Tumor necrosis factor-like weak inducer of apoptosis and fibroblast growth factor-inducible 14 mediate cerebral ischemia-induced poly(ADP-ribose) polymerase-1 activation and neuronal death

Neuroscience

Volumn 171, Issue 4, 2010, Pages 1256-1264

  Haile, W B ^a   Echeverry, R ^a   Wu, F ^a   Guzman, J ^a   An, J ^b   Wu, J ^a,c   Yepes, M ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Cerebral ischemia; Fibroblast growth factor inducible 14 (Fn14); Poly(ADP ribose) polymerase 1 (PARP 1); Poly(ADP ribose) polymers (PAR); Tumor necrosis factor like weak inducer of apoptosis (TWEAK)

Indexed keywords

CASPASE 3; FIBROBLAST GROWTH FACTOR INDUCIBLE 14; GLUCOSE; GROWTH FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; OXYGEN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR LIKE WEAK INDUCER OF APOPTOSIS; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN HYPOXIA; BRAIN ISCHEMIA; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION;

ANIMALS; ANOXIA; CELL DEATH; CELLS, CULTURED; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION; GLUCOSE; HYDROGEN PEROXIDE; INFARCTION, MIDDLE CEREBRAL ARTERY; MICE; MICE, KNOCKOUT; NEURONS; OXIDANTS; POLY(ADP-RIBOSE) POLYMERASES; RECEPTORS, TUMOR NECROSIS FACTOR; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; TUMOR NECROSIS FACTORS;

EID: 78650175484     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.10.029     Document Type: Article

References (38)

