-
1
-
-
48349128407
-
Should colorectal cancer screening start at the same age in European countries? Contributions from descriptive epidemiology
-
Brenner H, Hoffmeister M, Haug U. Should colorectal cancer screening start at the same age in European countries? Contributions from descriptive epidemiology. Br J Cancer 2008; 99:532-535.
-
(2008)
Br J Cancer
, vol.99
, pp. 532-535
-
-
Brenner, H.1
Hoffmeister, M.2
Haug, U.3
-
2
-
-
0036788829
-
The genetics of colorectal cancer
-
Calvert PM, Frucht H. The genetics of colorectal cancer. Ann Intern Med 2002; 137:603-612.
-
(2002)
Ann Intern Med
, vol.137
, pp. 603-612
-
-
Calvert, P.M.1
Frucht, H.2
-
3
-
-
17844368327
-
The MAPK signalling pathways and colorectal cancer
-
Fang JY, Richardson BC. The MAPK signalling pathways and colorectal cancer. Lancet Oncol 2005; 6:322-327.
-
(2005)
Lancet Oncol
, vol.6
, pp. 322-327
-
-
Fang, J.Y.1
Richardson, B.C.2
-
4
-
-
0032928614
-
Mitogen-activated protein kinase: Conservation of a three-kinase module from yeast to human
-
Widmann C, Gibson S, Jarpe MB, Johnson GL. Mitogen-activated protein kinase: Conservation of a three-kinase module from yeast to human. Physiol Rev 1999; 79:143-180.
-
(1999)
Physiol Rev
, vol.79
, pp. 143-180
-
-
Widmann, C.1
Gibson, S.2
Jarpe, M.B.3
Johnson, G.L.4
-
5
-
-
0037213006
-
Computational modeling of the EGF-receptor system: A paradigm for systems biology
-
Wiley HS, Shvartsman SY, Lauffenburger DA. Computational modeling of the EGF-receptor system: A paradigm for systems biology. Trends Cell Biol 2003; 13:43-50.
-
(2003)
Trends Cell Biol
, vol.13
, pp. 43-50
-
-
Wiley, H.S.1
Shvartsman, S.Y.2
Lauffenburger, D.A.3
-
6
-
-
29144435996
-
Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway
-
Orton RJ, Sturm OE, Vyshemirsky V, Calder M, Gilbert DR, Kolch W. Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway. Biochem J 2005; 392:249-261.
-
(2005)
Biochem J
, vol.392
, pp. 249-261
-
-
Orton, R.J.1
Sturm, O.E.2
Vyshemirsky, V.3
Calder, M.4
Gilbert, D.R.5
Kolch, W.6
-
7
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF gene in human cancer. Nature 2002; 417:949-954.
-
(2002)
Nature
, vol.417
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
-
8
-
-
0033590636
-
Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors
-
Hoshino R, Chatani Y, Yamori T, et al. Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors. Oncogene 1999; 18:813-822.
-
(1999)
Oncogene
, vol.18
, pp. 813-822
-
-
Hoshino, R.1
Chatani, Y.2
Yamori, T.3
-
9
-
-
80053353907
-
Trs65p, a subunit of the Ypt1p GEF TRAPPII, interacts with the Arf1p exchange factor Gea2p to facilitate COPI-mediated vesicle traffic
-
Chen S, Cai H, Park SK, Menon S, Jackson CL, Ferro-Novick S. Trs65p, a subunit of the Ypt1p GEF TRAPPII, interacts with the Arf1p exchange factor Gea2p to facilitate COPI-mediated vesicle traffic. Mol Biol Cell 2011; 22:3634-3644.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 3634-3644
-
-
Chen, S.1
Cai, H.2
Park, S.K.3
Menon, S.4
Jackson, C.L.5
Ferro-Novick, S.6
-
10
-
-
84878116698
-
The SMS domain of Trs23p is responsible for the in vitro appearance of the TRAPP I complex in Saccharomyces cerevisiae
-
Brunet S, Noueihed B, Shahrzad N, et al. The SMS domain of Trs23p is responsible for the in vitro appearance of the TRAPP I complex in Saccharomyces cerevisiae. Cell Logist 2012; 2:28-42.
