Cognitive impairment in aged rhesus monkeys associated with monoamine receptors in the prefrontal cortex

Behavioural Brain Research

Volumn 160, Issue 2, 2005, Pages 208-221

  Moore, Tara L ^a   Schettler, Stephen P ^a   Killiany, Ronald J ^a   Herndon, James G ^b   Luebke, Jennifer I ^a   Moss, Mark B ^a,b   Rosene, Douglas L ^a,b  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

Aging; Cognition; Dopamine; Norepinephrine; Prefrontal cortex; Receptors; Rhesus

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR; DOPAMINE 1 RECEPTOR; DOPAMINE RECEPTOR; NEUROTRANSMITTER;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING ASSAY; COGNITION; COGNITIVE DEFECT; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; IN VITRO STUDY; MALE; MENTAL PERFORMANCE; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; RECEPTOR BINDING; RECOGNITION; RHESUS MONKEY; STATISTICAL SIGNIFICANCE; TASK PERFORMANCE;

EID: 18044385752     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbr.2004.12.003     Document Type: Article

References (77)

1. M. Albert, and M.B. Moss Cognition normal aging A. Peters J. Morrison Cerebral cortex vol. 14 1999 New York Plenum Press
2. C. Aoki, C. Venkatesan, C.G. Go, R. Forman, and H. Kurose Cellular and subcellular sites for noradrenergic action in the monkey dorsolateral prefrontal cortex as revealed by the immunocytochemical localization of noradrenergic receptors and axons Cereb Cortex 8 1998 269 277
3. A.F.T. Arnsten, and P.S. Goldman-Rakic Alpha-2 adrenergic mechanisms in prefrontal cortex associated with cognitive decline in aged non-human primates Science 230 1985 1273 1276
4. A.F.T. Arnsten, and P.S. Goldman-Rakic Analysis of α-2 adrenergic agonist effects on the delayed non-match-to-sample performance of aged rhesus monkeys Neurobiol Aging 11 1990 583 590
5. A.F.T. Arnsten, and T.A. Contant Alpha-2 adrenergic agonists decrease distractibility in aged monkeys performing the delayed response task Psychopharmacology 108 1992 159 169
6. A.F.T. Arnsten Catecholamine mechanisms in age-related cognitive decline Neurobiol Aging 14 1993 639 641
7. A.F.T. Arnsten, and J.X. Cai Postsynaptic alpha-2 receptor stimulation improves memory in aged monkeys: indirect effects of yohimbine versus direct effects of clonidine Neurobiol Aging 14 6 1993 597 603
8. A.F.T. Arnsten, J.X. Cai, B.L. Murphy, and P.S. Goldman-Rakic Dopamine D1 receptor mechanisms in the cognitive performance of young adult and aged monkeys Psychopharmacology 116 1994 143 151
9. A.F.T. Arnsten, and J.D. Jentsch The Alpha-1 adrenergic agonist, cirazoline impairs spatial working memory performance in aged monkeys Pharmacol. Biochem. Behav 58 1 1997 55 59
10. A.F.T. Arnsten, J.C. Steere, J.D. Jentsch, and B.M. Li Noradrenergic influences on prefrontal cortical cognitive function: opposing actions at postjunctional alpha 1 versus alpha 2 adrenergic receptors Adv Pharmacol 42 1998 764 767
11. A.F.T. Arnsten, and P.S. Goldman-Rakic Noradrenergic mechanisms in age-related cognitive decline J Neural Transm Suppl 24 1987 317 324
12. A.F.T. Arnsten, R. Mathew, R. Ubriani, J.R. Taylor, and B. Li α-1 noradrenergic receptor stimulation impairs prefrontal cortical cognitive function Biol Psychiatry 45 1999 26 31
13. J. Bachevalier Behavioral changes in aged rhesus monkeys Neurobiol Aging 14 1993 619 621
14. M.F. Beal, L.C. Walker, E. Story, L. Segar, D.L. Price, and L.C. Cork Neurotransmitters in neocortex of aged rhesus monkeys Neurobiol Aging 12 1991 407 412
