherosclerosis (2010) 213:545-8. doi:10.1016/j.atherosclerosis.2010.08.061.
    • (2010) Atherosclerosis , vol.213 , pp. 545-548
    • Richter, B.1    Rychli, K.2    Hohensinner, P.J.3    Berger, R.4    Mörtl, D.5    Neuhold, S.6
  • 89
    • 0037107399 scopus 로고    scopus 로고
    • CD40 regulates the processing of NF-[kappa]B2 p100 to p52
    • doi:10.1093/emboj/cdf542
    • Coope HJ, Atkinson PG, Huhse B, Belich M, Janzen J, Holman MJ, et al. CD40 regulates the processing of NF-[kappa]B2 p100 to p52. EMBO J (2000) 21:5375-85. doi:10.1093/emboj/cdf542.
    • (2000) EMBO J , vol.21 , pp. 5375-5385
    • Coope, H.J.1    Atkinson, P.G.2    Huhse, B.3    Belich, M.4    Janzen, J.5    Holman, M.J.6
  • 90
    • 0036794398 scopus 로고    scopus 로고
    • BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells
    • doi:10.1038/ni842
    • Claudio E, Brown K, Park S, Wang H, Siebenlist U. BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells. Nat Immunol (2002) 3:958-65. doi:10.1038/ni842.
    • (2002) Nat Immunol , vol.3 , pp. 958-965
    • Claudio, E.1    Brown, K.2    Park, S.3    Wang, H.4    Siebenlist, U.5
  • 91
    • 18644380147 scopus 로고    scopus 로고
    • The lymphotoxin-b receptor induces different patterns of gene expression via two NF-kappaB pathways
    • doi:10.1016/S1074-7613(02)00423-5
    • Dejardin E, Droin NM, Delhase M, Haas E, Cao Y, Makris C, et al. The lymphotoxin-b receptor induces different patterns of gene expression via two NF-kappaB pathways. Immunity (2002) 17:525-35. doi:10.1016/S1074-7613(02)00423-5.
    • (2002) Immunity , vol.17 , pp. 525-535
    • Dejardin, E.1    Droin, N.M.2    Delhase, M.3    Haas, E.4    Cao, Y.5    Makris, C.6
  • 92
    • 0042386014 scopus 로고    scopus 로고
    • The IkappaB function of NF-kappaB2 p100 controls stimulated osteoclastogenesis
    • doi:10.1084/jem.20030116
    • Novack DV, Yin L, Hagen-Stapleton A, Schreiber RD, Goeddel DV, Ross FP, et al. The IkappaB function of NF-kappaB2 p100 controls stimulated osteoclastogenesis. J Exp Med (2003) 198:771-81. doi:10.1084/jem.20030116.
    • (2003) J Exp Med , vol.198 , pp. 771-781
    • Novack, D.V.1    Yin, L.2    Hagen-Stapleton, A.3    Schreiber, R.D.4    Goeddel, D.V.5    Ross, F.P.6
  • 93
    • 5644302162 scopus 로고    scopus 로고
    • Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase
    • doi:10.1016/j.immuni.2004.08.009
    • Ramakrishnan P, Wang W, Wallach D. Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase. Immunity (2004) 21:477-89. doi:10.1016/j.immuni.2004.08.009.
    • (2004) Immunity , vol.21 , pp. 477-489
    • Ramakrishnan, P.1    Wang, W.2    Wallach, D.3
  • 94
    • 77149136451 scopus 로고    scopus 로고
    • Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile
    • doi:10.1084/jem.20091293
    • Lutgens E, Lievens D, Beckers L, Wijnands E, Soehnlein O, Zernecke A, et al. Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile. J Exp Med (2010) 207:391-404. doi:10.1084/jem.20091293.