-
(2012)
Cell Logist
, vol.2
, pp. 28-42
-
-
Brunet, S.1
Noueihed, B.2
Shahrzad, N.3
-
11
-
-
0032080081
-
TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion
-
Sacher M, Jiang Y, Barrowman J, et al. TRAPP, a highly conserved novel complex on the cis-Golgi that mediates vesicle docking and fusion. EMBO J 1998; 17:2494-2503.
-
(1998)
EMBO J
, vol.17
, pp. 2494-2503
-
-
Sacher, M.1
Jiang, Y.2
Barrowman, J.3
-
12
-
-
0033622037
-
Identification and characterization of five new subunits of TRAPP
-
Sacher M, Barrowman J, Schieltz D, Yates JR III, Ferro-Novick S. Identification and characterization of five new subunits of TRAPP. Eur J Cell Biol 2000; 79:71-80.
-
(2000)
Eur J Cell Biol
, vol.79
, pp. 71-80
-
-
Sacher, M.1
Barrowman, J.2
Schieltz, D.3
Yates III, J.R.4
Ferro-Novick, S.5
-
13
-
-
0035102194
-
TRAPP I implicated in the specificity of tethering in ER-to-Golgi transport
-
Sacher M, Barrowman J, Wang W, et al. TRAPP I implicated in the specificity of tethering in ER-to-Golgi transport. Mol Cell 2001; 7:433-442.
-
(2001)
Mol Cell
, vol.7
, pp. 433-442
-
-
Sacher, M.1
Barrowman, J.2
Wang, W.3
-
14
-
-
56149091013
-
The TRAPP complex: Insights into its architecture and function
-
Sacher M, Kim YG, Lavie A, Oh BH, Segev N. The TRAPP complex: Insights into its architecture and function. Traffic 2008; 9:2032-2042.
-
(2008)
Traffic
, vol.9
, pp. 2032-2042
-
-
Sacher, M.1
Kim, Y.G.2
Lavie, A.3
Oh, B.H.4
Segev, N.5
-
15
-
-
0034597055
-
Synbindin, a novel syndecan-2-binding protein in neuronal dendritic spines
-
Ethell IM, Hagihara K, Miura Y, Irie F, Yamaguchi Y. Synbindin, a novel syndecan-2-binding protein in neuronal dendritic spines. J Cell Biol 2000; 151:53-68.
-
(2000)
J Cell Biol
, vol.151
, pp. 53-68
-
-
Ethell, I.M.1
Hagihara, K.2
Miura, Y.3
Irie, F.4
Yamaguchi, Y.5
-
16
-
-
57749191527
-
Crystal structure of human synbindin reveals two conformations of longin domain
-
Fan S, Wei Z, Xu H, Gong W. Crystal structure of human synbindin reveals two conformations of longin domain. Biochem Biophys Res Commun 2009; 378:338-343.
-
(2009)
Biochem Biophys Res Commun
, vol.378
, pp. 338-343
-
-
Fan, S.1
Wei, Z.2
Xu, H.3
Gong, W.4
-
17
-
-
0033571145
-
Two antigens recognized by autologous cytolytic T lymphocytes on a melanoma result from a single point mutation in an essential housekeeping gene
-
Chiari R, Foury F, De Plaen E, Baurain JF, Thonnard J, Coulie PG. Two antigens recognized by autologous cytolytic T lymphocytes on a melanoma result from a single point mutation in an essential housekeeping gene. Cancer Res 1999; 59:5785-5792.
-
(1999)
Cancer Res
, vol.59
, pp. 5785-5792
-
-
Chiari, R.1
Foury, F.2
De Plaen, E.3
Baurain, J.F.4
Thonnard, J.5
Coulie, P.G.6
-
18
-
-
0032769695
-
Identification of the gene (SEDL) causing X-linked spondyloepiphyseal dysplasia tarda
-
Gedeon AK, Colley A, Jamieson R, et al. Identification of the gene (SEDL) causing X-linked spondyloepiphyseal dysplasia tarda. Nat Genet 1999; 22:400-404.