15. C.W. Berridge, A.F. Arnsten, and S.L. Foote Noradrenergic modulation of cognitive function: clinical implications of anatomical electrophysiological and behavioral studies in animal models Psychol Med 23 3 1993 557 564
16. M.H. Bigham, and M.S. Lidow Adrenergic and serotonergic receptors in aged monkey neocortex Neurobiol Aging 16 1 1995 91 104
17. T.J. Brozoski, R.M. Brown, H.E. Rosvold, and P.S. Goldman Cognitive deficits caused by regional depletion of dopamine in prefrontal cortex of rhesus monkey Science 205 1979 929 931
18. Chang YM, Rosene DL, Killiany RJ, Mangiamele LA, Luebke JI. Increased action potential firing rates of layer 2/3 pyramidal cells in the prefrontal cortex are significantly related to cognitive performance in aged monkeys. Cereb Cortex, 2004; Epub.
19. N.M. Fristoe, T.A. Salthouse, and J.L. Woodward Examination of age-related deficits on the Wisconsin card sorting task Neuropsychology 11 3 1997 428 436
20. J.M. Fuster The prefrontal cortex anatomy physiology and neuropsychology of the frontal lobe 3rd ed. 1997 Lippincott-Raven New York
21. P.S. Goldman-Rakic, E.C. Muly, and G.V. Williams D(1) receptors in prefrontal cells and circuits Brain Res Brain Res Rev 31 2-3 2000 295 301
22. P.S. Goldman-Rakic, and R.M. Brown Regional changes of monoamines in cerebral cortex and subcortical structures of aging Neuroscience 6 2 1981 177 187
23. P.S. Goldman, and H.E. Rosvold Localization of function within the dorsolateral prefrontal cortex of the rhesus monkey Exp Neurol 27 1970 291 304
24. P.S. Goldman-Rakic, M.S. Lidow, and D.W. Gallager Overlap of dopaminergic, adrenergic, and serotoninergic receptors and complementarity of their subtypes in primates prefrontal cortex J Neurosci 10 7 1990 2125 2138
25. C.G. Gottfries Neurochemical aspects on aging and diseases with cognitive impairment J Neurosci Res 27 1990 541 547
26. T. Hanninen, M. Hallikainen, K. Koivisto, K. Partanen, M.P. Laakso, and P.J. Riekkinen Decline of frontal lobe functions in subjects with age associated memory impairments Neurology 48 1997 148 153
27. S.I. Harik, S.M. Sromek, and R.N. Kalaria Alpha- and beta-adrenergic receptors of the rat cerebral cortex and cerebral microvessels in aging, and their response to denervation Neurobiol Aging 12 5 1991 567 573
28. J.G. Herndon, M.B. Moss, D.L. Rosene, and R.J. Killiany Patterns of cognitive decline in aged rhesus monkeys Behav Brain Res 87 1 1997 25 34
29. G. Hochanadel, and E. Kaplan Neuropsychology of normal aging M.A. Albert JE. Knoefel Clinical neurology of aging 1984 Guillford Press New York 231 244
30. Y. Ishida, T. Shirokawa, O. Miyaishi, Y. Komatsu, and K. Isobe Age-dependent changes in projections from locus coeruleus to hippocampus dentate gyrus and frontal cortex Eur J Neurosci 12 4 2000 1263 1270
31. Y. Ishida, T. Shirokawa, Y. Komatsu, and B. Isobe Changes in cortical noradrenergic axon terminals of locus coeruleus neurons in aged F344 rats Neurosci Lett 307 2001 197 199
32. Y. Ishida, T. Shirokawa, O. Myaishi, Y. Komatsu, and K. Isobe Age-dependent changes in noradrenergic innervations of the frontal cortex of F344 rats Neurobiol Aging 22 2001 283 386
33. Institute of Laboratory Animals Resources Commission on Life Sciences. Guide for the Care and Use of Laboratory Animals. Washington, DC: National Academy Press; 1996.
34. B.A. Keys, and D.A. White Exploring the relationship between age, executive abilities and psychomotor speed J Int Neuropsychol Soc 6 2000 76 82
35. A. Lacreuse, J.G. Herndon, R.J. Killiany, D.L. Rosene, and M.B. Moss Spatial cognition in rhesus monkeys: male superiority declines with age Horm Behav 36 1 1996 70 76