    • (2010) J Exp Med , vol.207 , pp. 391-404
    • Lutgens, E.1    Lievens, D.2    Beckers, L.3    Wijnands, E.4    Soehnlein, O.5    Zernecke, A.6
  • 95
    • 34247527793 scopus 로고    scopus 로고
    • CD40 ligand mediates inflammation independently of CD40 by interaction with Mac-1
    • doi:10.1161/CIRCULATIONAHA.106.683201
    • Zirlik A, Maier C, Gerdes N, MacFarlane L, Soosairajah J, Bavendiek U, et al. CD40 ligand mediates inflammation independently of CD40 by interaction with Mac-1. Circulation (2007) 115:1571-80. doi:10.1161/CIRCULATIONAHA.106.683201.
    • (2007) Circulation , vol.115 , pp. 1571-1580
    • Zirlik, A.1    Maier, C.2    Gerdes, N.3    MacFarlane, L.4    Soosairajah, J.5    Bavendiek, U.6
  • 98
    • 2642608661 scopus 로고    scopus 로고
    • Reduction of atherosclerosis in mice by inhibition of CD40 signalling
    • doi:10.1038/28204
    • Mach F, Schonbeck U, Sukhova GK, Atkinson E, Libby P. Reduction of atherosclerosis in mice by inhibition of CD40 signalling. Nature (1998) 394:200-3. doi:10.1038/28204.
    • (1998) Nature , vol.394 , pp. 200-203
    • Mach, F.1    Schonbeck, U.2    Sukhova, G.K.3    Atkinson, E.4    Libby, P.5
  • 99
    • 0034691108 scopus 로고    scopus 로고
    • Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice
    • doi:10.1073/pnas.97.13.7458
    • Schonbeck U, Sukhova GK, Shimizu K, Match F, Libby P. Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice. Proc Natl Acad Sci U S A (2000) 97:7458-63. doi:10.1073/pnas.97.13.7458.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 7458-7463
    • Schonbeck, U.1    Sukhova, G.K.2    Shimizu, K.3    Match, F.4    Libby, P.5
  • 100
    • 20144369473 scopus 로고    scopus 로고
    • Atherogenesis in mice does not require CD40 ligand from bone marrow-derived cells
    • doi:10.1161/01.ATV.0000161420.55482.ef
    • Bavendiek U, Zirlik A, LaClair S, MacFarlane L, Libby P, Schönbeck U. Atherogenesis in mice does not require CD40 ligand from bone marrow-derived cells. Arterioscler Thromb Vasc Biol (2005) 25:1244-9. doi:10.1161/01.ATV.0000161420.55482.ef.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1244-1249
    • Bavendiek, U.1    Zirlik, A.2    LaClair, S.3    MacFarlane, L.4    Libby, P.5    Schönbeck, U.6
  • 101
    • 25444485654 scopus 로고    scopus 로고
    • Leukocyte CD40L deficiency affects the CD25(+) CD4 T cell population but does not affect atherosclerosis
    • doi:10.1016/j.atherosclerosis.2005.03.051
    • Smook ML, Heeringa P, Damoiseaux JG, Daemen MJ, de Winther MP, Gijbels MJ, et al. Leukocyte CD40L deficiency affects the CD25(+) CD4 T cell population but does not affect atherosclerosis. Atherosclerosis (2005) 183:275-82. doi:10.1016/j.atherosclerosis.2005.03.051.
    • (2005) Atherosclerosis , vol.183 , pp. 275-282
    • Smook, M.L.1    Heeringa, P.2    Damoiseaux, J.G.3    Daemen, M.J.4    de Winther, M.P.5    Gijbels, M.J.6
  • 102
    • 78549272749 scopus 로고    scopus 로고
    • Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis
    • doi:10.1182/blood-2010-01-261206
    • Lievens D, Zernecke A, Seijkens T, Soehnlein O, Beckers L, Munnix IC, et al. Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis. Blood (2010) 116:4317-27. doi:10.1182/blood-2010-01-261206.