-
(1999)
Nat Genet
, vol.22
, pp. 400-404
-
-
Gedeon, A.K.1
Colley, A.2
Jamieson, R.3
-
19
-
-
71149100261
-
A truncating mutation of TRAPPC9 is associated with autosomal-recessive intellectual disability and postnatal microcephaly
-
Mochida GH, Mahajnah M, Hill AD, et al. A truncating mutation of TRAPPC9 is associated with autosomal-recessive intellectual disability and postnatal microcephaly. Am J Hum Genet 2009; 85:897-902.
-
(2009)
Am J Hum Genet
, vol.85
, pp. 897-902
-
-
Mochida, G.H.1
Mahajnah, M.2
Hill, A.D.3
-
20
-
-
79961094819
-
TRAPPC4-ERK2 interaction activates ERK1/2, modulates its nuclear localization and regulates proliferation and apoptosis of colorectal cancer cells
-
Zhao SL, Hong J, Xie ZQ, et al. TRAPPC4-ERK2 interaction activates ERK1/2, modulates its nuclear localization and regulates proliferation and apoptosis of colorectal cancer cells. PLoS ONE 2011; 6:e23262.
-
(2011)
PLoS ONE
, vol.6
-
-
Zhao, S.L.1
Hong, J.2
Xie, Z.Q.3
-
21
-
-
0344827261
-
Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells
-
Agarwal C, Singh RP, Dhanalakshmi S, et al. Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells. Oncogene 2003; 22:8271-8282.
-
(2003)
Oncogene
, vol.22
, pp. 8271-8282
-
-
Agarwal, C.1
Singh, R.P.2
Dhanalakshmi, S.3
-
22
-
-
53949096956
-
Silibinin inhibits cell growth and induces apoptosis by caspase activation, down-regulating survivin and blocking EGFR-ERK activation in renal cell carcinoma
-
Li L, Gao Y, Zhang L, Zeng J, He D, Sun Y. Silibinin inhibits cell growth and induces apoptosis by caspase activation, down-regulating survivin and blocking EGFR-ERK activation in renal cell carcinoma. Cancer Lett 2008; 272:61-69.
-
(2008)
Cancer Lett
, vol.272
, pp. 61-69
-
-
Li, L.1
Gao, Y.2
Zhang, L.3
Zeng, J.4
He, D.5
Sun, Y.6
-
23
-
-
0034812726
-
Infection of lymphoid cells by integration-defective human immunodeficiency virus type 1 increases de novo methylation
-
Fang JY, Mikovits JA, Bagni R, Petrow-Sadowski CL, Ruscetti FW. Infection of lymphoid cells by integration-defective human immunodeficiency virus type 1 increases de novo methylation. J Virol 2001; 75:9753-9761.
-
(2001)
J Virol
, vol.75
, pp. 9753-9761
-
-
Fang, J.Y.1
Mikovits, J.A.2
Bagni, R.3
Petrow-Sadowski, C.L.4
Ruscetti, F.W.5
-
24
-
-
80051540053
-
hSulf-1 gene exhibits anticancer efficacy through negatively regulating VEGFR-2 signaling in human cancers
-
Ji W, Yang J, Wang D, et al. hSulf-1 gene exhibits anticancer efficacy through negatively regulating VEGFR-2 signaling in human cancers. PLoS ONE 2011; 6:e23274.
-
(2011)
PLoS ONE
, vol.6
-
-
Ji, W.1
Yang, J.2
Wang, D.3
-
25
-
-
65949119310
-
How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer
-
Mebratu Y, Tesfaigzi Y. How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer? Cell Cycle 2009; 8:1168-1175.
-
(2009)
Cell Cycle
, vol.8
, pp. 1168-1175
-
-
Mebratu, Y.1
Tesfaigzi, Y.2
-
26
-
-
84855678871
-
PIK3CA mutation and methylation influences the outcome of colorectal cancer
-
Iida S, Kato S, Ishiguro M, et al. PIK3CA mutation and methylation influences the outcome of colorectal cancer. Oncol Lett 2012; 3:565-570.