1. An J., Zhang C., Polavarapu R., Zhang X., Zhang X., Yepes M. Tissue-type plasminogen activator and the low density lipoprotein receptor-related protein induce Akt phosphorylation in the ischemic brain. Blood 2008, 112:2787-2794.
2. Bover L.C., Cardo-Vila M., Kuniyasu A., Sun J., Rangel R., Takeya M., Aggarwal B.B., Arap W., Pasqualini R. A previously unrecognized protein-protein interaction between TWEAK and CD163: potential biological implications. J Immunol 2007, 178:8183-8194.
3. Chiarugi A., Moskowitz M.A. Poly(ADP-ribose) polymerase-1 activity promotes NF-kappaB-driven transcription and microglial activation: implication for neurodegenerative disorders. J Neurochem 2003, 85:306-317.
4. Chicheportiche Y., Bourdon P.R., Xu H., Hsu Y.M., Scott H., Hession C., Garcia I., Browning J.L. TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis. J Biol Chem 1997, 272:32401-32410.
5. Chicheportiche Y., Chicheportiche R., Sizing I., Thompson J., Benjamin C.B., Ambrose C., Dayer J.M. Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodies. Arthritis Res 2002, 4:126-133.
6. D'Amours D., Sallmann F.R., Dixit V.M., Poirier G.G. Gain-of-function of poly(ADP-ribose) polymerase-1 upon cleavage by apoptotic proteases: implications for apoptosis. J Cell Sci 2001, 114:3771-3778.
7. Donohue P.J., Richards C.M., Brown S.A., Hanscom H.N., Buschman J., Thangada S., Hla T., Williams M.S., Winkles J.A. TWEAK is an endothelial cell growth and chemotactic factor that also potentiates FGF-2 and VEGF-A mitogenic activity. Arterioscler Thromb Vasc Biol 2003, 23:594-600.
8. Eliasson M.J., Sampei K., Mandir A.S., Hurn P.D., Traystman R.J., Bao J., Pieper A., Wang Z.Q., Dawson T.M., Snyder S.H., Dawson V.L. Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia. Nat Med 1997, 3:1089-1095.
9. Haile W.B., Echeverry R., Wu J., Yepes M. The interaction between tumor necrosis factor-like weak inducer of apoptosis and its receptor fibroblast growth factor-inducible 14 promotes the recruitment of neutrophils into the ischemic brain. J Cereb Blood Flow Metab 2010, 30:1147-1156.
10. Harada N., Nakayama M., Nakano H., Fukuchi Y., Yagita H., Okumura K. Pro-inflammatory effect of TWEAK/Fn14 interaction on human umbilical vein endothelial cells. Biochem Biophys Res Commun 2002, 299:488-493.
11. Hassa P.O., Covic M., Hasan S., Imhof R., Hottiger M.O. The enzymatic and DNA binding activity of PARP-1 are not required for NF-kappa B coactivator function. J Biol Chem 2001, 276:45588-45597.
12. Inta I., Frauenknecht K., Dorr H., Kohlhof P., Rabsilber T., Auffarth G.U., Burkly L., Mittelbronn M., Hahm K., Sommer C., Schwaninger M. Induction of the cytokine TWEAK and its receptor Fn14 in ischemic stroke. J Neurol Sci 2008, 275:117-120.
13. Jin L., Nakao A., Nakayama M., Yamaguchi N., Kojima Y., Nakano N., Tsuboi R., Okumura K., Yagita H., Ogawa H. Induction of RANTES by TWEAK/Fn14 interaction in human keratinocytes. J Invest Dermatol 2004, 122:1175-1179.
14. Kim S.H., Kang Y.J., Kim W.J., Woo D.K., Lee Y., Kim D.I., Park Y.B., Kwon B.S., Park J.E., Lee W.H. TWEAK can induce pro-inflammatory cytokines and matrix metalloproteinase-9 in macrophages. Circ J 2004, 68:396-399.
15. Koh D.W., Dawson T.M., Dawson V.L. Mediation of cell death by poly(ADP-ribose) polymerase-1. Pharmacol Res 2005, 52:5-14.
16. Lloyd-Jones D., Adams R., Carnethon M., De S.G., Ferguson T.B., Flegal K., Ford E., Furie K., Go A., Greenlund K., Haase N., Hailpern S., Ho M., Howard V., Kissela B., Kittner S., Lackland D., Lisabeth L., Marelli A., McDermott M., Meigs J., Mozaffarian D., Nichol G., O'Donnell C., Roger V., Rosamond W., Sacco R., Sorlie P., Stafford R., Steinberger J., Thom T., Wasserthiel-Smoller S., Wong N., Wylie-Rosett J., Hong Y. Heart disease and stroke statistics-2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2009, 119:480-486.
17. Lynch C.N., Wang Y.C., Lund J.K., Chen Y.W., Leal J.A., Wiley S.R. TWEAK induces angiogenesis and proliferation of endothelial cells. J Biol Chem 1999, 274:8455-8459.
18. Nakayama M., Ishidoh K., Kayagaki N., Kojima Y., Yamaguchi N., Nakano H., Kominami E., Okumura K., Yagita H. Multiple pathways of TWEAK-induced cell death. J Immunol 2002, 168:734-743.
19. Paxinos G., Franklin K.B.J. The mouse brain in stereotaxic coordinates 2001, 1-93. Academic Press, San Diego, CA.
