메뉴 건너뛰기




Volumn 90, Issue 4, 2003, Pages 2690-2701

GABA transporter-1 (GAT1)-deficient mice: Differential tonic activation of GABAA versus GABAB receptors in the hippocampus

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID TRANSPORTER 1; CARRIER PROTEIN; GLUTAMATE DECARBOXYLASE; NEUROTRANSMITTER; PRESYNAPTIC RECEPTOR; UNCLASSIFIED DRUG;

EID: 0142058598     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.00240.2003     Document Type: Article
Times cited : (199)

References (57)
  • 1
    • 0035057513 scopus 로고    scopus 로고
    • Distinct functional and pharmacological properties of tonic and quantal inhibitory postsynaptic currents mediated by gamma-aminobutyric acid(A) receptors in hippocampal neurons
    • Bai D, Zhu G, Pennefather P, Jackson MF, MacDonald JF, and Orser BA. Distinct functional and pharmacological properties of tonic and quantal inhibitory postsynaptic currents mediated by gamma-aminobutyric acid(A) receptors in hippocampal neurons. Mol Pharmacol 59: 814-824, 2001.
    • (2001) Mol Pharmacol , vol.59 , pp. 814-824
    • Bai, D.1    Zhu, G.2    Pennefather, P.3    Jackson, M.F.4    MacDonald, J.F.5    Orser, B.A.6
  • 2
    • 0033538546 scopus 로고    scopus 로고
    • A significant part of native gamma-aminobutyric acid A receptors containing alpha 4 subunits do not contain gamma or delta subunits
    • Bencsits E, Ebert V, Tretter V, and Sieghart W. A significant part of native gamma-aminobutyric acid A receptors containing alpha4 subunits do not contain gamma or delta subunits. J Biol Chem 274: 19613-19616, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 19613-19616
    • Bencsits, E.1    Ebert, V.2    Tretter, V.3    Sieghart, W.4
  • 3
    • 0030272426 scopus 로고    scopus 로고
    • GABA transporter heterogeneity: Pharmacology and cellular localization
    • Borden LA. GABA transporter heterogeneity: pharmacology and cellular localization. Neurochem Int 29: 335-356, 1996.
    • (1996) Neurochem Int , vol.29 , pp. 335-356
    • Borden, L.A.1
  • 5
    • 0035804244 scopus 로고    scopus 로고
    • Adaptive regulation of neuronal excitability by a voltage-independent potassium conductance
    • Brickley SG, Revilla V, Cull-Candy SG, Wisden W, and Farrant M. Adaptive regulation of neuronal excitability by a voltage-independent potassium conductance. Nature 409: 88-92, 2001.
    • (2001) Nature , vol.409 , pp. 88-92
    • Brickley, S.G.1    Revilla, V.2    Cull-Candy, S.G.3    Wisden, W.4    Farrant, M.5
  • 6
    • 0037185248 scopus 로고    scopus 로고
    • Intact sorting, targeting, and clustering of gamma-aminobutyric acid A receptor subtypes in hippocampal neurons in vitro
    • Brunig I, Scotti E, Sidler C, and Fritschy JM. Intact sorting, targeting, and clustering of gamma-aminobutyric acid A receptor subtypes in hippocampal neurons in vitro. J Comp Neurol 443: 43-55, 2002.
    • (2002) J Comp Neurol , vol.443 , pp. 43-55
    • Brunig, I.1    Scotti, E.2    Sidler, C.3    Fritschy, J.M.4
  • 7
    • 0028020417 scopus 로고
    • A GABA transporter operates asymmetrically and with variable stoichiometry
    • Cammack JN, Rakhilin SV, and Schwartz EA. A GABA transporter operates asymmetrically and with variable stoichiometry. Neuron 13: 949-960, 1994.
    • (1994) Neuron , vol.13 , pp. 949-960
    • Cammack, J.N.1    Rakhilin, S.V.2    Schwartz, E.A.3
  • 8
    • 0037444452 scopus 로고    scopus 로고
    • Coexistence of excitatory and inhibitory GABA synapses in the cerebellar interneuron network
    • Chavas J and Marty A. Coexistence of excitatory and inhibitory GABA synapses in the cerebellar interneuron network. J Neurosci 23: 2019-2031, 2003.
