SOCS-1 Protein Prevents Janus Kinase/STAT-dependent Inhibition of β Cell Insulin Gene Transcription and Secretion in Response to Interferon-γ

Journal of Biological Chemistry

Volumn 276, Issue 28, 2001, Pages 25862-25870

  Cottet, Sandra ^b   Dupraz, Philippe ^b   Hamburger, Fabienne ^b   Dolci, Wanda ^b   Jaquet, Muriel ^b   Thorens, Bernard ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; ENZYME INHIBITION; GENES; GLUCOSE; INSULIN; PROTEINS; RNA;

CELL DYFUNCTION; GENE TRANSCRIPTION;

BIOCHEMISTRY;

CYTOKINE; GAMMA INTERFERON; GLUCOSE; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; INTERLEUKIN 1BETA; JANUS KINASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROTEIN; STAT PROTEIN; STAT1 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CARRIER PROTEIN; DNA BINDING PROTEIN; JAK1 PROTEIN, HUMAN; JAK2 PROTEIN, HUMAN; JANUS KINASE 1; JANUS KINASE 2; ONCOPROTEIN; PROTEIN TYROSINE KINASE; REPRESSOR PROTEIN; SIGNAL PEPTIDE; SOCS1 PROTEIN, HUMAN; STAT1 PROTEIN, HUMAN; SUPPRESSOR OF CYTOKINE SIGNALING; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL LINE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ENZYME INHIBITION; GENE; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN GENE; INSULIN PROMOTER LUCIFERASE REPORTER GENE; INSULIN RELEASE; INSULIN SYNTHESIS; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SOCS 1 GENE; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; PHYSIOLOGY; SECRETION;

ANIMALIA; JANUS;

ANIMALS; CARRIER PROTEINS; CELL LINE; DIABETES MELLITUS, TYPE 1; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HUMANS; INSULIN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISLETS OF LANGERHANS; JANUS KINASE 1; JANUS KINASE 2; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRANS-ACTIVATORS;

EID: 0035854646     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M103235200     Document Type: Article

References (56)

