Potent, orally active GABA(B) receptor antagonists

Pharmacology Communications

Volumn 8, Issue 2-3, 1996, Pages 127-133

  Froestl, W ^a   Mickel, S J ^a   Schmutz, M ^a   Bittiger, H ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Blood brain barrier; GABA(B) receptor antagonists; In vivo tests; Intestinal epithelial barrier; Lipophilicity; Log P

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; [3 (3,4 DICHLOROBENZYLAMINO)PROPYL](DIETHOXYMETHYL)PHOSPHINIC ACID; BACLOFEN; BENZYL[3 [[1 (3,4 DICHLOROPHENYL)ETHYL]AMINO] 2 HYDROXYPROPYL]PHOSPHINIC ACID; BUFFER; CGP 53680; CGP 54422; CGP 54624; CGP 54626; PHACLOFEN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; BODY TEMPERATURE; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; HYDROPHILICITY; LIPOPHILICITY; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PH; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0029994222     PISSN: 10604456     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)