-
(2012)
Oncol Lett
, vol.3
, pp. 565-570
-
-
Iida, S.1
Kato, S.2
Ishiguro, M.3
-
27
-
-
84862294189
-
ERK1/2 MAP kinases: Structure, function, and regulation
-
Roskoski R, Jr. ERK1/2 MAP kinases: Structure, function, and regulation. Pharmacol Res 2012; 66:105-143.
-
(2012)
Pharmacol Res
, vol.66
, pp. 105-143
-
-
Roskoski Jr, R.1
-
28
-
-
30944447568
-
The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions
-
Yoon S, Seger R. The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functions. Growth Factors 2006; 24:21-44.
-
(2006)
Growth Factors
, vol.24
, pp. 21-44
-
-
Yoon, S.1
Seger, R.2
-
29
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
30
-
-
34547209343
-
Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
-
McCubrey JA, Steelman LS, Chappell WH, et al. Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance. Biochim Biophys Acta 2007; 1773:1263-1284.
-
(2007)
Biochim Biophys Acta
, vol.1773
, pp. 1263-1284
-
-
McCubrey, J.A.1
Steelman, L.S.2
Chappell, W.H.3
-
31
-
-
0141534435
-
Mitogen-activated protein kinases (MAPK) as predictors of clinical outcome in serous ovarian carcinoma in effusions
-
Givant-Horwitz V, Davidson B, Lazarovici P, et al. Mitogen-activated protein kinases (MAPK) as predictors of clinical outcome in serous ovarian carcinoma in effusions. Gynecol Oncol 2003; 91:160-172.
-
(2003)
Gynecol Oncol
, vol.91
, pp. 160-172
-
-
Givant-Horwitz, V.1
Davidson, B.2
Lazarovici, P.3
-
32
-
-
33847117662
-
Activation of extracellular regulated kinases (ERK1/2) but not AKT predicts poor prognosis in colorectal carcinoma and is associated with k-ras mutations
-
Schmitz KJ, Wohlschlaeger J, Alakus H, et al. Activation of extracellular regulated kinases (ERK1/2) but not AKT predicts poor prognosis in colorectal carcinoma and is associated with k-ras mutations. Virchows Arch 2007; 450:151-159.
-
(2007)
Virchows Arch
, vol.450
, pp. 151-159
-
-
Schmitz, K.J.1
Wohlschlaeger, J.2
Alakus, H.3
-
34
-
-
0242441992
-
Expression of activated extracellular signal-regulated kinases 1/2 in malignant melanomas: Relationship with clinical outcome
-
Jorgensen K, Holm R, Maelandsmo GM, Flørenes VA. Expression of activated extracellular signal-regulated kinases 1/2 in malignant melanomas: Relationship with clinical outcome. Clin Cancer Res 2003; 9:5325-5331.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 5325-5331
-
-
Jorgensen, K.1
Holm, R.2
Maelandsmo, G.M.3
Flørenes, V.A.4
-
35
-
-
28544431984
-
Mutants in trs120 disrupt traffic from the early endosome to the late Golgi
-
Cai H, Zhang Y, Pypaert M, Walker L, Ferro-Novick S. Mutants in trs120 disrupt traffic from the early endosome to the late Golgi. J Cell Biol 2005; 171:823-833.
-
(2005)
J Cell Biol
, vol.171
, pp. 823-833
-
-
Cai, H.1
Zhang, Y.2
Pypaert, M.3
Walker, L.4
Ferro-Novick, S.5
-
36
-
-
77952329475
-
Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy
-
Lynch-Day MA, Bhandari D, Menon S, et al. Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy. Proc Natl Acad Sci USA 2010; 107:7811-7816.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 7811-7816
-
-
Lynch-Day, M.A.1
Bhandari, D.2
Menon, S.3
-
37
-
-
25844489089
-
Trs85 (Gsg1), a component of the TRAPP complexes, is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway
-
Meiling-Wesse K, Epple UD, Krick R, et al. Trs85 (Gsg1), a component of the TRAPP complexes, is required for the organization of the preautophagosomal structure during selective autophagy via the Cvt pathway. J Biol Chem 2005; 280:33669-33678.