1. Dupraz, P., Cottet, S., Hamburger, F., Dolci, W., Felley-Bosco, E., and Thorens, B. (2000) J. Biol. Chem. 275, 37672-37678
2. Kay, T. W. H., Thomas, H. E., Harrison, L. C., and Allison, J. (2000) Trends Endocrinol. Metab. 11, 11-15
3. Rabinovitch, A. (1998) Diabetes Metab. Rev. 14, 129-151
4. Katz, J. D., Benoist, C., and Mathis, D. (1995) Science 268, 1185-1188
5. Kallmann, B. A., Huther, M., Tubes, M., Feldkamp, J., Bertrams, J., Gries, F. A., Lampeter, E. F., and Kolb, H. (1997) Diabetes 46, 237-243
6. Wilson, S. B., Kent, S. C., Patton, K. T., Orban, T., Jackson, R. A., Exley, M., Porcelli, S., Schatz, D. A., Atkinson, M. A., Balk, S. P., Strominger, J. L., and Hafler, D. A. (1998) Nature 391, 177-181
7. von Herrath, M. G., and Oldstone, M. B. (1997) J. Exp. Med. 185, 531-539
8. Wang, B., Andre, I., Gonzalez, A., Katz, J. D., Aguet, M., Benoist, C., and Mathis, D. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 13844-13849
9. Hultgren, B., Huang, X., Dybdal, N., and Stewart, T. A. (1996) Diabetes 45, 812-817
10. Thomas, H. E., Parker, J. L., Schreiber, R. D., and Kay, T. W. (1998) J. Clin. Invest. 102, 1249-1257
11. Campbell, I. L., and Harrison, L. C. (1990) Mol. Biol. Med. 7, 299-309
12. Baldeon, M. E., Neece, D. J., Nandi, D., Monaco, J. J., and Gaskins, H. R. (1997) Diabetes 46, 770-778
13. Yagi, N., Yokono, K., Amano, K., Nagata, M., Tsukamoto, K., Hasegawa, Y., Yoneda, R., Okamoto, N., Moriyama, H., Miki, M., et al. (1995) Diabetes 44, 744-752
14. Eizirik, D. L., Flodstrom, M., Karlsen, A. E., and Welsh, N. (1996) Diabetologia 39, 875-890
15. Eizirik, D. L., Sandler, S., Welsh, N., Cetkovic-Cvrlje, M., Nieman, A., Geller, D. A., Pipeleers, D. G., Bendtzen, K., and Hellerstrom, C. (1994) J. Clin. Invest. 93, 1968-1974
16. Rabinovitch, A., Suarez-Pinzon, W. L., Strynadka, K., Schulz, R., Lakey, J. R., Warnock, G. L., and Rajotte, R. V. (1994) J. Clin. Endocrinol. Metab. 79, 1058-1062
17. Rabinovitch, A., and Suarez-Pinzon, W. L. (1998) Biochem. Pharmacol. 55, 1139-1149
18. Suarez-Pinzon, W. L., Strynadka, K., Schulz, R., and Rabinovitch, A. (1994) Endocrinology 134, 1006-1010
19. Zumsteg, U., Frigerio, S., and Hollander, G. A. (2000) Diabetes 49, 39-47
20. Rabinovitch, A., Suarez-Pinzon, W. L., Shi, Y., Morgan, A. R., and Bleackley, R. C. (1994) Diabetologia 37, 733-738
21. Greenlund, A. C., Farrar, M. A., Viviano, B. L., and Schreiber, R. D. (1994) EMBO J. 13, 1591-1600
22. Darnell, J. E., Kerr, I. M., and Stark, G. R. (1994) Science 264, 1415-1421
23. Darnell, J. E. (1997) Science 277, 1630-1635
24. Yoshimura, A., Ohkubo, T., Kiguehi T., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., Hara, T., and Miyajima, A. (1995) EMBO J. 14, 2816-2826
25. Yasukawa, H., Sasaki, A., and Yoshimura, A. (2000) Annu. Rev. Immunol. 18, 143-164
26. Endo, T. A., Masuhara, M., Yokouchi, M., Suzuki, R., Sakamoto, H., Mitsui, K., Matsumoto, A., Tanimura, S., Ohtsubo, M., Misawa, H., Miyazaki, T., Leonor, N., Taniguchi, T., Fujita, T., Kanakura, Y., Komiya, S., and Yoshimura, A. (1997) Nature 387, 921-924
27. Naka, T., Narazaki, M., Hirata, M., Matsumoto, T., Minamoto, S., Aono, A., Nishimoto, N., Kajita, T., Taga, T., Yoshizaki, K., Akira, S., and Kishimoto, T. (1997) Nature 387, 924-929
28. Starr, R., Willson, T. A., Viney, E. M., Murray, L. J., Rayner, J. R., Jenkins, B. J., Gonda, T. J., Alexander, W. S., Metealf, D., Nieola, N. A., and Hilton, D. J. (1997) Nature 387, 917-921
29. Yasukawa, H., Misawa, H., Sakamoto, H., Masuhara, M., Sasaki, A., Wakioka, T., Ohtsuka, S., Imaizumi, T., Matsuda, T., Ihle, J. N., and Yoshimura, A. (1999) EMBO J. 18, 1309-1320
