메뉴 건너뛰기




Volumn 68, Issue 3, 2014, Pages 475-487

Implementation of the nutrition and health claim regulation - The case of antioxidants

Author keywords

Antioxidants; EFSA; European Commission; Food law; Functional ingredients; Multifactorial; Nutrition research; Oxidative stress; Scientific substantiation

Indexed keywords

ANTIOXIDANT;

EID: 84895182807     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2014.01.014     Document Type: Article
Times cited : (42)

References (98)
  • 1
    • 21444440754 scopus 로고    scopus 로고
    • PASSCLAIM, process for the assessment of scientific support for claims on foods
    • Aggett P.J., et al. PASSCLAIM, process for the assessment of scientific support for claims on foods. Eur. J. Nutr. 2005, 44:i1-i2.
    • (2005) Eur. J. Nutr. , vol.44
    • Aggett, P.J.1
  • 2
  • 3
    • 77956625356 scopus 로고    scopus 로고
    • Evidence-based criteria in the nutritional context
    • Blumberg J., et al. Evidence-based criteria in the nutritional context. Nutr. Rev. 2010, 68:478-484.
    • (2010) Nutr. Rev. , vol.68 , pp. 478-484
    • Blumberg, J.1
  • 4
    • 11044227119 scopus 로고    scopus 로고
    • EFSA: Excellence, integrity and openness
    • Inaugural Meeting of the Management Board of the European Food Safety Authority Brussels
    • Byrne, D., 2002. EFSA: Excellence, integrity and openness. Inaugural Meeting of the Management Board of the European Food Safety Authority Brussels.
    • (2002)
    • Byrne, D.1
  • 5
    • 84895146929 scopus 로고    scopus 로고
    • A review on antioxidants, prooxidants and related controversy: natural and synthetic compounds, screening and analysis methodologies and future perspectives
    • Carocho M., Ferreira I.C.F.R. A review on antioxidants, prooxidants and related controversy: natural and synthetic compounds, screening and analysis methodologies and future perspectives. Food Chem. Toxicol 2012.
    • (2012) Food Chem. Toxicol
    • Carocho, M.1    Ferreira, I.C.F.R.2
  • 6
    • 84895101410 scopus 로고    scopus 로고
    • Codex Alimentarius Commission (CAC). Revised Codex Standard for Honey
    • Codex Alimentarius Commission (CAC), 2001. Revised Codex Standard for Honey. <>. http://www.codexalimentarius.org/standards/list-of-standards/en/?provide=standards%26orderField=fullReference%26sort=asc%26num1=CODEX.
    • (2001)
  • 7
    • 54349124273 scopus 로고    scopus 로고
    • Nrf2-induced antioxidant protection: a promising target to counteract ROS-mediated damage in neurodegenerative disease?
    • de Vries H.E., et al. Nrf2-induced antioxidant protection: a promising target to counteract ROS-mediated damage in neurodegenerative disease?. Free Radic. Biol. Med. 2008, 45:1375-1383.
    • (2008) Free Radic. Biol. Med. , vol.45 , pp. 1375-1383
    • de Vries, H.E.1
  • 8
    • 83855161653 scopus 로고    scopus 로고
    • Perceived relevance and foods with health-related claims
    • Dean M., et al. Perceived relevance and foods with health-related claims. Food Qual. Prefer. 2012, 24:129-135.
    • (2012) Food Qual. Prefer. , vol.24 , pp. 129-135
    • Dean, M.1
  • 9
    • 0033035294 scopus 로고    scopus 로고
    • Scientific concepts in functional foods in Europe: consensus document
    • Diplock A.T., et al. Scientific concepts in functional foods in Europe: consensus document. Br. J. Nutr. 1999, 81.
    • (1999) Br. J. Nutr. , vol.81
    • Diplock, A.T.1
  • 10
    • 36649036960 scopus 로고    scopus 로고
    • Nutrigenomic approaches for benefit-risk analysis of foods and food components: defining markers of health
    • Elliott R., et al. Nutrigenomic approaches for benefit-risk analysis of foods and food components: defining markers of health. Br. J. Nutr. 2007, 98:1095-1100.
    • (2007) Br. J. Nutr. , vol.98 , pp. 1095-1100
    • Elliott, R.1
  • 11
    • 84895125352 scopus 로고    scopus 로고
    • External Evaluation of EFSA - Final Report
    • Ernst, Young, 2012. External Evaluation of EFSA - Final Report. <>. http://www.efsa.europa.eu/en/keydocs/docs/efsafinalreport.pdf.
    • (2012)
    • Ernst, Y.1
  • 12
    • 84895154906 scopus 로고    scopus 로고
    • Europe Press Releases. Questions and Answers on Health and Nutrition Claims
    • Europe Press Releases, 2006. Questions and Answers on Health and Nutrition Claims. <>. http://europa.eu/rapid/press-release_MEMO-06-200_en.htm?locale=en.
    • (2006)
  • 13
    • 84895078965 scopus 로고    scopus 로고
    • European Commission, The general principles of food law in the European Union - Commission green paper. COM (1997)
    • European Commission, 1997. The general principles of food law in the European Union - Commission green paper. COM (1997), 176.
    • (1997) , pp. 176
  • 14
    • 84895083236 scopus 로고    scopus 로고
    • European Commission, 2000. White paper on food safety. COM
    • European Commission, 2000. White paper on food safety. COM (1999), 719.
    • (1999) , pp. 719
  • 15
    • 84895158295 scopus 로고    scopus 로고
    • European Commission, Discussion paper on nutrition claims and functional claims
    • European Commission, 2001. Discussion paper on nutrition claims and functional claims.
    • (2001)
  • 16
    • 84895085405 scopus 로고    scopus 로고
    • European Commission, Proposal for a regulation of the European Parliament and of the Council on nutrition and health claims made on foods
    • European Commission, 2003a. Proposal for a regulation of the European Parliament and of the Council on nutrition and health claims made on foods. <>. http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=COM:2003:0424:FIN:EN:PDF.