    • (2010) Blood , vol.116 , pp. 4317-4327
    • Lievens, D.1    Zernecke, A.2    Seijkens, T.3    Soehnlein, O.4    Beckers, L.5    Munnix, I.C.6
  • 103
    • 84855369823 scopus 로고    scopus 로고
    • Depletion of B2 but not B1a B cells in BAFF receptor-deficient ApoE mice attenuates atherosclerosis by potently ameliorating arterial inflammation
    • doi:10.1371/journal.pone.0029371
    • Kyaw T, Tay C, Hosseini H, Kanellakis P, Gadowski T, MacKay F, et al. Depletion of B2 but not B1a B cells in BAFF receptor-deficient ApoE mice attenuates atherosclerosis by potently ameliorating arterial inflammation. PLoS One (2012) 7:e29371. doi:10.1371/journal.pone.0029371.
    • (2012) PLoS One , vol.7
    • Kyaw, T.1    Tay, C.2    Hosseini, H.3    Kanellakis, P.4    Gadowski, T.5    MacKay, F.6
  • 104
    • 85027931795 scopus 로고    scopus 로고
    • BAFF receptor deficiency reduces the development of atherosclerosis in mice-brief report
    • doi:10.1161/ATVBAHA.111.244731
    • Sage AP, Tsiantoulas D, Baker L, Harrison J, Masters L, Murphy D, et al. BAFF receptor deficiency reduces the development of atherosclerosis in mice-brief report. Arterioscler Thromb Vasc Biol (2012) 32:1573-6. doi:10.1161/ATVBAHA.111.244731.
    • (2012) Arterioscler Thromb Vasc Biol , vol.32 , pp. 1573-1576
    • Sage, A.P.1    Tsiantoulas, D.2    Baker, L.3    Harrison, J.4    Masters, L.5    Murphy, D.6
  • 105
    • 84875752804 scopus 로고    scopus 로고
    • BAFF receptor mAb treatment ameliorates development and progression of atherosclerosis in hyperlipidemic ApoE(-/-) mice
    • doi:10.1371/journal.pone.0060430
    • Kyaw T, Cui P, Tay C, Kanellakis P, Hosseini H, Liu E, et al. BAFF receptor mAb treatment ameliorates development and progression of atherosclerosis in hyperlipidemic ApoE(-/-) mice. PLoS One (2013) 8:e60430. doi:10.1371/journal.pone.0060430.
    • (2013) PLoS One , vol.8
    • Kyaw, T.1    Cui, P.2    Tay, C.3    Kanellakis, P.4    Hosseini, H.5    Liu, E.6
  • 106
    • 60549092550 scopus 로고    scopus 로고
    • Lymphotoxin β receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE -/- mice
    • doi:10.1084/jem.20080752
    • Gräbner R, Lötzer K, Döpping S, Hildner M, Radke D, Beer M, et al. Lymphotoxin β receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE -/- mice. J Exp Med (2009) 206:233-48. doi:10.1084/jem.20080752.
    • (2009) J Exp Med , vol.206 , pp. 233-248
    • Gräbner, R.1    Lötzer, K.2    Döpping, S.3    Hildner, M.4    Radke, D.5    Beer, M.6
  • 107
    • 33747423277 scopus 로고    scopus 로고
    • Osteoprotegerin inactivation accelerates advanced atherosclerotic lesion progression and calcification in older ApoE-/-mice
    • doi:10.1161/01.ATV.0000236428.91125.e6
    • Bennett BJ, Scatena M, Kirk EA, Rattazzi M, Varon RM, Averill M, et al. Osteoprotegerin inactivation accelerates advanced atherosclerotic lesion progression and calcification in older ApoE-/-mice. Arterioscler Thromb Vasc Biol (2006) 26:2117-24. doi:10.1161/01.ATV.0000236428.91125.e6.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 2117-2124
    • Bennett, B.J.1    Scatena, M.2    Kirk, E.A.3    Rattazzi, M.4    Varon, R.M.5    Averill, M.6
  • 108
    • 38349133382 scopus 로고    scopus 로고
    • Osteoprotegerin inhibits vascular calcification without affecting atherosclerosis in LDLR(-/-) mice
    • doi:10.1161/CIRCULATIONAHA.107.707380
    • Morony S, Tintut Y, Zhang Z, Cattley RC, Van G, Dwyer D, et al. Osteoprotegerin inhibits vascular calcification without affecting atherosclerosis in LDLR(-/-) mice. Circulation (2008) 117:411-20. doi:10.1161/CIRCULATIONAHA.107.707380.