36. Z.C. Lai, M.B. Moss, R.J. Killiany, D.L. Rosene, and J.G. Herndon Executive system dysfunction in the aged monkey: spatial and object reversal learning Neurobiol Aging 16 6 1995 947 954
37. D.A. Lewis, and J.H. Morrison Noradrenergic innervation of monkey prefrontal cortex: a dopamine-B-hydroxylase immunohistochemical study J Comp Neurol 282 1989 317 330
38. D.A. Lewis The catecholaminergic innervation of primate prefrontal cortex J Neural Transm 36 Suppl. 1992 179 200
39. D.J. Libon, G. Glosser, B.L. Malamut, E. Kaplan, E. Goldberg, and R. Swenson Age, executive functions, and visuospatial functioning in healthy older adults Neuropsychology 8 1 1994 38 43
40. J.I. Luebke, Y-M. Chang, T.L. Moore, and D.L. Rosene Normal aging results in decreased synaptic excitation and increased synaptic inhibition of layer 2/3 pyramidal cells in the monkey prefrontal cortex Neuroscience 125 2004 277 288
41. Z. Mao, A.F.T. Arnsten, and B. Li Local infusion of an α-1 adrenergic agonist into the prefrontal cortex impairs spatial working memory performance in monkeys Biol Psychiatry 46 1999 1259 1265
42. B. Milner Aspects of human frontal lobe H.H. Jasper S. Riggio P.S. Goldman-Rakic Function epilepsy and the functional anatomy of the frontal lobe 1995 Raven Press New York
43. B. Milner, S. Corkin, and H.L. Teuber Further analysis of the hippocampal amnesic syndrome: 14 year follow-up study of H.M Neuropsychologia 6 1968 215 234
44. M. Mishkin Perseveration of central sets after frontal lesions in monkeys J.M. Warren K. Akert The frontal granular cortex and behavior 1964 McGraw-Hill New York 219 241
45. W. Mittenberg, M. Seidenberg, D.S. O'Leary, and D.V. DiGiulio Changes in cerebral functioning associated with normal aging J Exp Neuropsychol 11 6 1989 918 932
46. G.H. Moll, C. Mehnert, M. Wicker, N. Bock, A. Rothenberger, and E. Ruther Age-associated changes in the densities of presynaptic monoamine transporters in different regions of the rat brain from early juvenile life to late adulthood Dev Brain Res 119 2000 251 257
47. T.L. Moore, R.J. Killiany, J.G. Herndon, D.L. Rosene, and M.B. Moss Impairment in abstraction and set shifting in aged rhesus monkeys Neurobiol Aging 24 1 2003 125 134
48. T.L. Moore, R.J. Killiany, D.L. Rosene, and M.B. Moss Lesions of dorsal prefrontal cortex produce an executive function deficit in the rhesus monkey Soc Neurosci Abstract 2001
49. M.B. Moss, R.J. Killiany, Z.C. Lai, D.L. Rosene, and J.G. Herndon Recognition memory span in rhesus monkeys of advanced age Neurobiol Aging 18 1 1997 13 19
50. K.M. O'Boyle, and J.L. Waddington Loss of rat striatal dopamine receptors with ageing is selective for D-2 but no D-1 sites: association with increased non-specific binding of the D-1 ligand [3H] piflutixol Eur J Pharmacol 105 1984 171 174
51. K.A. O'Donnell, P.R. Rapp, and P.R. Hof Preservation of prefrontal cortical volume in behaviorally characterized aged macaque monkeys Exp Neurol 160 1 1999 300 310
52. A. Peters, D.L. Rosene, M.B. Moss, T.L. Kemper, C.R. Abraham, and J. Tigges Neurobiological bases of age-related cognitive decline in the rhesus monkey J Neuropathol Exp Neurol 55 8 1996 861 874
53. A. Peters Structural changes that occur during normal aging of primate cerebral hemispheres Neurosci Biobehav Rev 26 2002 733 741
54. A. Peters, and C. Sethares Is there remyelination during aging of the primate central nervous system? J Comp Neurol 460 2 2003 238 254
55. A. Peters, and C. Sethares Aging and the myelinated fibers in prefrontal cortex and corpus callosum of the monkey J Comp Neurol 442 3 2002 277 291