    • (2003)
  • 17
    • 84895095273 scopus 로고    scopus 로고
    • European Commission, Proposal for a regulation of the European Parliament and of the Council on nutrition and health claims made on foods. Brussels
    • European Commission, 2003b. Proposal for a regulation of the European Parliament and of the Council on nutrition and health claims made on foods. Brussels <>. http://europa.%20eu.%20int/eur-lex/en/com/pdf/2003/com2003_0424en01.%20pdf.
    • (2003)
  • 18
    • 84895147529 scopus 로고    scopus 로고
    • European Commission, Terms of Reference. OJ L. 12.
    • European Commission, 2007. Terms of Reference. OJ L. 12.
    • (2007)
  • 19
    • 84895109691 scopus 로고    scopus 로고
    • European Commission, Commission Regulation (EC) No 353/2008 of 18 April 2008 establishing implementing rules for applications for authorisation of health claims as provided for in Article 15 of Regulation (EC) No 1924/2006 of the European Parliament and of the Council. OJ L.
    • European Commission, 2008. Commission Regulation (EC) No 353/2008 of 18 April 2008 establishing implementing rules for applications for authorisation of health claims as provided for in Article 15 of Regulation (EC) No 1924/2006 of the European Parliament and of the Council. OJ L. 109.
    • (2008) , vol.109
  • 20
    • 84895080961 scopus 로고    scopus 로고
    • European Commission, Commission Regulation (EU) No 365/2010 of 28 April 2010 amending Regulation (EC) No 2073/2005 on microbiological criteria for foodstuffs as regards Enterobacteriaceae in pasteurised milk and other pasteurised liquid dairy products and Listeria monocytogenes in food grade salt. OJ L.
    • European Commission, 2010. Commission Regulation (EU) No 365/2010 of 28 April 2010 amending Regulation (EC) No 2073/2005 on microbiological criteria for foodstuffs as regards Enterobacteriaceae in pasteurised milk and other pasteurised liquid dairy products and Listeria monocytogenes in food grade salt. OJ L. 107, 9.
    • (2010) , vol.107 , pp. 9
  • 21
    • 84895197323 scopus 로고    scopus 로고
    • European Commission, Commission Regulation (EU) No 432/2012 of 16 May 2012 establishing a list of permitted health claims made on foods, other than those referring to the reduction of disease risk and to children's development and health. OJ L.
    • European Commission, 2012a. Commission Regulation (EU) No 432/2012 of 16 May 2012 establishing a list of permitted health claims made on foods, other than those referring to the reduction of disease risk and to children's development and health. OJ L. 55, 1-40.
    • (2012) , vol.55 , pp. 1-40
  • 22
    • 84895160529 scopus 로고    scopus 로고
    • European Commission, EU Register on nutrition and health claims
    • European Commission, 2012b. EU Register on nutrition and health claims. <>. http://ec.europa.eu/nuhclaims/?event=search%26CFID=335086%26CFTOKEN=bb484f431b227bd1-79366084-B936-26BA-A093EC372F6F1B31%26jsessionid=9312c835f5666f4342c4403366511152f434TR.
    • (2012)
  • 23
    • 84895105727 scopus 로고    scopus 로고
    • European Commission, Commission Regulation (EU) No 536/2013 of 11 June 2013 amending Regulation (EU) No 432/2012 establishing a list of permitted health claims made on foods other than those referring to the reduction of disease risk and to children's development and health. OJ L
    • European Commission, 2013. Commission Regulation (EU) No 536/2013 of 11 June 2013 amending Regulation (EU) No 432/2012 establishing a list of permitted health claims made on foods other than those referring to the reduction of disease risk and to children's development and health. OJ L 160.
    • (2013) , vol.160
  • 24
    • 84895167019 scopus 로고    scopus 로고
    • European Food Information Council, Functional Foods
    • European Food Information Council, Functional Foods. <>. http://www.eufic.org/article/en/expid/basics-functional-foods/.
  • 25
    • 84895123938 scopus 로고    scopus 로고
    • European Food Safety Authority. About the NDA Panel and the Nutrition Unit
    • European Food Safety Authority, 2013. About the NDA Panel and the Nutrition Unit. <>. http://www.efsa.europa.eu/en/nda/aboutnda.htm.
    • (2013)
  • 26
    • 84895164217 scopus 로고    scopus 로고
    • European Food Safety Authority, "General function" health claims under Article 13.
    • European Food Safety Authority, 2013 "General function" health claims under Article 13. <>. http://www.efsa.europa.eu/en/topics/topic/article13.htm.
    • (2013)
  • 27
    • 84895131129 scopus 로고    scopus 로고
    • European Food Safety Authority. "New function" health claims under Article 13.5
    • European Food Safety Authority, 2013. "New function" health claims under Article 13.5. <>. http://www.efsa.europa.eu/en/topics/topic/article13-5.htm.
    • (2013)
  • 28
    • 84895120027 scopus 로고    scopus 로고
    • European Food Safety Authority. Claims on disease risk reduction and child development or health under Article 14
    • European Food Safety Authority, 2013. Claims on disease risk reduction and child development or health under Article 14. <>. http://www.efsa.europa.eu/en/topics/topic/article14.htm.
    • (2013)
  • 29
    • 84895120339 scopus 로고    scopus 로고
    • European Food Safety Authority. EFSA: What we do
    • European Food Safety Authority, 2013. EFSA: What we do. <>. http://www.efsa.europa.eu/en/aboutefsa/efsawhat.htm.
    • (2013)
  • 30
    • 84895155810 scopus 로고    scopus 로고
    • European Food Safety Authority. EFSA: Risk Assessment
    • European Food Safety Authority, 2013. EFSA: Risk Assessment. <>. http://www.efsa.europa.eu/en/efsawhat/riskassessment.htm.
    • (2013)
  • 31
    • 84895081660 scopus 로고    scopus 로고
    • European Food Safety Authority. EFSA corporate documents
    • European Food Safety Authority, 2013. EFSA corporate documents. <>. http://www.efsa.europa.eu/en/aboutefsa/keydocs.htm.