-
(2005)
J Biol Chem
, vol.280
, pp. 33669-33678
-
-
Meiling-Wesse, K.1
Epple, U.D.2
Krick, R.3
-
38
-
-
33845345128
-
Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae
-
Nazarko TY, Huang J, Nicaud JM, Klionsky DJ, Sibirny AA. Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia lipolytica and Saccharomyces cerevisiae. Autophagy 2005; 1:37-45.
-
(2005)
Autophagy
, vol.1
, pp. 37-45
-
-
Nazarko, T.Y.1
Huang, J.2
Nicaud, J.M.3
Klionsky, D.J.4
Sibirny, A.A.5
-
39
-
-
20144384882
-
Lost in transcription: p21 Repression, mechanisms, and consequences
-
Gartel AL, Radhakrishnan SK. Lost in transcription: p21 Repression, mechanisms, and consequences. Cancer Res 2005; 65:3980-3985.
-
(2005)
Cancer Res
, vol.65
, pp. 3980-3985
-
-
Gartel, A.L.1
Radhakrishnan, S.K.2
-
40
-
-
34248563290
-
The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition
-
Meloche S, Pouysségur J. The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition. Oncogene 2007; 26:3227-3239.
-
(2007)
Oncogene
, vol.26
, pp. 3227-3239
-
-
Meloche, S.1
Pouysségur, J.2
-
41
-
-
13444311622
-
Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK
-
Chen CH, Wang WJ, Kuo JC, et al. Tsai HC, Lin JR, Chang ZF, Chen RH, Bidirectional signals transduced by DAPK-ERK interaction promote the apoptotic effect of DAPK. EMBO J 2005; 24:294-304.
-
(2005)
EMBO J
, vol.24
, pp. 294-304
-
-
Chen, C.H.1
Wang, W.J.2
Kuo, J.C.3
Tsai, H.C.4
Lin, J.R.5
Chang, Z.F.6
Chen, R.H.7
-
42
-
-
34347378526
-
The role of Trs65 in the Ypt/Rab guanine nucleotide exchange factor function of the TRAPP II complex
-
Liang Y, Morozova N, Tokarev AA, Mulholland JW, Segev N. The role of Trs65 in the Ypt/Rab guanine nucleotide exchange factor function of the TRAPP II complex. Mol Biol Cell 2007; 18:2533-2541.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 2533-2541
-
-
Liang, Y.1
Morozova, N.2
Tokarev, A.A.3
Mulholland, J.W.4
Segev, N.5
-
43
-
-
33847208186
-
Conservation of the TRAPPII-specific subunits of a Ypt/Rab exchanger complex
-
Cox R, Chen SH, Yoo E, Segev N. Conservation of the TRAPPII-specific subunits of a Ypt/Rab exchanger complex. BMC Evol Biol 2007; 7:12.
-
(2007)
BMC Evol Biol
, vol.7
, pp. 12
-
-
Cox, R.1
Chen, S.H.2
Yoo, E.3
Segev, N.4
-
44
-
-
33750499290
-
TRAPPII subunits are required for the specificity switch of a Ypt-Rab GEF
-
Morozova N, Liang Y, Tokarev AA, et al. TRAPPII subunits are required for the specificity switch of a Ypt-Rab GEF. Nat Cell Biol 2006; 8:1263-1269.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1263-1269
-
-
Morozova, N.1
Liang, Y.2
Tokarev, A.A.3
-
45
-
-
0034997845
-
Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions
-
Pearson G, Robinson F, Beers Gibson T, et al. Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions. Endocrinol Rev 2001; 22:53-83.
-
(2001)
Endocrinol Rev
, vol.22
, pp. 53-83
-
-
Pearson, G.1
Robinson, F.2
Beers Gibson, T.3
-
46
-
-
85047697320
-
ERK signalling and oncogene transformation are not impaired in cells lacking A-Raf
-
Mercer K, Chiloeches A, Huser M, Kiernan M, Marais R, Pritchard C. ERK signalling and oncogene transformation are not impaired in cells lacking A-Raf. Oncogene 2002; 21:347-355.
-
(2002)
Oncogene
, vol.21
, pp. 347-355
-
-
Mercer, K.1
Chiloeches, A.2
Huser, M.3
Kiernan, M.4
Marais, R.5
Pritchard, C.6
|