Involvement of TWEAK in interferon γ-stimulated monocyte cytotoxicity

Journal of Experimental Medicine

Volumn 192, Issue 9, 2000, Pages 1373-1379

  Nakayama, Masafumi ^a   Kayagaki, Nobuhiko ^a,b   Yamaguchi, Noriko ^a,b   Okumura, Ko ^a,b   Yagita, Hideo ^a,b  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Cytotoxicity; IFN ; Monocyte; TRAIL; TWEAK

Indexed keywords

ALPHA INTERFERON; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; MONOCLONAL ANTIBODY; PROTEIN TWEAK; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; MONOCYTE; MONONUCLEAR CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD; APOPTOSIS REGULATORY PROTEINS; CARCINOMA, SQUAMOUS CELL; CARRIER PROTEINS; CELLS, CULTURED; CYTOTOXICITY TESTS, IMMUNOLOGIC; CYTOTOXICITY, IMMUNOLOGIC; FLOW CYTOMETRY; HUMANS; INTERFERON TYPE II; INTERFERON-ALPHA; LIPOPOLYSACCHARIDES; MEMBRANE GLYCOPROTEINS; MONOCYTES; RECOMBINANT FUSION PROTEINS; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA; TUMOR NECROSIS FACTORS;

EID: 0034613732     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.192.9.1373     Document Type: Article

References (26)

1. Death receptors: Signaling and modulation
2. Apoptosis by death factor
3. Cell death: TRAIL and its receptors
4. TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis
5. Identification of a ligand for the death-domain-containing receptor Apo3
6. TWEAK can induce cell death via endogenous TNF and TNF receptor 1
7. TWEAK induces angiogenesis and proliferation of endothelial cells
8. Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95
9. Tumor necrosis factor is an important mediator of tumor cell killing by human monocytes
10. Activation of human monocyte cytotoxicity by natural and recombinant immune interferon
11. Nitric oxide and macrophage function
12. Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): Analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages
13. Monocyte-mediated tumoricidal activity via the tumor necrosis factor-related cytokine, TRAIL
14. + T cell-mediated cytotoxicity
15. Metalloproteinase-mediated release of human Fas ligand
16. Polymorphism of murine Fas ligand that affects the biological activity
17. Processing of tumour necrosis factor-α precursor by metalloproteinases
18. Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumor effects of type I IFNs
19. Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells
20. Fas ligand in human serum
21. + T cell killing of antigen-presenting macrophages
22. The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor
23. Down-regulation of Fas ligand by shedding
24. IFN-γ- and cell-to-cell contact-dependent cytotoxicity of allograft-induced macrophages against syngeneic tumor cells and cell lines: An application of allografting to cancer treatment
25. Phenotype and functions of intratumoral macrophages
26. Autologous human macrophages and anti-tumour cell therapy