    • (2013)
  • 32
    • 84895115754 scopus 로고    scopus 로고
    • European Food Safety Authority. EFSA: FAQ on nutrition and health claims
    • European Food Safety Authority, 2013. EFSA: FAQ on nutrition and health claims. <>. http://www.efsa.europa.eu/en/faqs/faqnutrition.htm?wtrl=01.
    • (2013)
  • 33
    • 84895110393 scopus 로고    scopus 로고
    • European Food Safety Authority. Criteria for the initial screening of Article 13(3) health claims of Regulation (EC) No 1924/2006
    • European Food Safety Authority, 2008. Criteria for the initial screening of Article 13(3) health claims of Regulation (EC) No 1924/2006. <>. http://www.efsa.europa.eu/en/ndaclaims13/docs/ndaart13torax01.pdf.
    • (2008)
  • 34
    • 84895141140 scopus 로고    scopus 로고
    • European Food Safety Authority. EFSA's Modus operandi for Article 13(3) Health Claims of Regulation (EC) No 1924/2006
    • European Food Safety Authority, 2010. EFSA's Modus operandi for Article 13(3) Health Claims of Regulation (EC) No 1924/2006. <>. http://www.efsa.europa.eu/en/ndaclaims13/docs/art13modusoperandi.pdf.
    • (2010)
  • 35
    • 84895086446 scopus 로고    scopus 로고
    • European Food Safety Authority. Petition Nutrition and Health Claims
    • European Food Safety Authority, 2012. Petition Nutrition and Health Claims. <>. http://ec.europa.eu/food/food/labellingnutrition/claims/docs/petition_nutrition_health_claims_230712_en.pdf.
    • (2012)
  • 36
    • 84895092385 scopus 로고    scopus 로고
    • European Parliament and the Council, Regulation (EC) No 178/2002 of the European Parliament and of the Council of 28 January 2002 laying down the general principles and requirements of food law, establishing the European Food Safety Authority and laying down procedures in matters of food safety. OJ L.
    • European Parliament and the Council, 2002. Regulation (EC) No 178/2002 of the European Parliament and of the Council of 28 January 2002 laying down the general principles and requirements of food law, establishing the European Food Safety Authority and laying down procedures in matters of food safety. OJ L. 31, 1-24.
    • (2002) , vol.31 , pp. 1-24
  • 37
    • 84895118026 scopus 로고    scopus 로고
    • European Parliament and the Council, Regulation (EC) No 1924/2006 of the European Parliament and of the council of 20 December 2006 on nutrition and health claims made on foods. OJ L.
    • European Parliament and the Council, 2006. Regulation (EC) No 1924/2006 of the European Parliament and of the council of 20 December 2006 on nutrition and health claims made on foods. OJ L. 404, 9-25.
    • (2006) , vol.404 , pp. 9-25
  • 38
    • 84895114064 scopus 로고    scopus 로고
    • European Parliament and the Council, Regulation (EC) No 1334/2008 of the European Parliament and of the Council of 16 December 2008 on flavourings and certain food ingredients with flavouring properties for use in and on foods and amending Council Regulation (EEC) No 1601/91, Regulations (EC) No 2232/96 and (EC) No 110/2008 and Directive 2000/13/EC. OJ L.
    • European Parliament and the Council, 2008. Regulation (EC) No 1334/2008 of the European Parliament and of the Council of 16 December 2008 on flavourings and certain food ingredients with flavouring properties for use in and on foods and amending Council Regulation (EEC) No 1601/91, Regulations (EC) No 2232/96 and (EC) No 110/2008 and Directive 2000/13/EC. OJ L. 354.
    • (2008) , vol.354
  • 39
    • 84895123567 scopus 로고    scopus 로고
    • European Parliament and the Council, Regulation (EU) No 1169/2011 of the European Parliament and of the Council of 25 October 2011 on the provision of food information to consumers, amending Regulations (EC) No 1924/2006 and (EC) No 1925/2006 of the European Parliament and of the Council, and repealing Commission Directive 87/250/EEC, Council Directive 90/496/EEC, Commission Directive 1999/10/EC, Directive 2000/13/EC of the European Parliament and of the Council, Commission Directives 2002/67/EC and 2008/5/EC and Commission Regulation (EC) No 608/2004 Text with EEA relevance. OJ L.
    • European Parliament and the Council, 2011. Regulation (EU) No 1169/2011 of the European Parliament and of the Council of 25 October 2011 on the provision of food information to consumers, amending Regulations (EC) No 1924/2006 and (EC) No 1925/2006 of the European Parliament and of the Council, and repealing Commission Directive 87/250/EEC, Council Directive 90/496/EEC, Commission Directive 1999/10/EC, Directive 2000/13/EC of the European Parliament and of the Council, Commission Directives 2002/67/EC and 2008/5/EC and Commission Regulation (EC) No 608/2004 Text with EEA relevance. OJ L. 304.
    • (2011) , vol.304
  • 40
    • 84856257307 scopus 로고    scopus 로고
    • Symposium 2: nutrition and health claims: help or hindrance Scientific substantiation of health claims in the EU
    • Flynn A. Symposium 2: nutrition and health claims: help or hindrance Scientific substantiation of health claims in the EU. Proc. Nutr. Soc. 2012, 71:120-126.
    • (2012) Proc. Nutr. Soc. , vol.71 , pp. 120-126
    • Flynn, A.1
  • 41
    • 84892369382 scopus 로고    scopus 로고
    • How do nutritional antioxidants really work: nucleophilic tone and para-hormesis versus free radical scavenging in vivo
    • Forman H.J., et al. How do nutritional antioxidants really work: nucleophilic tone and para-hormesis versus free radical scavenging in vivo. Free Radic. Biol. Med. 2014, 66:24-35.
    • (2014) Free Radic. Biol. Med. , vol.66 , pp. 24-35
    • Forman, H.J.1
  • 42
    • 34948888880 scopus 로고    scopus 로고
    • Dietary flavones and flavonoles are inhibitors of poly(ADP-ribose)polymerase-1 in pulmonary epithelial cells
    • Geraets L., et al. Dietary flavones and flavonoles are inhibitors of poly(ADP-ribose)polymerase-1 in pulmonary epithelial cells. J. Nutr. 2007, 137:2190-2195.
