-
1
-
-
34250359779
-
Emerging role of Nrf2 in protecting against hepatic and gastrointestinal disease
-
Aleksunes LM, Manautou JE. Emerging role of Nrf2 in protecting against hepatic and gastrointestinal disease. Toxicol. Pathol. 2007; 35:459-73.
-
(2007)
Toxicol. Pathol.
, vol.35
, pp. 459-473
-
-
Aleksunes, L.M.1
Manautou, J.E.2
-
2
-
-
33847378451
-
Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: Systematic review and meta-analysis
-
Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: Systematic review and meta-analysis. JAMA 2007; 297: 842-57.
-
(2007)
JAMA
, vol.297
, pp. 842-857
-
-
Bjelakovic, G.1
Nikolova, D.2
Gluud, L.L.3
Simonetti, R.G.4
Gluud, C.5
-
3
-
-
58849110632
-
The Nrf2/ARE pathway as a potential therapeutic target in neurodegenerative disease
-
Calkins MJ, Johnson DA, Townsend JA, et al. The Nrf2/ARE pathway as a potential therapeutic target in neurodegenerative disease. Antioxid. Redox. Signal 2009; 11:497-508.
-
(2009)
Antioxid. Redox. Signal
, vol.11
, pp. 497-508
-
-
Calkins, M.J.1
Johnson, D.A.2
Townsend, J.A.3
-
4
-
-
84867694835
-
Does Nrf2 contribute to p53-mediated control of cell survival and death? Antioxid
-
Chen W, Jiang T, Wang H, Tao S, Lau A, Fang D, Zhang DD. Does Nrf2 contribute to p53-mediated control of cell survival and death? Antioxid. Redox. Signal. 2012; 17:1670-5.
-
(2012)
Redox. Signal.
, vol.17
, pp. 1670-1675
-
-
Chen, W.1
Jiang, T.2
Wang, H.3
Tao, S.4
Lau, A.5
Fang, D.6
Zhang, D.D.7
-
5
-
-
34848858001
-
Biomechanical forces in atherosclerosis-resistant vascular regions regulate endothelial redox balance via phosphoinositol 3-kinase/AktY dependent activation of Nrf2
-
Dai G, Vaughn S, Zhang Y, Wang ET, Garcia-Cardena G, Gimbrone MA Jr. Biomechanical forces in atherosclerosis-resistant vascular regions regulate endothelial redox balance via phosphoinositol 3-kinase/AktY dependent activation of Nrf2. Circ. Res. 2007; 101:723-33.
-
(2007)
Circ. Res.
, vol.101
, pp. 723-733
-
-
Dai, G.1
Vaughn, S.2
Zhang, Y.3
Wang, E.T.4
Garcia-Cardena, G.5
Gimbrone Jr., M.A.6
-
6
-
-
0037015035
-
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
-
Dinkova-Kostova AT, Holtzclaw WD, Cole RN, et al. Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants. Proc. Natl. Acad. Sci. U. S. A. 2002; 99:11908-13.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 11908-13
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Cole, R.N.3
-
7
-
-
84862278246
-
Phytochemical activation of Nrf2 protects human coronary artery endothelial cells against an oxidative challenge
-
2012 [Article ID 132931]: 9 pp
-
Donovan EL, McCord JM, Reuland DJ, Miller BF, Hamilton KL. Phytochemical activation of Nrf2 protects human coronary artery endothelial cells against an oxidative challenge. Oxid. Med. Cell Longev. 2012; 2012 [Article ID 132931]:9 p.p.
-
(2012)
Oxid. Med. Cell Longev.
-
-
Donovan, E.L.1
McCord, J.M.2
Reuland, D.J.3
Miller, B.F.4
Hamilton, K.L.5
-
8
-
-
79960269808
-
Exercise-induced cardiac preconditioning: How exercise protects your achy-breaky heart
-
Frasier CR, Moore RL, Brown DA. Exercise-induced cardiac preconditioning: How exercise protects your achy-breaky heart. J. Appl. Physiol. 2011; 111:905-15.
