TWEAK-Fn14 pathway inhibition protects the integrity of the neurovascular unit during cerebral ischemia

Journal of Cerebral Blood Flow and Metabolism

Volumn 27, Issue 3, 2007, Pages 534-544

  Zhang, Xiaohui ^a   Winkles, Jeffrey A ^b   Gongora, Maria C ^a   Polavarapu, Rohini ^a   Michaelson, Jennifer S ^c   Hahm, Kyungmin ^c   Burkly, Linda ^c   Friedman, Meyer ^d   Li, Xiao Jiang ^d   Yepes, Manuel ^a,e  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c BIOGEN   (United States)

^d CLARK ATLANTA UNIVERSITY   (United States)

^e Center for Neurodegenerative Disease   (United States)

Author keywords

Blood brain barrier; Cerebral ischemia; Cytokines; Neurovascular unit

Indexed keywords

CELL SURFACE RECEPTOR; EVANS BLUE; FN14 FC FUSION PROTEIN; GELATINASE B; HYBRID PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LAMININ; PROTEIN FN14; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR LIKE WEAK INDUCER OF APOPTOSIS; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD VESSEL; BRAIN ISCHEMIA; CONTROLLED STUDY; ENZYME ACTIVATION; EXTRAVASATION; GENETIC DISORDER; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOTOR PERFORMANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; WILD TYPE;

ANIMALS; ASTROCYTES; BLOOD-BRAIN BARRIER; BLOTTING, WESTERN; BRAIN; BRAIN EDEMA; BRAIN ISCHEMIA; CAPILLARY PERMEABILITY; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENDOTHELIAL CELLS; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOHISTOCHEMISTRY; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MATRIX METALLOPROTEINASE 9; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; NF-KAPPA B; RECEPTORS, TUMOR NECROSIS FACTOR; RECOVERY OF FUNCTION; TUMOR NECROSIS FACTORS;

EID: 33847209525     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jcbfm.9600368     Document Type: Article

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