    • (2007) J. Nutr. , vol.137 , pp. 2190-2195
    • Geraets, L.1
  • 43
    • 80855162412 scopus 로고    scopus 로고
    • Nutrition & health claims in the European Union: a regulatory overview
    • Gilsenan M. Nutrition & health claims in the European Union: a regulatory overview. Trends Food Sci. Technol. 2011, 22:536-542.
    • (2011) Trends Food Sci. Technol. , vol.22 , pp. 536-542
    • Gilsenan, M.1
  • 44
    • 0029824431 scopus 로고    scopus 로고
    • Antioxidants in human health and disease
    • Halliwell B. Antioxidants in human health and disease. Annu. Rev. Nutr. 1996, 16:33-50.
    • (1996) Annu. Rev. Nutr. , vol.16 , pp. 33-50
    • Halliwell, B.1
  • 45
    • 36749010860 scopus 로고    scopus 로고
    • Biochemistry of oxidative stress
    • Halliwell B. Biochemistry of oxidative stress. Biochem. Soc. Trans. 2007, 35:1147-1150.
    • (2007) Biochem. Soc. Trans. , vol.35 , pp. 1147-1150
    • Halliwell, B.1
  • 46
    • 79952442409 scopus 로고    scopus 로고
    • Free radicals and antioxidants - quo vadis?
    • Halliwell B. Free radicals and antioxidants - quo vadis?. Trends Pharmacol. Sci. 2011, 32:125-130.
    • (2011) Trends Pharmacol. Sci. , vol.32 , pp. 125-130
    • Halliwell, B.1
  • 47
    • 84895149559 scopus 로고    scopus 로고
    • Nutrition and health - transforming research traditions
    • Hanekamp J.C., et al. Nutrition and health - transforming research traditions. Crit. Rev. Food Sci. Nutr. 2013.
    • (2013) Crit. Rev. Food Sci. Nutr.
    • Hanekamp, J.C.1
  • 48
    • 84855693993 scopus 로고    scopus 로고
    • The anti-inflammatory effect of lycopene complements the antioxidant action of ascorbic acid and α-tocopherol
    • Hazewindus M., et al. The anti-inflammatory effect of lycopene complements the antioxidant action of ascorbic acid and α-tocopherol. Food Chem. 2012, 132:954-958.
    • (2012) Food Chem. , vol.132 , pp. 954-958
    • Hazewindus, M.1
  • 49
    • 84895195520 scopus 로고    scopus 로고
    • Health and Consumer Protection Directorate General. Food law from farm to table - Creating a European Food Authority
    • Health and Consumer Protection Directorate General, 2000. Food law from farm to table - Creating a European Food Authority. <>. http://ec.europa.eu/dgs/health_consumer/library/press/press82_en.html.
    • (2000)
  • 50
    • 51049085594 scopus 로고    scopus 로고
    • Nutrients, endpoints, and the problem of proof
    • Heaney R.P. Nutrients, endpoints, and the problem of proof. J. Nutr. 2008, 138:1591-1595.
    • (2008) J. Nutr. , vol.138 , pp. 1591-1595
    • Heaney, R.P.1
  • 51
    • 0036774226 scopus 로고    scopus 로고
    • Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships
    • Heim K.E., et al. Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships. J. Nutr. Biochem. 2002, 13:572-584.
    • (2002) J. Nutr. Biochem. , vol.13 , pp. 572-584
    • Heim, K.E.1
  • 52
    • 84895120739 scopus 로고    scopus 로고
    • Scientific method and the regulation of health and nutritional claims by the European Food Safety Authority
    • Hoad D. Scientific method and the regulation of health and nutritional claims by the European Food Safety Authority. Bull Sci. Technol. Soc. 2011, 31:123-133.
    • (2011) Bull Sci. Technol. Soc. , vol.31 , pp. 123-133
    • Hoad, D.1
  • 53
    • 0041783046 scopus 로고    scopus 로고
    • Transcending reductionism in nutrition research
    • Hoffmann I. Transcending reductionism in nutrition research. Am. J. Clin. Nutr. 2003, 78:514S-516S.
    • (2003) Am. J. Clin. Nutr. , vol.78
    • Hoffmann, I.1
  • 54
    • 79960938952 scopus 로고    scopus 로고
    • How should we define health?
    • Huber M., et al. How should we define health?. BMJ 2011, 343.
    • (2011) BMJ , vol.343
    • Huber, M.1
  • 55
    • 0042284031 scopus 로고    scopus 로고
    • Nutrients, foods, and dietary patterns as exposures in research: a framework for food synergy
    • Jacobs D.R., Steffen L.M. Nutrients, foods, and dietary patterns as exposures in research: a framework for food synergy. Am. J. Clin. Nutr. 2003, 78:508S-513S.
    • (2003) Am. J. Clin. Nutr. , vol.78
    • Jacobs, D.R.1    Steffen, L.M.2
  • 56
    • 38449090657 scopus 로고    scopus 로고
    • Food, not nutrients, is the fundamental unit in nutrition
    • Jacobs D.R., Tapsell L.C. Food, not nutrients, is the fundamental unit in nutrition. Nutr. Rev. 2007, 65:439-450.
    • (2007) Nutr. Rev. , vol.65 , pp. 439-450
    • Jacobs, D.R.1    Tapsell, L.C.2
  • 57
    • 33746211196 scopus 로고    scopus 로고
    • OMICS-driven biomarker discovery in nutrition and health
    • Kussmann M., et al. OMICS-driven biomarker discovery in nutrition and health. J. Biotechnol. 2006, 124:758-787.
    • (2006) J. Biotechnol. , vol.124 , pp. 758-787
    • Kussmann, M.1
  • 59
    • 84895094444 scopus 로고    scopus 로고
    • Cholesterol limits lose their lustre
    • Revised guidelines for heart health are set to move away from target-based approach
    • Ledford, H., 2013. Cholesterol limits lose their lustre. Revised guidelines for heart health are set to move away from target-based approach. <>. http://www.nature.com/news/cholesterol-limits-lose-their-lustre-1.12509?WT.ec_id=NATURE-20130228.