30. Suzuki, R., Sakamoto, H., Yasukawa, H., Masuhara, M., Wakioka, T., Sasaki, A., Yuge, K., Komiya, S., Inoue, A., and Yoshimura, A. (1998) Oncogene 17, 2271-2278
31. Sakamoto, H., Yasukawa, H., Masuhara, M., Tanimura, S., Sasaki, A., Yuge, K., Ohtsubo, M., Ohtsuka, A., Fujita, T., Ohta, T., Furukawa, Y., Iwase, S., Yamada, H., and Yoshimura, A. (1998) Blood 92, 1668-1676
32. Naka, T., Matsumoto, T., Narazaki, M., Fujimoto, M., Morita, Y., Ohsawa, Y., Saito, H., Nagasawa, T., Uchiyama, Y., and Kishimoto, T. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 15577-15582
33. Starr, R., Metcalf, D., Elefanty, A. G., Brysha, M., Willson, T. A., Nicola, N. A., Hilton, D. J., and Alexander, W. S. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 14395-14399
34. Alexander, W. S., Starr, R., Fenner, J. E., Scott, C. L., Handman, E., Sprigg, N. S., Corbin, J. E., Cornish, A. L., Darwiche, R., Owczarek, C. M., Kay, T. W., Nicola, N. A., Hertzog, P. J., Metcalf, D., and Hilton, D. J. (1999) Cell 98, 597-608
35. Marine, J. C., Topham, D. J., McKay, C., Wang, D., Parganas, E., Stravopodis, D., Yoshimura, A., and Ihle, J. N. (1999) Cell 98, 609-616
36. Efrat, S., Fusco-DeMane, D., Lemberg, H., al Emran, O., and Wang, X. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 3576-3580
37. Dupraz, P., Rinsch, C., Pralong, W. F., Rolland, E., Zufferey, R., Trono, D., and Thorens, B. (1999) Gene Ther. 6, 1160-1169
38. Gremlich, S., Bonny, C., Waeber, G., and Thorens, B. (1997) J. Biol. Chem. 272, 30261-30269
39. Zufferey, R., Dull, T., Mandel, R. J., Bukovsky, A., Quiroz, D., Naldini, L., and Trono, D. (1993) J. Virol. 72, 9873-9880
40. Zufferey, R., Donello, J. E., Trono, D., and Hope, T. J. (1999) J. Virol. 73, 2886-2892
41. Naldini, L., Blomer, U., Gallay, P., Ory, D., Mulligan, R., Gage, F. H., Verma, I. M., and Trono, D. (1996) Science 272, 263-267
42. Zufferey, R., Nagy, D., Mandel, R. J., Naldini, L., and Trono, D. (1997) Nat. Biotechnol. 15, 871-875
43. Guillam, M. T., Hummler, E., Schaerer, E., Yeh, J. I., Birnbaum, M. J., Beermann, F., Schmidt, A., Deriaz, N., Thorens, B., and Wu, J. Y. (1997) Nat. Genet. 17, 327-330
44. Rago, R., Mitchen, J., and Wilding, G. (1990) Anal. Biochem. 191, 31-34
45. Green, L. C., Wagner, D. A., Glogowski, J., Skipper, P. L., Wishnok, J. S., and Tannenbaum, S. R. (1982) Anal. Biochem. 126, 131-138
46. Gremlich, S., Roduit, R., and Thorens, B. (1997) J. Biol. Chem. 272, 3216-3222
47. Olson, L. K., Redmon, J. B., Towle, H. C., and Robertson, R. P. (1993) J. Clin. Invest. 92, 514-519
48. Campbell, I. L., Iscaro, A., and Harrison, L. C. (1988) J. Immunol. 141, 2325-2329
49. Dunger, A., Cunningham, J. M., Delaney, C. A., Lowe, J. E., Green, M. H., Bone, A. J., and Green, I. C. (1996) Diabetes 45, 183-189
50. Sternesjo, J., Bendtzen, K., and Sandler, S. (1995) Autoimmunity 20, 185-190
51. Ramana, C. V., Grammatikakis, N., Chernov, M., Nguyen, H., Goh, K. C., Williams, B. R., and Stark, G. R. (2000) EMBO J. 19, 263-272
52. Galsgaard, E. D., Gouilleux, F., Groner, B., Serup, P., Nielsen, J. H., and Billestrup, N. (1996) Mol. Endocrinol. 10, 652-660
53. Heitmeier, M. R., Scarim, A. L., and Corbett, J. A. (1999) J. Biol. Chem. 274, 29266-29273
54. Adams, T. E., Hansen, J. A., Starr, R., Nicola, N. A., Hilton, D. J., and Billestrup, N. (1998) J. Biol. Chem. 273, 1285-1287
55. Song, M. M., and Shuai, K. (1998) J. Biol. Chem. 273, 35056-35062
56. Ito, S., Ansari, P., Sakatsume, M., Dickensheets, H., Vazquez, N., Donnelly, R. P., Lamer, A. C., and Finbloom, D. S. (1999) Blood 93, 1456-1463