    • (2003) J Neurosci , vol.23 , pp. 2019-2031
    • Chavas, J.1    Marty, A.2
  • 9
    • 0033741515 scopus 로고    scopus 로고
    • Endogenous regulators of G protein signaling proteins regulate presynaptic inhibition at rat hippocampal synapses
    • Chen H and Lambert NA. Endogenous regulators of G protein signaling proteins regulate presynaptic inhibition at rat hippocampal synapses. Proc Natt Acad Sci USA 97: 12810-12815, 2000.
    • (2000) Proc Natt Acad Sci USA , vol.97 , pp. 12810-12815
    • Chen, H.1    Lambert, N.A.2
  • 10
    • 0036897386 scopus 로고    scopus 로고
    • Number, density, and surface/cytoplasmic distribution of GABA transporters at presynaptic structures of knock-in mice carrying GABA transporter subtype 1-green fluorescent protein fusions
    • Chiu CS, Jensen K, Sokolova I, Wang D, Li M, Deshpande P, Davidson N, Mody I, Quick MW, Quake SR, and Lester HA. Number, density, and surface/cytoplasmic distribution of GABA transporters at presynaptic structures of knock-in mice carrying GABA transporter subtype 1-green fluorescent protein fusions. J Neurosci 22: 10251-10266, 2002.
    • (2002) J Neurosci , vol.22 , pp. 10251-10266
    • Chiu, C.S.1    Jensen, K.2    Sokolova, I.3    Wang, D.4    Li, M.5    Deshpande, P.6    Davidson, N.7    Mody, I.8    Quick, M.W.9    Quake, S.R.10    Lester, H.A.11
  • 11
    • 0032557811 scopus 로고    scopus 로고
    • Neuronal and glial localization of GAT-1, a high-affinity gamma-aminobutyric acid plasma membrane transporter, in human cerebral cortex: With a note on its distribution in monkey cortex
    • Conti F, Melone M, De Biasi S, Minelli A, Brecha NC, and Ducati A. Neuronal and glial localization of GAT-1, a high-affinity gamma-aminobutyric acid plasma membrane transporter, in human cerebral cortex: with a note on its distribution in monkey cortex. J Comp Neurot 396: 51-63, 1998.
    • (1998) J Comp Neurot , vol.396 , pp. 51-63
    • Conti, F.1    Melone, M.2    De Biasi, S.3    Minelli, A.4    Brecha, N.C.5    Ducati, A.6
  • 13
    • 0033884270 scopus 로고    scopus 로고
    • GABA-level increasing and anticonvulsant effects of three different GABA uptake inhibitors
    • Dalby NO. GABA-level increasing and anticonvulsant effects of three different GABA uptake inhibitors. Neuropharmacology 39: 2399-2407, 2000.
    • (2000) Neuropharmacology , vol.39 , pp. 2399-2407
    • Dalby, N.O.1
  • 15
    • 0035101820 scopus 로고    scopus 로고
    • Evolving concepts in G-protein-coupled receptor endocytosis: The role in receptor desensitization and signaling
    • Ferguson SS. Evolving concepts in G-protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol Rev 53: 1-24, 2001.
    • (2001) Pharmacol Rev , vol.53 , pp. 1-24
    • Ferguson, S.S.1
  • 16
    • 0035854117 scopus 로고    scopus 로고
    • Efficacy of background GABA uptake in rat hippocampal slices
    • Frahm C, Engel D, and Draguhn A. Efficacy of background GABA uptake in rat hippocampal slices. Neuroreport 12: 1593-1596, 2001.
    • (2001) Neuroreport , vol.12 , pp. 1593-1596
    • Frahm, C.1    Engel, D.2    Draguhn, A.3
  • 17
    • 0034698496 scopus 로고    scopus 로고
    • Presence of gamma-aminobutyric acid transporter mRNA in interneurons and principal cells of rat hippocampus
    • Frahm C, Engel D, Piechotta A, Heinemann U, and Draguhn A. Presence of gamma-aminobutyric acid transporter mRNA in interneurons and principal cells of rat hippocampus. Neurosci Lett 288: 175-178, 2000.