    • (2013)
    • Ledford, H.1
  • 60
    • 38049138602 scopus 로고    scopus 로고
    • Europeanising advisory expertise: the role of 'independent, objective and transparent' scientific advice in agri-biotech regulation
    • Levidow L., Carr S. Europeanising advisory expertise: the role of 'independent, objective and transparent' scientific advice in agri-biotech regulation. Environ. Plann. C Gov. Policy 2007, 26:880-895.
    • (2007) Environ. Plann. C Gov. Policy , vol.26 , pp. 880-895
    • Levidow, L.1    Carr, S.2
  • 61
    • 84862059860 scopus 로고    scopus 로고
    • Phytochemical antioxidants modulate Mammalian cellular epigenome: implications in health and disease
    • Malireddy S., et al. Phytochemical antioxidants modulate Mammalian cellular epigenome: implications in health and disease. Antioxid. Redox Signal. 2012, 17:327-339.
    • (2012) Antioxid. Redox Signal. , vol.17 , pp. 327-339
    • Malireddy, S.1
  • 62
    • 25144482448 scopus 로고    scopus 로고
    • Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymes
    • Masella R., et al. Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymes. J. Nutr. Biochem. 2005, 16:577-586.
    • (2005) J. Nutr. Biochem. , vol.16 , pp. 577-586
    • Masella, R.1
  • 63
    • 84870547013 scopus 로고    scopus 로고
    • Functional foods: regulation and innovations in the EU
    • Moors E.H. Functional foods: regulation and innovations in the EU. Innovation 2012, 25:424-440.
    • (2012) Innovation , vol.25 , pp. 424-440
    • Moors, E.H.1
  • 64
    • 85042117590 scopus 로고    scopus 로고
    • NDA Panel EFSA, Scientific Opinion on the substantiation of health claims related to copper and protection of DNA, proteins and lipids from oxidative damage (ID 263, 1726), function of the immune system (ID 264), maintenance of connective tissues (ID 265, 271, 1722), energy-yielding metabolism (ID 266), function of the nervous system (ID 267), maintenance of skin and hair pigmentation (ID 268, 1724), iron transport (ID 269, 270, 1727), cholesterol metabolism (ID 369), and glucose metabolism (ID 369) pursuant to Article 13(1) of Regulation (EC) No 1924/2006
    • NDA Panel EFSA, 2009a. Scientific Opinion on the substantiation of health claims related to copper and protection of DNA, proteins and lipids from oxidative damage (ID 263, 1726), function of the immune system (ID 264), maintenance of connective tissues (ID 265, 271, 1722), energy-yielding metabolism (ID 266), function of the nervous system (ID 267), maintenance of skin and hair pigmentation (ID 268, 1724), iron transport (ID 269, 270, 1727), cholesterol metabolism (ID 369), and glucose metabolism (ID 369) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA J. 7, 1211.
    • (2009) EFSA J. , vol.7 , pp. 1211
  • 65
    • 84895197680 scopus 로고    scopus 로고
    • NDA Panel EFSA, Scientific Opinion on Water-soluble tomato concentrate (WSTC I and II) and platelet aggregation Scientific substantiation of a health claim related to water-soluble tomato concentrate (WSTC I and II) and platelet aggregation pursuant to Article 13(5) of Regulation (EC) No 1924/2006.
    • NDA Panel EFSA, 2009b. Scientific Opinion on Water-soluble tomato concentrate (WSTC I and II) and platelet aggregation Scientific substantiation of a health claim related to water-soluble tomato concentrate (WSTC I and II) and platelet aggregation pursuant to Article 13(5) of Regulation (EC) No 1924/2006. EFSA J. 1101.
    • (2009) EFSA J. , pp. 1101
  • 66
    • 85078372018 scopus 로고    scopus 로고
    • NDA Panel EFSA, Scientific Opinion on the modification of the authorisation of a health claim related to water-soluble tomato concentrate and helps to maintain a healthy blood flow and benefits circulation pursuant to Article 13(5) of Regulation (EC) No 1924/2006 following a request in accordance with Article 19 of the Regulation (EC) No 1924/2006.
    • NDA Panel EFSA, 2010a. Scientific Opinion on the modification of the authorisation of a health claim related to water-soluble tomato concentrate and helps to maintain a healthy blood flow and benefits circulation pursuant to Article 13(5) of Regulation (EC) No 1924/2006 following a request in accordance with Article 19 of the Regulation (EC) No 1924/2006. EFSA J. 8, 1689.
    • (2010) EFSA J. , vol.8 , pp. 1689
  • 67
    • 84895168767 scopus 로고    scopus 로고
    • NDA Panel EFSA, Scientific Opinion on the substantiation of health claims related to various food(s)/food constituent(s) and protection of cells from premature ageing (ID 1668, 1917, 2515, 2527, 2530, 2575, 2580, 2591, 2620, 3178, 3179, 3180, 3181, 4329, 4415), antioxidant activity, antioxidant content and antioxidant properties (ID 857, 1306, 2515, 2527, 2530, 2575, 2580, 2591, 2629, 2728, 4327, 4365, 4380, 4390, 4394, 4455, 4464, 4507, 4694, 4705), protection of DNA, proteins and lipids from oxidative damage (ID 1196, 1211, 1216, 1306, 1312, 1440, 1441, 1666, 1668, 1692, 1900, 1914, 1948, 2023, 2158, 2517, 2522, 2527, 2575, 2591, 2620, 2637, 2639, 2663, 2860, 3079, 3276, 3564, 3818, 4324, 4329, 4351, 4397, 4416, 4424, 4507, 4527, 4528, 4542, 4611, 4629, 4659) and bioavailability of anthocyanins in black currants (ID 4220) pursuant to Article 13(1) of Regulation (EC) No 1924/2006.