    • (2008) Circulation , vol.117 , pp. 411-420
    • Morony, S.1    Tintut, Y.2    Zhang, Z.3    Cattley, R.C.4    Van, G.5    Dwyer, D.6
  • 110
    • 0031049711 scopus 로고    scopus 로고
    • Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40-CD40 ligand signaling in atherosclerosis
    • Mach F, Schonbeck U, Sukhova GK, Bourcier T, Bonnefoy JY, Pober JS, et al. Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40-CD40 ligand signaling in atherosclerosis. Proc Natl Acad Sci USA (1997) 94:1931-6.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 1931-1936
    • Mach, F.1    Schonbeck, U.2    Sukhova, G.K.3    Bourcier, T.4    Bonnefoy, J.Y.5    Pober, J.S.6
  • 111
    • 0035824895 scopus 로고    scopus 로고
    • CD40 signaling and plaque instability
    • doi:10.1161/hh2401.101272
    • Schonbeck U, Libby P. CD40 signaling and plaque instability. Circ Res (2001) 89:1092-103. doi:10.1161/hh2401.101272.
    • (2001) Circ Res , vol.89 , pp. 1092-1103
    • Schonbeck, U.1    Libby, P.2
  • 112
    • 70350447306 scopus 로고    scopus 로고
    • The multi-functionality of CD40L and its receptor CD40 in atherosclerosis
    • doi:10.1160/TH09-01-0029
    • Lievens D, Eijgelaar WJ, Biessen EA, Daemen MJ, Lutgens E. The multi-functionality of CD40L and its receptor CD40 in atherosclerosis. Thromb Haemost (2009) 102:206-14. doi:10.1160/TH09-01-0029.
    • (2009) Thromb Haemost , vol.102 , pp. 206-214
    • Lievens, D.1    Eijgelaar, W.J.2    Biessen, E.A.3    Daemen, M.J.4    Lutgens, E.5
  • 113
    • 77954914191 scopus 로고    scopus 로고
    • B cell depletion reduces the development of atherosclerosis in mice
    • doi:10.1084/jem.20100155
    • Ait-Oufella H, Herbin O, Bouaziz JD, Binder CJ, Uyttenhove C, Laurans L, et al. B cell depletion reduces the development of atherosclerosis in mice. J Exp Med (2010) 207:1579-87. doi:10.1084/jem.20100155.
    • (2010) J Exp Med , vol.207 , pp. 1579-1587
    • Ait-Oufella, H.1    Herbin, O.2    Bouaziz, J.D.3    Binder, C.J.4    Uyttenhove, C.5    Laurans, L.6
  • 114
    • 77958125881 scopus 로고    scopus 로고
    • Conventional B2 B cell depletion ameliorates whereas its adoptive transfer aggravates atherosclerosis
    • doi:10.4049/jimmunol.1000033
    • Kyaw T, Tay C, Khan A, Dumouchel V, Cao A, To K, et al. Conventional B2 B cell depletion ameliorates whereas its adoptive transfer aggravates atherosclerosis. J Immunol (2010) 185:4410-9. doi:10.4049/jimmunol.1000033.