    • (2000) Neurosci Lett , vol.288 , pp. 175-178
    • Frahm, C.1    Engel, D.2    Piechotta, A.3    Heinemann, U.4    Draguhn, A.5
  • 18
    • 0034871560 scopus 로고    scopus 로고
    • Tiagabine in clinical practice
    • Genton P, Guerrini R and Perucca E. Tiagabine in clinical practice. Epilepsia 42, Suppl 3: 42-45, 2001.
    • (2001) Epilepsia , vol.42 , Issue.SUPPL. 3 , pp. 42-45
    • Genton, P.1    Guerrini, R.2    Perucca, E.3
  • 20
    • 0030732152 scopus 로고    scopus 로고
    • Synaptic communication among hippocampal interneurons: Properties of spontaneous IPSCs in morphologically identified cells
    • Hájos N and Mody I. Synaptic communication among hippocampal interneurons: properties of spontaneous IPSCs in morphologically identified cells. J Neurosci 17: 8427-8442, 1997.
    • (1997) J Neurosci , vol.17 , pp. 8427-8442
    • Hájos, N.1    Mody, I.2
  • 22
    • 0027401230 scopus 로고
    • Local and diffuse synaptic actions of GABA in the hippocampus
    • Isaacson JS, Solis JM, and Nicoll RA. Local and diffuse synaptic actions of GABA in the hippocampus. Neuron 10: 165-175, 1993.
    • (1993) Neuron , vol.10 , pp. 165-175
    • Isaacson, J.S.1    Solis, J.M.2    Nicoll, R.A.3
  • 28
    • 0037440094 scopus 로고    scopus 로고
    • B receptor modulation of excitatory and inhibitory synaptic transmission onto rat CA3 hippocampal intemeurons
    • B receptor modulation of excitatory and inhibitory synaptic transmission onto rat CA3 hippocampal intemeurons. J Physiol 546: 439-453, 2003.
    • (2003) J Physiol , vol.546 , pp. 439-453
    • Lei, S.1    McBain, C.J.2
  • 30
    • 0344881975 scopus 로고    scopus 로고
    • A IPSC magnitude but not saturation of fast inhibitory efficacy in rat neocortical pyramidal cells
    • A IPSC magnitude but not saturation of fast inhibitory efficacy in rat neocortical pyramidal cells. Synapse 28: 91-102, 1998.
    • (1998) Synapse , vol.28 , pp. 91-102
    • Ling, D.S.1    Benardo, L.S.2
  • 31
    • 0033681141 scopus 로고    scopus 로고
    • Presynaptic calcium stores underlie large-amplitude miniature IPSCs and spontaneous calcium transients
    • Llano I, Gonzalez J, Caputo C, Lai FA, Blayney LM, Tan YP, and Marty A. Presynaptic calcium stores underlie large-amplitude miniature IPSCs and spontaneous calcium transients. Nat Neurosci 3: 1256-1265, 2000.
    • (2000) Nat Neurosci , vol.3 , pp. 1256-1265
    • Llano, I.1    Gonzalez, J.2    Caputo, C.3    Lai, F.A.4    Blayney, L.M.5    Tan, Y.P.6    Marty, A.7
  • 32
    • 0032456284 scopus 로고    scopus 로고
    • Pharmacological characterization of nicotinic receptor-stimulated GABA release from mouse brain synaptosomes
    • Lu Y, Grady S, Marks MJ, Picciotto M, Changeux JP, and Collins AC. Pharmacological characterization of nicotinic receptor-stimulated GABA release from mouse brain synaptosomes. J Pharmacol Exp Ther 287: 648-657, 1998.
    • (1998) J Pharmacol Exp Ther , vol.287 , pp. 648-657
    • Lu, Y.1    Grady, S.2    Marks, M.J.3    Picciotto, M.4    Changeux, J.P.5    Collins, A.C.6
  • 33
    • 0039357820 scopus 로고    scopus 로고
    • + channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons
    • + channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons. Neuron 19: 687-695, 1997.
