Prefrontal cortical GABAergic dysfunction contributes to age-related working memory impairment

Journal of Neuroscience

Volumn 34, Issue 10, 2014, Pages 3457-3466

  Bañuelos, Cristina ^a   Sofia Beas, B ^a   McQuail, Joseph A ^a   Gilbert, Ryan J ^a   Frazier, Charles J ^a,b   Setlow, Barry ^a   Bizon, Jennifer L ^a,b  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

Aging; CGP55845; Executive function; GABA(B) receptor; Inhibition; Prefrontal cortex

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; BENZYL [3 [[1 (3, 4 DICHLOROPHENYL) ETHYL] AMINO] 2 HYDROXYPROPYL] PHOSPHINIC ACID; GLUTAMATE DECARBOXYLASE 67; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; UNCLASSIFIED DRUG; VESICULAR INHIBITORY AMINO ACID TRANSPORTER;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANNULATION; CENTRAL NERVOUS SYSTEM DISEASE; DELAYED RESPONSE TASK; EXPERIMENTAL BEHAVIORAL TEST; GABAERGIC SYSTEM; HISTOLOGY; IMMUNOBLOTTING; INFANT; MALE; NEUROTRANSMITTER RELEASE; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING; WORKING MEMORY IMPAIRMENT;

AGING; CGP55845; EXECUTIVE FUNCTION; GABA(B) RECEPTOR; INHIBITION; PREFRONTAL CORTEX;

AGING; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; GABA-B RECEPTOR ANTAGONISTS; MALE; MEMORY DISORDERS; MEMORY, SHORT-TERM; PREFRONTAL CORTEX; RATS; RATS, INBRED F344; REACTION TIME; RECEPTORS, GABA-B;

EID: 84895419110     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5192-13.2014     Document Type: Article

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