20. Polavarapu R., Gongora M.C., Winkles J.A., Yepes M. Tumor necrosis factor-like weak inducer of apoptosis increases the permeability of the neurovascular unit through nuclear factor-kappaB pathway activation. J Neurosci 2005, 25:10094-10100.
21. Polavarapu R., Gongora M.C., Yi H., Ranganthan S., Lawrence D.A., Strickland D., Yepes M. Tissue-type plasminogen activator-mediated shedding of astrocytic low-density lipoprotein receptor-related protein increases the permeability of the neurovascular unit. Blood 2007, 109:3270-3278.
22. Polek T.C., Talpaz M., Darnay B.G., Spivak-Kroizman T. TWEAK mediates signal transduction and differentiation of RAW264.7 cells in the absence of Fn14/TweakR. Evidence for a second TWEAK receptor. J Biol Chem 2003, 278:32317-32323.
23. Potrovita I., Zhang W., Burkly L., Hahm K., Lincecum J., Wang M.Z., Maurer M.H., Rossner M., Schneider A., Schwaninger M. Tumor necrosis factor-like weak inducer of apoptosis-induced neurodegeneration. J Neurosci 2004, 24:8237-8244.
24. Saas P., Boucraut J., Walker P.R., Quiquerez A.L., Billot M., Desplat-Jego S., Chicheportiche Y., Dietrich P.Y. TWEAK stimulation of astrocytes and the proinflammatory consequences. Glia 2000, 32:102-107.
25. Scaife C.L., Kuang J., Wills J.C., Trowbridge D.B., Gray P., Manning B.M., Eichwald E.J., Daynes R.A., Kuwada S.K. Nuclear factor kappaB inhibitors induce adhesion-dependent colon cancer apoptosis: implications for metastasis. Cancer Res 2002, 62:6870-6878.
26. Schneider A., Martin-Villalba A., Weih F., Vogel J., Wirth T., Schwaninger M. NF-kappaB is activated and promotes cell death in focal cerebral ischemia. Nat Med 1999, 5:554-559.
27. Schneider P., Schwenzer R., Haas E., Muhlenbeck F., Schubert G., Scheurich P., Tschopp J., Wajant H. TWEAK can induce cell death via endogenous TNF and TNF receptor 1. Eur J Immunol 1999, 29:1785-1792.
28. Tran N.L., McDonough W.S., Donohue P.J., Winkles J.A., Berens T.J., Ross K.R., Hoelzinger D.B., Beaudry C., Coons S.W., Berens M.E. The human Fn14 receptor gene is up-regulated in migrating glioma cells in vitro and overexpressed in advanced glial tumors. Am J Pathol 2003, 162:1313-1321.
29. Tran N.L., McDonough W.S., Savitch B.A., Sawyer T.F., Winkles J.A., Berens M.E. The tumor necrosis factor-like weak inducer of apoptosis (TWEAK)-fibroblast growth factor-inducible 14 (Fn14) signaling system regulates glioma cell survival via NFkappaB pathway activation and BCL-XL/BCL-W expression. J Biol Chem 2005, 280:3483-3492.
30. van Wijk S.J., Hageman G.J. Poly(ADP-ribose) polymerase-1 mediated caspase-independent cell death after ischemia/reperfusion. Free Radic Biol Med 2005, 39:81-90.
31. Vince J.E., Chau D., Callus B., Wong W.W., Hawkins C.J., Schneider P., McKinlay M., Benetatos C.A., Condon S.M., Chunduru S.K., Yeoh G., Brink R., Vaux D.L., Silke J. TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha. J Cell Biol 2008, 182:171-184.
32. Wiley S.R., Cassiano L., Lofton T., Davis-Smith T., Winkles J.A., Lindner V., Liu H., Daniel T.O., Smith C.A., Fanslow W.C. A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis. Immunity 2001, 15:837-846.
33. Winkles J.A. The TWEAK-Fn14 cytokine-receptor axis: discovery, biology and therapeutic targeting. Nat Rev Drug Discov 2008, 7:411-425.
34. Xu H., Okamoto A., Ichikawa J., Ando T., Tasaka K., Masuyama K., Ogawa H., Yagita H., Okumura K., Nakao A. TWEAK/Fn14 interaction stimulates human bronchial epithelial cells to produce IL-8 and GM-CSF. Biochem Biophys Res Commun 2004, 318:422-427.
35. Yepes M., Brown S.A., Moore E.G., Smith E.P., Lawrence D.A., Winkles J.A. A soluble Fn14-Fc decoy receptor reduces infarct volume in a murine model of cerebral ischemia. Am J Pathol 2005, 166:511-520.
36. Yu Z., Zhou D., Bruce-Keller A.J., Kindy M.S., Mattson M.P. Lack of the p50 subunit of nuclear factor-kappaB increases the vulnerability of hippocampal neurons to excitotoxic injury. J Neurosci 1999, 19:8856-8865.
37. Zhang X., Polavarapu R., She H., Mao Z., Yepes M. Tissue-type plasminogen activator and the low-density lipoprotein receptor-related protein mediate cerebral ischemia-induced nuclear factor-kappaB pathway activation. Am J Pathol 2007, 171:1281-1290.
38. Zhang X., Winkles J.A., Gongora M.C., Polavarapu R., Michaelson J.S., Hahm K., Burkly L., Friedman M., Li X.J., Yepes M. TWEAK-Fn14 pathway inhibition protects the integrity of the neurovascular unit during cerebral ischemia. J Cereb Blood Flow Metab 2007, 27:534-544.