    • NDA Panel EFSA, 2010b. Scientific Opinion on the substantiation of health claims related to various food(s)/food constituent(s) and protection of cells from premature ageing (ID 1668, 1917, 2515, 2527, 2530, 2575, 2580, 2591, 2620, 3178, 3179, 3180, 3181, 4329, 4415), antioxidant activity, antioxidant content and antioxidant properties (ID 857, 1306, 2515, 2527, 2530, 2575, 2580, 2591, 2629, 2728, 4327, 4365, 4380, 4390, 4394, 4455, 4464, 4507, 4694, 4705), protection of DNA, proteins and lipids from oxidative damage (ID 1196, 1211, 1216, 1306, 1312, 1440, 1441, 1666, 1668, 1692, 1900, 1914, 1948, 2023, 2158, 2517, 2522, 2527, 2575, 2591, 2620, 2637, 2639, 2663, 2860, 3079, 3276, 3564, 3818, 4324, 4329, 4351, 4397, 4416, 4424, 4507, 4527, 4528, 4542, 4611, 4629, 4659) and bioavailability of anthocyanins in black currants (ID 4220) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA J. 8, 1752.
    • (2010) EFSA J. , vol.8 , pp. 1752
  • 68
    • 85060513757 scopus 로고    scopus 로고
    • NDA Panel EFSA, Scientific Opinion on the substantiation of health claims related to various food(s)/food constituent(s) and protection of cells from premature aging, antioxidant activity, antioxidant content and antioxidant properties, and protection of DNA, proteins and lipids from oxidative damage pursuant to Article 13(1) of Regulation (EC) No 1924/2006.
    • NDA Panel EFSA, 2010c. Scientific Opinion on the substantiation of health claims related to various food(s)/food constituent(s) and protection of cells from premature aging, antioxidant activity, antioxidant content and antioxidant properties, and protection of DNA, proteins and lipids from oxidative damage pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA J. 8, 1489.
    • (2010) EFSA J. , vol.8 , pp. 1489
  • 69
    • 84906803115 scopus 로고    scopus 로고
    • NDA Panel EFSA, General guidance for stakeholders on the evaluation of Article 13.1, 13.5 and 14 health claims.
    • NDA Panel EFSA, 2011a. General guidance for stakeholders on the evaluation of Article 13.1, 13.5 and 14 health claims. EFSA J. 9, 2135.
    • (2011) EFSA J. , vol.9 , pp. 2135
  • 70
    • 85078379344 scopus 로고    scopus 로고
    • NDA Panel EFSA, Scientific Opinion on the substantiation of health claims related to beta-carotene and protection of DNA, proteins and lipids from oxidative damage (ID 19, 197, 1262, 1460), protection of the skin from UV-induced (including photo-oxidative) damage (ID 178, 197, 1263, 1461, 1968, 2320) and maintenance of the normal function of the immune system (ID 200, 1462) pursuant to Article 13(1) of Regulation (EC) No 1924/2006.
    • NDA Panel EFSA, 2011b. Scientific Opinion on the substantiation of health claims related to beta-carotene and protection of DNA, proteins and lipids from oxidative damage (ID 19, 197, 1262, 1460), protection of the skin from UV-induced (including photo-oxidative) damage (ID 178, 197, 1263, 1461, 1968, 2320) and maintenance of the normal function of the immune system (ID 200, 1462) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA J. 9, 2021.
    • (2011) EFSA J. , vol.9 , pp. 2021
  • 71
    • 85042092402 scopus 로고    scopus 로고
    • NDA Panel EFSA, Scientific Opinion on the substantiation of health claims related to lutein and protection of DNA, proteins and lipids from oxidative damage (ID 3427), protection of the skin from UV-induced (including photo-oxidative) damage (ID 1605, 1779) and maintenance of normal vision (ID 1779, 2080) pursuant to Article 13(1) of regulation (EC) No 1924/2006.
    • NDA Panel EFSA, 2011c. Scientific Opinion on the substantiation of health claims related to lutein and protection of DNA, proteins and lipids from oxidative damage (ID 3427), protection of the skin from UV-induced (including photo-oxidative) damage (ID 1605, 1779) and maintenance of normal vision (ID 1779, 2080) pursuant to Article 13(1) of regulation (EC) No 1924/2006. EFSA J. 9, 2030.
    • (2011) EFSA J. , vol.9 , pp. 2030
  • 72
    • 84855530450 scopus 로고    scopus 로고
    • NDA Panel EFSA, Scientific Opinion on the substantiation of health claims related to polyphenols in olive and protection of LDL particles from oxidative damage (ID 1333, 1638, 1639, 1696, 2865), maintenance of normal blood HDL-cholesterol concentrations (ID 1639), maintenance of normal blood pressure (ID 3781), "anti-inflammatory properties" (ID 1882), "contributes to the upper respiratory tract health" (ID 3468), "can help to maintain a normal function of gastrointestinal tract" (3779), and "contributes to body defences against external agents" (ID 3467) pursuant to Article 13(1) of Regulation (EC) No 1924/2006.
    • NDA Panel EFSA, 2011d. Scientific Opinion on the substantiation of health claims related to polyphenols in olive and protection of LDL particles from oxidative damage (ID 1333, 1638, 1639, 1696, 2865), maintenance of normal blood HDL-cholesterol concentrations (ID 1639), maintenance of normal blood pressure (ID 3781), "anti-inflammatory properties" (ID 1882), "contributes to the upper respiratory tract health" (ID 3468), "can help to maintain a normal function of gastrointestinal tract" (3779), and "contributes to body defences against external agents" (ID 3467) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA J. 9, 2033.
    • (2011) EFSA J. , vol.9 , pp. 2033
  • 73
    • 84954535431 scopus 로고    scopus 로고
    • NDA Panel EFSA, Scientific Opinion on the substantiation of health claims related to: dairy products (ID 1140, 1141, 1191), raw or processed food products of animal origin, plus bread and panification products (ID 1193, 1194), herbal yeast plasmolysate (ID 1815, 1816), apple polyphenols (ID 2713), rye flour (ID 1266), tomato juice (ID 1202), whey protein and alphalactalbumin (ID 424, 430, 432, 725, 1433), "brocco shoots", "broccoli sprout powder" and "Brassica oleracea var. italica (broccoli)" (ID 1362, 1481, 2844, 2845), honey (ID 1159, 1160, 1318, 4678, 4679), and Cucurbita pepo L. (pumpkin) seeds and seed extracts (ID 2029, 2365) pursuant to Article 13(1) of Regulation (EC) No 1924/2006.