-
(2011)
J. Appl. Physiol.
, vol.111
, pp. 905-915
-
-
Frasier, C.R.1
Moore, R.L.2
Brown, D.A.3
-
9
-
-
37849021505
-
Moderate exercise is an antioxidant: Upregulation of antioxidant genes by training
-
Gomez-Cabrera MC, Domenech E, Vina J. Moderate exercise is an antioxidant: Upregulation of antioxidant genes by training. Free Radic. Biol. Med. 2008; 44:126-31.
-
(2008)
Free Radic. Biol. Med.
, vol.44
, pp. 126-131
-
-
Gomez-Cabrera, M.C.1
Domenech, E.2
Vina, J.3
-
11
-
-
84866645959
-
Impaired transcriptional activity of Nrf2 in age-related myocardial oxidative stress is reversible by moderate exercise training
-
Gounder SS, Kannan S, Devadoss D, et al. Impaired transcriptional activity of Nrf2 in age-related myocardial oxidative stress is reversible by moderate exercise training. PLoS One 2012; 7:e45697.
-
(2012)
PLoS One
, vol.7
-
-
Gounder, S.S.1
Kannan, S.2
Devadoss, D.3
-
12
-
-
0242349764
-
Oxidative stress and cardiovascular injury: Part II: Animal and human studies
-
Griendling KK, FitzGerald GA. Oxidative stress and cardiovascular injury: Part II: Animal and human studies. Circulation 2003; 108:2034-40.
-
(2003)
Circulation
, vol.108
, pp. 2034-2040
-
-
Griendling, K.K.1
FitzGerald, G.A.2
-
13
-
-
34548463341
-
Antioxidants and cardioprotection
-
Hamilton KL. Antioxidants and cardioprotection. Med. Sci. Sports Exerc. 2007; 39:1544-53.
-
(2007)
Med. Sci. Sports Exerc.
, vol.39
, pp. 1544-1553
-
-
Hamilton, K.L.1
-
14
-
-
81855204961
-
Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation
-
Hybertson BM, Gao B, Bose SK, McCord JM. Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation. Mol. Aspects Med. 2011; 32:234-46.
-
(2011)
Mol. Aspects Med.
, vol.32
, pp. 234-246
-
-
Hybertson, B.M.1
Gao, B.2
Bose, S.K.3
McCord, J.M.4
-
15
-
-
77955608828
-
Different susceptibility to the Parkinson"s toxin MPTP in mice lacking the redox master regulator Nrf2 or its target gene heme oxygenase-1
-
Innamorato NG, Jazwa A, Rojo AI, et al. Different susceptibility to the Parkinson"s toxin MPTP in mice lacking the redox master regulator Nrf2 or its target gene heme oxygenase-1. PLoS One 2010; 5:e11838.
-
(2010)
PLoS One
, vol.5
-
-
Innamorato, N.G.1
Jazwa, A.2
Rojo, A.I.3
-
16
-
-
12444257799
-
Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles
-
Itoh K, Wakabayashi N, Katoh Y, Ishii T, Connor OT, Yamamoto M. Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles. Genes Cells 2003; 8:379-91.
-
(2003)
Genes Cells
, vol.8
, pp. 379-391
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Connor, O.T.5
Yamamoto, M.6
-
17
-
-
77954599053
-
P62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription
-
Jain A, Lamark T, Sjottem E, et al. p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription. J. Biol. Chem. 2010; 285:22576-91.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 22576-91
-
-
Jain, A.1
Lamark, T.2
Sjottem, E.3
-
18
-
-
33744962865
-
Redefining oxidative stress
-
Jones DP. Redefining oxidative stress. Antioxid. Redox. Signal 2006; 8: 1865-79.
-
(2006)
Antioxid. Redox. Signal
, vol.8
, pp. 1865-1879
-
-
Jones, D.P.1
-
19
-
-
0036240610
-
Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: Role of antioxidant response element-like sequences in the nrf2 promoter
-
Kwak MK, Itoh K, Yamamoto M, Kensler TW. Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: Role of antioxidant response element-like sequences in the nrf2 promoter. Mol. Cell Biol. 2002; 22:2883-92.