    • (1997) Neuron , vol.19 , pp. 687-695
    • Luscher, C.1    Jan, L.Y.2    Stoffel, M.3    Malenka, R.C.4    Nicoll, R.A.5
  • 34
    • 0033135549 scopus 로고    scopus 로고
    • Glutamatergic synapses onto hippocampal interneurons: Precision timing without lasting plasticity
    • McBain CJ, Freund TF, and Mody I. Glutamatergic synapses onto hippocampal interneurons: precision timing without lasting plasticity. Trends Neurosci 22: 228-235, 1999.
    • (1999) Trends Neurosci , vol.22 , pp. 228-235
    • McBain, C.J.1    Freund, T.F.2    Mody, I.3
  • 35
    • 0028849688 scopus 로고
    • GAT-1, a high-affinity GABA plasma membrane transporter, is localized to neurons and astroglia in the cerebral cortex
    • Minelli A, Brecha NC, Karschin C, DeBiasi S, and Conti F. GAT-1, a high-affinity GABA plasma membrane transporter, is localized to neurons and astroglia in the cerebral cortex. J Neurosci 15: 7734-7746, 1995.
    • (1995) J Neurosci , vol.15 , pp. 7734-7746
    • Minelli, A.1    Brecha, N.C.2    Karschin, C.3    DeBiasi, S.4    Conti, F.5
  • 36
    • 0034554837 scopus 로고    scopus 로고
    • GABA spillover from single inhibitory axons suppresses low-frequency excitatory transmission at the cerebellar glomerulus
    • Mitchell SJ and Silver RA. GABA spillover from single inhibitory axons suppresses low-frequency excitatory transmission at the cerebellar glomerulus. J Neurosci 20: 8651-8658, 2000.
    • (2000) J Neurosci , vol.20 , pp. 8651-8658
    • Mitchell, S.J.1    Silver, R.A.2
  • 37
    • 0034764735 scopus 로고    scopus 로고
    • A receptors responsible for tonic and phasic conductances
    • A receptors responsible for tonic and phasic conductances. Neurochem Res 26: 907-913, 2001.
    • (2001) Neurochem Res , vol.26 , pp. 907-913
    • Mody, I.1
  • 38
    • 0021219280 scopus 로고
    • Rapid preparation of synaptosomes from mammalian brain using nontoxic isoosmotic gradient material (Percoll)
    • Nagy A and Delgado-Escueta AV. Rapid preparation of synaptosomes from mammalian brain using nontoxic isoosmotic gradient material (Percoll). J Neurochem 43: 1114-1123, 1984.
    • (1984) J Neurochem , vol.43 , pp. 1114-1123
    • Nagy, A.1    Delgado-Escueta, A.V.2
  • 39
    • 0036097970 scopus 로고    scopus 로고
    • Selective modulation of tonic and phasic inhibitions in dentate gyrus granule cells
    • Nusser Z and Mody I. Selective modulation of tonic and phasic inhibitions in dentate gyrus granule cells. J Neurophysiol 87: 2624-2628, 2002.
    • (2002) J Neurophysiol , vol.87 , pp. 2624-2628
    • Nusser, Z.1    Mody, I.2
  • 41
    • 0026697352 scopus 로고
    • A receptor-mediated spontaneous inhibitory postsynaptic currents in hippocampal neurons
    • A receptor-mediated spontaneous inhibitory postsynaptic currents in hippocampal neurons. Neuroscience 49: 13-32, 1992.
    • (1992) Neuroscience , vol.49 , pp. 13-32
    • Otis, T.S.1    Mody, I.2
  • 43
    • 0034900683 scopus 로고    scopus 로고
    • Paradoxical reduction of synaptic inhibition by vigabatrin
    • Overstreet LS and Westbrook GL. Paradoxical reduction of synaptic inhibition by vigabatrin. J Neurophysiol 86: 596-603, 2001.
    • (2001) J Neurophysiol , vol.86 , pp. 596-603
    • Overstreet, L.S.1    Westbrook, G.L.2
  • 44
    • 0037388630 scopus 로고    scopus 로고
    • Synapse density regulates independence at unitary inhibitory synapses
    • Overstreet LS and Westbrook GL. Synapse density regulates independence at unitary inhibitory synapses. J Neurosci 23: 2618-2626, 2003.