    • NDA Panel EFSA, 2011e. Scientific Opinion on the substantiation of health claims related to: dairy products (ID 1140, 1141, 1191), raw or processed food products of animal origin, plus bread and panification products (ID 1193, 1194), herbal yeast plasmolysate (ID 1815, 1816), apple polyphenols (ID 2713), rye flour (ID 1266), tomato juice (ID 1202), whey protein and alphalactalbumin (ID 424, 430, 432, 725, 1433), "brocco shoots", "broccoli sprout powder" and "Brassica oleracea var. italica (broccoli)" (ID 1362, 1481, 2844, 2845), honey (ID 1159, 1160, 1318, 4678, 4679), and Cucurbita pepo L. (pumpkin) seeds and seed extracts (ID 2029, 2365) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA J. 9, 2243.
    • (2011) EFSA J. , vol.9 , pp. 2243
  • 74
    • 85072407666 scopus 로고    scopus 로고
    • NDA Panel EFSA, Scientific Opinion on the substantiation of health claims related to: flavonoids and ascorbic acid in fruit juices, including berry juices (ID 1186); flavonoids from citrus (ID 1471); flavonoids from Citrus paradisi Macfad. (ID 3324, 3325); flavonoids (ID 1470, 1693, 1920); flavonoids in cranberry juice (ID 1804); carotenoids (ID 1496, 1621, 1622, 1796); polyphenols (ID 1636, 1637, 1640, 1641, 1642, 1643); rye bread (ID 1179); protein hydrolysate (ID 1646); carbohydrates with a low/reduced glycaemic load (ID 476, 477, 478, 479, 602) and carbohydrates which induce a low/reduced glycaemic response (ID 727, 1122, 1171); alfalfa (ID 1361, 2585, 2722, 2793); caffeinated carbohydrate-containing energy drinks (ID 1272); and soups (ID 1132, 1133) pursuant to Article 13(1) of Regulation (EC) No 1924/2006.
    • NDA Panel EFSA, 2011f. Scientific Opinion on the substantiation of health claims related to: flavonoids and ascorbic acid in fruit juices, including berry juices (ID 1186); flavonoids from citrus (ID 1471); flavonoids from Citrus paradisi Macfad. (ID 3324, 3325); flavonoids (ID 1470, 1693, 1920); flavonoids in cranberry juice (ID 1804); carotenoids (ID 1496, 1621, 1622, 1796); polyphenols (ID 1636, 1637, 1640, 1641, 1642, 1643); rye bread (ID 1179); protein hydrolysate (ID 1646); carbohydrates with a low/reduced glycaemic load (ID 476, 477, 478, 479, 602) and carbohydrates which induce a low/reduced glycaemic response (ID 727, 1122, 1171); alfalfa (ID 1361, 2585, 2722, 2793); caffeinated carbohydrate-containing energy drinks (ID 1272); and soups (ID 1132, 1133) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA J. 9, 2082.
    • (2011) EFSA J. , vol.9 , pp. 2082
  • 75
    • 85042393928 scopus 로고    scopus 로고
    • NDA Panel EFSA, Scientific Opinion on the substantiation of a health claim related to 3g/day plant sterols/stanols and lowering blood LDL-cholesterol and reduced risk of (coronary) heart disease pursuant to Article 19 of Regulation (EC) No 1924/2006.
    • NDA Panel EFSA, 2012a. Scientific Opinion on the substantiation of a health claim related to 3g/day plant sterols/stanols and lowering blood LDL-cholesterol and reduced risk of (coronary) heart disease pursuant to Article 19 of Regulation (EC) No 1924/2006. EFSA J. 10, 2693.
    • (2012) EFSA J. , vol.10 , pp. 2693
  • 76
    • 85058775121 scopus 로고    scopus 로고
    • NDA Panel EFSA, Scientific Opinion on the substantiation of a health claim related to cocoa flavanols and maintenance of normal endothelium-dependent vasodilation pursuant to Article 13(5) of Regulation (EC) No 1924/2006.
    • NDA Panel EFSA, 2012b. Scientific Opinion on the substantiation of a health claim related to cocoa flavanols and maintenance of normal endothelium-dependent vasodilation pursuant to Article 13(5) of Regulation (EC) No 1924/2006. EFSA J. 10, 2809.
    • (2012) EFSA J. , vol.10 , pp. 2809
  • 77
    • 3142570440 scopus 로고    scopus 로고
    • The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress
    • Nguyen T., et al. The pathways and molecular mechanisms regulating Nrf2 activation in response to chemical stress. Free Radic. Biol. Med. 2004, 37:433-441.
    • (2004) Free Radic. Biol. Med. , vol.37 , pp. 433-441
    • Nguyen, T.1
  • 78
    • 84864069455 scopus 로고    scopus 로고
    • Food health claims - What consumers understand
    • Nocella G., Kennedy O. Food health claims - What consumers understand. Food Policy 2012, 37:571-580.
    • (2012) Food Policy , vol.37 , pp. 571-580
    • Nocella, G.1    Kennedy, O.2
  • 79
    • 0036708902 scopus 로고    scopus 로고
    • Antioxidants and oxidants regulated signal transduction pathways
    • Owuor E.D., Kong A.-N.T. Antioxidants and oxidants regulated signal transduction pathways. Biochem. Pharmacol. 2002, 64:765-770.
    • (2002) Biochem. Pharmacol. , vol.64 , pp. 765-770
    • Owuor, E.D.1    Kong, A.-N.T.2
  • 80
    • 84857789767 scopus 로고    scopus 로고
    • Plasma metabolomics and proteomics profiling after a postprandial challenge reveal subtle diet effects on human metabolic status
    • Pellis L., et al. Plasma metabolomics and proteomics profiling after a postprandial challenge reveal subtle diet effects on human metabolic status. Metabolomics 2012, 8:347-359.