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 2883-2892
-
-
Kwak, M.K.1
Itoh, K.2
Yamamoto, M.3
Kensler, T.W.4
-
20
-
-
0037424262
-
Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway Identification of novel gene clusters for cell survival
-
Kwak MK, Wakabayashi N, Itoh K, Motohashi H, Yamamoto M, Kensler TW. Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival. J. Biol. Chem. 2003; 278:8135-45.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8135-8145
-
-
Kwak, M.K.1
Wakabayashi, N.2
Itoh, K.3
Motohashi, H.4
Yamamoto, M.5
Kensler, T.W.6
-
22
-
-
77950352188
-
An internal ribosomal entry site mediates redox-sensitive translation of Nrf2
-
Li W, Thakor N, Xu EY, et al. An internal ribosomal entry site mediates redox-sensitive translation of Nrf2. Nucleic Acids Res. 2010; 38:778-88.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 778-788
-
-
Li, W.1
Thakor, N.2
Xu, E.Y.3
-
23
-
-
42649130014
-
PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria
-
Lo SC, Hannink M. PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria. Exp. Cell Res. 2008; 314:1789-803.
-
(2008)
Exp. Cell Res.
, vol.314
, pp. 1789-803
-
-
Lo, S.C.1
Hannink, M.2
-
25
-
-
84855451533
-
Acute exercise stress activates Nrf2/ARE signaling and promotes antioxidant mechanisms in the myocardium
-
Muthusamy VR, Kannan S, Sadhaasivam K, et al. Acute exercise stress activates Nrf2/ARE signaling and promotes antioxidant mechanisms in the myocardium. Free Radic. Biol. Med. 2012; 52:366-76.
-
(2012)
Free Radic. Biol. Med.
, vol.52
, pp. 366-376
-
-
Muthusamy, V.R.1
Kannan, S.2
Sadhaasivam, K.3
-
26
-
-
30344461640
-
The induction of human superoxide dismutase and catalase in vivo: A fundamentally new approach to antioxidant therapy
-
Nelson SK, Bose SK, Grunwald GK, Myhill P, McCord JM. The induction of human superoxide dismutase and catalase in vivo: A fundamentally new approach to antioxidant therapy. Free Radic. Biol. Med. 2006; 40:341-7.
-
(2006)
Free Radic. Biol. Med.
, vol.40
, pp. 341-347
-
-
Nelson, S.K.1
Bose, S.K.2
Grunwald, G.K.3
Myhill, P.4
McCord, J.M.5
-
27
-
-
58149328569
-
Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1
-
Piantadosi CA, Carraway MS, Babiker A, Suliman HB. Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1. Circ. Res. 2008; 103:1232-40.
-
(2008)
Circ. Res.
, vol.103
, pp. 1232-1240
-
-
Piantadosi, C.A.1
Carraway, M.S.2
Babiker, A.3
Suliman, H.B.4
-
28
-
-
84858972249
-
Nrf2-dependent induction of proteasome and Pa28alphabeta regulator are required for adaptation to oxidative stress
-
Pickering AM, Linder RA, Zhang H, Forman HJ, Davies KJ. Nrf2-dependent induction of proteasome and Pa28alphabeta regulator are required for adaptation to oxidative stress. J. Biol. Chem. 2012; 287: 10021-31.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 10021-31
-
-
Pickering, A.M.1
Linder, R.A.2
Zhang, H.3
Forman, H.J.4
Davies, K.J.5
-
29
-
-
34748904643
-
Translational control of nrf2 protein in activation of antioxidant response by oxidants
-
Purdom-Dickinson SE, Sheveleva EV, Sun H, Chen QM. Translational control of nrf2 protein in activation of antioxidant response by oxidants. Mol. Pharmacol. 2007; 72:1074-81.
-
(2007)
Mol. Pharmacol.
, vol.72
, pp. 1074-1081
-
-
Purdom-Dickinson, S.E.1
Sheveleva, E.V.2
Sun, H.3
Chen, Q.M.4
-
30
-
-
36248963187
-
Exercise-induced cardioprotection: An overview of a unique form of preconditioning
-
Quindry JC, Hamilton KL. Exercise-induced cardioprotection: An overview of a unique form of preconditioning. Curr. Cardiol. Rev. 2007; 3:255-63.
-
(2007)
Curr. Cardiol. Rev.
, vol.3
, pp. 255-263
-
-
Quindry, J.C.1
Hamilton, K.L.2
-
31
-
-
84872159740
-
Upregulation of phase II enzymes through phytochemical activation of Nrf2 protects cardiomyocytes against oxidant stress
-
Reuland DJ, Khademi S, Castle CJ, Irwin DC, McCord JM, Miller BF, Hamilton KL. Upregulation of phase II enzymes through phytochemical activation of Nrf2 protects cardiomyocytes against oxidant stress. Free Radic. Biol. Med. 2012; 56:102-11.
