Activation of Mas oncogene-related gene (Mrg) C receptors enhances morphine-induced analgesia through modulation of coupling of μ-opioid receptor to Gi-protein in rat spinal dorsal horn

Neuroscience

Volumn 253, Issue , 2013, Pages 455-464

  Wang, D ^a   Chen, T ^a   Zhou, X ^a   Couture, R ^b   Hong, Y ^a  

^a FUJIAN NORMAL UNIVERSITY   (China)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

opioid receptors; Dorsal root ganglia; G proteins; Mas oncogene related gene (Mrg); Morphine analgesia; Spinal dorsal horn

Indexed keywords

BAM 8 22; G PROTEIN COUPLED RECEPTOR; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA; MORPHINE; MRGC RECEPTOR; MU OPIATE RECEPTOR; OPIATE AGONIST; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; CYTOPLASM; DOSE RESPONSE; DRUG POTENCY; IN VIVO STUDY; MALE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; SPINAL CORD DORSAL HORN; SPINAL GANGLION;

(G PROTEIN)-COUPLED RECEPTOR; ANALYSIS OF VARIANCE; ANOVA; DORSAL ROOT GANGLIA; DRG; EDTA; ETHYLENEDIAMINETETRAACETIC ACID; G PROTEINS; GPCR; MAS ONCOGENE-RELATED GENE; MAS ONCOGENE-RELATED GENE (MRG); MAXIMUM POSSIBLE EFFECT; MOR; MORPHINE ANALGESIA; MPE; MRG; PB; PBS; PHOSPHATE BUFFER; PHOSPHATE-BUFFERED SALINE; REAL-TIME-POLYMERASE CHAIN REACTION; RT-PCR; SPINAL DORSAL HORN; TAIL-FLICK LATENCY; TFL; Μ-OPIOID RECEPTOR; Μ-OPIOID RECEPTORS;

ANALGESICS, OPIOID; ANIMALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; GANGLIA, SPINAL; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; MALE; MORPHINE; NEURONS; ORGAN CULTURE TECHNIQUES; PAIN; PAIN MEASUREMENT; PEPTIDE FRAGMENTS; PROTO-ONCOGENE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, OPIOID, MU;

EID: 84885400822     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2013.08.069     Document Type: Article

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