    • (2012) Metabolomics , vol.8 , pp. 347-359
    • Pellis, L.1
  • 82
    • 84880215208 scopus 로고    scopus 로고
    • The role of Nrf2 in the attenuation of cardiovascular disease
    • Reuland D.J., et al. The role of Nrf2 in the attenuation of cardiovascular disease. Exerc. Sport Sci. Rev 2013.
    • (2013) Exerc. Sport Sci. Rev
    • Reuland, D.J.1
  • 83
    • 78651082295 scopus 로고    scopus 로고
    • Nutrition ecology - a concept for systemic nutrition research and integrative problem solving
    • Schneider K., Hoffmann I. Nutrition ecology - a concept for systemic nutrition research and integrative problem solving. Ecol. Food Nutr. 2011, 50:1-17.
    • (2011) Ecol. Food Nutr. , vol.50 , pp. 1-17
    • Schneider, K.1    Hoffmann, I.2
  • 84
    • 40949112830 scopus 로고    scopus 로고
    • The fifth anniversary of the European Food Safety Authority (EFSA): Mission, organization, functioning and main results
    • Silano M., Silano V. The fifth anniversary of the European Food Safety Authority (EFSA): Mission, organization, functioning and main results. Fitoterapia 2008, 79:149-160.
    • (2008) Fitoterapia , vol.79 , pp. 149-160
    • Silano, M.1    Silano, V.2
  • 85
    • 70350411859 scopus 로고    scopus 로고
    • From mutual recognition to mutual scientific opinion? Constitutional framework for risk analysis in EU food safety law
    • Szajkowska A. From mutual recognition to mutual scientific opinion? Constitutional framework for risk analysis in EU food safety law. Food Policy 2009, 34:529-538.
    • (2009) Food Policy , vol.34 , pp. 529-538
    • Szajkowska, A.1
  • 86
    • 84895140276 scopus 로고    scopus 로고
    • The role of nutrition and health claims in consumers' perception. Creating educational paths to resolve information asymmetries caused by promotion and marketing activities regarding foodstuffs
    • Tarabella A., Burchi B. The role of nutrition and health claims in consumers' perception. Creating educational paths to resolve information asymmetries caused by promotion and marketing activities regarding foodstuffs. Procedia Soc. Behav. Sci. 2012, 46:2173-2177.
    • (2012) Procedia Soc. Behav. Sci. , vol.46 , pp. 2173-2177
    • Tarabella, A.1    Burchi, B.2
  • 87
    • 79961020609 scopus 로고    scopus 로고
    • Food matrix impact on macronutrients nutritional properties
    • Turgeon S.L., Rioux L.-E. Food matrix impact on macronutrients nutritional properties. Food Hydrocoll. 2011, 25:1915-1924.
    • (2011) Food Hydrocoll. , vol.25 , pp. 1915-1924
    • Turgeon, S.L.1    Rioux, L.-E.2
  • 91
    • 84873201118 scopus 로고    scopus 로고
    • System of food law in the European Union
    • van der Meulen B.M. System of food law in the European Union. Deakin Law Rev. 2009, 14:305.
    • (2009) Deakin Law Rev. , vol.14 , pp. 305
    • van der Meulen, B.M.1
  • 92
    • 68149164116 scopus 로고    scopus 로고
    • Challenging homeostasis to define biomarkers for nutrition related health
    • van Ommen B., et al. Challenging homeostasis to define biomarkers for nutrition related health. Mol. Nutr. Food Res. 2009, 53:795-804.
    • (2009) Mol. Nutr. Food Res. , vol.53 , pp. 795-804
    • van Ommen, B.1
  • 93
    • 0036812118 scopus 로고    scopus 로고
    • Nutrigenomics: exploiting systems biology in the nutrition and health arena
    • Van Ommen B., Stierum R. Nutrigenomics: exploiting systems biology in the nutrition and health arena. Curr. Opin. Biotechnol. 2002, 13:517-521.
    • (2002) Curr. Opin. Biotechnol. , vol.13 , pp. 517-521
    • Van Ommen, B.1    Stierum, R.2
  • 94
    • 75649140897 scopus 로고    scopus 로고
    • Consumer understanding and nutritional communication: key issues in the context of the new EU legislation
    • van Trijp H.C. Consumer understanding and nutritional communication: key issues in the context of the new EU legislation. Eur. J. Nutr. 2009, 48:41-48.
    • (2009) Eur. J. Nutr. , vol.48 , pp. 41-48
    • van Trijp, H.C.1
  • 95
    • 77956180679 scopus 로고    scopus 로고
    • Status of nutrition and health claims in Europe
    • Verhagen H., et al. Status of nutrition and health claims in Europe. Arch. Biochem. Biophys. 2010, 501:6-15.
    • (2010) Arch. Biochem. Biophys. , vol.501 , pp. 6-15
    • Verhagen, H.1
  • 96
    • 77956395196 scopus 로고    scopus 로고
    • Oxidative stress and vascular function: implications for pharmacologic treatments
    • Weseler A.R., Bast A. Oxidative stress and vascular function: implications for pharmacologic treatments. Curr. Hypertens. Rep. 2010, 12:154-161.
    • (2010) Curr. Hypertens. Rep. , vol.12 , pp. 154-161
    • Weseler, A.R.1    Bast, A.2
  • 97
    • 84866378550 scopus 로고    scopus 로고
    • Pleiotropic-acting nutrients require integrative investigational approaches: the example of flavonoids
    • Weseler A.R., Bast A. Pleiotropic-acting nutrients require integrative investigational approaches: the example of flavonoids. J. Agric. Food Chem. 2012, 60:8941-8946.
    • (2012) J. Agric. Food Chem. , vol.60 , pp. 8941-8946
    • Weseler, A.R.1    Bast, A.2
  • 98
    • 84895189701 scopus 로고    scopus 로고
    • World Health Organization. Constitution of the World Health Organization
    • World Health Organization, 2006. Constitution of the World Health Organization. <>. http://www.who.int/governance/eb/who_constitution_en.pdf.
    • (2006)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.