-
(2012)
Free Radic. Biol. Med.
, vol.56
, pp. 102-111
-
-
Reuland, D.J.1
Khademi, S.2
Castle, C.J.3
Irwin, D.C.4
McCord, J.M.5
Miller, B.F.6
Hamilton, K.L.7
-
32
-
-
79951662200
-
Nuclear factorYerythroid 2Yrelated factor 2 as a chemopreventive target in colorectal cancer
-
Saw CL, Kong AN. Nuclear factorYerythroid 2Yrelated factor 2 as a chemopreventive target in colorectal cancer. Expert Opin. Ther. Targets 2011; 15:281-95.
-
(2011)
Expert Opin. Ther. Targets
, vol.15
, pp. 281-295
-
-
Saw, C.L.1
Kong, A.N.2
-
33
-
-
1542723493
-
Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione syn
-
thesis, which is reversible with lipoic acid
-
Suh JH, Shenvi SV, Dixon BM, Liu H, Jaiswal AK, Liu RM, Hagen TM. Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid. Proc. Natl. Acad. Sci. U. S. A. 2004; 101:3381-6.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 3381-3386
-
-
Suh, J.H.1
Shenvi, S.V.2
Dixon, B.M.3
Liu, H.4
Jaiswal, A.K.5
Liu, R.M.6
Hagen, T.M.7
-
34
-
-
56249106571
-
Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals
-
Surh YJ, Kundu JK, Na HK. Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals. Planta Med. 2008; 74:1526-39.
-
(2008)
Planta Med.
, vol.74
, pp. 1526-1539
-
-
Surh, Y.J.1
Kundu, J.K.2
Na, H.K.3
-
35
-
-
58149086400
-
Synergistic induction of heme oxygenase-1 by the components of the antioxidant supplement Protandim
-
Velmurugan K, Alam J, McCord JM, Pugazhenthi S. Synergistic induction of heme oxygenase-1 by the components of the antioxidant supplement Protandim. Free Radic. Biol. Med. 2009; 46:430-40.
-
(2009)
Free Radic. Biol. Med.
, vol.46
, pp. 430-440
-
-
Velmurugan, K.1
Alam, J.2
McCord, J.M.3
Pugazhenthi, S.4
-
37
-
-
0033532699
-
Exercise provides direct biphasic cardioprotection via manganese superoxide dismutase activation
-
Yamashita N, Hoshida S, Otsu K, Asahi M, Kuzuya T, Hori M. Exercise provides direct biphasic cardioprotection via manganese superoxide dismutase activation. J. Exp. Med. 1999; 189:1699-1706.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1699-1706
-
-
Yamashita, N.1
Hoshida, S.2
Otsu, K.3
Asahi, M.4
Kuzuya, T.5
Hori, M.6
-
38
-
-
84870396636
-
Participation of protein kinase C in the activation of Nrf2 signaling by ischemic preconditioning in the isolated rabbit heart
-
Zhang X, Xiao Z, Yao J, Zhao G, Fa X, Niu J. Participation of protein kinase C in the activation of Nrf2 signaling by ischemic preconditioning in the isolated rabbit heart. Mol. Cell Biochem. 2013; 372:169-79.
-
(2013)
Mol. Cell Biochem.
, vol.372
, pp. 169-179
-
-
Zhang, X.1
Xiao, Z.2
Yao, J.3
Zhao, G.4
Fa, X.5
Niu, J.6
-
39
-
-
51449117002
-
Nuclear factor E2Yrelated factor 2Ydependent myocardiac cytoprotection against oxidative and electrophilic stress
-
Zhu H, Jia Z, Misra BR, et al. Nuclear factor E2Yrelated factor 2Ydependent myocardiac cytoprotection against oxidative and electrophilic stress. Cardiovasc. Toxicol. 2008; 8:71-85. Station
-
(2008)
Cardiovasc. Toxicol.
, vol.8
, pp. 71-85
-
-
Zhu, H.1
Jia, Z.2
Misra, B.R.3
|