    • (2010) J Immunol , vol.185 , pp. 4410-4419
    • Kyaw, T.1    Tay, C.2    Khan, A.3    Dumouchel, V.4    Cao, A.5    To, K.6
  • 115
    • 80053574700 scopus 로고    scopus 로고
    • B1a B lymphocytes are atheroprotective by secreting natural IgM that increases IgM deposits and reduces necrotic cores in atherosclerotic lesions
    • doi:10.1161/CIRCRESAHA.111.248542
    • Kyaw T, Tay C, Krishnamurthi S, Kanellakis P, Agrotis A, Tipping P, et al. B1a B lymphocytes are atheroprotective by secreting natural IgM that increases IgM deposits and reduces necrotic cores in atherosclerotic lesions. Circ Res (2011) 109:830-40. doi:10.1161/CIRCRESAHA.111.248542.
    • (2011) Circ Res , vol.109 , pp. 830-840
    • Kyaw, T.1    Tay, C.2    Krishnamurthi, S.3    Kanellakis, P.4    Agrotis, A.5    Tipping, P.6
  • 116
    • 77955882476 scopus 로고    scopus 로고
    • B-cell stage and context-dependent requirements for survival signals from BAFF and the B-cell receptor
    • doi:10.1111/j.1600-065X.2010.00944.x
    • Mackay F, Figgett WA, Saulep D, Lepage M, Hibbs ML. B-cell stage and context-dependent requirements for survival signals from BAFF and the B-cell receptor. Immunol Rev (2010) 237:205-25. doi:10.1111/j.1600-065X.2010.00944.x.
    • (2010) Immunol Rev , vol.237 , pp. 205-225
    • Mackay, F.1    Figgett, W.A.2    Saulep, D.3    Lepage, M.4    Hibbs, M.L.5
  • 117
    • 0025758478 scopus 로고
    • Phenotypic and genetic characterization of a unique B lymphocyte deficiency in strain A/WySnJ mice
    • doi:10.1002/eji.1830210506
    • Miller DJ, Hayes CE. Phenotypic and genetic characterization of a unique B lymphocyte deficiency in strain A/WySnJ mice. Eur J Immunol (1991) 21:1123-30. doi:10.1002/eji.1830210506.
    • (1991) Eur J Immunol , vol.21 , pp. 1123-1130
    • Miller, D.J.1    Hayes, C.E.2
  • 118
    • 0035154624 scopus 로고    scopus 로고
    • Adventitial infiltrates associated with advanced atherosclerotic plaques: structural organization suggests generation of local humoral immune responses
    • doi:10.1002/1096-9896(2000)9999:9999<::AID-PATH774>3.0.CO;2-N
    • Houtkamp MA, de Boer OJ, van der Loos CM, van der Wal AC, Becker AE. Adventitial infiltrates associated with advanced atherosclerotic plaques: structural organization suggests generation of local humoral immune responses. J Pathol (2001) 193:263-9. doi:10.1002/1096-9896(2000)9999:9999<::AID-PATH774>3.0.CO;2-N.
    • (2001) J Pathol , vol.193 , pp. 263-269
    • Houtkamp, M.A.1    de Boer, O.J.2    van der Loos, C.M.3    van der Wal, A.C.4    Becker, A.E.5
  • 119
    • 0042624814 scopus 로고    scopus 로고
    • A conduit system distributes chemokines and small blood-borne molecules through the splenic white pulp
    • doi:10.1084/jem.20021801
    • Nolte MA, Belien JA, Schadee-Eestermans I, Jansen W, Unger WW, van Rooijen N, et al. A conduit system distributes chemokines and small blood-borne molecules through the splenic white pulp. J Exp Med (2003) 198:505-12. doi:10.1084/jem.20021801.
