Activation of extracellular regulated kinases (ERK1/2) but not AKT predicts poor prognosis in colorectal carcinoma and is associated with k-ras mutations

Virchows Archiv

Volumn 450, Issue 2, 2007, Pages 151-159

  Schmitz, K J ^a   Wohlschlaeger, J ^a   Alakus, H ^b   Bohr, J ^a   Stauder, M A ^a   Worm, K ^a   Winde, G ^b   Schmid, K W ^a   Baba, H A ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b Klinikum Herford   (Germany)

Author keywords

Colorectal cancer; Molecular oncology

Indexed keywords

CYCLIN D1; CYCLOOXYGENASE 2; K RAS PROTEIN; KI 67 ANTIGEN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; COLORECTAL CARCINOMA; DISEASE ASSOCIATION; ENZYME ACTIVATION; GENE MUTATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROGNOSIS;

COLORECTAL NEOPLASMS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENES, RAS; HUMANS; MALE; MUTATION; PHOSPHORYLATION; PROGNOSIS; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 33847117662     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-006-0342-y     Document Type: Article

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