    • (2003) J Neurosci , vol.23 , pp. 2618-2626
    • Overstreet, L.S.1    Westbrook, G.L.2
  • 46
    • 0027992775 scopus 로고
    • Factors contributing to the decay of the stimulus-evoked IPSC in rat hippocampal CA1 neurons
    • Roepstorff A and Lambert JDC. Factors contributing to the decay of the stimulus-evoked IPSC in rat hippocampal CA1 neurons. J Neurophysiol 72: 2911-2926, 1994.
    • (1994) J Neurophysiol , vol.72 , pp. 2911-2926
    • Roepstorff, A.1    Lambert, J.D.C.2
  • 48
    • 0037408550 scopus 로고    scopus 로고
    • GABA uptake regulates cortical excitability via cell type-specific tonic inhibition
    • Semyanov A, Walker MC, and Kullmann DM. GABA uptake regulates cortical excitability via cell type-specific tonic inhibition. Nat Neurosci 6: 484-490, 2003.
    • (2003) Nat Neurosci , vol.6 , pp. 484-490
    • Semyanov, A.1    Walker, M.C.2    Kullmann, D.M.3
  • 50
    • 0036250012 scopus 로고    scopus 로고
    • Serotonin reuptake inhibition: An update on current research strategies
    • Spinks D and Spinks G. Serotonin reuptake inhibition: an update on current research strategies. Curr Med Chem 9: 799-810, 2002.
    • (2002) Curr Med Chem , vol.9 , pp. 799-810
    • Spinks, D.1    Spinks, G.2
  • 51
    • 0037095726 scopus 로고    scopus 로고
    • A conductances in hippocampal neurons
    • A conductances in hippocampal neurons. J Neurosci 22: RC223, 2002.
    • (2002) J Neurosci , vol.22
    • Stell, B.M.1    Mody, I.2
  • 52
    • 0026771403 scopus 로고
    • Effects of the GABA uptake inhibitor tiagabine on inhibitory synaptic potentials in rat hippocampal slice cultures
    • Thompson SM and Gähwiler BH. Effects of the GABA uptake inhibitor tiagabine on inhibitory synaptic potentials in rat hippocampal slice cultures. J Neurophysiol 67: 1698-1701, 1992.
    • (1992) J Neurophysiol , vol.67 , pp. 1698-1701
    • Thompson, S.M.1    Gähwiler, B.H.2
  • 53
    • 0029066723 scopus 로고
    • 3H]tiagabine binding to sections from mice brain
    • 3H]tiagabine binding to sections from mice brain. Epilepsy Res 21: 79-88, 1995.
    • (1995) Epilepsy Res , vol.21 , pp. 79-88
    • Thomsen, C.1    Suzdak, P.D.2
  • 55
    • 0037083577 scopus 로고    scopus 로고
    • Differential desensitization of responses mediated by presynaptic and postsynaptic A1 adenosine receptors
    • Wetherington JP and Lambert NA. Differential desensitization of responses mediated by presynaptic and postsynaptic A1 adenosine receptors. J Neurosci 22: 1248-1255, 2002.
    • (2002) J Neurosci , vol.22 , pp. 1248-1255
    • Wetherington, J.P.1    Lambert, N.A.2
  • 56
    • 0037389053 scopus 로고    scopus 로고
    • Vigabatrin induces tonic inhibition via GABA transporter reversal without increasing vesicular GABA release
    • Wu Y, Wang W, and Richerson GB. Vigabatrin induces tonic inhibition via GABA transporter reversal without increasing vesicular GABA release. J Neurophysiol 89: 2021-2034, 2003.
    • (2003) J Neurophysiol , vol.89 , pp. 2021-2034
    • Wu, Y.1    Wang, W.2    Richerson, G.B.3
  • 57
    • 0025953030 scopus 로고
    • The modulation of rat hippocampal synaptic conductances by baclofen and gamma-aminobutyric acid
    • Yoon KW and Rothman SM. The modulation of rat hippocampal synaptic conductances by baclofen and gamma-aminobutyric acid. J Physiol 442: 377-390, 1991.
    • (1991) J Physiol , vol.442 , pp. 377-390
    • Yoon, K.W.1    Rothman, S.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.