    • (2003) J Exp Med , vol.198 , pp. 505-512
    • Nolte, M.A.1    Belien, J.A.2    Schadee-Eestermans, I.3    Jansen, W.4    Unger, W.W.5    van Rooijen, N.6
  • 120
    • 33846320026 scopus 로고    scopus 로고
    • Role of osteoprotegerin and its ligands and competing receptors in atherosclerotic calcification
    • doi:10.2310/6650.2006.06019
    • Tintut Y, Demer L. Role of osteoprotegerin and its ligands and competing receptors in atherosclerotic calcification. J Investig Med (2006) 54:395-401. doi:10.2310/6650.2006.06019.
    • (2006) J Investig Med , vol.54 , pp. 395-401
    • Tintut, Y.1    Demer, L.2
  • 122
    • 33646441388 scopus 로고    scopus 로고
    • Enhanced T-cell expression of RANK ligand in acute coronary syndrome: possible role in plaque destabilization
    • doi:10.1161/01.ATV.0000204334.48195.6A
    • Sandberg WJ, Yndestad A, Øie E, Smith C, Ueland T, Ovchinnikova O, et al. Enhanced T-cell expression of RANK ligand in acute coronary syndrome: possible role in plaque destabilization. Arterioscler Thromb Vasc Biol (2006) 26:857-63. doi:10.1161/01.ATV.0000204334.48195.6A.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 857-863
    • Sandberg, W.J.1    Yndestad, A.2    Øie, E.3    Smith, C.4    Ueland, T.5    Ovchinnikova, O.6
  • 123
    • 77958010783 scopus 로고    scopus 로고
    • Receptor activator of nuclear factor kappaB ligand is a novel inducer of tissue factor in macrophages
    • doi:10.1161/CIRCRESAHA.110.221168
    • Kim J, Min JK, Park JA, Doh HJ, Choi YS, Rho J, et al. Receptor activator of nuclear factor kappaB ligand is a novel inducer of tissue factor in macrophages. Circ Res (2010) 107:871-6. doi:10.1161/CIRCRESAHA.110.221168.
    • (2010) Circ Res , vol.107 , pp. 871-876
    • Kim, J.1    Min, J.K.2    Park, J.A.3    Doh, H.J.4    Choi, Y.S.5    Rho, J.6
  • 124
    • 17644389199 scopus 로고    scopus 로고
    • TNF/TNFR family members in costimulation of T cell responses
    • doi:10.1146/annurev.immunol.23.021704.115839
    • Watts TH. TNF/TNFR family members in costimulation of T cell responses. Annu Rev Immunol (2005) 23:23-68. doi:10.1146/annurev.immunol.23.021704.115839.
    • (2005) Annu Rev Immunol , vol.23 , pp. 23-68
    • Watts, T.H.1
  • 125
    • 77954251861 scopus 로고    scopus 로고
    • Soluble TWEAK is markedly upregulated in patients with ST-elevation myocardial infarction and related to an adverse short-term outcome
    • doi:10.1016/j.atherosclerosis.2010.02.016
    • Chorianopoulos E, Jarr K, Steen H, Giannitsis E, Frey N, Katus HA. Soluble TWEAK is markedly upregulated in patients with ST-elevation myocardial infarction and related to an adverse short-term outcome. Atherosclerosis (2010) 211:322-6. doi:10.1016/j.atherosclerosis.2010.02.016.
    • (2010) Atherosclerosis , vol.211 , pp. 322-326
    • Chorianopoulos, E.1    Jarr, K.2    Steen, H.3    Giannitsis, E.4    Frey, N.5    Katus, H.A.6
  • 127
    • 84861303311 scopus 로고    scopus 로고
    • Lower plasma soluble TWEAK concentration in patients with newly diagnosed hypertension
    • Karadurmus N, Tapan S, Cakar M, Naharci I, Celik T, Tasci I, et al. Lower plasma soluble TWEAK concentration in patients with newly diagnosed hypertension. Clin Invest Med (2012) 35:E20-6.
    • (2012) Clin Invest Med , vol.35
    • Karadurmus, N.1    Tapan, S.2    Cakar, M.3    Naharci, I.4    Celik, T.5    Tasci, I.6


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