MrgC agonism at central terminals of primary sensory neurons inhibits neuropathic pain

Pain

Volumn 155, Issue 3, 2014, Pages 534-544

  He, Shao Qiu ^a   Li, Zhe ^a   Chu, Yu Xia ^b   Han, Liang ^a   Xu, Qian ^a   Li, Man ^b   Yang, Fei ^a   Liu, Qin ^a   Tang, Zongxiang ^a   Wang, Yun ^c   Hin, Niyada ^d   Tsukamoto, Takashi ^a,d   Slusher, Barbara ^a,d   Tiwari, Vinod ^a   Shechter, Ronen ^a   Wei, Feng ^b   Raja, Srinivasa N ^a   Dong, Xinzhong ^a   Guan, Yun ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND DENTAL SCHOOL   (United States)

^c CAPITAL MEDICAL UNIVERSITY   (China)

^d JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Analgesia; Dorsal root ganglion; MrgC; Neuropathic pain

Indexed keywords

ANALGESIC AGENT; BAM 8 22; G PROTEIN COUPLED RECEPTOR; JHU 58; MAS RELATED G PROTEIN COUPLED RECEPTOR SUBTYPE C; MESSENGER RNA; PHENYLALANYLMETHIONYLARGINYLPHENYLALANINAMIDE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; BLASTOCYST; CELL STRAIN HEK293; CHRONIC CONSTRICTION INJURY; CONTROLLED STUDY; EMBRYO; HARGREAVES TEST; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; HYPERSENSITIVITY; IMMUNOFLUORESCENCE; IN VITRO STUDY; MALE; MOUSE; NERVE LIGATION; NEUROPATHIC PAIN; NONHUMAN; PATCH CLAMP TECHNIQUE; PINPRICK TEST; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ROTAROD TEST; SENSORY NERVE CELL; SPINAL CORD DORSAL HORN; SPINAL GANGLION; SUBSTANTIA GELATINOSA; TRIGEMINAL NERVE INJURY;

ANALGESIA; DORSAL ROOT GANGLION; MRGC; NEUROPATHIC PAIN;

ANIMALS; CELLS, CULTURED; EXCITATORY POSTSYNAPTIC POTENTIALS; HEK293 CELLS; HUMANS; INJECTIONS, SPINAL; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURALGIA; PAIN MEASUREMENT; PEPTIDE FRAGMENTS; PRESYNAPTIC TERMINALS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; SENSORY RECEPTOR CELLS;

EID: 84894252300     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2013.12.008     Document Type: Article

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