56. A. Peters, and C. Sethares The effects of age on the cells in layer 1 of primate cerebral cortex Cereb Cortex 12 1 2002 27 36
57. A.P. Peters, J.H. Morrison, D.L. Rosene, and B.T. Hyman Feature article: are neurons lost from the primate cerebral cortex during normal aging? Cereb Cortex 8 4 1998 295 300
58. S.K. Presty, J. Bachevalier, L.C. Walker, R.G. Strruble, D.L. Price, and M. Mishkin Age differences in recognition memory of the rhesus monkey (Macaca mulatta) Neurobiol Aging 8 1987 435 440
59. P. Rabbitt, and C. Lowe Patterns of cognitive ageing Psychol Res 63 3-4 2000 308 316
60. P. Rapp Neuropsychological analysis of learning and memory in the aged nonhuman primate Neurobiol Aging 14 1993 627 629
61. P.R. Rapp Visual discrimination and reversal learning in the aged monkey (Macaca mulatta) Behav Neurosci 104 6 1990 876 884
62. P.R. Rapp, and D.G. Amaral Evidence for task-dependent memory dysfunction in the aged monkey J Neurosci 9 10 1989 3568 3576
63. D.L. Rosene, and T.J. Nicholson Neurotransmitter receptor changes in the hippocampus and cerebral cortex in normal aging E.G. Jones A. Peters J.H. Morrison Cerebral cortex, neurodegenerative and age-related changes in cerebral cortex 14 1999 Kluwer Academic/Plenum Publishers New York 111 128
64. T. Sawaguchi, and P.S. Goldman-Rakic D1 Dopamine receptors in prefrontal cortex: involvement in working memory Science 251 1991 947 950
65. T. Sawaguchi, M. Matsumura, and K. Kubota Effects of dopamine antagonists on neuronal activity related to a delayed response task in monkey prefrontal cortex J Comp Neurol 63 6 1990 1401 1411
66. T. Shirokawa, Y. Ishida, and K. Isobe Changes in electrophysiological properties of axon terminals of locus coeruleus neurons with age in F344 rat Neurosci Lett 289 2000 69 71
67. Z. Siddiqi, T.L. Kemper, and R.J. Killiany Age related neuronal loss from the nigra-pars compacta and ventral tegmental area of the rhesus monkey J Neuropathol Exp Neurol 58 9 1999 959 971
68. D.E. Smith, P.R. Rapp, H.M. McKay, J.A. Roberts, and M.H. Tuszynski Memory impairment in aged primates is associated with focal death of cortical neurons and atrophy of subcortical neurons J Neurosci 24 18 2004 4373 4381
69. J.C. Steere, and AF.T. Arnsten The alpha-2 noradrenergic receptor agonist guanfacine improves visual object discrimination reversal performance in aged rhesus monkeys Behav Neurosci 111 5 1997 883 891
70. T. Suhara, H. Fukuda, O. Inoue, T. Itoh, K. Suzuki, and T. Yamasaki Age related changes in human D1 dopamine receptors measures by positron emission tomography Psychopharmacology 103 1991 41 45
71. A.M. Thierry, S. Pirot, Y. Gioanni, and J. Glowinski Dopamine function in the prefrontal cortex Adv Pharmacol 42 1998 717 720
72. J. Tigges, T.P. Gordon, H.M. McClure, E.C. Hall, and A. Peters Survival rate and life span of rhesus monkeys at the Yerkes regional primate research center Am J Primatol 15 1988 263 273
73. J.L. Venero, A. Machado, and J. Cano Effect of ageing on monoamine turnover in the prefrontal cortex of rats Mech Ageing Dev 72 2 1993 105 118
74. M.L. Voytko Impairments in acquisition and reversals of two-choice discriminations by aged rhesus monkeys Neurobiol Aging 20 6 1999 617 627
75. G.L. Wenk, D.J. Pierce, R. Struble, D.L. Price, and L.C. Cork Age-related changes in multiple neurotransmitters systems in the monkey brain Neurobiol Aging 10 1989 11 19
76. R.L. West An application of prefrontal cortex function theory to cognitive aging Psychol Bull 120 2 1996 272 292
77. G.V. Williams, and P.S. Goldman-Rakic Modulation of memory fields by dopamine D1 receptors in prefrontal cortex Nature 376 6541 1995 572 575